| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Deng, Junqing Zou, Ye Hong, Qiang Peng, Xinxin Fu, Rui Duan, Jie Chen, Xiangliang Che. Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats. Cells. vol 11. issue 22. 2022-11-26. PMID:36429082. |
tmao administration, which increased plasma and hippocampal tmao at 4 weeks postoperatively, further aggravated these effects, resulting in exaggerated cognitive and synaptic plasticity impairment, though not within the sham group. |
2022-11-26 |
2023-08-14 |
rat |
| Siavash Parvardeh, Mohammad Abbas Sheikholeslami, Shiva Ghafghazi, Ramin Pouriran, Seyed Erfan Mortazav. Minocycline Improves Memory by Enhancing Hippocampal Synaptic Plasticity and Restoring Antioxidant Enzyme Activity in a Rat Model of Cerebral Ischemia-Reperfusion. Basic and clinical neuroscience. vol 13. issue 2. 2022-11-25. PMID:36425949. |
minocycline improves memory by enhancing hippocampal synaptic plasticity and restoring antioxidant enzyme activity in a rat model of cerebral ischemia-reperfusion. |
2022-11-25 |
2023-08-14 |
rat |
| Briana K Chen, Christine A Denn. Weapons of stress reduction: (R,S)-ketamine and its metabolites as prophylactics for the prevention of stress-induced psychiatric disorders. Neuropharmacology. 2022-11-25. PMID:36427554. |
due to the broad neurobiological actions of (r,s)-ketamine, a variety of mechanisms have been proposed to contribute to the resilience-enhancing effects of this drug, including altering various transcription factors across the genome, enhancing inhibitory connections from the prefrontal cortex, and increasing synaptic plasticity in the hippocampus. |
2022-11-25 |
2023-08-14 |
Not clear |
| Xuying Li, Qian Zhai, Xingchun Gou, Minxue Quan, Yansong Li, Xiaohua Zhang, Bin Deng, Yi Tian, Qiang Wang, Lichao Ho. Involvement of Paired Immunoglobulin-Like Receptor B in Cognitive Dysfunction Through Hippocampal-Dependent Synaptic Plasticity Impairments in Mice Subjected to Chronic Sleep Restriction. Molecular neurobiology. 2022-11-23. PMID:36417104. |
our study sheds new light on the role of pirb as an important mediator in modulating the dysfunction of synaptic plasticity and cognitive function via the rhoa/rock2/limk1/cofilin signalling pathway, which indicated that hippocampal pirb is a promising therapeutic target for counteracting cognitive impairment after csr. |
2022-11-23 |
2023-08-14 |
mouse |
| Jiuyang Ding, Jian Huang, Xiang Tang, Lingyi Shen, Shanshan Hu, Jiaojiao He, Ting Liu, Zhixing Yu, Yubo Liu, Qiyan Wang, Jiawen Wang, Na Zhao, Xiaolan Qi, Jiang Huan. Low and high dose methamphetamine differentially regulate synaptic structural plasticity in cortex and hippocampus. Frontiers in cellular neuroscience. vol 16. 2022-11-21. PMID:36406748. |
we provided evidence that low and high doses of meth differentially regulate synaptic plasticity in cortex and hippocampus. |
2022-11-21 |
2023-08-14 |
Not clear |
| Shahab Ghaderi, Alireza Komaki, Iraj Salehi, Zahra Basir, Masome Rashn. Possible mechanisms involved in the protective effects of chrysin against lead-induced cognitive decline: An in vivo study in a rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-11-19. PMID:36402029. |
on day 56, hippocampal synaptic plasticity (long-term potentiation; ltp) was recorded in perforant path-dentate gyrus (pp-dg) synapses to assess field excitatory postsynaptic potentials (fepsps) slope and population spike (ps) amplitude. |
2022-11-19 |
2023-08-14 |
rat |
| Laifa Wang, Xueqin Wang, Ling Deng, Hui Zhang, Binsheng He, Wenyu Cao, Yanhui Cu. Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. International immunopharmacology. vol 113. issue Pt B. 2022-11-17. PMID:36395673. |
pexidartinib (plx3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. |
2022-11-17 |
2023-08-14 |
mouse |
| Zarei Fatemeh, Moazedi Ahmad Ali, Salimi Zahra, Pourmotabbed Ali, Yousofvand Namdar, Moradpour Farshad, Akrami Mohammad Rez. Activation of androgen receptors alters hippocampal synaptic plasticity and memory retention through modulation of L-type calcium channels. Life sciences. 2022-11-15. PMID:36379312. |
activation of androgen receptors alters hippocampal synaptic plasticity and memory retention through modulation of l-type calcium channels. |
2022-11-15 |
2023-08-14 |
Not clear |
| Maïthé Loisy, Amel Farah, Assia Fafouri, Aurélien Fanton, Mahboubeh Ahmadi, Ludivine Therreau, Vivien Chevaleyre, Rebecca A Piskorowsk. Environmental enrichment and social isolation modulate inhibitory transmission and plasticity in hippocampal area CA2. Hippocampus. 2022-11-14. PMID:36374115. |
the goal of this study was to examine how environmental conditions altered synaptic plasticity in hippocampal area ca2. |
2022-11-14 |
2023-08-14 |
mouse |
| Maïthé Loisy, Amel Farah, Assia Fafouri, Aurélien Fanton, Mahboubeh Ahmadi, Ludivine Therreau, Vivien Chevaleyre, Rebecca A Piskorowsk. Environmental enrichment and social isolation modulate inhibitory transmission and plasticity in hippocampal area CA2. Hippocampus. 2022-11-14. PMID:36374115. |
