All Relations between reward and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Erin C Hanlon, Ruth M Benca, Brian A Baldo, Ann E Kelle. REM sleep deprivation produces a motivational deficit for food reward that is reversed by intra-accumbens amphetamine in rats. Brain research bulletin. vol 83. issue 5. 2011-02-23. PMID:20619322. these data suggest that decreased motivation for food reward caused by remsd may result from a suppression of dopamine function in the acb. 2011-02-23 2023-08-12 rat
Mitchell F Roitman, Robert A Wheeler, Paul H E Tiesinga, Jamie D Roitman, Regina M Carell. Hedonic and nucleus accumbens neural responses to a natural reward are regulated by aversive conditioning. Learning & memory (Cold Spring Harbor, N.Y.). vol 17. issue 11. 2011-02-11. PMID:20971936. hedonic and nucleus accumbens neural responses to a natural reward are regulated by aversive conditioning. 2011-02-11 2023-08-12 rat
K K Pitchers, K S Frohmader, V Vialou, E Mouzon, E J Nestler, M N Lehman, L M Coole. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20618447. Δfosb in the nucleus accumbens is critical for reinforcing effects of sexual reward. 2011-02-08 2023-08-12 rat
Mark C Moffett, Jane Song, Michael J Kuha. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506412. previously, our laboratory demonstrated that injections of cart peptide (cart 55-102) into the nucleus accumbens (nac) attenuated both cocaine- and dopamine-induced increases in locomotor activity (lma), and attenuated cocaine reward as well. 2011-02-04 2023-08-12 rat
Sean B Ostlund, Kate M Wassum, Niall P Murphy, Bernard W Balleine, Nigel T Maidmen. Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 1. 2011-02-04. PMID:21209205. the current study used microdialysis to monitor changes in extracellular da levels across subregions of the nucleus accumbens and dorsal striatum of rats as they lever pressed for food reward on a probabilistic schedule of reinforcement, a procedure that ensured they would experience variation in the amount of effort needed to earn rewards across tests. 2011-02-04 2023-08-12 rat
Moritz de Greck, Björn Enzi, Ulrike Prösch, Ana Gantman, Claus Tempelmann, Georg Northof. Decreased neuronal activity in reward circuitry of pathological gamblers during processing of personal relevant stimuli. Human brain mapping. vol 31. issue 11. 2011-01-28. PMID:20162606. pathological gamblers revealed diminished deactivation during monetary loss events in some of our core reward regions, the left nucleus accumbens and the left putamen. 2011-01-28 2023-08-12 Not clear
Moritz de Greck, Björn Enzi, Ulrike Prösch, Ana Gantman, Claus Tempelmann, Georg Northof. Decreased neuronal activity in reward circuitry of pathological gamblers during processing of personal relevant stimuli. Human brain mapping. vol 31. issue 11. 2011-01-28. PMID:20162606. moreover, while pathological gamblers viewed stimuli of high personal relevance, we found decreased neuronal activity in all of our core reward regions, including the bilateral nucleus accumbens and the left ventral putamen cortex as compared to healthy controls. 2011-01-28 2023-08-12 Not clear
A C Shin, P J Pistell, C B Phifer, H R Berthou. Reversible suppression of food reward behavior by chronic mu-opioid receptor antagonism in the nucleus accumbens. Neuroscience. vol 170. issue 2. 2011-01-20. PMID:20654704. reversible suppression of food reward behavior by chronic mu-opioid receptor antagonism in the nucleus accumbens. 2011-01-20 2023-08-12 Not clear
Alexander Strobel, Jan Zimmermann, Anja Schmitz, Martin Reuter, Stefanie Lis, Sabine Windmann, Peter Kirsc. Beyond revenge: neural and genetic bases of altruistic punishment. NeuroImage. vol 54. issue 1. 2011-01-19. PMID:20673803. we report here that indeed, reward regions such as the nucleus accumbens showed punishment-related activation. 2011-01-19 2023-08-12 Not clear
George A Rogge, Li-Ling Shen, Michael J Kuha. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter. Brain research. vol 1344. 2011-01-10. PMID:20451507. both over expression of cyclic amp response element binding protein (creb) in the nucleus accumbens (nac), and intra-accumbal injection of cocaine- and amphetamine-regulated transcript (cart) peptides, have been shown to decrease cocaine reward. 2011-01-10 2023-08-12 rat
Saleem M Nicol. The flexible approach hypothesis: unification of effort and cue-responding hypotheses for the role of nucleus accumbens dopamine in the activation of reward-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 49. 2011-01-07. PMID:21147998. dopamine released in the nucleus accumbens is thought to contribute to the decision to exert effort to seek reward. 2011-01-07 2023-08-12 rat
