| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Trinity I Russell, Mike J F Robinso. Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869950. |
effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. |
2020-01-09 |
2023-08-13 |
rat |
| Trinity I Russell, Mike J F Robinso. Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869950. |
however, it is unknown how nicotine or anxiety might contribute to cue and reward attraction, or promote disordered gambling behavior. |
2020-01-09 |
2023-08-13 |
rat |
| Trinity I Russell, Mike J F Robinso. Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869950. |
here, we found that nicotine enhanced attraction to the magazine under certain but not uncertain reward conditions, and increased cue-triggered behaviors. |
2020-01-09 |
2023-08-13 |
rat |
| Trinity I Russell, Mike J F Robinso. Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869950. |
conversely, in the progressive ratio task, exposure to uncertain conditions and nicotine enhanced motivation for reward, compared with certain conditions. |
2020-01-09 |
2023-08-13 |
rat |
| Trinity I Russell, Mike J F Robinso. Effects of nicotine exposure and anxiety on motivation for reward and gambling-like cues under reward uncertainty. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869950. |
these results suggest that nicotine may interact with both certain and uncertain reward conditions to increase cue-triggered behavior and enhance motivation for rewards, providing possible insight into the comorbid relationship between pathological gambling and tobacco use. |
2020-01-09 |
2023-08-13 |
rat |
| Juan Pablo Gonzalez-Gutierrez, Martin Hodar, Franco Viscarra, Pablo Paillali, Nicolás Guerra-Díaz, Hernán Pessoa-Mahana, Juan José Hernández-Morantes, Horacio Pérez-Sánchez, Isabel Bermúdez, Miguel Reyes-Parada, Patricio Iturriaga-Vásque. Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues. Molecules (Basel, Switzerland). vol 24. issue 15. 2020-01-02. PMID:31344816. |
neuronal α4β2 nicotinic acetylcholine receptors (nachrs) are ligand-gated ion channels (lgic) that have been implicated in nicotine addiction, reward, cognition, pain disorders, anxiety, and depression. |
2020-01-02 |
2023-08-13 |
Not clear |
| Michelle Ren, Shahrdad Lotfipou. Nicotine Gateway Effects on Adolescent Substance Use. The western journal of emergency medicine. vol 20. issue 5. 2019-12-30. PMID:31539325. |
in this review, we emphasize that the effects of nicotine are highly dependent on timing of exposure, with a dynamic interaction of nachrs with dopaminergic, endocannabinoid, and opioidergic systems to enhance general drug reward and reinforcement. |
2019-12-30 |
2023-08-13 |
Not clear |
| Giulia Donvito, Fabiana Piscitelli, Pretal Muldoon, Asti Jackson, Rosa Maria Vitale, Enrico D'Aniello, Catia Giordano, Bogna M Ignatowska-Jankowska, Mohammed A Mustafa, Francesca Guida, Gavin N Petrie, Linda Parker, Reem Smoum, Laura Sim-Selley, Sabatino Maione, Aron H Lichtman, M Imad Damaj, Vincenzo Di Marzo, Raphael Mechoula. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. vol 148. 2019-12-27. PMID:29567093. |
n-oleoyl-glycine reduces nicotine reward and withdrawal in mice. |
2019-12-27 |
2023-08-13 |
mouse |
| Giulia Donvito, Fabiana Piscitelli, Pretal Muldoon, Asti Jackson, Rosa Maria Vitale, Enrico D'Aniello, Catia Giordano, Bogna M Ignatowska-Jankowska, Mohammed A Mustafa, Francesca Guida, Gavin N Petrie, Linda Parker, Reem Smoum, Laura Sim-Selley, Sabatino Maione, Aron H Lichtman, M Imad Damaj, Vincenzo Di Marzo, Raphael Mechoula. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. vol 148. 2019-12-27. PMID:29567093. |
our respective in vitro and in vivo observations that olgly activated peroxisome proliferator-activated receptor alpha (ppar-α) and the ppar-α antagonist gw6471 prevented the olgly-induced reduction of nicotine cpp in mice suggests that this lipid acts as a functional ppar-α agonist to attenuate nicotine reward. |
2019-12-27 |
2023-08-13 |
mouse |
| Evangelia Liakoni, Kathryn C Edwards, Gideon St Helen, Natalie Nardone, Delia A Dempsey, Rachel F Tyndale, Neal L Benowit. Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence. Clinical pharmacology and therapeutics. vol 105. issue 3. 2019-12-19. PMID:30242831. |
blood nicotine concentrations, expired carbon monoxide, withdrawal/craving, and reward questionnaires were collected before/after smoking and during daytime abstinence. |
2019-12-19 |
2023-08-13 |
Not clear |
| Katja Baur, Arian Hach, Rick E Bernardi, Rainer Spanagel, Hilmar Bading, C Peter Bengtso. c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo. The Journal of comparative neurology. vol 526. issue 13. 2019-12-16. PMID:29888787. |
complex circuitry interconnecting dopaminergic and cholinergic regions of the midbrain and mesopontine tegmentum are critical for nicotine associated reward. |
2019-12-16 |
2023-08-13 |
