| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ranjithkumar Chellian, Isaac Wilks, Brandon Levin, Song Xue, Azin Behnood-Rod, Ryann Wilson, Megan McCarthy, Abhigyan Ravula, Hardik Chandasana, Hartmut Derendorf, Adriaan W Bruijnzee. Tobacco smoke exposure enhances reward sensitivity in male and female rats. Psychopharmacology. vol 238. issue 3. 2021-03-15. PMID:33410984. |
systemic administration of the tobacco smoke constituent nicotine stimulates brain reward function in rats. |
2021-03-15 |
2023-08-13 |
rat |
| Skylar Y Cooper, Brandon J Henderso. The Impact of Electronic Nicotine Delivery System (ENDS) Flavors on Nicotinic Acetylcholine Receptors and Nicotine Addiction-Related Behaviors. Molecules (Basel, Switzerland). vol 25. issue 18. 2021-03-11. PMID:32942576. |
thus, there is a broad understanding of the neurobiological effects that menthol plus nicotine has on the brain including enhancing nicotine reward, altering nicotinic acetylcholine receptor number and function, and altering midbrain neuron excitability. |
2021-03-11 |
2023-08-13 |
Not clear |
| Emmi M Tiili, Natalia V Mitiushkina, Olga A Sukhovskaya, Evgeny N Imyanitov, Ari P Hirvone. The effect of SLC6A3 variable number of tandem repeats and methylation levels on individual susceptibility to start tobacco smoking and on the ability of smokers to quit smoking. Pharmacogenetics and genomics. vol 30. issue 6. 2021-03-08. PMID:32371614. |
nicotine acts through the dopamine pathway in the brain affecting reward processing through cigarette consumption. |
2021-03-08 |
2023-08-13 |
Not clear |
| A L Wong, S M McElroy, J M Robinson, S M Mulloy, F K El Banna, A C Harris, M G LeSage, A M Le. Flavor-specific enhancement of electronic cigarette liquid consumption and preference in mice. Drug and alcohol dependence. vol 211. 2021-03-02. PMID:32354580. |
to determine how the abuse liability of electronic cigarette liquids (e-liquids) differs from nicotine alone, and to determine the impact of flavor, we compared nicotine-containing fruit- and tobacco-flavored e-liquids, and their nicotine-free versions, to nicotine alone in mouse models of oral consumption, reward and aversion. |
2021-03-02 |
2023-08-13 |
mouse |
| Melissa Herman, Robert Tarra. E-cigarettes, nicotine, the lung and the brain: multi-level cascading pathophysiology. The Journal of physiology. vol 598. issue 22. 2021-03-01. PMID:32515030. |
nicotine's reinforcing properties are primarily mediated by activation of the brain's mesolimbic reward circuitry and release of the neurotransmitter dopamine that contribute to the development of addiction. |
2021-03-01 |
2023-08-13 |
human |
| Alice V Ely, Kanchana Jagannathan, Nathan Hager, Ariel Ketcherside, Teresa R Franklin, Reagan R Wetheril. Double jeopardy: Comorbid obesity and cigarette smoking are linked to neurobiological alterations in inhibitory control during smoking cue exposure. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:31069895. |
research suggests that overlapping pathophysiology may contribute to obesity and nicotine use disorder (nud), yet no studies have investigated the effect of obesity on neural response to reward stimuli in nud. |
2021-02-16 |
2023-08-13 |
human |
| Wan-Sen Yan, Ruo-Ting Chen, Meng-Meng Liu, Dan-Hui Zhen. Monetary Reward Discounting, Inhibitory Control, and Trait Impulsivity in Young Adults With Internet Gaming Disorder and Nicotine Dependence. Frontiers in psychiatry. vol 12. 2021-02-16. PMID:33584390. |
monetary reward discounting, inhibitory control, and trait impulsivity in young adults with internet gaming disorder and nicotine dependence. |
2021-02-16 |
2023-08-13 |
Not clear |
| Wan-Sen Yan, Ruo-Ting Chen, Meng-Meng Liu, Dan-Hui Zhen. Monetary Reward Discounting, Inhibitory Control, and Trait Impulsivity in Young Adults With Internet Gaming Disorder and Nicotine Dependence. Frontiers in psychiatry. vol 12. 2021-02-16. PMID:33584390. |
the present study thus aimed to explore the associations of reward processing and inhibitory control with igd and nicotine dependence (nd) in young adults. |
2021-02-16 |
2023-08-13 |
Not clear |
| Briana J Hempel, Mariam Melkumyan, Madeline E Crissman, Chloe A Winston, Jacob Madar, Anthony L Rile. Pre-conception exposure to THC fails to impact nicotine reward in adult offspring. Pharmacology, biochemistry, and behavior. vol 197. 2021-02-08. PMID:32710886. |
pre-conception exposure to thc fails to impact nicotine reward in adult offspring. |
2021-02-08 |
2023-08-13 |
Not clear |
| Frances M Lesli. Unique, long-term effects of nicotine on adolescent brain. Pharmacology, biochemistry, and behavior. vol 197. 2021-02-08. PMID:32738256. |
both acute and chronic effects of nicotine on brain biochemistry and behavior, particularly drug reward, aversion, cognition and emotion, are evaluated. |
