| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena Mariyath P M, Nabeela Khanam, M Mobarak Hossai. Exploring the potential role of sonic hedgehog cell signalling pathway in antidepressant effects of nicotine in chronic unpredictable mild stress rat model. Heliyon. vol 5. issue 5. 2020-09-30. PMID:31193084. |
the underlying mechanism of nicotine is to activate the brain reward system in the central nervous system and provide an antidepressant effect. |
2020-09-30 |
2023-08-13 |
rat |
| Alexis E Whitton, Alan I Green, Diego A Pizzagalli, Robert M Roth, Jill M Williams, Mary F Brunett. Potent Dopamine D2 Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia. Schizophrenia bulletin. vol 45. issue 6. 2020-09-16. PMID:30690638. |
because activation of d2 receptors mediates motivation for nicotine, we examined whether potent d2 antagonists would diminish nicotine's ability to stimulate reward processing-a mechanism that may drive compensatory increases in smoking. |
2020-09-16 |
2023-08-13 |
human |
| Raghunath Singh, Yashika Bansal, Ishwar Parhar, Anurag Kuhad, Tomoko Sog. Neuropsychiatric implications of transient receptor potential vanilloid (TRPV) channels in the reward system. Neurochemistry international. vol 131. 2020-09-03. PMID:31494132. |
recent evidence has highlighted trpv channels as potential targets for understanding modulation of the reward system and various forms of addiction (opioids, cocaine, amphetamines, alcohol, nicotine, cannabis). |
2020-09-03 |
2023-08-13 |
Not clear |
| Jean R Geste, Brandon Levin, Isaac Wilks, Marjory Pompilus, Xiping Zhang, Karyn A Esser, Marcelo Febo, Laura O'Dell, Adriaan W Bruijnzee. Relationship Between Nicotine Intake and Reward Function in Rats With Intermittent Short Versus Long Access to Nicotine. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 22. issue 2. 2020-08-25. PMID:30958557. |
relationship between nicotine intake and reward function in rats with intermittent short versus long access to nicotine. |
2020-08-25 |
2023-08-13 |
rat |
| Jean R Geste, Brandon Levin, Isaac Wilks, Marjory Pompilus, Xiping Zhang, Karyn A Esser, Marcelo Febo, Laura O'Dell, Adriaan W Bruijnzee. Relationship Between Nicotine Intake and Reward Function in Rats With Intermittent Short Versus Long Access to Nicotine. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 22. issue 2. 2020-08-25. PMID:30958557. |
animal studies have shown that noncontingent nicotine administration enhances brain reward function and leads to dependence. |
2020-08-25 |
2023-08-13 |
rat |
| Jean R Geste, Brandon Levin, Isaac Wilks, Marjory Pompilus, Xiping Zhang, Karyn A Esser, Marcelo Febo, Laura O'Dell, Adriaan W Bruijnzee. Relationship Between Nicotine Intake and Reward Function in Rats With Intermittent Short Versus Long Access to Nicotine. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 22. issue 2. 2020-08-25. PMID:30958557. |
however, little is known about the effects of nicotine self-administration on the state of the reward system. |
2020-08-25 |
2023-08-13 |
rat |
| Benedetto Romoli, Adrian F Lozada, Ivette M Sandoval, Fredric P Manfredsson, Thomas S Hnasko, Darwin K Berg, Davide Dulci. Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31202491. |
nicotine intake induces addiction through neuroplasticity of the reward circuitry, altering the activity of dopaminergic neurons of the ventral tegmental area. |
2020-08-13 |
2023-08-13 |
Not clear |
| Burt M Shar. Basolateral amygdala, nicotinic cholinergic receptors, and nicotine: Pharmacological effects and addiction in animal models and humans. The European journal of neuroscience. vol 50. issue 3. 2020-08-07. PMID:29802666. |
in essence, bla is necessary for behavioral responses to stimuli that evoke anxiety and fear; reinstatement of cue-induced drug seeking; responding to second-order cues conditioned to abused drugs; reacquisition of amplified nicotine self-administration due to chronic stress during abstinence; and to promote responding for natural reward. |
2020-08-07 |
2023-08-13 |
human |
| Zhujing Shen, Peiyu Huang, Chao Wang, Wei Qian, Xiao Luo, Quanquan Gu, Huan Chen, Hongjuan Wang, Yihong Yang, Minming Zhan. Interactions between monoamine oxidase A rs1137070 and smoking on brain structure and function in male smokers. The European journal of neuroscience. vol 50. issue 3. 2020-08-07. PMID:30456877. |
these findings suggest that maoa rs1137070 contributes to the susceptibility to nicotine dependence through its influence on brain circuits involved in reward and attention, and interacts with smoking in the progression. |
2020-08-07 |
2023-08-13 |