mouse |
| Gavin N Petrie, Kiri L Wills, Fabiana Piscitelli, Reem Smoum, Cheryl L Limebeer, Erin M Rock, Ashlyn E Humphrey, Madeleine Sheppard-Perkins, Aron H Lichtman, Raphael Mechoulam, Vincenzo Di Marzo, Linda A Parke. Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats. Psychopharmacology. vol 236. issue 9. 2019-11-26. PMID:30993360. |
oleoyl glycine (olgly), a recently discovered fatty acid amide that is structurally similar to n- acylethanolamines, which include the endocannabinoid, anandamide (aea), as well as endogenous peroxisome proliferator-activated receptor alpha (pparα) agonists oleoylethanolamide (oea) and palmitoylethanolamide (pea), has been shown to interfere with nicotine reward and dependence in mice. |
2019-11-26 |
2023-08-13 |
mouse |
| Jed E Rose, Ozra Dehkordi, Kebreten F Manaye, Richard M Millis, Salman Ameri Cianaki, Annapurni Jayam-Trout. The Sensory Impact of Nicotine on Noradrenergic and Dopaminergic Neurons of the Nicotine Reward - Addiction Neurocircuitry. Journal of addiction research & therapy. vol 7. issue 2. 2019-11-20. PMID:27347434. |
the sensory impact of nicotine on noradrenergic and dopaminergic neurons of the nicotine reward - addiction neurocircuitry. |
2019-11-20 |
2023-08-13 |
mouse |
| Michael Euler, Ian T Baldwi. The chemistry of defense and apparency in the corollas ofNicotiana attenuata. Oecologia. vol 107. issue 1. 2019-11-20. PMID:28307197. |
similarly, nicotine, a broadly biocidal defense metabolite and an induced defense in vegetative and reproductive tissues, is also found in the headspace of flowers and is principally localized in the basal parts of the corolla below the attachment of the filaments and the nectar reward. |
2019-11-20 |
2023-08-13 |
Not clear |
| Liam J Nestor, Ella McCabe, Jennifer Jones, Luke Clancy, Hugh Garava. Smokers and ex-smokers have shared differences in the neural substrates for potential monetary gains and losses. Addiction biology. vol 23. issue 1. 2019-08-27. PMID:27943592. |
despite an increased understanding of nicotine addiction, there is a scarcity of research comparing the neural correlates of non-drug reward between smokers and ex-smokers. |
2019-08-27 |
2023-08-13 |
Not clear |
| Liam J Nestor, Ella McCabe, Jennifer Jones, Luke Clancy, Hugh Garava. Smokers and ex-smokers have shared differences in the neural substrates for potential monetary gains and losses. Addiction biology. vol 23. issue 1. 2019-08-27. PMID:27943592. |
similarly, examining the effects of previous chronic nicotine exposure during a period of extended abstinence may reveal whether there are neural correlates responsible for non-drug reward processing that are different from current smokers. |
2019-08-27 |
2023-08-13 |
Not clear |
| Liam J Nestor, Ella McCabe, Jennifer Jones, Luke Clancy, Hugh Garava. Smokers and ex-smokers have shared differences in the neural substrates for potential monetary gains and losses. Addiction biology. vol 23. issue 1. 2019-08-27. PMID:27943592. |
the results suggest that smoking may sensitize striato-orbitofrontal circuitry subserving motivational processes for loss avoidance and reward gain in nicotine addiction. |
2019-08-27 |
2023-08-13 |
Not clear |
| Marina Šagud, Ivona Šimunović Filipčić, Nenad Jakšić, Lucija Šimunić, Dejana Jezernik, Lucija Tudor, Zoran Madžarac, Ivana Stefanović, Biljana Kosanović Rajačić, Alma Mihaljević-Peleš, Bjanka Vuksan-Ćusa, Suzan Kudlek Mikulić, Nela Piva. Anhedonia in Schizophrenia: Mini-Review. Psychiatria Danubina. vol 31. issue Suppl 2. 2019-08-26. PMID:31158114. |
while gene-environment interactions affect reward circuity, anhedonia modulates clinical features, such as suicidality and nicotine consumption. |
2019-08-26 |
2023-08-13 |
human |
| Wuyi Liu, Kunkai S. A Review on the Receptor-ligand Molecular Interactions in the Nicotinic Receptor Signaling Systems. Pakistan journal of biological sciences : PJBS. vol 21. issue 2. 2019-08-07. PMID:30221881. |
understanding the cellular receptor-ligand interactions and molecular mechanisms between nachrs and ligands will lead to a better translational and therapeutic operations and outcomes for the prevention and treatment of nicotine addiction and other chronic drug addictions in the brain's reward circuitry. |
2019-08-07 |
2023-08-13 |
Not clear |
| Edmund A Griffin, Philippe A Melas, Royce Zhou, Yang Li, Peter Mercado, Kimberly A Kempadoo, Stacy Stephenson, Luca Colnaghi, Kathleen Taylor, Mei-Chen Hu, Eric R Kandel, Denise B Kande. Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5. Science advances. vol 3. issue 11. 2019-06-27. PMID:29109977. |
together, our findings suggest a shared mechanism of action for the gateway drugs alcohol and nicotine, and reveal a novel mechanism by which environmental factors may alter the epigenetic landscape of the reward system to increase vulnerability to cocaine addiction. |
2019-06-27 |
2023-08-13 |
rat |