Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Nataya Sritawan, Apiwat Sirichoat, Anusara Aranarochana, Wanassanan Pannangrong, Peter Wigmore, Jariya Umka Welba. Protective effect of metformin on methotrexate induced reduction of rat hippocampal neural stem cells and neurogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 162. 2023-03-31. PMID:37001179. |
these consequences postulate that metformin has a potential to increase neural stem cells, synaptic plasticity, decreased apoptotic activities, and transcription factors, resulting in upregulation of hippocampal neurogenesis in mtx-treated rats. |
2023-03-31 |
2023-08-14 |
rat |
Alejandra Arias-Cavieres, Alfredo J Garci. A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance. bioRxiv : the preprint server for biology. 2023-03-30. PMID:36993632. |
a consequence of immature breathing induces persistent changes in hippocampal synaptic plasticity and behavior: a role of pro-oxidant state and nmda receptor imbalance. |
2023-03-30 |
2023-08-14 |
mouse |
Alejandra Arias-Cavieres, Alfredo J Garci. A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance. bioRxiv : the preprint server for biology. 2023-03-30. PMID:36993632. |
here, we investigated the impact of nih on hippocampal synaptic plasticity and nmda receptor (nmdar) expression in neonatal mice. |
2023-03-30 |
2023-08-14 |
mouse |
Macarena S Arrázola, Matías Lira, Felipe Véliz-Valverde, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo Cerpa, Thomas M Wishart, Felipe A Cour. Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation. Aging cell. 2023-03-28. PMID:36973898. |
finally, a quantitative proteomic analysis revealed that necroptosis inhibition leads to an overall improvement of the aged hippocampal proteome, including a subclass of molecular biofunctions associated with brain rejuvenation, such as long-term potentiation and synaptic plasticity. |
2023-03-28 |
2023-08-14 |
mouse |
Meng Cheng, Caihua Ye, Chunxiao Tian, Dongju Zhao, Haonan Li, Zuhao Sun, Yuyang Miao, Qiang Zhang, Junping Wang, Yan Do. Engineered macrophage-biomimetic versatile nanoantidotes for inflammation-targeted therapy against Alzheimer's disease by neurotoxin neutralization and immune recognition suppression. Bioactive materials. vol 26. 2023-03-23. PMID:36950153. |
benefiting from this two-pronged immunosuppressive strategy, ot-lipo@m exhibits outstanding therapeutic effects on ameliorating cognitive deficits, inhibiting neuronal apoptosis, and enhancing synaptic plasticity in ad mice, accompanied by the delayed hippocampal atrophy and brain microstructural disruption by |
2023-03-23 |
2023-08-14 |
mouse |
Luis A Márquez, Ernesto Griego, Carolina López Rubalcava, Emilio J Galvá. NMDA receptor activity during postnatal development determines intrinsic excitability and mossy fiber long-term potentiation of CA3 pyramidal cells. Hippocampus. 2023-03-20. PMID:36938755. |
our data demonstrate that transient hypofunction of nmdars impacts nmdar-independent forms of synaptic plasticity of the hippocampus. |
2023-03-20 |
2023-08-14 |
Not clear |
Antonio Figueiredo, Joseph F Chee. Endocannabinoid regulation of hippocampus-dependent memory. Experimental neurology. 2023-03-19. PMID:36934867. |
additionally, we examine the impact of cannabinoids on synaptic plasticity and intracellular signaling within the hippocampus related to these processes. |
2023-03-19 |
2023-08-14 |
Not clear |
Zi-Qian Cheng, Jie Fan, Fang-Yi Zhao, Jing-Yun Su, Qi-Han Sun, Ran-Ji Cui, Bing-Jin L. Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized mice. Neural regeneration research. vol 18. issue 9. 2023-03-17. PMID:36926734. |
these findings show that the antidepressant-like effects of 9-hour fasting may be related to the activation of the mammalian target of the rapamycin complex 1 signaling pathway and synaptic plasticity in the mammalian hippocampus. |
2023-03-17 |
2023-08-14 |
mouse |
Meysam Shekarian, Iraj Salehi, Safoura Raoufi, Masoumeh Asadbegi, Masoumeh Kourosh-Arami, Alireza Komak. Neuroprotective effects of vinpocetine, as a phosphodiesterase 1 inhibitor, on long-term potentiation in a rat model of Alzheimer's disease. BMC neuroscience. vol 24. issue 1. 2023-03-17. PMID:36927298. |
in this research, we investigated the neuroprotective and therapeutic effects of vin through hippocampal synaptic plasticity on a rat's model of alzheimer's disease (ad) induced by an intracerebroventricular (icv) injection of beta-amyloid (aβ). |
2023-03-17 |
2023-08-14 |
rat |
Tingting Gu, Chang Xu, Xiaozhou Meng, Dapeng Gao, Guanghao Jiang, Anqi Yin, Qingzhen Liu, Lidong Zhan. Sevoflurane Preconditioning Alleviates Posttraumatic Stress Disorder-Induced Apoptosis in the Hippocampus via the EZH2-Regulated Akt/mTOR Axis and Improves Synaptic Plasticity. Journal of molecular neuroscience : MN. 2023-03-17. PMID:36930428. |
