| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tatyana Y Postnikova, Alina M Trofimova, Maria V Zakharova, Olga I Nosova, Alexey R Brazhe, Dmitry E Korzhevskii, Alexey V Semyanov, Aleksey V Zaitse. Delayed Impairment of Hippocampal Synaptic Plasticity after Pentylenetetrazole-Induced Seizures in Young Rats. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362260. |
delayed impairment of hippocampal synaptic plasticity after pentylenetetrazole-induced seizures in young rats. |
2022-11-11 |
2023-08-14 |
rat |
| Nikita Zernov, Alexander V Veselovsky, Vladimir V Poroikov, Daria Melentieva, Anastasia Bolshakova, Elena Popugaev. New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362339. |
we demonstrate that it binds to the extracellular agonist binding site of the human trpc6, protects hippocampal mushroom spines from amyloid toxicity in vitro, efficiently recovers synaptic plasticity in 5xfad brain slices, penetrates the blood-brain barrier and recovers cognitive deficits in 5xfad mice. |
2022-11-11 |
2023-08-14 |
mouse |
| Shirin Hosseini, Marco van Ham, Christian Erck, Martin Korte, Kristin Michaelsen-Preuss. The role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons. Frontiers in molecular neuroscience. vol 15. 2022-11-07. PMID:36340693. |
ttl loss was also associated with a deficit in spatial learning, impaired synaptic plasticity, and reduced number of spines in hippocampal neurons, suggesting that ttl also plays a critical role in hippocampal network development. |
2022-11-07 |
2023-08-14 |
mouse |
| Zhuo Ma, Kuan Liu, Rui-Feng Zhang, Zi-Xin Xie, Wei Liu, Yu Deng, Xin Li, Bin X. Manganese-induced α-synuclein overexpression promotes the accumulation of dysfunctional synaptic vesicles and hippocampal synaptotoxicity by suppressing Rab26-dependent autophagy in presynaptic neurons. The Science of the total environment. vol 858. issue Pt 1. 2022-11-07. PMID:36341850. |
the results of the in vivo experiments showed that 100 and 200 μmol/kg mn exposure significantly impaired memory and synaptic plasticity in the mice, which was related to the accumulation of impaired svs in the hippocampus. |
2022-11-07 |
2023-08-14 |
mouse |
| Ignacio Vega-Vásquez, Pedro Lobos, Jorge Toledo, Tatiana Adasme, Andrea Paula-Lima, Cecilia Hidalg. Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform. Biochemical and biophysical research communications. vol 633. 2022-11-07. PMID:36344175. |
the hippocampus is a brain region implicated in synaptic plasticity and memory formation; both processes require neuronal ca |
2022-11-07 |
2023-08-14 |
Not clear |
| Giuseppe Talani, Francesca Biggio, Ashish Avinash Gorule, Valentina Licheri, Eleonora Saolini, Daniele Colombo, Gabriele Sarigu, Michele Petrella, Francescangelo Vedele, Giovanni Biggio, Enrico Sann. Sex-dependent changes of hippocampal synaptic plasticity and cognitive performance in C57BL/6J mice exposed to neonatal repeated maternal separation. Neuropharmacology. 2022-11-06. PMID:36336069. |
sex-dependent changes of hippocampal synaptic plasticity and cognitive performance in c57bl/6j mice exposed to neonatal repeated maternal separation. |
2022-11-06 |
2023-08-14 |
mouse |
| Giuseppe Talani, Francesca Biggio, Ashish Avinash Gorule, Valentina Licheri, Eleonora Saolini, Daniele Colombo, Gabriele Sarigu, Michele Petrella, Francescangelo Vedele, Giovanni Biggio, Enrico Sann. Sex-dependent changes of hippocampal synaptic plasticity and cognitive performance in C57BL/6J mice exposed to neonatal repeated maternal separation. Neuropharmacology. 2022-11-06. PMID:36336069. |
