| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Renee F Keller, Pinar Kanlikilicer, Andrei Dragomir, Yantao Fan, Yasemin M Akay, Metin Aka. Investigating the Effect of Perinatal Nicotine Exposure on Dopaminergic Neurons in the VTA Using miRNA Expression Profiles. IEEE transactions on nanobioscience. vol 16. issue 8. 2019-01-02. PMID:29364128. |
dopaminergic (da) neurons originating from the ventral tegmental area (vta) of the brain, which are stimulated by nicotine and other stimuli, are widely implicated in the natural reward pathway that is known to contribute to addiction. |
2019-01-02 |
2023-08-13 |
rat |
| Javier Íbias, Laura E O'Dell, Arbi Nazaria. Insulin dependent and independent normalization of blood glucose levels reduces the enhanced rewarding effects of nicotine in a rodent model of diabetes. Behavioural brain research. vol 351. 2018-12-18. PMID:29803655. |
it is presently unclear whether the enhanced nicotine reward observed in the diabetes models are mediated via an insulin or glucose mechanism. |
2018-12-18 |
2023-08-13 |
rat |
| D Baracchi, A Marples, A J Jenkins, A R Leitch, L Chittk. Nicotine in floral nectar pharmacologically influences bumblebee learning of floral features. Scientific reports. vol 7. issue 1. 2018-12-11. PMID:28512323. |
furthermore, after experiencing flowers containing nicotine in any tested concentration, increasing numbers of bumblebees stay more faithful to these flowers, even if they become a suboptimal choice in terms of reward. |
2018-12-11 |
2023-08-13 |
Not clear |
| Gofarana Wilar, Kusnandar Anggadiredja, Yasuharu Shinoda, Kohji Fukunag. Inhibition of Nicotine Dependence by Curcuminoid Is Associated with Reduced Acetylcholinesterase Activity in the Mouse Brain. Pharmacology. vol 102. issue 3-4. 2018-11-27. PMID:30099467. |
nicotine is a stimulatory component in tobacco that activates the central nervous system reward pathway and causes nicotine dependence. |
2018-11-27 |
2023-08-13 |
mouse |
| Valeria Lallai, Christie D Fowle. More Than Just Chillin': Interactive Effects of Menthol and Nicotine in Drug Reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 12. 2018-11-05. PMID:28553838. |
more than just chillin': interactive effects of menthol and nicotine in drug reward. |
2018-11-05 |
2023-08-13 |
Not clear |
| Charles Geier, Nicole Roberts, David Lydon-Stale. The Effects of Smoking Abstinence on Incentivized Spatial Working Memory. Substance use & misuse. vol 53. issue 1. 2018-10-29. PMID:29116867. |
while previous studies have demonstrated altered reward and wm function associated with nicotine exposure, little is known about the effects of abstinence on the joint function of these systems. |
2018-10-29 |
2023-08-13 |
Not clear |
| Teresa R Franklin, Kanchana Jagannathan, Nathan Hager, Zhuo Fang, Sihua Xu, Joyce Wong, Anna Rose Childress, John A Detre, Hengyi Rao, Reagan Wetheril. Brain substrates of early (4h) cigarette abstinence: Identification of treatment targets. Drug and alcohol dependence. vol 182. 2018-09-20. PMID:29172122. |
research indicates that overnight nicotine abstinence disrupts neural activity in the mesocorticolimbic reward network; however, less is known about the time course of abstinence-induced brain changes. |
2018-09-20 |
2023-08-13 |
Not clear |
| Ana C Dutra-Tavares, Juliana O Silva, André L Nunes-Freitas, Vinícius M S Guimarães, Ulisses C Araújo, Ellen P S Conceição, Egberto G Moura, Patrícia C Lisboa, Cláudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaça, Anderson Ribeiro-Carvalh. Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 65. 2018-09-05. PMID:29054611. |
maternal undernutrition during lactation alters nicotine reward and dopac/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nachrs upregulation. |
2018-09-05 |
2023-08-13 |
mouse |
| Ana C Dutra-Tavares, Juliana O Silva, André L Nunes-Freitas, Vinícius M S Guimarães, Ulisses C Araújo, Ellen P S Conceição, Egberto G Moura, Patrícia C Lisboa, Cláudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaça, Anderson Ribeiro-Carvalh. Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 65. 2018-09-05. PMID:29054611. |
particularly, undernutrition during lactation affects the acute locomotor response to nicotine during adolescence, but the reward effect of continued exposure to nicotine remains unknown. |
2018-09-05 |
2023-08-13 |
mouse |
| Bai-Bing Zhang, Jiu-Lin D. [The structure and function of habenula]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063110. |
it is considered as an emotion center and plays critical roles in regulating diverse types of emotion-related behaviors, including anxiety, fear, reward, depression, and nicotine withdrawal. |
2018-08-29 |
2023-08-13 |
zebrafish |
