| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjuan Zhou, Chen Zhang, Peipei Wang, Yuanying Deng, Hongmei Dai, Jing Tian, Guojiao Wu, Lingling Zha. Chlorpyrifos-induced dysregulation of synaptic plasticity in rat hippocampal neurons. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2023-02-01. PMID:36722685. |
this study aimed to investigate the effect of cpf on synaptic plasticity in hippocampal neurons and establish the cellular mechanism underlying these effects. |
2023-02-01 |
2023-08-14 |
rat |
| Wenjuan Zhou, Chen Zhang, Peipei Wang, Yuanying Deng, Hongmei Dai, Jing Tian, Guojiao Wu, Lingling Zha. Chlorpyrifos-induced dysregulation of synaptic plasticity in rat hippocampal neurons. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2023-02-01. PMID:36722685. |
our study suggests that cpf exposure induced dysregulation of synaptic plasticity in rat hippocampal neurons, which might provide novel information regarding the mechanism of cpf-induced neurodevelopmental disorders. |
2023-02-01 |
2023-08-14 |
rat |
| Sang Hun Lee, Vadim Y Bolshakov, Jie She. Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus. Molecular brain. vol 16. issue 1. 2023-01-30. PMID:36710361. |
presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus. |
2023-01-30 |
2023-08-14 |
mouse |
| Sang Hun Lee, Vadim Y Bolshakov, Jie She. Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus. Molecular brain. vol 16. issue 1. 2023-01-30. PMID:36710361. |
previous studies of ps function in the hippocampus demonstrated that loss of ps results in the impairment of short- and long-term synaptic plasticity and neurotransmitter release at hippocampal schaffer collateral (sc) and mossy fiber (mf) synapses. |
2023-01-30 |
2023-08-14 |
mouse |
| Zdenka Gasparova, Euridika Ruskova, Dominika Seckarova Michalikova, Zuzana Brnoliakova, Karol Svik, Lukas Slovak, Stefan Bezek, Vladimir Knezl, Ruzena Sotnikov. High-fructose intake-induced dyslipidemia and oxidative stress accompanied by hippocampal dysfunctions in hypertensive but not hypertriacylglycerolemic rats. General physiology and biophysics. vol 42. issue 1. 2023-01-27. PMID:36705302. |
further, in shr-f60 it increased serum triacylglycerols, tbars in the liver, a specific activity of naga in the kidney, aggravated glucose tolerance, deteriorated synaptic plasticity, and reduced somatic and dendritic responses in the hippocampus. |
2023-01-27 |
2023-08-14 |
rat |
| Iván Ballasch, Esther García-García, Cristina Vila, Anna Pérez-González, Anna Sancho-Balsells, Jéssica Fernández, David Soto, Mar Puigdellívol, Xavier Gasull, Jordi Alberch, Manuel J Rodríguez, Josep M Canals, Albert Giral. Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration. Brain, behavior, and immunity. 2023-01-26. PMID:36702234. |
altogether, these results suggest that altered ikzf1 levels in the adult hippocampus are sufficient to induce synaptic plasticity and memory deficits via altering microglial state and function. |
2023-01-26 |
2023-08-14 |
mouse |
| Jing Rong, Yang Yang, Min Liang, Haiquan Zhong, Yingchun Li, Yichao Zhu, Sha Sha, Lei Chen, Rong Zho. Neonatal inflammation increases hippocampal KCC2 expression through methylation-mediated TGF-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice. Journal of neuroinflammation. vol 20. issue 1. 2023-01-23. PMID:36691035. |
neonatal inflammation increases hippocampal kcc2 expression through methylation-mediated tgf-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice. |
2023-01-23 |
2023-08-14 |
mouse |
| Cátia R Lopes, Andreia Oliveira, Ingride Gaspar, Matilde S Rodrigues, Joana Santos, Eszter Szabó, Henrique B Silva, Ângelo R Tomé, Paula M Canas, Paula Agostinho, Rui A Carvalho, Rodrigo A Cunha, Ana Patrícia Simões, João Pedro Lopes, Samira G Ferreir. Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas. Biomolecules. vol 13. issue 1. 2023-01-21. PMID:36671491. |
we now report that male mice drinking caffeinated water (0.3 g/l) for 2 weeks were behaviorally indistinguishable (locomotion, mood, memory) from control mice (drinking water) and displayed superimposable synaptic plasticity (long-term potentiation) in different brain areas (hippocampus, prefrontal cortex, amygdala). |
2023-01-21 |
2023-08-14 |
mouse |
| Linlin Z Fan, Doo Kyung Kim, Joshua H Jennings, He Tian, Peter Y Wang, Charu Ramakrishnan, Sawyer Randles, Yanjun Sun, Elina Thadhani, Yoon Seok Kim, Sean Quirin, Lisa Giocomo, Adam E Cohen, Karl Deisserot. All-optical physiology resolves a synaptic basis for behavioral timescale plasticity. Cell. 2023-01-20. PMID:36669484. |
these results reveal synaptic implementation of hippocampal behavioral timescale plasticity and define a methodology to resolve synaptic plasticity during learning and memory in behaving mammals. |
2023-01-20 |
2023-08-14 |
mouse |
| Bo Zhang, Hang Li, Yan Wang, Yang Li, Zhongsheng Zhou, Xuejia Hou, Xiaowen Zhang, Te Li. Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats. Ecotoxicology and environmental safety. vol 251. 2023-01-18. PMID:36652739. |