J L Jones, J J Day, R A Wheeler, R M Carell. The basolateral amygdala differentially regulates conditioned neural responses within the nucleus accumbens core and shell. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20570714. given the importance of the nucleus accumbens (nac) and the basolateral amygdala (bla) in associative reward processes, recent research has examined the functional importance of bla-nac interactions. 2010-12-16 2023-08-12 Not clear
Vincent Vialou, Ian Maze, William Renthal, Quincey C LaPlant, Emily L Watts, Ezekiell Mouzon, Subroto Ghose, Carol A Tamminga, Eric J Nestle. Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980616. one molecule implicated in such adaptations is Δfosb, a transcription factor that accumulates in the rodent nucleus accumbens (nac), a key brain reward region, in response to either chronic stress or repeated exposure to drugs of abuse. 2010-11-30 2023-08-12 mouse
James M Bjork, Gang Chen, Ashley R Smith, Daniel W Homme. Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescents. Journal of child psychology and psychiatry, and allied disciplines. vol 51. issue 7. 2010-11-22. PMID:20025620. reward processing has been indexed by recruitment of incentive-motivational neurocircuitry of the ventral striatum (vs), including nucleus accumbens (nacc). 2010-11-22 2023-08-12 Not clear
Mary Kay Lobo, Herbert E Covington, Dipesh Chaudhury, Allyson K Friedman, HaoSheng Sun, Diane Damez-Werno, David M Dietz, Samir Zaman, Ja Wook Koo, Pamela J Kennedy, Ezekiell Mouzon, Murtaza Mogri, Rachael L Neve, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). vol 330. issue 6002. 2010-11-10. PMID:20947769. the nucleus accumbens is a key mediator of cocaine reward, but the distinct roles of the two subpopulations of nucleus accumbens projection neurons, those expressing dopamine d1 versus d2 receptors, are poorly understood. 2010-11-10 2023-08-12 Not clear
Mary Kay Lobo, Herbert E Covington, Dipesh Chaudhury, Allyson K Friedman, HaoSheng Sun, Diane Damez-Werno, David M Dietz, Samir Zaman, Ja Wook Koo, Pamela J Kennedy, Ezekiell Mouzon, Murtaza Mogri, Rachael L Neve, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). vol 330. issue 6002. 2010-11-10. PMID:20947769. because loss of trkb in d2+ neurons increases their neuronal excitability, we next used optogenetic tools to control selectively the firing rate of d1+ and d2+ nucleus accumbens neurons and studied consequent effects on cocaine reward. 2010-11-10 2023-08-12 Not clear
S M Gustin, P J Wrigley, P J Siddall, L A Henderso. Brain anatomy changes associated with persistent neuropathic pain following spinal cord injury. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 6. 2010-10-29. PMID:19815621. these anatomical changes were located in pain-related regions as well as regions of the classic reward circuitry, that is, the nucleus accumbens and orbitofrontal, dorsolateral prefrontal, and posterior parietal cortices. 2010-10-29 2023-08-12 human
Estela Camara, Antoni Rodriguez-Fornells, Thomas F Münt. Microstructural brain differences predict functional hemodynamic responses in a reward processing task. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 34. 2010-09-16. PMID:20739561. in this study, we show that white matter microstructure in the uncinate/inferior fronto-occipital fasciculus, defined by fractional anisotropy values derived from diffusion tensor magnetic resonance images, correlates with both short-term (indexed by the fmri blood oxygenation level-dependent response to reward in the nucleus accumbens) and long-term (indexed by the trait measure sensitivity to punishment) reactivity to rewards. 2010-09-16 2023-08-12 human
Estela Camara, Antoni Rodriguez-Fornells, Thomas F Münt. Microstructural brain differences predict functional hemodynamic responses in a reward processing task. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 34. 2010-09-16. PMID:20739561. moreover, trait measures of reward processing were also correlated with reward-related functional activation in the nucleus accumbens. 2010-09-16 2023-08-12 human
Matthew J Fuxjager, Robin M Forbes-Lorman, Dylan J Coss, Catherine J Auger, Anthony P Auger, Catherine A Marle. Winning territorial disputes selectively enhances androgen sensitivity in neural pathways related to motivation and social aggression. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 27. 2010-08-30. PMID:20616093. we also found that ar expression in brain regions that mediate motivation and reward, nucleus accumbens (nacc) and ventral tegmental area (vta), increases only in response to fights in the home territory. 2010-08-30 2023-08-12 mouse