| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Wang, Dalong Sun, Bin Pan, Christopher J Roberts, Xinglai Sun, Cecilia J Hillard, Qing-song Li. Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 11. 2011-08-08. PMID:20664582. |
the nucleus accumbens (nac) is a critical component of the reward circuitry, and dysfunction of the nac may account for anhedonia and other symptoms of depression. |
2011-08-08 |
2023-08-12 |
mouse |
| Luke J Chang, Alec Smith, Martin Dufwenberg, Alan G Sanfe. Triangulating the neural, psychological, and economic bases of guilt aversion. Neuron. vol 70. issue 3. 2011-07-11. PMID:21555080. |
we observed increased activation in the insula, supplementary motor area, dorsolateral prefrontal cortex (pfc), and temporal parietal junction when participants were behaving consistent with our model, and found increased activity in the ventromedial pfc, dorsomedial pfc, and nucleus accumbens when they chose to abuse trust and maximize their financial reward. |
2011-07-11 |
2023-08-12 |
human |
| Eliot L Gardne. Addiction and brain reward and antireward pathways. Advances in psychosomatic medicine. vol 30. 2011-07-01. PMID:21508625. |
the core reward circuitry consists of an 'in-series' circuit linking the ventral tegmental area, nucleus accumbens and ventral pallidum via the medial forebrain bundle. |
2011-07-01 |
2023-08-12 |
Not clear |
| Eliot L Gardne. Addiction and brain reward and antireward pathways. Advances in psychosomatic medicine. vol 30. 2011-07-01. PMID:21508625. |
all addictive drugs have in common that they enhance (directly or indirectly or even transsynaptically) dop-aminergic reward synaptic function in the nucleus accumbens. |
2011-07-01 |
2023-08-12 |
Not clear |
| Viviana Trezza, Ruth Damsteegt, E J Marijke Achterberg, Louk J M J Vanderschure. Nucleus accumbens μ-opioid receptors mediate social reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525276. |
nucleus accumbens μ-opioid receptors mediate social reward. |
2011-06-24 |
2023-08-12 |
rat |
| Viviana Trezza, Ruth Damsteegt, E J Marijke Achterberg, Louk J M J Vanderschure. Nucleus accumbens μ-opioid receptors mediate social reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525276. |
here, we studied the neural underpinnings of social reward by investigating the involvement of opioid neurotransmission in the nucleus accumbens (nac) in social play behavior, a highly rewarding social interaction in adolescent rats. |
2011-06-24 |
2023-08-12 |
rat |
| P Zill, V Vielsmeier, A Büttner, W Eisenmenger, F Siedler, B Scheffer, H-J Möller, B Bond. Postmortem proteomic analysis in human amygdala of drug addicts: possible impact of tubulin on drug-abusing behavior. European archives of psychiatry and clinical neuroscience. vol 261. issue 2. 2011-06-21. PMID:20686780. |
besides the ventral tegmental area and the nucleus accumbens as the most investigated brain reward structures, several reports about the relation between volume and activity of the amygdala and drug-seeking behavior have emphasized the central role of the amygdala in the etiology of addiction. |
2011-06-21 |
2023-08-12 |
human |
| Ivan Trujillo-Pisanty, Giovanni Hernandez, Ian Moreau-Debord, Marie-Pierre Cossette, Kent Conover, Joseph F Cheer, Peter Shizga. Cannabinoid receptor blockade reduces the opportunity cost at which rats maintain operant performance for rewarding brain stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 14. 2011-06-09. PMID:21471378. |
by means of microdialysis, we demonstrate that blockade of cb(1) receptors attenuates nucleus accumbens dopamine release in response to rewarding medial forebrain bundle stimulation, and we propose that this action is responsible for the ability of the drug to decrease performance for the electrical reward. |
2011-06-09 |
2023-08-12 |
human |
| Yan-qin Li, Yan-xue Xue, Ying-ying He, Fang-qiong Li, Li-fen Xue, Chun-mei Xu, Todd Charlton Sacktor, Yavin Shaham, Lin L. Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 14. 2011-06-09. PMID:21471379. |
we used conditioned place preference (cpp) and conditioned place aversion (cpa) procedures to study the role of nucleus accumbens pkmζ in the maintenance of drug reward and aversion memories in rats. |
2011-06-09 |
2023-08-12 |
rat |
| D L Robinson, D L Zitzman, K J Smith, L P Spea. Fast dopamine release events in the nucleus accumbens of early adolescent rats. Neuroscience. vol 176. 2011-06-01. PMID:21182904. |