we here investigated the influence of rms exposure on hippocampal inhibitory and excitatory synaptic transmission, long-term synaptic plasticity as well as the related potential alterations in learning and memory performance in adult male and female c57bl/6j mice. |
2022-11-06 |
2023-08-14 |
mouse |
| Elisabetta Gerace, Lorenzo Polenzani, Maurizio Magnani, Elisa Zianni, Gabriella Stocca, Fabrizio Gardoni, Domenico E Pellegrini-Giampietro, Renato Corradett. Antidepressant-induced increase in GluA2 expression does not translate in changes of AMPA receptor-mediated synaptic transmission at CA3/CA1 synapses in rats. Neuropharmacology. 2022-11-05. PMID:36334766. |
these changes in ampar composition have been suggested to result in increased glutamatergic neurotransmission and possibly underlie enhanced hippocampal synaptic plasticity through the increased availability of calcium-permeable ampars, specifically at ca3/ca1 synapses. |
2022-11-05 |
2023-08-14 |
rat |
| Kunwei Wu, Wenyan Han, Wei L. Sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity. PLoS biology. vol 20. issue 11. 2022-11-01. PMID:36318572. |
sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity. |
2022-11-01 |
2023-08-14 |
mouse |
| Chiye Aoki, Adrienne N Santiag. Pathway-specific GABAergic inhibition contributes to the gain of resilience against anorexia-like behavior of adolescent female mice. Frontiers in behavioral neuroscience. vol 16. 2022-10-31. PMID:36311865. |
our findings point to the cellular and molecular underpinnings of three aba phenomena: (1) age-dependence of aba vulnerability; (2) individual differences in the persistence of aba vulnerability during adolescence; (3) gabaergic synaptic plasticity in the hippocampus and the prefrontal cortex that contributes to the suppression of the maladaptive anorexia-like behaviors. |
2022-10-31 |
2023-08-14 |
mouse |
| Raffaela Silvestre Ignarro, André Luis Bombeiro, Gabriela Bortolança Chiarotto, Luciana Politti Cartarozzi, Lilian de Oliveira Coser, Enrico Ghizoni, Helder Tedeschi, Fernando Cendes, Iscia Lopes-Cendes, Fabio Rogerio, Alexandre Leite Rodrigues de Oliveir. Interferon-beta induces major histocompatibility complex of class I (MHC-I) expression and a proinflammatory phenotype in cultivated human astrocytes. Differentiation; research in biological diversity. vol 128. 2022-10-28. PMID:36306693. |
as knowledge about mhc-i and its role in synaptic plasticity in human astrocytes (has) is scarce, we investigated these aspects in mature has obtained from the neocortex of patients undergoing surgery due to hippocampal sclerosis. |
2022-10-28 |
2023-08-14 |
mouse |
| Alexandra V Griflyuk, Tatyana Y Postnikova, Aleksey V Zaitse. Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293077. |
prolonged febrile seizures impair synaptic plasticity and alter developmental pattern of glial fibrillary acidic protein (gfap)-immunoreactive astrocytes in the hippocampus of young rats. |
2022-10-27 |
2023-08-14 |
rat |
| Yu-Zhi Jia, Hai-Tao Li, Guang-Ming Zhang, Hong-Yun Wu, Si-Shuo Zhang, Hong-Wei Zhi, Ya-Han Wang, Jing-Wen Zhu, Yi-Fan Wang, Xiang-Qing Xu, Cai-Jun Tian, Wen-Qiang Cu. Electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the CA1 hippocampal region in a mouse model of trigeminal neuralgia. Frontiers in molecular neuroscience. vol 15. 2022-10-24. PMID:36277498. |
electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the ca1 hippocampal region in a mouse model of trigeminal neuralgia. |
2022-10-24 |
2023-08-14 |
mouse |
| Wen-Rui Gao, Xiao-Hong Hu, Kai-Yue Yu, Hong-Yan Cai, Zhao-Jun Wang, Lei Wang, Mei-Na W. Selective Orexin 1 Receptor Antagonist SB-334867 Aggravated Cognitive Dysfunction in 3xTg-AD Mice. Behavioural brain research. 2022-10-24. PMID:36280008. |
