| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rex M Philpot, Lynn Wecker, Cheryl L Kirstei. Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 8. 2010-01-15. PMID:19712739. |
the nucleus accumbens septi undergoes dramatic developmental transitions during the adolescent period, and dopaminergic activity within this region has been identified as a central neurochemical mediator of drug reward, addiction and dependence. |
2010-01-15 |
2023-08-12 |
rat |
| D A Cory-Slechta, M B Virgolini, A Rossi-George, D Weston, M Thiruchelva. Experimental manipulations blunt time-induced changes in brain monoamine levels and completely reverse stress, but not Pb+/-stress-related modifications to these trajectories. Behavioural brain research. vol 205. issue 1. 2010-01-12. PMID:19631235. |
it compared changes in monoamine levels in frontal cortex, nucleus accumbens and striatum of male and female long-evans rat offspring subjected to maternal pb exposure (0, 50 or 150ppm in drinking water from 2 months pre-breeding until pup weaning)+/-prenatal (ps) (restraint on gd16-17) or ps+offspring stress (os; three variable stress challenges to young adults) determined at 2 months of age and at 6 months of age in littermates subsequently exposed either to experimental manipulations (em: daily handling and performance on an operant fixed interval (fi) schedule of food reward), or to no experience (nem; time alone). |
2010-01-12 |
2023-08-12 |
rat |
| Bettina H Bewernick, René Hurlemann, Andreas Matusch, Sarah Kayser, Christiane Grubert, Barbara Hadrysiewicz, Nikolai Axmacher, Matthias Lemke, Deirdre Cooper-Mahkorn, Michael X Cohen, Holger Brockmann, Doris Lenartz, Volker Sturm, Thomas E Schlaepfe. Nucleus accumbens deep brain stimulation decreases ratings of depression and anxiety in treatment-resistant depression. Biological psychiatry. vol 67. issue 2. 2010-01-07. PMID:19914605. |
since anhedonia is a feature of depression and there is evidence of dysfunction of the reward system, dbs to the nucleus accumbens (nacc) might be promising. |
2010-01-07 |
2023-08-12 |
Not clear |
| Allison A Feduccia, Christine L Duvauchell. Auditory stimuli enhance MDMA-conditioned reward and MDMA-induced nucleus accumbens dopamine, serotonin and locomotor responses. Brain research bulletin. vol 77. issue 4. 2010-01-05. PMID:18722516. |
auditory stimuli enhance mdma-conditioned reward and mdma-induced nucleus accumbens dopamine, serotonin and locomotor responses. |
2010-01-05 |
2023-08-12 |
rat |
| Mehmet Sofuoglu, Marc Moone. Cholinergic functioning in stimulant addiction: implications for medications development. CNS drugs. vol 23. issue 11. 2009-12-29. PMID:19845415. |
acetylcholine interacts with the dopaminergic reward system in the ventral tegmental area, nucleus accumbens and prefrontal cortex. |
2009-12-29 |
2023-08-12 |
human |
| Sondra T Bland, Mark R Hutchinson, Steven F Maier, Linda R Watkins, Kirk W Johnso. The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release. Brain, behavior, and immunity. vol 23. issue 4. 2009-12-09. PMID:19486648. |
the present studies extend this line of investigation by exploring whether glial activation may also affect extracellular levels of dopamine (da) in the nucleus accumbens (nac) shell, a neurochemical corollary of morphine-induced drug reward, during a challenge dose of morphine in experiments both with and without precipitated withdrawal. |
2009-12-09 |
2023-08-12 |
rat |
| Yao-Ying Ma, Li Meng, Chang-Yong Guo, Ji-Sheng Han, David Yue-Wei Lee, Cai-Lian Cu. Dose- and time-dependent, context-induced elevation of dopamine and its metabolites in the nucleus accumbens of morphine-induced CPP rats. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19539657. |
the dopamine (da) projections from the ventral tegmental area to the nucleus accumbens (nac) are the key component of the brain reward circuitry. |
2009-12-01 |
2023-08-12 |
rat |
| Yair Bar-Haim, Nathan A Fox, Brenda Benson, Amanda E Guyer, Amber Williams, Eric E Nelson, Koraly Perez-Edgar, Daniel S Pine, Monique Erns. Neural correlates of reward processing in adolescents with a history of inhibited temperament. Psychological science. vol 20. issue 8. 2009-11-30. PMID:19594857. |
adolescents with a history of behavioral inhibition, relative to noninhibited adolescents, showed increased activation in the nucleus accumbens when they believed their selection of an action would affect reward outcome. |
2009-11-30 |
2023-08-12 |
human |
| K M Wassum, S B Ostlund, N T Maidment, B W Ballein. Distinct opioid circuits determine the palatability and the desirability of rewarding events. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 30. 2009-09-28. PMID:19597155. |
whereas opioid circuitry in both the nucleus accumbens and ventral pallidum has been reported to mediate taste-reactivity responses to palatable events, the assignment of reward or inventive value to goal-directed actions has been found to involve the basolateral amygdala. |