we then performed whole-cell or extracellular field recordings in hippocampal area ca2 and compared the synaptic plasticity from ee-housed mice with slices from littermate controls housed in standard environment (se). |
2022-11-14 |
2023-08-14 |
mouse |
| Siu Hin Lau, Ching Han Young, Yilin Zheng, Xi Che. The potential role of the cholecystokinin system in declarative memory. Neurochemistry international. 2022-11-14. PMID:36375634. |
subsequently, we examined the electrophysiological studies that support the diverse roles of cck-2 receptor activation in neocortical and hippocampal synaptic plasticity, and discussed the potential mechanisms that may be involved. |
2022-11-14 |
2023-08-14 |
Not clear |
| Siu Hin Lau, Ching Han Young, Yilin Zheng, Xi Che. The potential role of the cholecystokinin system in declarative memory. Neurochemistry international. 2022-11-14. PMID:36375634. |
last but not least, we discussed whether the reported cck-mediated synaptic plasticity can explain the strong influence of the cck signaling system in neocortex and hippocampus dependent declarative memory. |
2022-11-14 |
2023-08-14 |
Not clear |
| Siu Hin Lau, Ching Han Young, Yilin Zheng, Xi Che. The potential role of the cholecystokinin system in declarative memory. Neurochemistry international. 2022-11-14. PMID:36375634. |
although a direct link between cck-mediated synaptic plasticity and hippocampus dependent declarative memory is missing, noticeable evidence from morphological, behavioral, and electrophysiological studies encourages further investigation regarding the potential role of cck-dependent synaptic plasticity in hippocampus dependent declarative memory. |
2022-11-14 |
2023-08-14 |
Not clear |
| Hui Wang, Liang Liang, Can Yang, Ling Xiao, Huiling Wang, Gaohua Wang, Zhixian Zh. The protective role of hippocampal LRP1 knockdown involves synaptic plasticity through the promoting microtubule dynamics and activation of Akt/GSK-3β pathway in depressive rats. Journal of affective disorders. 2022-11-13. PMID:36372121. |
the protective role of hippocampal lrp1 knockdown involves synaptic plasticity through the promoting microtubule dynamics and activation of akt/gsk-3β pathway in depressive rats. |
2022-11-13 |
2023-08-14 |
rat |
| Hardy Hagena, Denise Manahan-Vaugha. Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience. Cells. vol 11. issue 21. 2022-11-11. PMID:36359749. |
role of mglu5 in persistent forms of hippocampal synaptic plasticity and the encoding of spatial experience. |
2022-11-11 |
2023-08-14 |
Not clear |
| Hardy Hagena, Denise Manahan-Vaugha. Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience. Cells. vol 11. issue 21. 2022-11-11. PMID:36359749. |
of these, mglu5 has emerged as a key factor in the induction and maintenance of persistent (>24 h) forms of hippocampal synaptic plasticity. |
2022-11-11 |
2023-08-14 |
Not clear |
| Hardy Hagena, Denise Manahan-Vaugha. Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience. Cells. vol 11. issue 21. 2022-11-11. PMID:36359749. |
in this review article we shall address the state of the art in terms of the role of mglu5 in forms of hippocampal synaptic plasticity related to experience-dependent information storage and present evidence that normal mglu5 function is central to these processes. |
2022-11-11 |
2023-08-14 |
Not clear |
| Tatyana Y Postnikova, Alina M Trofimova, Maria V Zakharova, Olga I Nosova, Alexey R Brazhe, Dmitry E Korzhevskii, Alexey V Semyanov, Aleksey V Zaitse. Delayed Impairment of Hippocampal Synaptic Plasticity after Pentylenetetrazole-Induced Seizures in Young Rats. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362260. |
delayed impairment of hippocampal synaptic plasticity after pentylenetetrazole-induced seizures in young rats. |
2022-11-11 |
2023-08-14 |
rat |
| Nikita Zernov, Alexander V Veselovsky, Vladimir V Poroikov, Daria Melentieva, Anastasia Bolshakova, Elena Popugaev. New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362339. |
we demonstrate that it binds to the extracellular agonist binding site of the human trpc6, protects hippocampal mushroom spines from amyloid toxicity in vitro, efficiently recovers synaptic plasticity in 5xfad brain slices, penetrates the blood-brain barrier and recovers cognitive deficits in 5xfad mice. |
2022-11-11 |
2023-08-14 |
mouse |
| Shirin Hosseini, Marco van Ham, Christian Erck, Martin Korte, Kristin Michaelsen-Preuss. The role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons. Frontiers in molecular neuroscience. vol 15. 2022-11-07. PMID:36340693. |
ttl loss was also associated with a deficit in spatial learning, impaired synaptic plasticity, and reduced number of spines in hippocampal neurons, suggesting that ttl also plays a critical role in hippocampal network development. |
2022-11-07 |
2023-08-14 |
mouse |