the results showed that chronic ox1r blockade aggravated the impairments of short-term working memory, long-term spatial memory and synaptic plasticity in 9-month-old female 3xtg-ad mice, increased levels of soluble aβ oligomers and p-tau, and decreased psd-95 expression in the hippocampus of 3xtg-ad mice. |
2022-10-24 |
2023-08-14 |
mouse |
| Mohamad Azmeer Effendy, Suleiman Yunusa, Noorul Hamizah Mat, Ahmad Tarmizi Che Has, Christian P Müller, Zurina Hassa. The role of AMPA and NMDA receptors in mitragynine effects on hippocampal synaptic plasticity. Behavioural brain research. 2022-10-23. PMID:36273648. |
the role of ampa and nmda receptors in mitragynine effects on hippocampal synaptic plasticity. |
2022-10-23 |
2023-08-14 |
rat |
| Mohamad Azmeer Effendy, Suleiman Yunusa, Noorul Hamizah Mat, Ahmad Tarmizi Che Has, Christian P Müller, Zurina Hassa. The role of AMPA and NMDA receptors in mitragynine effects on hippocampal synaptic plasticity. Behavioural brain research. 2022-10-23. PMID:36273648. |
here, we determined the role of ampa- and nmda glutamate receptors in mitragynine-induced synaptic plasticity in the hippocampus. |
2022-10-23 |
2023-08-14 |
rat |
| Defeng Xu, Mouming Zha. Walnut protein hydrolysates ameliorate alcohol-induced cognitive impairment (AICI) by alleviating oxidative stress and inflammation in the brain and improving hippocampal synaptic plasticity in Sprague-Dawley rats. Food & function. 2022-10-21. PMID:36268846. |
walnut protein hydrolysates ameliorate alcohol-induced cognitive impairment (aici) by alleviating oxidative stress and inflammation in the brain and improving hippocampal synaptic plasticity in sprague-dawley rats. |
2022-10-21 |
2023-08-14 |
rat |
| Yan Niu, Pan Chang, Tian Liu, Xi Shen, Hui Zhao, Mingxia Zhang, Shengping Lei, Baoying Chen, Jun Y. Obese mice induced by high-fat diet have differential expression of circular RNAs involved in endoplasmic reticulum stress and neuronal synaptic plasticity of hippocampus leading to obesity-associated cognitive impairment. Frontiers in molecular neuroscience. vol 15. 2022-10-20. PMID:36263377. |
obese mice induced by high-fat diet have differential expression of circular rnas involved in endoplasmic reticulum stress and neuronal synaptic plasticity of hippocampus leading to obesity-associated cognitive impairment. |
2022-10-20 |
2023-08-14 |
mouse |
| Yan Niu, Pan Chang, Tian Liu, Xi Shen, Hui Zhao, Mingxia Zhang, Shengping Lei, Baoying Chen, Jun Y. Obese mice induced by high-fat diet have differential expression of circular RNAs involved in endoplasmic reticulum stress and neuronal synaptic plasticity of hippocampus leading to obesity-associated cognitive impairment. Frontiers in molecular neuroscience. vol 15. 2022-10-20. PMID:36263377. |
finally, we examined the deficits of hippocampal synaptic plasticity and detected the expression of er stress-related protein. |
2022-10-20 |
2023-08-14 |
mouse |
| Yan Niu, Pan Chang, Tian Liu, Xi Shen, Hui Zhao, Mingxia Zhang, Shengping Lei, Baoying Chen, Jun Y. Obese mice induced by high-fat diet have differential expression of circular RNAs involved in endoplasmic reticulum stress and neuronal synaptic plasticity of hippocampus leading to obesity-associated cognitive impairment. Frontiers in molecular neuroscience. vol 15. 2022-10-20. PMID:36263377. |
the results showed that er stress was activated in the hippocampus, and hippocampal synaptic plasticity deficits were displayed. |
2022-10-20 |
2023-08-14 |
mouse |