| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinxin Gu, Lixue Chen, Ran Sun, Jie-Li Wang, Juntao Wang, Yingjun Lin, Shuwen Lei, Yang Zhang, Dan Lv, Faqin Jiang, Yuru Deng, James P Collman, Lei F. Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice. Frontiers in molecular biosciences. vol 9. 2022-03-14. PMID:35281262. |
further rna-sequencing, immunoblotting and immunofluorescence analyses confirmed that plasmalogens remarkably enhanced both the synaptic plasticity and neurogenesis in aged murine hippocampus. |
2022-03-14 |
2023-08-13 |
mouse |
| Segewkal H Heruye, Ted J Warren, Joseph A Kostansek Iv, Samantha B Draves, Stephanie A Matthews, Peter J West, Kristina A Simeone, Timothy A Simeon. Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices. Nutrients. vol 14. issue 3. 2022-03-12. PMID:35276972. |
ascorbic acid reduces neurotransmission, synaptic plasticity, and spontaneous hippocampal rhythms in in vitro slices. |
2022-03-12 |
2023-08-13 |
mouse |
| Yee Song Chong, Lik-Wei Wong, Jessica Gaunt, Yan Jun Lee, Cai Shan Goh, Richard G M Morris, Toh Hean Ch'ng, Sreedharan Sajikuma. Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity. Cerebral cortex (New York, N.Y. : 1991). 2022-03-07. PMID:35253866. |
the amygdala is known to modulate hippocampal synaptic plasticity. |
2022-03-07 |
2023-08-13 |
Not clear |
| Yee Song Chong, Lik-Wei Wong, Jessica Gaunt, Yan Jun Lee, Cai Shan Goh, Richard G M Morris, Toh Hean Ch'ng, Sreedharan Sajikuma. Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity. Cerebral cortex (New York, N.Y. : 1991). 2022-03-07. PMID:35253866. |
one role could be an immediate effect of basolateral amygdala (bla) in priming synaptic plasticity in the hippocampus. |
2022-03-07 |
2023-08-13 |
Not clear |
| Maxence Cornille, Stéphanie Moriceau, Roman H Khonsari, Yann Heuzé, Léa Loisay, Valérie Boitez, Anne Morice, Eric Arnaud, Corinne Collet, Morad Bensidhoum, Nabil Kaci, Nathalie Boddaert, Giovanna Paternoster, Theresa Rauschendorfer, Sabine Werner, Suzanne L Mansour, Federico Di Rocco, Franck Oury, Laurence Legeai-Malle. FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model. The Journal of experimental medicine. vol 219. issue 4. 2022-03-07. PMID:35254402. |
surprisingly, fgfr3a385e/+ mice did not exhibit craniosynostosis but did show severe memory impairments, a structurally abnormal hippocampus, low activity-dependent synaptic plasticity, and overactivation of mapk/erk and akt signaling pathways in the hippocampus. |
2022-03-07 |
2023-08-13 |
mouse |
| Yasunori Takahashi, Hiromu Okano, Kazumi Takashima, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Oral exposure to high-dose ethanol for 28 days in rats reduces neural stem cells and immediate nascent neural progenitor cells as well as FOS-expressing newborn granule cells in adult hippocampal neurogenesis. Toxicology letters. 2022-03-01. PMID:35227807. |
in rats, developmental exposure to ethanol (etoh) at high doses has shown to induce aberrant neurogenesis in neural progenitor cells (npcs) during weaning and suppress synaptic plasticity of newborn granule cells after maturation; neuroinflammation was even sustained until the adult stage in the hippocampal dentate gyrus (dg). |
2022-03-01 |
2023-08-13 |
rat |
| Wenjuan Wang, Caiyun Deng, Fang Chen, Li Zhang, Yi Hu, Qin Lu, Aihua Zhan. Resveratrol attenuates methylmercury-induced neurotoxicity by modulating synaptic homeostasis. Toxicology and applied pharmacology. 2022-03-01. PMID:35231462. |
at the same time, rsv ameliorated the perinatal mehg exposure-induced impairments in synaptic plasticity, spinal-related pathways and learning memory capacity in pups, as well as the pathological changes in the hippocampus. |
2022-03-01 |
2023-08-13 |
Not clear |
| Bin Wang, Xuewei Yang, Jincheng Lu, Michael Ntim, Min Xia, Supratik Kundu, Rong Jiang, Defang Chen, Ying Wang, Jin-Yi Yang, Shao L. Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice. Experimental neurology. 2022-02-26. PMID:35218707. |
the 2 h-ars but not 3.5 h-ars enhances synaptic plasticity and genes transcription associated with learning and memory in the hippocampus of male mice. |
2022-02-26 |
2023-08-13 |
mouse |
| Ji-Woong Ahn, Sohyun Kim, Sukjin Ko, Young-Hwan Kim, Ji-Hyun Jeong, Seungsoo Chun. Modified (-)-gallocatechin gallate-enriched green tea extract rescues age-related cognitive deficits by restoring hippocampal synaptic plasticity. Biochemistry and biophysics reports. vol 29. 2022-02-24. PMID:35198737. |
modified (-)-gallocatechin gallate-enriched green tea extract rescues age-related cognitive deficits by restoring hippocampal synaptic plasticity. |
2022-02-24 |
2023-08-13 |
Not clear |
| Xiaoyan Zhao, Dongjing Shi, Yingjie Du, Chunhua Hu, Yun Li, Jinsheng Liu, Chuxiong Pa. Repeated neonatal exposure to sevoflurane induces age-dependent impairments in cognition and synaptic plasticity in mice. Developmental neuroscience. 2022-02-24. PMID:35203077. |
