| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z-X Xi, H K Kleitz, X Deng, B Ladenheim, X-Q Peng, X Li, E L Gardner, E A Stein, J L Cade. A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats. Neuroscience. vol 161. issue 2. 2009-08-19. PMID:19336247. |
the increased cocaine self-administration appeared to be a compensatory response to reduced cocaine reward after meth, because the same doses of meth caused a dose-dependent reduction both in "break-point" levels for cocaine self-administration under progressive-ratio reinforcement and in nucleus accumbens da response to acute cocaine. |
2009-08-19 |
2023-08-12 |
rat |
| Michael X Cohen, Nikolai Axmacher, Doris Lenartz, Christian E Elger, Volker Sturm, Thomas E Schlaepfe. Neuroelectric signatures of reward learning and decision-making in the human nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19092783. |
here, we show that the human nucleus accumbens plays a key role in learning about risks by representing reward value. |
2009-08-03 |
2023-08-12 |
human |
| Michael X Cohen, Nikolai Axmacher, Doris Lenartz, Christian E Elger, Volker Sturm, Thomas E Schlaepfe. Neuroelectric signatures of reward learning and decision-making in the human nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19092783. |
during the learning task, nucleus accumbens activity reflected potential and received reward values both during the cue stimulus and during the feedback. |
2009-08-03 |
2023-08-12 |
human |
| Matthew R Campioni, Ming Xu, Daniel S McGehe. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. Journal of neurophysiology. vol 101. issue 6. 2009-08-03. PMID:19357347. |
the nucleus accumbens (nac), a motor-limbic interface linked to motivation and reward, receives inputs from each of these stress-affected brain regions, raising the possibility that its function might also be altered in response to stress. |
2009-08-03 |
2023-08-12 |
mouse |
| Ke-chun Yang, Guo-zhang Jin, Jie W. Mysterious alpha6-containing nAChRs: function, pharmacology, and pathophysiology. Acta pharmacologica Sinica. vol 30. issue 6. 2009-07-31. PMID:19498417. |
by modulating da release in the nucleus accumbens (nac) and modulating gaba release onto daergic neurons in the ventral tegmental area (vta), alpha6*-nachrs may play important roles in the mediation of nicotine reward and addiction. |
2009-07-31 |
2023-08-12 |
mouse |
| Carl R Lupica, Arthur C Riege. Endocannabinoid release from midbrain dopamine neurons: a potential substrate for cannabinoid receptor antagonist treatment of addiction. Neuropharmacology. vol 48. issue 8. 2009-07-17. PMID:15878779. |
substantial evidence suggests that all commonly abused drugs act upon the brain reward circuitry to ultimately increase extracellular concentrations of the neurotransmitter dopamine in the nucleus accumbens and other forebrain areas. |
2009-07-17 |
2023-08-12 |
Not clear |
| Matthew B Wilkinson, Guanghua Xiao, Arvind Kumar, Quincey LaPlant, William Renthal, Devanjan Sikder, Thomas J Kodadek, Eric J Nestle. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 24. 2009-07-17. PMID:19535594. |
here, we use chromatin immunoprecipitation (chip)-chip assays--chip followed by genome wide promoter array analyses--to study the effects of chronic defeat stress on chromatin regulation in the mouse nucleus accumbens (nac), a key brain reward region implicated in depression. |
2009-07-17 |
2023-08-12 |
mouse |
| Beáta Sperlágh, Katalin Windisch, Rómeó D Andó, E Sylvester Viz. Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. Neurochemistry international. vol 54. issue 7. 2009-07-15. PMID:19428788. |
neurochemical evidence that stimulation of cb1 cannabinoid receptors on gabaergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. |
2009-07-15 |
2023-08-12 |
rat |
| A R Soderman, E M Unterwal. Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience. vol 154. issue 4. 2009-06-29. PMID:18550291. |
adult male sprague-dawley rats received injections of ctap into the caudate putamen, the rostral or caudal ventral tegmental area (vta) or the medial shell or core of the nucleus accumbens prior to cocaine to determine the role of mu opioid receptors in cocaine-induced reward and hyperactivity. |
2009-06-29 |
2023-08-12 |
rat |
| A R Soderman, E M Unterwal. Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience. vol 154. issue 4. 2009-06-29. PMID:18550291. |
these results demonstrate the importance of mu opioid receptors in the nucleus accumbens and vta in cocaine-induced reward and hyperactivity and suggest that some aspects of the behavioral effects of cocaine are mediated by endogenous activation of mu opioid receptors in these brain regions. |
