| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincent N Marty, Igor Spigelma. Long-lasting alterations in membrane properties, k(+) currents, and glutamatergic synaptic currents of nucleus accumbens medium spiny neurons in a rat model of alcohol dependence. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22701402. |
the nucleus accumbens (nacc) is a key structure of the mesolimbic dopaminergic reward system. |
2012-10-02 |
2023-08-12 |
rat |
| Vincent N Marty, Igor Spigelma. Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens. Alcohol (Fayetteville, N.Y.). vol 46. issue 4. 2012-09-25. PMID:22445807. |
the nucleus accumbens (nacc), a central component of the brain reward system, plays a critical role in alcohol-induced neuroadaptive changes underlying alcohol-seeking behaviors. |
2012-09-25 |
2023-08-12 |
Not clear |
| Joshua Kinnison, Srikanth Padmala, Jong-Moon Choi, Luiz Pesso. Network analysis reveals increased integration during emotional and motivational processing. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 24. 2012-09-24. PMID:22699916. |
our findings also revealed several important features of inter-community communication, including notable contributions of the bed nucleus of the stria terminalis, anterior insula, and thalamus during threat and of the caudate and nucleus accumbens during reward. |
2012-09-24 |
2023-08-12 |
human |
| C M Hostetler, K L Bale. DeltaFosB is increased in the nucleus accumbens by amphetamine but not social housing or isolation in the prairie vole. Neuroscience. vol 210. 2012-09-21. PMID:22450232. |
here, we predicted that 10 days of housing with an opposite-sex partner would act as a "social reward," leading to upregulation of Δfosb expression in the nucleus accumbens. |
2012-09-21 |
2023-08-12 |
Not clear |
| Frédéric Huppé-Gourgues, Patricio O'Donnel. D₁-NMDA receptor interactions in the rat nucleus accumbens change during adolescence. Synapse (New York, N.Y.). vol 66. issue 7. 2012-09-17. PMID:22354455. |
these results suggest that d₁-nmda receptor interactions in the nucleus accumbens change during adolescence, a change that may result in different processing of reward functions during this critical developmental stage. |
2012-09-17 |
2023-08-12 |
rat |
| Stephen E Chang, Daniel S Wheeler, Peter C Hollan. Roles of nucleus accumbens and basolateral amygdala in autoshaped lever pressing. Neurobiology of learning and memory. vol 97. issue 4. 2012-09-17. PMID:22469749. |
we suggest that acb is important for initial acquisition of consummatory-like responses that incorporate hedonic aspects of the reward, while bla serves to enhance such incentive salience once it is acquired. |
2012-09-17 |
2023-08-12 |
rat |
| Juan Li, Nuyun Liu, Kangrong Lu, Lei Zhang, Jingjing Gu, Fukun Guo, Shengli An, Lin Zhang, Lu Zhan. Cocaine-induced dendritic remodeling occurs in both D1 and D2 dopamine receptor-expressing neurons in the nucleus accumbens. Neuroscience letters. vol 517. issue 2. 2012-09-14. PMID:22561554. |
repeated exposure to cocaine can induce persistent alterations in the brain's reward system, including increases in the number of dendrites and spine density on medium-sized spiny neurons (msns) in the nucleus accumbens (nac). |
2012-09-14 |
2023-08-12 |
mouse |
| Erik B Oleson, Mark J Ferris, Rodrigo A España, Jill Harp, Sara R Jone. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. European journal of pharmacology. vol 683. issue 1-3. 2012-09-13. PMID:22445882. |
aside from producing the desired histamine reducing effects, many antihistamines can also elicit psychomotor activation and reward, both of which are associated with increased dopamine concentrations in the nucleus accumbens (nac). |
2012-09-13 |
2023-08-12 |
Not clear |
| Jennifer M Mitchell, James P O'Neil, Mustafa Janabi, Shawn M Marks, William J Jagust, Howard L Field. Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbens. Science translational medicine. vol 4. issue 116. 2012-09-06. PMID:22238334. |
drinking alcohol induced opioid release in the nucleus accumbens and orbitofrontal cortex, areas of the brain implicated in reward valuation. |
2012-09-06 |
2023-08-12 |
human |
| Anne Marie Wissman, Renee M May, Catherine S Woolle. Ultrastructural analysis of sex differences in nucleus accumbens synaptic connectivity. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:21987050. |
despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (nac). |
2012-09-04 |
2023-08-12 |
rat |
| Kanji Yoshimoto, Yoshihisa Watanabe, Masaki Tanaka, Minoru Kimur. Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior. The European journal of neuroscience. vol 35. issue 8. 2012-08-27. PMID:22512261. |