Not clear |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
several studies have shown that nicotine produces long-lasting effects on gene expression within many brain regions, including the ventral tegmental area (vta), which is the origin of dopaminergic neurons and the dopamine reward pathway. |
2020-07-27 |
2023-08-13 |
rat |
| Samantha N Hellberg, Trinity I Russell, Mike J F Robinso. Cued for risk: Evidence for an incentive sensitization framework to explain the interplay between stress and anxiety, substance abuse, and reward uncertainty in disordered gambling behavior. Cognitive, affective & behavioral neuroscience. vol 19. issue 3. 2020-07-17. PMID:30357661. |
here, we review the literature on how cue attraction and reward uncertainty may underlie gambling pathology, and examine how this framework may advance our understanding of co-mordidity with substance-use disorders (e.g., alcohol, nicotine) and anxiety disorders. |
2020-07-17 |
2023-08-13 |
Not clear |
| Andrew R Abela, Zhaoxia Li, Anh D Lê, Paul J Fletche. Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food. Addiction biology. vol 24. issue 4. 2020-07-14. PMID:29575323. |
to determine the specificity of its effect on nicotine reward, we also tested the effect of clozapine on responding for food reinforcement under fixed ratio and progressive ratio schedules. |
2020-07-14 |
2023-08-13 |
rat |
| Andrew R Abela, Zhaoxia Li, Anh D Lê, Paul J Fletche. Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food. Addiction biology. vol 24. issue 4. 2020-07-14. PMID:29575323. |
we show that clozapine inhibits nicotine self-administration and reinstatement of nicotine-seeking but also increases the amount of effort that rats will exert for food reward. |
2020-07-14 |
2023-08-13 |
rat |
| Andrew R Abela, Zhaoxia Li, Anh D Lê, Paul J Fletche. Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food. Addiction biology. vol 24. issue 4. 2020-07-14. PMID:29575323. |
in contrast, haloperidol at a wide range of doses attenuated responding for nicotine and food reward, suggestive of a non-specific reduction in reinforcer efficacy. |
2020-07-14 |
2023-08-13 |
rat |
| Sijie Tan, Song Xue, Azin Behnood-Rod, Ranjithkumar Chellian, Ryann Wilson, Parker Knight, Stefany Panunzio, Hannah Lyons, Marcelo Febo, Adriaan W Bruijnzee. Sex differences in the reward deficit and somatic signs associated with precipitated nicotine withdrawal in rats. Neuropharmacology. vol 160. 2020-07-08. PMID:31487496. |
sex differences in the reward deficit and somatic signs associated with precipitated nicotine withdrawal in rats. |
2020-07-08 |
2023-08-13 |
rat |
| Sijie Tan, Song Xue, Azin Behnood-Rod, Ranjithkumar Chellian, Ryann Wilson, Parker Knight, Stefany Panunzio, Hannah Lyons, Marcelo Febo, Adriaan W Bruijnzee. Sex differences in the reward deficit and somatic signs associated with precipitated nicotine withdrawal in rats. Neuropharmacology. vol 160. 2020-07-08. PMID:31487496. |
there was no sex difference in the reward deficit during spontaneous nicotine withdrawal. |
2020-07-08 |
2023-08-13 |
rat |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (nac) shell and increasing nac shell bdnf is sufficient to enhance ethanol reward in naïve wistar rats. |
2020-06-30 |
2023-08-13 |
rat |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. The modulatory role of nicotine on cognitive and non-cognitive functions. Brain research. vol 1710. 2020-06-25. PMID:30529105. |
nicotine, as the main component of tobacco, plays a key role in various behaviors of both humans and animals including reward, addiction, learning and memory, anxiety, pain as well as body weight and temperature. |
2020-06-25 |
2023-08-13 |
Not clear |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. The modulatory role of nicotine on cognitive and non-cognitive functions. Brain research. vol 1710. 2020-06-25. PMID:30529105. |
the mesocorticolimbic dopamine system mediates the processing of reward, learning and memory behaviors produced by nicotine. |
2020-06-25 |
2023-08-13 |
Not clear |
| Jessica S Flannery, Michael C Riedel, Ranjita Poudel, Angela R Laird, Thomas J Ross, Betty Jo Salmeron, Elliot A Stein, Matthew T Sutherlan. Habenular and striatal activity during performance feedback are differentially linked with state-like and trait-like aspects of tobacco use disorder. Science advances. vol 5. issue 10. 2020-05-19. PMID:31633021. |
the habenula, an epithalamic nucleus involved in reward and aversive processing, may contribute to negative reinforcement mechanisms maintaining nicotine use. |
2020-05-19 |
2023-08-13 |
Not clear |