2009-06-29 |
2023-08-12 |
rat |
| Michael X Cohen, Nikolai Axmacher, Doris Lenartz, Christian E Elger, Volker Sturm, Thomas E Schlaepfe. Good vibrations: cross-frequency coupling in the human nucleus accumbens during reward processing. Journal of cognitive neuroscience. vol 21. issue 5. 2009-06-04. PMID:18702577. |
good vibrations: cross-frequency coupling in the human nucleus accumbens during reward processing. |
2009-06-04 |
2023-08-12 |
human |
| Meena Vythilingam, Eric E Nelson, Matthew Scaramozza, Tracy Waldeck, Gary Hazlett, Steven M Southwick, Daniel S Pine, Wayne Drevets, Dennis S Charney, Monique Erns. Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers. Psychiatry research. vol 172. issue 1. 2009-05-29. PMID:19243926. |
findings in this group of resilient individuals revealed unique patterns of activation during expectation of reward in the subgenual prefrontal cortex and nucleus accumbens area, regions pivotal to reward processes. |
2009-05-29 |
2023-08-12 |
Not clear |
| Kacey Ballard, Brian Knutso. Dissociable neural representations of future reward magnitude and delay during temporal discounting. NeuroImage. vol 45. issue 1. 2009-04-28. PMID:19071223. |
combining a novel, temporally distributed discounting task with event-related fmri, we found that while nucleus accumbens (nacc), mesial prefrontal cortical (mpfc), and posterior cingulate cortical (pcc) activation positively correlated with future reward magnitude, dorsolateral prefrontal cortical (dlpfc) and posterior parietal cortical (ppc) activation negatively correlated with future reward delay. |
2009-04-28 |
2023-08-12 |
Not clear |
| Andreas Heinz, Anne Beck, Sabine M Grüsser, Anthony A Grace, Jana Wras. Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addiction biology. vol 14. issue 1. 2009-04-23. PMID:18855799. |
current brain imaging studies indicate that dysfunction of dopaminergic, glutamatergic and opioidergic neurotransmission in the brain reward system (ventral striatum including the nucleus accumbens) can be associated with alcohol craving and functional brain activation in neuronal systems that process attentional relevant stimuli, reward expectancy and experience. |
2009-04-23 |
2023-08-12 |
Not clear |
| William J Berglind, Timothy W Whitfield, Ryan T LaLumiere, Peter W Kalivas, Jacqueline F McGint. A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 12. 2009-04-21. PMID:19321768. |
the glutamatergic pathway arising in the dorsomedial prefrontal cortex (dmpfc) and projecting to the nucleus accumbens (nac) core is a critical component of the reward circuitry that underlies reinstatement to cocaine-seeking behavior. |
2009-04-21 |
2023-08-12 |
Not clear |
| George A Rogge, Douglas C Jones, Thomas Green, Eric Nestler, Michael J Kuha. Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain research. vol 1251. 2009-04-20. PMID:19046951. |
production of mrna from the cocaine- and amphetamine-regulated transcript (cart) gene is regulated by cocaine and other drugs of abuse in the nucleus accumbens (nac), a brain reward region. |
2009-04-20 |
2023-08-12 |
rat |
| William A Carlezon, Mark J Thoma. Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18675281. |
biological substrates of reward and aversion: a nucleus accumbens activity hypothesis. |
2009-04-15 |
2023-08-12 |
Not clear |
| William A Carlezon, Mark J Thoma. Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18675281. |
the nucleus accumbens (nac) is a critical element of the mesocorticolimbic system, a brain circuit implicated in reward and motivation. |
2009-04-15 |
2023-08-12 |
Not clear |
| Matthew M Botvinick, Stacy Huffstetler, Joseph T McGuir. Effort discounting in human nucleus accumbens. Cognitive, affective & behavioral neuroscience. vol 9. issue 1. 2009-04-07. PMID:19246324. |
we used fmri to measure neural responses to monetary rewards in the human nucleus accumbens (nacc), a structure previously demonstrated to encode reference-dependent reward information. |
2009-04-07 |
2023-08-12 |
human |
| Ulrich Kirk, Martin Skov, Mark Schram Christensen, Niels Nygaar. Brain correlates of aesthetic expertise: a parametric fMRI study. Brain and cognition. vol 69. issue 2. 2009-03-23. PMID:18783864. |
by contrast, activity in nucleus accumbens (nacc) exhibits a differential response profile compared to ofc and subcallosal cingulate gyrus, suggesting a dissociable role between these regions in the reward processing of expertise. |
2009-03-23 |
2023-08-12 |
Not clear |