| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sergios Charntikov, Steven T Pittenger, Natashia Swalve, Scott T Barrett, Rick A Bevin. Conditioned enhancement of the nicotine reinforcer. Experimental and clinical psychopharmacology. vol 29. issue 4. 2021-10-25. PMID:32297785. |
overall, our results demonstrate that in addition to the multifaceted nature of nicotine stimulus that includes primary reinforcing effects, conditioned reinforcing effects, and reward enhancing effects, nicotine can also acquire additional reinforcing properties through associations with other rewards. |
2021-10-25 |
2023-08-13 |
rat |
| Christie D Fowler, Luis Tuesta, Paul J Kenn. Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice. Psychopharmacology. 2021-10-21. PMID:23958943. |
role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice. |
2021-10-21 |
2023-08-12 |
mouse |
| Christie D Fowler, Luis Tuesta, Paul J Kenn. Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice. Psychopharmacology. 2021-10-21. PMID:23958943. |
here, we investigated the role of α5* nachrs in the effects of nicotine on brain reward systems. |
2021-10-21 |
2023-08-12 |
mouse |
| Takeshi Isomura, Joji Suzuki, Toshiya Mura. Paradise Lost: The relationships between neurological and psychological changes in nicotine-dependent patients. Addiction research & theory. vol 22. issue 2. 2021-10-21. PMID:24719610. |
previous research using functional magnetic resonance imaging (fmri) has shown that while activation of the reward circuit (ventral striatum) appears in response to tobacco-related rewards in nicotine dependence, responses to rewards other than tobacco (e.g. |
2021-10-21 |
2023-08-13 |
Not clear |
| Zheng-Xiong X. Preclinical Pharmacology, Efficacy and Safety of Varenicline in Smoking Cessation and Clinical Utility in High Risk Patients. Drug, healthcare and patient safety. vol 2010. issue 2. 2021-10-20. PMID:21278851. |
mechanism studies suggest that the pleasurable effects of smoking are mediated predominantly by nicotine, which activates the brain reward system by activation of brain α(4)β(2) nicotinic acetylcholine receptors (nachrs). |
2021-10-20 |
2023-08-12 |
Not clear |
| Anjelica Cardenas, Shahrdad Lotfipou. Age- and Sex-Dependent Nicotine Pretreatment Effects on the Enhancement of Methamphetamine Self-Administration in Sprague-Dawley Rats. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2021-10-20. PMID:34669941. |
rodent studies have shown that nicotine exposure in early adolescence increases subsequent drug intake and reward. |
2021-10-20 |
2023-08-13 |
rat |
| Janna K Moen, Anna M Le. Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors. Frontiers in neuroscience. vol 15. 2021-10-09. PMID:34621155. |
sex differences in the nicotinic acetylcholine receptor system of rodents: impacts on nicotine and alcohol reward behaviors. |
2021-10-09 |
2023-08-13 |
Not clear |
| Janna K Moen, Anna M Le. Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors. Frontiers in neuroscience. vol 15. 2021-10-09. PMID:34621155. |
multiple lines of evidence show a profound effect of sex in many aspects of alcohol and nicotine reward, with women having more difficulty quitting smoking and showing a faster progression toward developing alcohol use disorder compared with men. |
2021-10-09 |
2023-08-13 |
Not clear |
| Janna K Moen, Anna M Le. Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors. Frontiers in neuroscience. vol 15. 2021-10-09. PMID:34621155. |
however, the majority of preclinical studies on the mechanisms of alcohol and nicotine reward behaviors utilize only male rodents, and thus our understanding of alcohol and nicotine neuropharmacology relies heavily on male data. |
2021-10-09 |
2023-08-13 |
Not clear |
| Janna K Moen, Anna M Le. Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors. Frontiers in neuroscience. vol 15. 2021-10-09. PMID:34621155. |
in this review, we summarize what is known about sex differences in rodent models of alcohol and nicotine reward behaviors with a focus on neuronal nachrs, highlighting exciting areas for future research. |
2021-10-09 |
2023-08-13 |
Not clear |
| Kathleen R McNealy, Margaret E Ramsay, Scott T Barrett, Rick A Bevin. Reward-enhancing effects of d-amphetamine and its interactions with nicotine were greater in female rats and persisted across schedules of reinforcement. Behavioural pharmacology. vol 32. issue 5. 2021-09-07. PMID:34010168. |