2009-09-28 |
2023-08-12 |
rat |
| T Molnár, K Antal, G Nyitrai, Z Emr. gamma-Hydroxybutyrate (GHB) induces GABA(B) receptor independent intracellular Ca2+ transients in astrocytes, but has no effect on GHB or GABA(B) receptors of medium spiny neurons in the nucleus accumbens. Neuroscience. vol 162. issue 2. 2009-09-16. PMID:19446011. |
we report on cellular actions of the illicit recreational drug gamma-hydroxybutyrate (ghb) in the brain reward area nucleus accumbens. |
2009-09-16 |
2023-08-12 |
mouse |
| V L Hedges, S Chakravarty, E J Nestler, R L Meise. Delta FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters. Genes, brain, and behavior. vol 8. issue 4. 2009-09-11. PMID:19566711. |
delta fosb overexpression in the nucleus accumbens enhances sexual reward in female syrian hamsters. |
2009-09-11 |
2023-08-12 |
Not clear |
| Darlene H Brunzell, Yann S Mineur, Rachael L Neve, Marina R Picciott. Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19212318. |
previous studies have implicated nucleus accumbens (nac) creb activity in the modulation of cocaine and morphine reward, and have shown that nicotine conditioned place preference (cpp) is associated with nac creb activation. |
2009-09-02 |
2023-08-12 |
mouse |
| Luke E Stoeckel, Jieun Kim, Rosalyn E Weller, James E Cox, Edwin W Cook, Barry Horwit. Effective connectivity of a reward network in obese women. Brain research bulletin. vol 79. issue 6. 2009-09-02. PMID:19467298. |
the deficient projections from the amygdala might relate to suboptimal modulation of the affective/emotional aspects of a food's reward value or an associated cue's motivational salience, whereas increased orbitofrontal cortex to nucleus accumbens connectivity might contribute to a heightened drive to eat in response to a food cue. |
2009-09-02 |
2023-08-12 |
Not clear |
| D A Simmons, D B Neil. Functional interaction between the basolateral amygdala and the nucleus accumbens underlies incentive motivation for food reward on a fixed ratio schedule. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19344638. |
functional interaction between the basolateral amygdala and the nucleus accumbens underlies incentive motivation for food reward on a fixed ratio schedule. |
2009-08-20 |
2023-08-12 |
rat |
| D A Simmons, D B Neil. Functional interaction between the basolateral amygdala and the nucleus accumbens underlies incentive motivation for food reward on a fixed ratio schedule. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19344638. |
the ability for incentive properties of reward stimuli to maintain motivated behavior in the absence of the rewards themselves may be reliant in part on a glutamatergic projection from the basolateral (bla) amygdala to the nucleus accumbens septi (nas). |
2009-08-20 |
2023-08-12 |
rat |
| B M Geiger, M Haburcak, N M Avena, M C Moyer, B G Hoebel, E N Potho. Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409204. |
the mesolimbic dopamine system, and the nucleus accumbens in particular, underlies both food and drug reward. |
2009-08-20 |
2023-08-12 |
rat |
| L Kokarovtseva, T Jaciw-Zurakiwsky, R Mendizabal Arbocco, M V Frantseva, J L Perez Velazque. Excitability and gap junction-mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409225. |
excitability and gap junction-mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats. |
2009-08-20 |
2023-08-12 |
rat |
| L Kokarovtseva, T Jaciw-Zurakiwsky, R Mendizabal Arbocco, M V Frantseva, J L Perez Velazque. Excitability and gap junction-mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409225. |
the nucleus accumbens (acb) is a part of the striatum which integrates information from cortical and limbic brain structures, and mediates behaviors which reinforce reward. |
2009-08-20 |
2023-08-12 |
rat |
| L Kokarovtseva, T Jaciw-Zurakiwsky, R Mendizabal Arbocco, M V Frantseva, J L Perez Velazque. Excitability and gap junction-mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409225. |
in order to gain insight into functional aspects of the neural information processing at the level of the striatum, we explored the possible role of acb gap junctional communication and chemical synapses on reward self-stimulation in rats using positive reinforcement. |
2009-08-20 |
2023-08-12 |
rat |
| L Kokarovtseva, T Jaciw-Zurakiwsky, R Mendizabal Arbocco, M V Frantseva, J L Perez Velazque. Excitability and gap junction-mediated mechanisms in nucleus accumbens regulate self-stimulation reward in rats. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409225. |
we conclude that reward behaviors depend to a great extent on both excitability and gap junction-mediated mechanisms in acb neuronal networks. |
2009-08-20 |
2023-08-12 |
rat |