| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra N Palmisano, Robert S Astu. Nicotine Facilitation of Conditioned Place Preference to Food Reward in Humans. Substance use & misuse. vol 55. issue 13. 2021-06-24. PMID:32720546. |
to investigate whether nicotine also enhances reward in humans, we used a virtual translation of the conditioned place preference (cpp) paradigm to examine nicotine's reward-enhancing effects using a low-dose 2 mg nicotine lozenge targeted to a mild use population. |
2021-06-24 |
2023-08-13 |
Not clear |
| T C Peixoto, E G Moura, P N Soares, V S T Rodrigues, S Claudio-Neto, E Oliveira, A C Manhães, P C Lisbo. Nicotine exposure during lactation causes disruption of hedonic eating behavior and alters dopaminergic system in adult female rats. Appetite. vol 160. 2021-06-24. PMID:33453337. |
nicotine is transferred through milk and alters the dopaminergic reward system of adult male rats, reducing dopamine action in the nucleus accumbens (nac) and hypothalamic arcuate nucleus. |
2021-06-24 |
2023-08-13 |
rat |
| Anjelica Cardenas, Maricela Martinez, Alejandra Saenz Mejia, Shahrdad Lotfipou. Early adolescent subchronic low-dose nicotine exposure increases subsequent cocaine and fentanyl self-administration in Sprague-Dawley rats. Behavioural pharmacology. vol 32. issue 1. 2021-06-21. PMID:32960853. |
preclinical studies have shown that nicotine exposure during early adolescence, but not adulthood, increases subsequent drug intake and reward. |
2021-06-21 |
2023-08-13 |
rat |
| Xiao Lin, Jiahui Deng, Le Shi, Qiandong Wang, Peng Li, Hui Li, Jiajia Liu, Jianyu Que, Suhua Chang, Yanping Bao, Jie Shi, Daniel R Weinberger, Ping Wu, Lin L. Neural substrates of smoking and reward cue reactivity in smokers: a meta-analysis of fMRI studies. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32184386. |
with the escalation of nicotine dependence, nicotine appears to exert dynamic effects on reward processing, based on incentive sensitization theory and reward deficiency syndrome theory. |
2021-06-18 |
2023-08-13 |
Not clear |
| Skylar Y Cooper, Austin T Akers, Brandon J Henderso. Green Apple e-Cigarette Flavorant Farnesene Triggers Reward-Related Behavior by Promoting High-Sensitivity nAChRs in the Ventral Tegmental Area. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32747456. |
following previous studies demonstrating the green apple flavorant, farnesol, enhances nicotine reward and exhibits rewarding properties without nicotine, this work focuses on the green apple flavorant, farnesene, for its impact on vaping-related behaviors. |
2021-06-18 |
2023-08-13 |
mouse |
| Austin T Akers, Skylar Y Cooper, Zachary J Baumgard, Gabriella P Casinelli, Alicia J Avelar, Brandon J Henderso. Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32988984. |
previous reports indicate that nicotine reward is mediated through α4β2*, α6β2*, and α4α6β2* nicotinic acetylcholine receptors (nachrs; * indicates that additional nachr subunits may be present). |
2021-06-18 |
2023-08-13 |
mouse |
| Kainan S Wang, Maya Zegel, Elena Molokotos, Lauren V Moran, David P Olson, Diego A Pizzagalli, Amy C Jane. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31931509. |
the acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. |
2021-05-27 |
2023-08-13 |
Not clear |
| Kainan S Wang, Maya Zegel, Elena Molokotos, Lauren V Moran, David P Olson, Diego A Pizzagalli, Amy C Jane. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31931509. |
this anticipatory effect is selective as no clear evidence has emerged showing that nicotine acutely changes reward receipt reactivity. |
2021-05-27 |
2023-08-13 |
Not clear |
| Kainan S Wang, Maya Zegel, Elena Molokotos, Lauren V Moran, David P Olson, Diego A Pizzagalli, Amy C Jane. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31931509. |
given nicotine's influence on nacc reactivity and connectivity, it is plausible that nicotine acutely induces this shift and alters nacc functional connectivity during reward processing. |
2021-05-27 |
2023-08-13 |
Not clear |
| Kainan S Wang, Maya Zegel, Elena Molokotos, Lauren V Moran, David P Olson, Diego A Pizzagalli, Amy C Jane. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31931509. |
the current findings significantly improve our understanding of how nicotine changes corticostriatal circuit function and communication during distinct phases of reward processing and critically show that these alterations happen acutely following a single dose. |
2021-05-27 |
2023-08-13 |
Not clear |
| Manoj A Upadhya, Harshita M Upadhya, Chandrashekhar D Borkar, Amit G Choudhary, Uday Singh, Priyanka Chavan, Amul Sakharkar, Praful Singru, Nishikant K Subhedar, Dadasaheb M Kokar. Nicotine-induced Brain Stimulation Reward is Modulated by Melanocortin-4 Receptors in Ovariectomized Rats. Neuroscience. vol 431. 2021-05-14. PMID:32035118. |
