All Relations between reward and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Stephanie R Ebner, Mitchell F Roitman, David N Potter, Anna B Rachlin, Elena H Chartof. Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. Psychopharmacology. vol 210. issue 2. 2010-08-17. PMID:20372879. although kor agonists decrease dopamine in the nucleus accumbens (nac), kor modulation of phasic dopamine release in the core and shell subregions of the nac-which have distinct roles in reward processing-remains poorly understood. 2010-08-17 2023-08-12 Not clear
A Lajtha, H Sershe. Heterogeneity of reward mechanisms. Neurochemical research. vol 35. issue 6. 2010-08-05. PMID:20012687. the finding that many drugs that have abuse potential and other natural stimuli such as food or sexual activity cause similar chemical changes in the brain, an increase in extracellular dopamine (da) in the shell of the nucleus accumbens (naccs), indicated some time ago that the reward mechanism is at least very similar for all stimuli and that the mechanism is relatively simple. 2010-08-05 2023-08-12 Not clear
Nesrin Filiz Basaran, R Levent Buyukuysal, William R Millington, Sinan Cavu. Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 381. issue 5. 2010-07-23. PMID:20349045. in this study, we tested the hypothesis that gly-gln inhibits morphine reward by blocking morphine-induced dopamine efflux in the nucleus accumbens (nac). 2010-07-23 2023-08-12 rat
Esther K Diekhof, Oliver Grube. When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107076. consistent with the view that the reward system interacts with prefrontal circuits during action control, we found that behavior favoring the long-term goal, but counteracting immediate reward desiring, relied on a negative functional interaction of anteroventral prefrontal cortex (avpfc) with nucleus accumbens (nacc) and ventral tegmental area. 2010-07-08 2023-08-12 human
N Zeeni, N Nadkarni, J D Bell, P C Even, G Fromentin, D Tome, N Darce. Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice. NeuroImage. vol 50. issue 4. 2010-06-23. PMID:20100582. assessment of brain response to cholecystokinin (cck) by manganese-enhanced mri (memri) showed a reduction in neuronal activity both in an appetite-related area (ventromedial nucleus of the hypothalamus) and areas associated with reward (nucleus accumbens and striatum) regardless of diet. 2010-06-23 2023-08-12 mouse
Irena Majkutewicz, Tomasz Cecot, Grazyna Jerzemowska, Dorota Myślińska, Karolina Plucińska, Weronika Trojniar, Danuta Wron. Lesion of the ventral tegmental area amplifies stimulation-induced Fos expression in the rat brain. Brain research. vol 1320. 2010-06-07. PMID:20079346. stimulation of the vta performed after contralateral lesion (l/s) evoked strong bilateral induction of fos expression in the mesolimbic structures involved in motivation and reward (nucleus accumbens and lateral septum) and the processing of the reinforcing properties of olfactory stimuli (anterior cortical amygdaloid nucleus) in parallel with facilitation of behavioral function measured as shortened latency of eating or exploration. 2010-06-07 2023-08-12 rat
Sonia Y Bernal, Khalid Touzani, Meri Gerges, Yana Abayev, Anthony Sclafani, Richard J Bodna. Opioid receptor antagonism in the nucleus accumbens fails to block the expression of sugar-conditioned flavor preferences in rats. Pharmacology, biochemistry, and behavior. vol 95. issue 1. 2010-06-01. PMID:20006967. because opioid signaling in the nucleus accumbens (nac) is implicated in food reward, this study determined if ntx administered into the nac would block the expression of sugar-conditioned preferences. 2010-06-01 2023-08-12 rat
Paul M Forlano, Catherine S Woolle. Quantitative analysis of pre- and postsynaptic sex differences in the nucleus accumbens. The Journal of comparative neurology. vol 518. issue 8. 2010-06-01. PMID:20151363. the nucleus accumbens (nac) plays a central role in motivation and reward. 2010-06-01 2023-08-12 rat
Meg Waraczynski, Jennifer Salemme, Benjamin Farra. Brain stimulation reward is affected by D2 dopamine receptor manipulations in the extended amygdala but not the nucleus accumbens. Behavioural brain research. vol 208. issue 2. 2010-05-25. PMID:20085789. brain stimulation reward is affected by d2 dopamine receptor manipulations in the extended amygdala but not the nucleus accumbens. 2010-05-25 2023-08-12 rat
Kenneth Blum, Thomas J H Chen, Amanda L H Chen, Margaret Madigan, B William Downs, Roger L Waite, Eric R Braverman, Mallory Kerner, Abdalla Bowirrat, John Giordano, Harry Henshaw, Mark S Gol. Do dopaminergic gene polymorphisms affect mesolimbic reward activation of music listening response? Therapeutic impact on Reward Deficiency Syndrome (RDS). Medical hypotheses. vol 74. issue 3. 2010-05-07. PMID:19914781. using fmri, menon and levitin [9] clearly found for the first time that listening to music strongly modulates activity in a network of mesolimbic structures involved in reward processing including the nucleus accumbens (nac) and the ventral tegmental area (vta), as well as the hypothalamus, and insula, which are thought to be involved in regulating autonomic and physiological responses to rewarding and emotional stimuli. 2010-05-07 2023-08-12 human