2021-02-08 |
2023-08-13 |
human |
| Xiaodan Li, Shen You, Jian Xiong, Yamin Qiao, Jinpeng Yu, Dongting Zhangsun, Sulan Lu. α-Conotoxin TxID and [S9K]TxID, α3β4 nAChR Antagonists, Attenuate Expression and Reinstatement of Nicotine-Induced Conditioned Place Preference in Mice. Marine drugs. vol 18. issue 12. 2021-01-13. PMID:33339145. |
the α3β4 nicotinic acetylcholine receptor (nachr) is strongly associated with nicotine reward and withdrawal symptom. |
2021-01-13 |
2023-08-13 |
mouse |
| Angela M Lee, Cali A Calarco, Sherry A McKee, Yann S Mineur, Marina R Picciott. Variability in nicotine conditioned place preference and stress-induced reinstatement in mice: Effects of sex, initial chamber preference, and guanfacine. Genes, brain, and behavior. vol 19. issue 3. 2021-01-04. PMID:31364813. |
studies suggest that sex-specific interactions between nicotine reward and stress contribute to these sex differences. |
2021-01-04 |
2023-08-13 |
mouse |
| Hasan Alhaddad, Woonyen Wong, Adam T Sari, Laura E Crotty Alexander, Youssef Sar. Effects of 3-Month Exposure to E-Cigarette Aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice. Toxics. vol 8. issue 4. 2020-12-26. PMID:33137879. |
in this study, we evaluated the effect of three months' continuous exposure to e-cig vapor (juul pods), containing a high nicotine concentration, on the expression of glutamate receptors and transporters in drug reward brain regions such as the nucleus accumbens (nac) core (nac-core), nac shell (nac-shell) and hippocampus (hip) in female c57bl/6 mice. |
2020-12-26 |
2023-08-13 |
mouse |
| Kenneth Blum, Peter K Thanos, Marlene Oscar-Berman, Marcelo Febo, David Baron, Rajendra D Badgaiyan, Eliot Gardner, Zsolt Demetrovics, Claudia Fahlke, Brett C Haberstick, Kristina Dushaj, Mark S Gol. Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction. Journal of reward deficiency syndrome. vol 1. issue 3. 2020-10-01. PMID:27398406. |
in terms of chronic addictions, others have shown a blunted responsivity at brain reward sites with food, nicotine, and even gambling behavior. |
2020-10-01 |
2023-08-13 |
Not clear |
| Hyunchan Lee, Sooyeon Chung, Jihyun No. Maternal Nicotine Exposure During Late Gestation and Lactation Increases Anxiety-Like and Impulsive Decision-Making Behavior in Adolescent Offspring of Rat. Toxicological research. vol 32. issue 4. 2020-10-01. PMID:27818729. |
moreover, such nicotine exposed adolescent offspring rats showed impulsive decision making which chose the instant reward in a decision-making situation. |
2020-10-01 |
2023-08-13 |
human |
| Robert S Schick, Thomas W Kelsey, John Marston, Kay Samson, Gerald W Humphri. MapMySmoke: feasibility of a new quit cigarette smoking mobile phone application using integrated geo-positioning technology, and motivational messaging within a primary care setting. Pilot and feasibility studies. vol 4. 2020-10-01. PMID:28725452. |
pharmaceutical treatment can improve these rates by lowering the overall reward factor of nicotine. |
2020-10-01 |
2023-08-13 |
Not clear |
| Cheng Xiao, Chun-Yi Zhou, Jin-Hong Jiang, Cui Yi. Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence. Acta pharmacologica Sinica. vol 41. issue 1. 2020-10-01. PMID:31554960. |
in this review, we describe the anatomical organization of the cholinergic system and the key nachr subtypes mediating cholinergic regulation of da transmission and nicotine reward and dependence, in an effort to identify potential targets for smoking intervention. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mehmet Atilla Uysal, Ülgen Sever, Ayşe Feyda Nursal, Sacide Pehlİva. Dopamine D4 Receptor Gene Exon III VNTR Variant Influences Smoking Status in Turkish Population. Noro psikiyatri arsivi. vol 56. issue 4. 2020-10-01. PMID:31903031. |
dopaminergic gene variants may affect nicotine dependence through their possible impact on the dopamine reward pathway. |
2020-10-01 |
2023-08-13 |
Not clear |
| B Froeliger, A R Mathew, P A McConnell, C Eichberg, M E Saladin, M J Carpenter, E L Garlan. Restructuring Reward Mechanisms in Nicotine Addiction: A Pilot fMRI Study of Mindfulness-Oriented Recovery Enhancement for Cigarette Smokers. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28373890. |
restructuring reward mechanisms in nicotine addiction: a pilot fmri study of mindfulness-oriented recovery enhancement for cigarette smokers. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena Mariyath P M, Nabeela Khanam, M Mobarak Hossai. Exploring the potential role of sonic hedgehog cell signalling pathway in antidepressant effects of nicotine in chronic unpredictable mild stress rat model. Heliyon. vol 5. issue 5. 2020-09-30. PMID:31193084. |
nicotine abuse is the concerted effort to feel reward and fight depression in depressed individuals. |
2020-09-30 |
2023-08-13 |
rat |