| Korinna Romero, Carter W Daniels, Cassandra D Gipson, Federico Sanabri. Suppressive and enhancing effects of nicotine on food-seeking behavior. Behavioural brain research. vol 339. 2018-08-07. PMID:29175447. |
these results suggest that (a) lower doses of nicotine enhance the reward value of food and/or food-associated stimuli, (b) higher doses of nicotine enhance motoric activity, and (c) ostensive sensitization effects of nicotine on behavior partially reflect a tolerance to its transient suppressive motoric effects. |
2018-08-07 |
2023-08-13 |
rat |
| Wanhong Zuo, Cheng Xiao, Ming Gao, F Woodward Hopf, Krešimir Krnjević, J Michael McIntosh, Rao Fu, Jie Wu, Alex Bekker, Jiang-Hong Y. Nicotine regulates activity of lateral habenula neurons via presynaptic and postsynaptic mechanisms. Scientific reports. vol 6. 2018-06-27. PMID:27596561. |
these results demonstrate the existence of diverse functional nachr subtypes at presynaptic and postsynaptic sites in lhb, through which nicotine could facilitate or inhibit lhb neuronal activity and thus contribute to nicotine aversion or reward. |
2018-06-27 |
2023-08-13 |
mouse |
| Yan-Xue Xue, Ya-Yun Chen, Li-Bo Zhang, Li-Qun Zhang, Geng-Di Huang, Shi-Chao Sun, Jia-Hui Deng, Yi-Xiao Luo, Yan-Ping Bao, Ping Wu, Ying Han, Bruce T Hope, Yavin Shaham, Jie Shi, Lin L. Selective Inhibition of Amygdala Neuronal Ensembles Encoding Nicotine-Associated Memories Inhibits Nicotine Preference and Relapse. Biological psychiatry. vol 82. issue 11. 2018-06-21. PMID:28648649. |
nicotine craving and relapse often occurs after reactivation of nicotine reward memories. |
2018-06-21 |
2023-08-13 |
rat |
| Yan-Xue Xue, Ya-Yun Chen, Li-Bo Zhang, Li-Qun Zhang, Geng-Di Huang, Shi-Chao Sun, Jia-Hui Deng, Yi-Xiao Luo, Yan-Ping Bao, Ping Wu, Ying Han, Bruce T Hope, Yavin Shaham, Jie Shi, Lin L. Selective Inhibition of Amygdala Neuronal Ensembles Encoding Nicotine-Associated Memories Inhibits Nicotine Preference and Relapse. Biological psychiatry. vol 82. issue 11. 2018-06-21. PMID:28648649. |
we recently developed a memory retrieval-reconsolidation interference procedure in which reactivating nicotine reward memories by acute exposure to nicotine (the unconditioned stimulus [ucs]) and then pharmacologically interfering with memory reconsolidation decreased relapse to nicotine seeking in rats and nicotine craving in smokers. |
2018-06-21 |
2023-08-13 |
rat |
| B M Shar. Basolateral amygdala and stress-induced hyperexcitability affect motivated behaviors and addiction. Translational psychiatry. vol 7. issue 8. 2018-05-03. PMID:28786979. |
in summary, bla is required to promote responding for natural reward and respond to second-order drug-conditioned cues; reinstate cue-dependent drug seeking; express stress-enhanced reacquisition of nicotine intake; and drive anxiety and fear. |
2018-05-03 |
2023-08-13 |
human |
| Chisayo Kozuka, Tadashi Kaname, Chigusa Shimizu-Okabe, Chitoshi Takayama, Masato Tsutsui, Masayuki Matsushita, Keiko Abe, Hiroaki Masuzak. Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice. Diabetologia. vol 60. issue 8. 2018-04-30. PMID:28528402. |
recent studies in humans and rodents have demonstrated that addiction to fats shares a common mechanism with addiction to alcohol, nicotine and narcotics in terms of a dysfunction of brain reward systems. |
2018-04-30 |
2023-08-13 |
mouse |
| Marsida Kallupi, Olivier Georg. Nicotine Vapor Method to Induce Nicotine Dependence in Rodents. Current protocols in neuroscience. vol 80. 2018-04-25. PMID:28678400. |
nicotine, the main addictive component of tobacco, induces potentiation of brain stimulation reward, increases locomotor activity, and induces conditioned place preference. |
2018-04-25 |
2023-08-13 |
Not clear |
| Helene L Philogene-Khalid, Steven J Simmons, John W Muschamp, Scott M Rawl. Effects of ceftriaxone on conditioned nicotine reward in rats. Behavioural pharmacology. vol 28. issue 6. 2018-04-16. PMID:28704277. |
effects of ceftriaxone on conditioned nicotine reward in rats. |
2018-04-16 |
2023-08-13 |
rat |
| Helene L Philogene-Khalid, Steven J Simmons, John W Muschamp, Scott M Rawl. Effects of ceftriaxone on conditioned nicotine reward in rats. Behavioural pharmacology. vol 28. issue 6. 2018-04-16. PMID:28704277. |
our study used two-chamber place conditioning to assess effects of ceftriaxone (ctx) on persistence of conditioned nicotine reward. |
2018-04-16 |
2023-08-13 |
rat |
| Helene L Philogene-Khalid, Steven J Simmons, John W Muschamp, Scott M Rawl. Effects of ceftriaxone on conditioned nicotine reward in rats. Behavioural pharmacology. vol 28. issue 6. 2018-04-16. PMID:28704277. |
our results suggest that ctx reduces persistence of conditioned nicotine reward and may be helpful for improving abstinence rates in a subset of treatment-seeking smokers. |
2018-04-16 |
2023-08-13 |
rat |