| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eva M Marco, Walter Adriani, Lucia A Ruocco, Rossella Canese, Adolfo G Sadile, Giovanni Laviol. Neurobehavioral adaptations to methylphenidate: the issue of early adolescent exposure. Neuroscience and biobehavioral reviews. vol 35. issue 8. 2011-12-01. PMID:21376076. |
moreover, adolescent exposure to mph seems to provoke persistent neurobehavioral consequences: long-term modulation of self-control abilities, decreased sensitivity to natural and drug reward, enhanced stress-induced emotionality, together with an enhanced cortical control over sub-cortical dopamine systems and an enduring up-regulation of htr7 gene expression within the nucleus accumbens (nacc). |
2011-12-01 |
2023-08-12 |
human |
| Helena J V Rutherford, Sarah K Williams, Sheryl Moy, Linda C Mayes, Josephine M John. Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems. Frontiers in psychiatry. vol 2. 2011-11-10. PMID:21779252. |
therefore, addiction reflects the dysregulation between core reward systems, including the prefrontal cortex (pfc), ventral tegmental area (vta), and nucleus accumbens (nac), as well as the hypothalamic-pituitary-adrenal axis and extended amygdala of the stress system. |
2011-11-10 |
2023-08-12 |
human |
| C A Fontes-Ribeiro, E Marques, F C Pereira, A P Silva, T R A Maced. May exercise prevent addiction? Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886560. |
amphetamines exert their persistent addictive effects by activating brain's reward pathways, perhaps through the release of dopamine in the nucleus accumbens (and/or in other places). |
2011-11-10 |
2023-08-12 |
rat |
| John A Clithero, Crystal Reeck, R McKell Carter, David V Smith, Scott A Huette. Nucleus accumbens mediates relative motivation for rewards in the absence of choice. Frontiers in human neuroscience. vol 5. 2011-11-10. PMID:21941472. |
activation in the nucleus accumbens (nacc) and anterior insula (ains) predicted individual variation in relative motivation between our reward modalities. |
2011-11-10 |
2023-08-12 |
human |
| J Alsiö, P K Olszewski, A H Norbäck, Z E A Gunnarsson, A S Levine, C Pickering, H B Schiöt. Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats. Neuroscience. vol 171. issue 3. 2011-10-31. PMID:20875839. |
the nucleus accumbens (nacc) mediates feeding reward; its activity reflects tastants' hedonic value. |
2011-10-31 |
2023-08-12 |
rat |
| Herbert E Covington, Ian Maze, HaoSheng Sun, Howard M Bomze, Kristine D DeMaio, Emma Y Wu, David M Dietz, Mary Kay Lobo, Subroto Ghose, Ezekiel Mouzon, Rachael L Neve, Carol A Tamminga, Eric J Nestle. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. vol 71. issue 4. 2011-10-25. PMID:21867882. |
here, we identify repressive histone methylation in nucleus accumbens (nac), an important brain reward region, as a key mechanism linking cocaine exposure to increased stress vulnerability. |
2011-10-25 |
2023-08-12 |
mouse |
| Candice M Klingerman, Anand Patel, Valerie L Hedges, Robert L Meisel, Jill E Schneide. Food restriction dissociates sexual motivation, sexual performance, and the rewarding consequences of copulation in female Syrian hamsters. Behavioural brain research. vol 223. issue 2. 2011-10-24. PMID:21600244. |
in hamsters, formation of a conditioned place preference (cpp) for copulatory reward is reflected in increased nucleus accumbens (nac) neural activation, measured as immunocytochemical staining for c-fos, the protein product of the immediate-early gene, c-fos. |
2011-10-24 |
2023-08-12 |
Not clear |
| Luis Hernández, Daniel Paredes, Pedro Rad. Feeding behavior as seen through the prism of brain microdialysis. Physiology & behavior. vol 104. issue 1. 2011-10-14. PMID:21549733. |
dopamine (da) in the nucleus accumbens (nac) correlates with food reward, stimulus saliency, and goal directed hyperlocomotion but in the ventromedial hypothalamus da correlates with satiety and hypolocomotion. |
2011-10-14 |
2023-08-12 |
Not clear |
| Jessy John, Rohit Manchand. Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences. vol 36. issue 2. 2011-10-07. PMID:21654085. |
the nucleus accumbens (nac), a critical structure of the brain reward circuit, is implicated in normal goal-directed behaviour and learning as well as pathological conditions like schizophrenia and addiction. |
2011-10-07 |
2023-08-12 |
Not clear |
| Suzanne L Dickson, Emil Egecioglu, Sara Landgren, Karolina P Skibicka, Jörgen A Engel, Elisabet Jerlha. The role of the central ghrelin system in reward from food and chemical drugs. Molecular and cellular endocrinology. vol 340. issue 1. 2011-09-28. PMID:21354264. |