nicotine enhances the value of environmental stimuli and rewards, and reward enhancement can maintain nicotine consumption. |
2021-09-07 |
2023-08-13 |
human |
| Kathleen R McNealy, Margaret E Ramsay, Scott T Barrett, Rick A Bevin. Reward-enhancing effects of d-amphetamine and its interactions with nicotine were greater in female rats and persisted across schedules of reinforcement. Behavioural pharmacology. vol 32. issue 5. 2021-09-07. PMID:34010168. |
when d-amphetamine was coadministered with nicotine, we found an interaction effect on reward enhancement that persisted across schedules of reinforcement. |
2021-09-07 |
2023-08-13 |
human |
| Hailley Angelyn, Gregory C Loney, Paul J Meye. Nicotine Enhances Goal-Tracking in Ethanol and Food Pavlovian Conditioned Approach Paradigms. Frontiers in neuroscience. vol 15. 2021-09-07. PMID:34483813. |
however, we recently reported that nicotine can also enhance approach toward locations of reward delivery ("goal-tracking") triggered by ethanol-predictive stimuli when the location of ethanol delivery is non-static (i.e., a retractable sipper bottle). |
2021-09-07 |
2023-08-13 |
Not clear |
| Chao Wang, Shuyue Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Xiao Luo, Kaicheng Li, Qingze Zeng, Quanquan Gu, Hualiang Yu, Yihong Yang, Minming Zhan. Abnormal white matter tracts of insula in smokers. Brain imaging and behavior. vol 15. issue 4. 2021-09-06. PMID:32974850. |
nicotine addiction is characterized as a neural circuit dysfunction, particularly with regard to the alterations in central reward pathways. |
2021-09-06 |
2023-08-13 |
Not clear |
| Chao Wang, Shuyue Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Xiao Luo, Kaicheng Li, Qingze Zeng, Quanquan Gu, Hualiang Yu, Yihong Yang, Minming Zhan. Abnormal white matter tracts of insula in smokers. Brain imaging and behavior. vol 15. issue 4. 2021-09-06. PMID:32974850. |
the insula, a cortical region that is thought to play a central role in this reward circuitry, has been implicated in the maintenance of nicotine addiction. |
2021-09-06 |
2023-08-13 |
Not clear |
| Kenneth A Perkin. Acute nicotine reinforcement requires ability to discriminate the stimulus effects of nicotine. Experimental and clinical psychopharmacology. 2021-09-03. PMID:33119384. |
the second, more recent program focused on threshold doses for discrimination of nicotine by cigarette smoking, a program that was very difficult to do until the past decade, and how nicotine's self-reported "reward" and preference via choice behavior relate to its discriminability. |
2021-09-03 |
2023-08-13 |
Not clear |
| Zahra Ghasemzadeh, Maryam Sardari, Parastoo Javadi, Ameneh Rezayo. Expression analysis of hippocampal and amygdala CREB-BDNF signaling pathway in nicotine-induced reward under stress in rats. Brain research. vol 1741. 2021-09-01. PMID:32417176. |
interestingly, sub-chronic stress-induced increase of nicotine reward only decreased the hippocampal pcreb/creb ratio. |
2021-09-01 |
2023-08-13 |
rat |
| Zahra Ghasemzadeh, Maryam Sardari, Parastoo Javadi, Ameneh Rezayo. Expression analysis of hippocampal and amygdala CREB-BDNF signaling pathway in nicotine-induced reward under stress in rats. Brain research. vol 1741. 2021-09-01. PMID:32417176. |
acute stress-induced increase of nicotine reward increased bdnf levels in the hippocampus. |
2021-09-01 |
2023-08-13 |
rat |
| Zahra Ghasemzadeh, Maryam Sardari, Parastoo Javadi, Ameneh Rezayo. Expression analysis of hippocampal and amygdala CREB-BDNF signaling pathway in nicotine-induced reward under stress in rats. Brain research. vol 1741. 2021-09-01. PMID:32417176. |
in summary, the present study indicate that the alterations of the ratio of pcreb/creb and also the level of bdnf in the hippocampus may be critical for enhancing nicotine reward under stress condition. |
2021-09-01 |
2023-08-13 |
rat |
| Zahra Ghasemzadeh, Maryam Sardari, Parastoo Javadi, Ameneh Rezayo. Expression analysis of hippocampal and amygdala CREB-BDNF signaling pathway in nicotine-induced reward under stress in rats. Brain research. vol 1741. 2021-09-01. PMID:32417176. |
the evidence from this study suggests the distinct roles of the hippocampus and the amygdala in mediating nicotine reward under stress. |
2021-09-01 |
2023-08-13 |
rat |