dopamine and serotonin (5-ht) in the nucleus accumbens (acc) and ventral tegmental area of the mesoaccumbens reward pathways have been implicated in the mechanisms underlying development of alcohol dependence. |
2012-08-27 |
2023-08-12 |
mouse |
| Geoffrey van der Plasse, Regina Schrama, Sebastiaan P van Seters, Louk J M J Vanderschuren, Herman G M Westenber. Deep brain stimulation reveals a dissociation of consummatory and motivated behaviour in the medial and lateral nucleus accumbens shell of the rat. PloS one. vol 7. issue 3. 2012-08-20. PMID:22428054. |
in view of the possible application of dbs in the treatment of disorders characterized by impaired processing of reward and motivation, like addiction and eating disorders, we examined the effect of dbs of the nucleus accumbens (nacc) on food-directed behavior. |
2012-08-20 |
2023-08-12 |
rat |
| Vincent Vialou, Jian Feng, Alfred J Robison, Stacy M Ku, Deveroux Ferguson, Kimberly N Scobie, Michelle S Mazei-Robison, Ezekiell Mouzon, Eric J Nestle. Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 22. 2012-08-06. PMID:22649236. |
here, we demonstrate a necessary role for two transcription factors, camp response element binding protein (creb) and serum response factor (srf), in mediating this induction within the mouse nucleus accumbens (nac), a key brain reward region. |
2012-08-06 |
2023-08-12 |
mouse |
| Jennifer Francois, Michael W Conway, John P Lowry, Mark D Tricklebank, Gary Gilmou. Changes in reward-related signals in the rat nucleus accumbens measured by in vivo oxygen amperometry are consistent with fMRI BOLD responses in man. NeuroImage. vol 60. issue 4. 2012-08-03. PMID:22361256. |
in the present study, o(2) amperometry was applied to the study of reward processing in the rat nucleus accumbens to validate the technique with a behavioural process known to cause robust signals in human neuroimaging studies. |
2012-08-03 |
2023-08-12 |
human |
| Jennifer Francois, Michael W Conway, John P Lowry, Mark D Tricklebank, Gary Gilmou. Changes in reward-related signals in the rat nucleus accumbens measured by in vivo oxygen amperometry are consistent with fMRI BOLD responses in man. NeuroImage. vol 60. issue 4. 2012-08-03. PMID:22361256. |
this o(2) signal was modulated by cue reversal but not lever reversal, by differences in reward magnitudes and by the motivational state of the animal consistent with previous reports of the role of the nucleus accumbens in both the anticipation and representation of reward value. |
2012-08-03 |
2023-08-12 |
human |
| Manoj A Upadhya, Kartik T Nakhate, Dadasaheb M Kokare, Uday Singh, Praful S Singru, Nishikant K Subheda. CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22186082. |
the opioid-mesolimbic-dopamine circuitry operates between ventral tegmental area (vta) and nucleus accumbens (acb) and serves as a major reward pathway. |
2012-07-27 |
2023-08-12 |
Not clear |
| Tünde Molnár, Arpád Dobolyi, Gabriella Nyitrai, Péter Barabás, László Héja, Zsuzsa Emri, Miklós Palkovits, Julianna Kardo. Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinate. BMC neuroscience. vol 12. 2012-07-26. PMID:21967230. |
the purpose of the present study is to identify the characteristics of atp-evoked glial signalling in the brain reward area, the nucleus accumbens (nac), and thereby to explore the action of citric acid cycle intermediate succinate (suc). |
2012-07-26 |
2023-08-12 |
Not clear |
| Darlene H Brunzell, J Michael McIntos. Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169946. |
before pr, rats received local infusions of 0, 10, or 20 pmol of a selective α7 nachr antagonist, α-conotoxin arib [v11l,v16d] (arib) into the nucleus accumbens (nac) shell or the anterior cingulate cortex, brain areas that contribute to motivation for drug reward. |
2012-07-20 |
2023-08-12 |
rat |
| Erik B Oleson, Michael V Beckert, Joshua T Morra, Carien S Lansink, Roger Cachope, Rehab A Abdullah, Amy L Loriaux, Dustin Schetters, Tommy Pattij, Mitchell F Roitman, Aron H Lichtman, Joseph F Chee. Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. Neuron. vol 73. issue 2. 2012-07-19. PMID:22284189. |
transient increases in nucleus accumbens (nac) dopamine concentration are observed when animals are presented with motivationally salient stimuli and are theorized to energize reward seeking. |
2012-07-19 |
2023-08-12 |
Not clear |
| Amy L Loriaux, Jamie D Roitman, Mitchell F Roitma. Nucleus accumbens shell, but not core, tracks motivational value of salt. Journal of neurophysiology. vol 106. issue 3. 2012-06-26. PMID:21697439. |
the nucleus accumbens (nac) is a critical component of reward circuitry, but recent work suggests that the nac encodes aversion as well as reward. |
2012-06-26 |
2023-08-12 |
rat |