Francesca M Filbey, Joseph P Schacht, Ursula S Myers, Robert S Chavez, Kent E Hutchiso. Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20010552. the faah group contrasts showed that faah rs324420 c homozygotes also had greater activation in widespread areas within the reward circuit, specifically in the ofc, acg, and nucleus accumbens (nac), as compared with the faah a-allele carriers. 2010-04-28 2023-08-12 human
Joshua W Buckholtz, Michael T Treadway, Ronald L Cowan, Neil D Woodward, Stephen D Benning, Rui Li, M Sib Ansari, Ronald M Baldwin, Ashley N Schwartzman, Evan S Shelby, Clarence E Smith, David Cole, Robert M Kessler, David H Zal. Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits. Nature neuroscience. vol 13. issue 4. 2010-04-22. PMID:20228805. using [(18)f]fallypride positron emission tomography and blood oxygen level-dependent functional magnetic resonance imaging, we found that impulsive-antisocial psychopathic traits selectively predicted nucleus accumbens dopamine release and reward anticipation-related neural activity in response to pharmacological and monetary reinforcers, respectively. 2010-04-22 2023-08-12 Not clear
S N Schiffman. [Changes in neural networks by conditional transgenic approach: a key to our comprehension of neuro-psychiatric disorders in the basal ganglia system]. Bulletin et memoires de l'Academie royale de medecine de Belgique. vol 164. issue 7-9. 2010-04-02. PMID:20218186. the dorsal striatum is central to the motor control and motor learning and the ventral striatum or nucleus accumbens is essential for motivation, the reward system and reinforcement by drugs. 2010-04-02 2023-08-12 Not clear
Helga Höifödt Lidö, Rosita Stomberg, Anne Fagerberg, Mia Ericson, Bo Söderpal. The glycine reuptake inhibitor org 25935 interacts with basal and ethanol-induced dopamine release in rat nucleus accumbens. Alcoholism, clinical and experimental research. vol 33. issue 7. 2010-03-26. PMID:19389199. the mesolimbic dopamine (da) projection from the ventral tegmental area to nucleus accumbens (nac), a central part of the reward system, is activated by ethanol (etoh) and other drugs of abuse. 2010-03-26 2023-08-12 rat
K D Carr, L S Chau, S Cabeza de Vaca, K Gustafson, M Stouffer, D S Tukey, S Restituito, E B Zif. AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19931598. previous findings suggest that neuroadaptations downstream of d-1 dopamine (da) receptor stimulation in nucleus accumbens (nac) are involved in the enhancement of drug reward by chronic food restriction (fr). 2010-03-12 2023-08-12 rat
Claire I Dixon, Hannah V Morris, Gerome Breen, Sylvane Desrivieres, Sarah Jugurnauth, Rebecca C Steiner, Homero Vallada, Camila Guindalini, Ronaldo Laranjeira, Guilherme Messas, Thomas W Rosahl, John R Atack, Dianne R Peden, Delia Belelli, Jeremy J Lambert, Sarah L King, Gunter Schumann, David N Stephen. Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 5. 2010-03-05. PMID:20133874. because gaba(a) receptors containing alpha2 subunits are highly represented in areas of the brain, such as nucleus accumbens (nacc), frontal cortex, and amygdala, regions intimately involved in signaling motivation and reward, we hypothesized that manipulations of this receptor subtype would influence processing of rewards. 2010-03-05 2023-08-12 mouse
Brandon J Aragona, Jeremy J Day, Mitchell F Roitman, Nathan A Cleaveland, R Mark Wightman, Regina M Carell. Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats. The European journal of neuroscience. vol 30. issue 10. 2010-02-26. PMID:19912327. drug seeking is significantly regulated by drug-associated cues and associative learning between environmental cues and cocaine reward is mediated by dopamine transmission within the nucleus accumbens (nac). 2010-02-26 2023-08-12 rat
Reka Daniel, Stefan Pollman. Comparing the neural basis of monetary reward and cognitive feedback during information-integration category learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 1. 2010-02-04. PMID:20053886. our results indicate that, although all other structures implicated in category learning are not significantly affected by altering the type of reward, the nucleus accumbens responds to the positive incentive properties of an expected reward depending on the specific type of the reward. 2010-02-04 2023-08-12 human
Alicia Izquierdo, Elisabeth A Murra. Functional interaction of medial mediodorsal thalamic nucleus but not nucleus accumbens with amygdala and orbital prefrontal cortex is essential for adaptive response selection after reinforcer devaluation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 2. 2010-02-01. PMID:20071531. because both the nucleus accumbens (na) and the mdm are anatomically related to the amygdala and pfo, and because both regions are implicated in reward processing, we tested whether either region necessarily interacts with the amygdala and pfo to mediate reinforcer devaluation effects. 2010-02-01 2023-08-12 monkey
Ian C Webb, Ricardo M Baltazar, Xu Wang, Kyle K Pitchers, Lique M Coolen, Michael N Lehma. Diurnal variations in natural and drug reward, mesolimbic tyrosine hydroxylase, and clock gene expression in the male rat. Journal of biological rhythms. vol 24. issue 6. 2010-01-20. PMID:19926806. to identify potential mechanisms for rhythmicity in reward, levels of tyrosine hydroxylase (th) and core clock proteins (period1 and bmal1) were examined across the day in the ventral tegmental area (vta) and the nucleus accumbens (nacc). 2010-01-20 2023-08-12 rat