subsecond fluctuations in dopamine (dopamine transients) in the nucleus accumbens are often time-locked to rewards and cues and provide an important learning signal during reward processing. |
2011-06-01 |
2023-08-12 |
rat |
| Jeremy J Day, Joshua L Jones, Regina M Carell. Nucleus accumbens neurons encode predicted and ongoing reward costs in rats. The European journal of neuroscience. vol 33. issue 2. 2011-06-01. PMID:21198983. |
nucleus accumbens neurons encode predicted and ongoing reward costs in rats. |
2011-06-01 |
2023-08-12 |
rat |
| Nancy A Staffend, Caroline M Loftus, Robert L Meise. Estradiol reduces dendritic spine density in the ventral striatum of female Syrian hamsters. Brain structure & function. vol 215. issue 3-4. 2011-05-31. PMID:20953625. |
these results are significant in that they offer a novel mechanism for estradiol actions on a wide variety of nucleus accumbens functions such as motivation or reward as well as their pathological consequences (e.g. |
2011-05-31 |
2023-08-12 |
Not clear |
| R Stark, E Bauer, C J Merz, M Zimmermann, M Reuter, M M Plichta, P Kirsch, K P Lesch, A J Fallgatter, D Vaitl, M J Herrman. ADHD related behaviors are associated with brain activation in the reward system. Neuropsychologia. vol 49. issue 3. 2011-05-27. PMID:21163276. |
neuroimaging studies on attention-deficit/hyperactivity disorder (adhd) suggest dysfunctional reward processing, with hypo-responsiveness during reward anticipation in the reward system including the nucleus accumbens (nacc). |
2011-05-27 |
2023-08-12 |
human |
| Carina Valenzuela, Carolina Aguirre, Valeska Castillo, Ana María Ronco, Miguel Llano. [A role for the endocannabinoid system in obesity]. Revista medica de Chile. vol 138. issue 5. 2011-05-05. PMID:20668819. |
the ecs regulates food ingestion by stimulating a network of orexigenic neurons present in the hypothalamus and reinforcing motivation and reward to food consumption in the nucleus accumbens. |
2011-05-05 |
2023-08-12 |
Not clear |
| Kyohei Mori, Juhyon Kim, Kazuo Sasak. Electrophysiological effects of orexin-B and dopamine on rat nucleus accumbens shell neurons in vitro. Peptides. vol 32. issue 2. 2011-05-05. PMID:21055430. |
the mesolimbic dopamine (da) pathway that projects into the nucleus accumbens (nac) from the ventral tegmental area is deeply involved in the neural mechanisms underlying reward, drug abuse and motivation. |
2011-05-05 |
2023-08-12 |
rat |
| S L Sánchez-Serrano, S L Cruz, M Lama. Repeated toluene exposure modifies the acetylation pattern of histones H3 and H4 in the rat brain. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21146589. |
in order to decipher whether repeated toluene exposure could mediate epigenetic changes in the rat brain, we here analyzed the acetylation pattern of histones h3 and h4 in three brain areas that have been previously associated to substance abuse reward pathways: the nucleus accumbens (nac), the ventral tegmental area (vta) and the central amygdala (cea). |
2011-04-29 |
2023-08-12 |
rat |
| S P Goulding, I Obara, K D Lominac, A T Gould, B W Miller, M Klugmann, K K Szumlinsk. Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? Genes, brain, and behavior. vol 10. issue 1. 2011-04-25. PMID:20807241. |
alcohol-induced increases in nucleus accumbens glutamate actively regulate alcohol consumption, and the alcohol responsiveness of corticoaccumbens glutamate systems relates to genetic variance in alcohol reward. |
2011-04-25 |
2023-08-12 |
mouse |
| E C Muly, M Maddox, Z U Kha. Distribution of D1 and D5 dopamine receptors in the primate nucleus accumbens. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600664. |
the d1 family of dopamine receptors (d1r) play a critical role in modulating reward in the nucleus accumbens (nac). |
2011-04-18 |
2023-08-12 |
Not clear |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
here, we report that cocaine dramatically and dynamically alters heterochromatic histone h3 lysine 9 trimethylation (h3k9me3) in the nucleus accumbens (nac), a key brain reward region. |
2011-04-14 |
2023-08-12 |
Not clear |
| Xiao-Qing Peng, Zheng-Xiong Xi, Xia Li, Krista Spiller, Jie Li, Lauren Chun, Kuo-Ming Wu, Mark Froimowitz, Eliot L Gardne. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 13. 2011-03-03. PMID:20827272. |
systemic administration of 31,345 produced long-lasting enhancement of electrical brain-stimulation reward (bsr) and extracellular nucleus accumbens (nac) dopamine (da). |
2011-03-03 |
2023-08-12 |
Not clear |