this reward link comprises a dopamine projection from the ventral tegmental area (vta) to the nucleus accumbens together with a cholinergic input, arising primarily from the laterodorsal tegmental area. |
2011-09-28 |
2023-08-12 |
mouse |
| Kathryn E Demos, William M Kelley, Todd F Heatherto. Dietary restraint violations influence reward responses in nucleus accumbens and amygdala. Journal of cognitive neuroscience. vol 23. issue 8. 2011-09-23. PMID:20807052. |
dietary restraint violations influence reward responses in nucleus accumbens and amygdala. |
2011-09-23 |
2023-08-12 |
Not clear |
| Ruth M Krebs, Carsten N Boehler, Tobias Egner, Marty G Woldorf. The neural underpinnings of how reward associations can both guide and misguide attention. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 26. 2011-09-13. PMID:21715640. |
neurally, only relevant reward associations invoked a typical reward-anticipation response in the nucleus accumbens (nacc), which was in turn predictive of behavioral facilitation. |
2011-09-13 |
2023-08-12 |
Not clear |
| Ian C Ballard, Vishnu P Murty, R McKell Carter, Jeffrey J MacInnes, Scott A Huettel, R Alison Adcoc. Dorsolateral prefrontal cortex drives mesolimbic dopaminergic regions to initiate motivated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 28. 2011-09-12. PMID:21753011. |
motivation to obtain reward is thought to depend on the midbrain [particularly the ventral tegmental area (vta)], the nucleus accumbens (nacc), and the dorsolateral prefrontal cortex (dlpfc), but it is not clear how the interactions among these regions relate to reward-motivated behavior. |
2011-09-12 |
2023-08-12 |
human |
| Rahul Pandit, Johannes W de Jong, Louk J M J Vanderschuren, Roger A H Ada. Neurobiology of overeating and obesity: the role of melanocortins and beyond. European journal of pharmacology. vol 660. issue 1. 2011-09-09. PMID:21295024. |
and reward circuitry (the ventral tegmental area and nucleus accumbens) will be evaluated and scrutinized. |
2011-09-09 |
2023-08-12 |
Not clear |
| Kyle S Smith, Kent C Berridge, J Wayne Aldridg. Disentangling pleasure from incentive salience and learning signals in brain reward circuitry. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 27. 2011-09-09. PMID:21670308. |
these results reveal separate neural representations of wanting, liking, and prediction components of the same reward within the nucleus accumbens to ventral pallidum segment of mesocorticolimbic circuitry. |
2011-09-09 |
2023-08-12 |
Not clear |
| Pradeep J Nathan, Edward T Bullmor. From taste hedonics to motivational drive: central μ-opioid receptors and binge-eating behaviour. The international journal of neuropsychopharmacology. vol 12. issue 7. 2011-09-06. PMID:19433009. |
these effects have been linked to direct stimulation of mors and modulation of dopamine release within the reward circuitry including the nucleus accumbens. |
2011-09-06 |
2023-08-12 |
Not clear |
| Matthew B Wilkinson, Caroline Dias, Jane Magida, Michelle Mazei-Robison, MaryKay Lobo, Pamela Kennedy, David Dietz, Herbert Covington, Scott Russo, Rachael Neve, Subroto Ghose, Carol Tamminga, Eric J Nestle. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 25. 2011-09-02. PMID:21697359. |
based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (dvl)-2, as being regulated in the nucleus accumbens (nac), a key brain reward region, in the mouse social defeat model of depression. |
2011-09-02 |
2023-08-12 |
mouse |
| Garret D Stuber, Dennis R Sparta, Alice M Stamatakis, Wieke A van Leeuwen, Juanita E Hardjoprajitno, Saemi Cho, Kay M Tye, Kimberly A Kempadoo, Feng Zhang, Karl Deisseroth, Antonello Bonc. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. vol 475. issue 7356. 2011-08-30. PMID:21716290. |
excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. |
2011-08-30 |
2023-08-12 |
mouse |
| Siri Leknes, Michael Lee, Chantal Berna, Jesper Andersson, Irene Trace. Relief as a reward: hedonic and neural responses to safety from pain. PloS one. vol 6. issue 4. 2011-08-25. PMID:21490964. |
of the brain regions that are involved in mediating pleasure, the nucleus accumbens also signals unexpected reward and positive prediction error. |
2011-08-25 |
2023-08-12 |
human |
| Diane A Lane, June Chan, Carl R Lupica, Virginia M Picke. Cannabinoid-1 receptor gene deletion has a compartment-specific affect on the dendritic and axonal availability of μ-opioid receptors and on dopamine axons in the mouse nucleus accumbens. Synapse (New York, N.Y.). vol 64. issue 12. 2011-08-15. PMID:20939059. |
cannabinoid-type 1 (cb1) receptors are implicated in μ-opioid receptor (μ-or)-dependent reward ascribed partially to mesolimbic dopamine release in the nucleus accumbens (acb) shell. |
2011-08-15 |
2023-08-12 |
mouse |