lead can damage neuron synapses in the hippocampus and cause synaptic plasticity losses, and learning, memory, and intelligence impairments. |
2023-01-18 |
2023-08-14 |
rat |
| Huijie Zhang, Guangyin Yu, Jiong Li, Chunyi Tu, Yuqing Hui, Danlei Liu, Meiying Chen, Jifeng Zhang, Xiaobing Gong, Guoqing Gu. Overexpressing lnc240 Rescues Learning and Memory Dysfunction in Hepatic Encephalopathy Through miR-1264-5p/MEF2C Axis. Molecular neurobiology. 2023-01-16. PMID:36645630. |
lnc240 can regulate the expression of mef2c through mir-1264-5p and regulate the synaptic plasticity of hippocampal neurons, thereby saving the learning and memory dysfunction in he mice, suggesting that lnc240 might be a potential therapeutic target for the treatment of he. |
2023-01-16 |
2023-08-14 |
mouse |
| Xia Min, Jun-Ying Wang, Fang-Jiao Zong, Jing Zhao, Nan Liu, Kai-Wen H. miR-34a regulates silent synapse and synaptic plasticity in mature hippocampus. Progress in neurobiology. 2023-01-15. PMID:36642095. |
mir-34a regulates silent synapse and synaptic plasticity in mature hippocampus. |
2023-01-15 |
2023-08-14 |
mouse |
| Antonella Borreca, Mariassunta De Luca, Antonella Ferrante, Zaira Boussadia, Annabella Pignataro, Alberto Martire, Martine Ammassari-Teul. Fmr1-KO mice failure to detect object novelty associates with a post-test decrease of structural and synaptic plasticity upstream of the hippocampus. Scientific reports. vol 13. issue 1. 2023-01-14. PMID:36641518. |
fmr1-ko mice failure to detect object novelty associates with a post-test decrease of structural and synaptic plasticity upstream of the hippocampus. |
2023-01-14 |
2023-08-14 |
mouse |
| Yoon Ji Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yan. Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices. STAR protocols. vol 4. issue 1. 2023-01-12. PMID:36633949. |
we detail the steps for (1) obtaining acute mouse hippocampal slices that contain longitudinal dg-dg connections, (2) measuring excitatory postsynaptic potentials using whole-cell patch clamp recording combined with two-photon microscopy and glutamate uncaging, and (3) assessing synaptic plasticity using extracellular field recording. |
2023-01-12 |
2023-08-14 |
mouse |
| Emily Nicole Walsh, Mahesh Shivarama Shetty, Kamran Diba, Ted Abe. Chemogenetic enhancement of cAMP signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation. eNeuro. 2023-01-12. PMID:36635248. |
chemogenetic enhancement of camp signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation. |
2023-01-12 |
2023-08-14 |
Not clear |
| Hye-Hyun Kim, Suk-Ho Lee, Won-Kyung Ho, Kisang Eo. Dopamine Receptor Supports the Potentiation of Intrinsic Excitability and Synaptic LTD in Temporoammonic-CA1 Synapse. Experimental neurobiology. vol 31. issue 6. 2023-01-11. PMID:36631845. |
hence, the dopaminergic modulation of synaptic plasticity in the hippocampus has been widely studied. |
2023-01-11 |
2023-08-14 |
Not clear |
| Victoria T Ethridge, Nathan M Gargas, Martha J Sonner, Raquel J Moore, Shannon H Romer, Candice Hatcher-Solis, Joyce G Roha. Effects of transcranial direct current stimulation on brain cytokine levels in rats. Frontiers in neuroscience. vol 16. 2023-01-09. PMID:36620466. |
we previously showed that 30 min of 0.25 ma tdcs administered to rats induced significant enhancement in the synaptic plasticity of hippocampal neurons. |
2023-01-09 |
2023-08-14 |
rat |
| Huiya Ying, Zilong Zhang, Wei Wang, Zijing Yang, Cancan You, Yuanai Li, Xiaohong Cai, Xiucui L. Inhibition of Calcium-Sensing Receptor Alleviates Chronic Intermittent Hypoxia-Induced Cognitive Dysfunction via CaSR-PKC-ERK1/2 Pathway. Molecular neurobiology. 2023-01-04. PMID:36600080. |
cih accelerated apoptosis of hippocampal neurons and resulted in the synaptic plasticity deficit via downregulated synaptophysin (syn) protein level. |
2023-01-04 |
2023-08-14 |
mouse |
| Huiya Ying, Zilong Zhang, Wei Wang, Zijing Yang, Cancan You, Yuanai Li, Xiaohong Cai, Xiucui L. Inhibition of Calcium-Sensing Receptor Alleviates Chronic Intermittent Hypoxia-Induced Cognitive Dysfunction via CaSR-PKC-ERK1/2 Pathway. Molecular neurobiology. 2023-01-04. PMID:36600080. |
the mice were intraperitoneally injected with casr inhibitor (nps2143) 30 min before cih exposure and the results demonstrated casr inhibitor alleviated the apoptosis and synaptic plasticity deficit in the hippocampus of cih mice. |
2023-01-04 |
2023-08-14 |
mouse |
| Huiya Ying, Zilong Zhang, Wei Wang, Zijing Yang, Cancan You, Yuanai Li, Xiaohong Cai, Xiucui L. Inhibition of Calcium-Sensing Receptor Alleviates Chronic Intermittent Hypoxia-Induced Cognitive Dysfunction via CaSR-PKC-ERK1/2 Pathway. Molecular neurobiology. 2023-01-04. PMID:36600080. |
overall, our findings revealed that casr held a critical function on cih-induced cognitive dysfunction in mice by accelerating hippocampal neuronal apoptosis and reducing synaptic plasticity via augmenting casr-pkc-erk1/2 pathway; otherwise, inhibition of casr alleviated cih-induced cognitive dysfunction. |
2023-01-04 |
2023-08-14 |
mouse |