sevoflurane preconditioning alleviates posttraumatic stress disorder-induced apoptosis in the hippocampus via the ezh2-regulated akt/mtor axis and improves synaptic plasticity. |
2023-03-17 |
2023-08-14 |
rat |
Judit Català-Solsona, Pablo J Lituma, Stefano Lutzu, Dolores Siedlecki-Wullich, Cristina Fábregas-Ordoñez, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Activity-dependent Nr4a2 induction modulates synaptic expression of AMPA receptors and plasticity via a Ca The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-03-17. PMID:36931707. |
the nuclear receptors subfamily 4 group a (nr4a) have emerged as possible modulators of hippocampal synaptic plasticity and cognitive functions. |
2023-03-17 |
2023-08-14 |
mouse |
Judit Català-Solsona, Pablo J Lituma, Stefano Lutzu, Dolores Siedlecki-Wullich, Cristina Fábregas-Ordoñez, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Activity-dependent Nr4a2 induction modulates synaptic expression of AMPA receptors and plasticity via a Ca The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-03-17. PMID:36931707. |
however, the molecular and cellular mechanisms underlying nr4a2-mediated hippocampal synaptic plasticity are not completely known. |
2023-03-17 |
2023-08-14 |
mouse |
Jing Yung Lai, Jian Xiang Ho, Audrey Siew Foong Kow, Gengfan Liang, Chau Ling Tham, Yu-Cheng Ho, Ming Tatt Le. Interferon therapy and its association with depressive disorders - A review. Frontiers in immunology. vol 14. 2023-03-13. PMID:36911685. |
reactive oxygen species (ros) is important for synaptic plasticity and long-term potentiation (ltp) in the hippocampus. |
2023-03-13 |
2023-08-14 |
Not clear |
Eunbi Cho, Se Jin Jeon, Jieun Jeon, Jee Hyun Yi, Huiyoung Kwon, Hyun-Ji Kwon, Kyoung Ja Kwon, Minho Moon, Chan Young Shin, Dong Hyun Ki. Phyllodulcin improves hippocampal long-term potentiation in 5XFAD mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 161. 2023-03-13. PMID:36913892. |
oral administration of phyllodulcin improved aβ-induced memory impairments in normal mice, reduced aβ deposition in the hippocampus, inhibited the activation of microglia and astrocytes, and improved synaptic plasticity in 5xfad mice. |
2023-03-13 |
2023-08-14 |
mouse |
Ji-Woon Kim, Kanzo Suzuki, Ege T Kavalali, Lisa M Monteggi. Bridging rapid and sustained antidepressant effects of ketamine. Trends in molecular medicine. 2023-03-12. PMID:36907686. |
ketamine blocks n-methyl-d-asparate (nmda) receptors (nmdars) to elicit specific downstream signaling that induces a novel form of synaptic plasticity in the hippocampus that has been linked to the rapid antidepressant action. |
2023-03-12 |
2023-08-14 |
Not clear |
Candice M Roux, Pierre Lecouflet, Jean-Marie Billard, Elise Esneault, Marianne Leger, Pascale Schumann-Bard, Thomas Frere. Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901735. |
genetic background influence on hippocampal synaptic plasticity: frequency-dependent variations between an inbred and an outbred mice strain. |
2023-03-11 |
2023-08-14 |
mouse |
Candice M Roux, Pierre Lecouflet, Jean-Marie Billard, Elise Esneault, Marianne Leger, Pascale Schumann-Bard, Thomas Frere. Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901735. |
in this paper, we discuss the anatomo-functional correlates that may explain such hippocampal synaptic plasticity divergence, although straightforward evidence is still lacking. |
2023-03-11 |
2023-08-14 |
mouse |
b' Loredana Raciti, Caterina Formica, Gianfranco Raciti, Angelo Quartarone, Rocco Salvatore Calabr\\xc3\\xb. Gender and Neurosteroids: Implications for Brain Function, Neuroplasticity and Rehabilitation. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902197.' |
neurosteroids could be considered the main players in both sexual steroid-induced hippocampal synaptic plasticity and normal transmission in the hippocampus. |
2023-03-11 |
2023-08-14 |
Not clear |
Yu-Fen Lin, Ching-An Chen, Fang-Yu Hsu, Ya-Hsin Hsia. Elevated Hippocampal CRMP5 Mediates Chronic Stress-Induced Cognitive Deficits by Disrupting Synaptic Plasticity, Hindering AMPAR Trafficking, and Triggering Cytokine Release. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902337. |
elevated hippocampal crmp5 mediates chronic stress-induced cognitive deficits by disrupting synaptic plasticity, hindering ampar trafficking, and triggering cytokine release. |
2023-03-11 |
2023-08-14 |
mouse |
Yu-Fen Lin, Ching-An Chen, Fang-Yu Hsu, Ya-Hsin Hsia. Elevated Hippocampal CRMP5 Mediates Chronic Stress-Induced Cognitive Deficits by Disrupting Synaptic Plasticity, Hindering AMPAR Trafficking, and Triggering Cytokine Release. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902337. |
our findings show that hippocampal crmp5 accumulation through gr activation disrupts synaptic plasticity, impedes ampar trafficking, and triggers cytokine release, thus playing a critical role in chronic stress-induced cognitive deficits. |
2023-03-11 |
2023-08-14 |
mouse |