theta burst stimulation-induced long-term potentiation (ltp) was measured in acute hippocampal slices from p38 and p68 mice to assess the synaptic plasticity. |
2022-02-24 |
2023-08-13 |
mouse |
| Lucas Taoro-González, Andrea Cabrera-Pastor, María Sancho-Alonso, Vicente Felip. Intracellular and extracelluar cyclic GMP in the brain and the hippocampus. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180929. |
and brain (hippocampal synaptic plasticity, neuroinflammation, cognitive function, etc.) |
2022-02-19 |
2023-08-13 |
rat |
| Lucas Taoro-González, Andrea Cabrera-Pastor, María Sancho-Alonso, Vicente Felip. Intracellular and extracelluar cyclic GMP in the brain and the hippocampus. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180929. |
the role of extracellular cgmp has been specially studied in hippocampal function and cognitive impairment in animal models and it has emerged as an important modulator of neuroinflammation-mediated cognitive alterations and hippocampal synaptic plasticity malfunction. |
2022-02-19 |
2023-08-13 |
rat |
| Mahmoud Elahdadi Salmani, Masoumeh Sarfi, Iran Goudarz. Hippocampal orexin receptors: Localization and function. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180935. |
briefly, we will review the localization and functions of hippocampal orexin receptors, their role in learning, memory, stress, reward, seizures, epilepsy, and hippocampal synaptic plasticity. |
2022-02-19 |
2023-08-13 |
Not clear |
| Ana-Maria Zagrean, Ioana-Antoaneta Georgescu, Mara Ioana Iesanu, Rosana-Bristena Ionescu, Robert Mihai Haret, Anca Maria Panaitescu, Leon Zagrea. Oxytocin and vasopressin in the hippocampus. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180939. |
oxt and avp have important roles in the hippocampus, by modulating important processes like neuronal excitability, network oscillatory activity, synaptic plasticity, and social recognition memory. |
2022-02-19 |
2023-08-13 |
Not clear |
| Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zho. APT1-mediated de-palmitoylation regulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-15. PMID:35165175. |
apt1-mediated de-palmitoylation regulates hippocampal synaptic plasticity. |
2022-02-15 |
2023-08-13 |
rat |
| Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zho. APT1-mediated de-palmitoylation regulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-15. PMID:35165175. |
herein, we employed acyl-biotin exchange, co-immunoprecipitation and biotinylation assays, and behavioral and electrophysiological methods, to explore whether palmitoylation is required for hippocampal synaptic transmission and fear memory formation, and involved in functional modification of synaptic proteins such as psd-95 and glutamate receptors, and detected if de-palmitoylation by specific enzymes has influence on glutamatergic synaptic plasticity. |
2022-02-15 |
2023-08-13 |
rat |
| Yeseul Lee, Zuner A Bortolotto, Clarrisa A Bradley, Thomas M Sanderson, Min Zhuo, Bong-Kiun Kaang, Graham L Collingridg. The GSK-3 Inhibitor CT99021 Enhances the Acquisition of Spatial Learning and the Accuracy of Spatial Memory. Frontiers in molecular neuroscience. vol 14. 2022-02-14. PMID:35153671. |
previously, we reported that inhibition of gsk-3 prevents the induction of one of the major forms of synaptic plasticity, n-methyl-d-aspartate receptor (nmdar)-dependent long-term depression (ltd), in hippocampal slices. |
2022-02-14 |
2023-08-13 |
mouse |
| Vahid Sheibani, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Elham Haghparast, Masoumeh Nozari, Saeed Esmaeili-Mahani, Akram Nezhad. The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study. Neuropeptides. vol 92. 2022-02-14. PMID:35158223. |
the dopaminergic system is a powerful candidate targeted for changes of synaptic plasticity in the hippocampus. |
2022-02-14 |
2023-08-13 |
rat |
| Vahid Sheibani, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Elham Haghparast, Masoumeh Nozari, Saeed Esmaeili-Mahani, Akram Nezhad. The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study. Neuropeptides. vol 92. 2022-02-14. PMID:35158223. |
these findings showed that partial dopamine depletion led to unusual synaptic plasticity in the ca1 as well as the decrease in synaptic proteins in the hippocampus. |
2022-02-14 |
2023-08-13 |
rat |
| Ana Belén Sanz-Martos, Jesús Fernández-Felipe, Beatriz Merino, Victoria Cano, Mariano Ruiz-Gayo, Nuria Del Olm. The Butyric Acid Precursor Tributyrin Modulates Hippocampal Synaptic Plasticity And Prevents Spatial Memory Deficits: Role Of PPARγ And AMPK. The international journal of neuropsychopharmacology. 2022-02-13. PMID:35152284. |
the butyric acid precursor tributyrin modulates hippocampal synaptic plasticity and prevents spatial memory deficits: role of pparγ and ampk. |
2022-02-13 |
2023-08-13 |
Not clear |