| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mario Díaz, Daniel Pereda de Pablo, Catalina Valdés-Baizabal, Guido Santos, Raquel Mari. Molecular and biophysical features of hippocampal "lipid rafts aging" are modified by dietary n-3 long-chain polyunsaturated fatty acids. Aging cell. 2023-05-31. PMID:37254617. |
unexpectedly, this diet also modified the lipidome and dimension of lipid rafts, as well as the domain redistribution of glutamate receptors and acid-sensing ion channels involved in hippocampal synaptic plasticity, likely modulating functionality of lipid rafts in memory formation and reluctance to age-associated cognitive decline. |
2023-05-31 |
2023-08-14 |
mouse |
| Suhel Parvez, Binu Ramachandran, Medha Kaushik, Heena Tabassum, Julietta U Fre. Long-term depression induction and maintenance across regions of the apical branch of CA1 dendrites. Hippocampus. 2023-05-31. PMID:37254828. |
well known as the center for learning and memory, hippocampus is the crucial brain region to study synaptic plasticity in the context of cellular fundamental mechanisms such as long-term depression (ltd) and long-term potentiation (ltp). |
2023-05-31 |
2023-08-14 |
rat |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
in this study, a novel cck analogue was synthesized on the basis of preserving the minimum bioactive fragment of endogenous cck to investigate whether the novel cck analogue could improve synaptic plasticity in the hippocampus of the app/ps1 transgenic mouse model of ad and its possible molecular biological mechanism. |
2023-05-29 |
2023-08-14 |
mouse |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
our study found that the cck analogue could effectively improve spatial learning and memory, enhance synaptic plasticity in the hippocampus, normalize synapse numbers and morphology and the levels of key synaptic proteins, up-regulate the pi3k/akt signaling pathway and normalize pka, creb, bdnf and trkb receptor levels in app/ps1 mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Ga-Young Choi, Hyun-Bum Kim, Jae-Min Cho, Inturu Sreelatha, In-Seo Lee, Hee-Seok Kweon, Sehyun Sul, Sun Ae Kim, Sungho Maeng, Ji-Ho Par. Umbelliferone Ameliorates Memory Impairment and Enhances Hippocampal Synaptic Plasticity in Scopolamine-Induced Rat Model. Nutrients. vol 15. issue 10. 2023-05-27. PMID:37242234. |
umbelliferone ameliorates memory impairment and enhances hippocampal synaptic plasticity in scopolamine-induced rat model. |
2023-05-27 |
2023-08-14 |
rat |
| Yaling Fu, Xiangfei Guo, Rui Yang, Hao Feng, Xueyong Yin, Shuang Wang, Li Song, Xi Wang, Penghui Zhao, Sheng Wang, Yun Shi, Haishui Sh. Hippocampal BAIAP2 prevents chronic mild stress-induced depression-like behaviors in mice. Frontiers in psychiatry. vol 14. 2023-05-26. PMID:37234209. |
the pathogenesis of depression is closely related to changes in hippocampal synaptic plasticity; however, the underlying mechanism is still unclear. |
2023-05-26 |
2023-08-14 |
mouse |
| Yaling Fu, Xiangfei Guo, Rui Yang, Hao Feng, Xueyong Yin, Shuang Wang, Li Song, Xi Wang, Penghui Zhao, Sheng Wang, Yun Shi, Haishui Sh. Hippocampal BAIAP2 prevents chronic mild stress-induced depression-like behaviors in mice. Frontiers in psychiatry. vol 14. 2023-05-26. PMID:37234209. |
brain-specific angiogenesis inhibitor 1-associated protein 2 (baiap2), a postsynaptic scaffold protein in excitatory synapses important for synaptic plasticity, is highly expressed in the hippocampus and has been implicated in several psychiatric disorders. |
2023-05-26 |
2023-08-14 |
mouse |
| Erik D Nelson, Kristen R Maynard, Kyndall R Nicholas, Matthew N Tran, Heena R Divecha, Leonardo Collado-Torres, Stephanie C Hicks, Keri Martinowic. Activity-regulated gene expression across cell types of the mouse hippocampus. Hippocampus. 2023-05-25. PMID:37226416. |
activity-regulated gene (arg) expression patterns in the hippocampus (hpc) regulate synaptic plasticity, learning, and memory, and are linked to both risk and treatment responses for many neuropsychiatric disorders. |
2023-05-25 |
2023-08-14 |
mouse |
| Bakhtiarzadeh Fatemeh, Shahpasand Koorosh, Shojaei Amir, Fathollahi Yaghoub, Mirnajafi-Zadeh Java. Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice. Behavioral and brain functions : BBF. vol 19. issue 1. 2023-05-25. PMID:37231523. |
the present study investigated the long-term effects of tauopathy on learning and memory, synaptic plasticity, and hippocampal cell numbers. |
2023-05-25 |
2023-08-14 |
mouse |
| Miriam S Nokia, Tomi Waselius, Markku Penttone. CA3-CA1 long-term potentiation occurs regardless of respiration and cardiac cycle phases in urethane-anesthetized rats. Hippocampus. 2023-05-24. PMID:37221699. |
in the future, the effect of cardiorespiratory rhythms on synaptic plasticity could also be studied in awake state and in other parts of the hippocampal tri-synaptic loop. |
2023-05-24 |
2023-08-14 |
rat |