prior treatment with sub-effective doses of α-msh or ndp-msh potentiated the reward effect of nicotine, but was attenuated by hs014. |
2021-05-14 |
2023-08-13 |
rat |
| Andrea Stojakovic, Syed Muzzammil Ahmad, Kabirullah Lutf. Alterations of Amphetamine Reward by Prior Nicotine and Alcohol Treatment: The Role of Age and Dopamine. Brain sciences. vol 11. issue 4. 2021-04-28. PMID:33810331. |
alterations of amphetamine reward by prior nicotine and alcohol treatment: the role of age and dopamine. |
2021-04-28 |
2023-08-13 |
mouse |
| Andrea Stojakovic, Syed Muzzammil Ahmad, Kabirullah Lutf. Alterations of Amphetamine Reward by Prior Nicotine and Alcohol Treatment: The Role of Age and Dopamine. Brain sciences. vol 11. issue 4. 2021-04-28. PMID:33810331. |
we determined whether prior nicotine and alcohol treatment would alter amphetamine reward. |
2021-04-28 |
2023-08-13 |
mouse |
| Dirk Alexander Wittekind, Jürgen Kratzsch, Roland Mergl, Cornelia Enzenbach, Veronika Witte, Arno Villringer, Michael Klug. Higher fasting ghrelin serum levels in active smokers than in former and never-smokers. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 21. issue 10. 2021-04-27. PMID:31552785. |
ghrelin, an orexigenic peptide hormone, promotes drug reward and is suspected to play a role in nicotine dependence. |
2021-04-27 |
2023-08-13 |
Not clear |
| Lin Chen, Qin Ru, Mei Zhou, Yu Xiang W. [Advances in Immunotherapy for Drug Addiction]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 43. issue 1. 2021-04-27. PMID:33663672. |
drug addiction is a major worldwide medical and social problem.cocaine,nicotine,methamphetamine,heroin and other psychoactive substances,with small molecular weight,can easily cross the blood-brain barrier and eventually lead to addiction and other serious neuropsychological damage.there is no effective cure for addiction currently.the drug-antibody complex formed on the basis of active or passive immunotherapy could not cross the blood-brain barrier,which reduces the concentration of the free active drug and prevents its distribution in the brain,thereby weakening the drug addiction-related reward effects.it provides a promising way for the treatment of drug addiction.this article reviews the progress of immunotherapy against psychoactive substances such as cocaine,nicotine,methamphetamine and heroin in the past 50 years from the aspects of active immunity,passive immunity,drug metabolism-related enzymes,adjuvants and so on.the goal is to provide some ideas for the development of agents for the treatment of psychoactive substance addiction. |
2021-04-27 |
2023-08-13 |
Not clear |
| Janell R Richardson, Laura E O'Dell, Arbi Nazaria. Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model. Neuroscience letters. vol 721. 2021-04-19. PMID:32036029. |
examination of nicotine and saccharin reward in the goto-kakizaki diabetic rat model. |
2021-04-19 |
2023-08-13 |
rat |
| Janell R Richardson, Laura E O'Dell, Arbi Nazaria. Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model. Neuroscience letters. vol 721. 2021-04-19. PMID:32036029. |
it is presently unclear whether this enhancement of nicotine reward can be demonstrated in other insulin resistant rat models. |
2021-04-19 |
2023-08-13 |
rat |
| Janell R Richardson, Laura E O'Dell, Arbi Nazaria. Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model. Neuroscience letters. vol 721. 2021-04-19. PMID:32036029. |
this study aimed to determine if a similar increase in nicotine reward is found in goto-kakizaki (gk) rats, a model of the spontaneous formation of insulin resistance in an inbred sub-strain of wistar rat. |
2021-04-19 |
2023-08-13 |
rat |
| Franco Viscarra, Juan González-Gutierrez, Erica Esparza, Carla Figueroa, Pablo Paillali, Martin Hödar-Salazar, Camilo Cespedes, Gabriel Quiroz, Ramón Sotomayor-Zárate, Miguel Reyes-Parada, Isabel Bermúdez, Patricio Iturriaga-Vásque. Nicotinic Antagonist UFR2709 Inhibits Nicotine Reward and Decreases Anxiety in Zebrafish. Molecules (Basel, Switzerland). vol 25. issue 13. 2021-03-26. PMID:32630020. |
nicotinic antagonist ufr2709 inhibits nicotine reward and decreases anxiety in zebrafish. |
2021-03-26 |
2023-08-13 |
zebrafish |
| Chao Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Shuyue Wang, Yeerfan Jiaerken, Xiao Luo, Kaicheng Li, Qingze Zeng, Cheng Zhou, Yihong Yang, Minming Zhan. Increased striatal functional connectivity is associated with improved smoking cessation outcomes: A preliminary study. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32436626. |
the striatum is the critical area of reward processing and has been repeatedly linked to nicotine addiction. |
2021-03-25 |
2023-08-13 |
human |