| Yoonsub Kim, Sooyun Kim, Won-Kyung Ho, Suk-Ho Le. Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses. Molecular brain. vol 16. issue 1. 2023-05-22. PMID:37217996. |
the physiological significance of burst firings of hippocampal dentate gcs in synaptic plasticity remains unknown. |
2023-05-22 |
2023-08-14 |
Not clear |
| Chanho Kong, Ji Woong Ahn, Sohyun Kim, Ji Young Park, Young Cheol Na, Jin Woo Chang, Seungsoo Chung, Won Seok Chan. Long-lasting restoration of memory function and hippocampal synaptic plasticity by focused ultrasound in Alzheimer's disease. Brain stimulation. 2023-05-21. PMID:37211337. |
long-lasting restoration of memory function and hippocampal synaptic plasticity by focused ultrasound in alzheimer's disease. |
2023-05-21 |
2023-08-14 |
Not clear |
| Ziwen An, Jing Yang, Fang Xiao, Junli Lv, Xiaoqing Xing, Heqiong Liu, Lei Wang, Yi Liu, Zhanchi Zhang, Huicai Gu. Hippocampal Proteomics Reveals the Role of Glutamatergic Synapse Activation in the Depression Induced by Perfluorooctane Sulfonate. Journal of agricultural and food chemistry. 2023-05-16. PMID:37191230. |
our results highlight that pfos exposure may inhibit the synaptic plasticity of the hippocampus via glutamatergic synapse and the creb/bdnf signaling pathway to cause depressive-like behaviors in male mice. |
2023-05-16 |
2023-08-14 |
mouse |
| Daniela Madeira, Cátia R Lopes, Ana P Simões, Paula M Canas, Rodrigo A Cunha, Paula Agostinh. Astrocytic A Glia. 2023-05-15. PMID:37183905. |
astrocytic a astrocytes are wired to bidirectionally communicate with neurons namely with synapses, thus shaping synaptic plasticity, which in the hippocampus is considered to underlie learning and memory. |
2023-05-15 |
2023-08-14 |
Not clear |
| Carmen Vivar, Ben Peterson, Alejandro Pinto, Emma Janke, Henriette van Praa. Running throughout middle-age keeps eNeuro. 2023-05-15. PMID:37188520. |
in rodents, running increases the number of adult-born neurons in the dentate gyrus (dg) of the hippocampus, in association with improved synaptic plasticity and memory function. |
2023-05-15 |
2023-08-14 |
mouse |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
in this study, the effect of treadmill exercise on hippocampal synaptic plasticity was evaluated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced chronic pd models. |
2023-05-14 |
2023-08-14 |
mouse |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
the direct protective effect of fndc5 is achieved by promoting the secretion of bdnf in the hippocampal neurons via binding the integrin αvβ5 receptor, thereby improving synaptic plasticity. |
2023-05-14 |
2023-08-14 |
mouse |
| Jing Wang, Jianxing Wang, Yulai Wang, Yiwen Chai, Haochen Li, Deyang Miao, Honggui Liu, Jianhong Li, Jun Ba. Music with Different Tones Affects the Development of Brain Nerves in Mice in Early Life through BDNF and Its Downstream Pathways. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175826. |
in addition, the number of dendritic spines and the number of dendritic spines per unit length were significantly higher than those in group c, and the expressions of synaptic plasticity proteins (syp and psd95) were also significantly elevated over those in group c. compared with group c, the expression levels of bdnf, trkb, creb, pi3k, akt, gs3kβ, plcγ1, pkc, dag, erk and mapk genes and proteins in the hippocampus and prefrontal cortex of mice in the music groups were up-regulated, suggesting that different tones of music could regulate neural development through bdnf and its downstream pathways. |
2023-05-14 |
2023-08-14 |
mouse |
| Alexander Maltsev, Sergei Funikov, Alexander Rezvykh, Ekaterina Teterina, Vladimir Nebogatikov, Alexander Burov, Natalia Bal, Aleksey Ustyugov, Vadim Karpov, Alexey Morozo. Chronic Administration of Non-Constitutive Proteasome Inhibitor Modulates Long-Term Potentiation and Glutamate Signaling-Related Gene Expression in Murine Hippocampus. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175876. |
here, to address the role of non-constitutive proteasomes in hippocampal synaptic plasticity and reveal the consequences of their continuous inhibition, we studied the effect of chronic administration of the non-constitutive proteasome inhibitor onx-0914 on the ltp induced by two different protocols: tetanic stimulation and theta-burst stimulation (tbs). |
2023-05-14 |
2023-08-14 |
Not clear |
| Fatemeh Zarei, Ahmad Ali Moazedi, Zahra Salimi, Ali Pourmotabbed, Namdar Yousofvand, Moradpour Farshad, Mohammad Reza Akram. Corrigendum to "Activation of androgen receptors alters hippocampal synaptic plasticity and memory retention through modulation of L-type calcium channels" [Life Sci. 314 (2023) 121155]. Life sciences. 2023-05-10. PMID:37164836. |
corrigendum to "activation of androgen receptors alters hippocampal synaptic plasticity and memory retention through modulation of l-type calcium channels" [life sci. |
2023-05-10 |
2023-08-14 |
Not clear |