| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. |
brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. |
2018-04-10 |
2023-08-13 |
rat |
| Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. |
pre-conditioning intra-ca1 (0.5-4 µg/rat) or intra-medial prefrontal cortex (0.2-0.3 µg/rat) microinjection of mecamylamine (a non-selective nicotinic acetylcholine receptor antagonist) reversed acute stress-induced potentiation of nicotine reward as measured in the conditioned place preference paradigm. |
2018-04-10 |
2023-08-13 |
rat |
| Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. |
by contrast, pre-conditioning intra-basolateral amygdala microinjection of mecamylamine (4 µg/rat) potentiated the effects of acute stress on nicotine reward. |
2018-04-10 |
2023-08-13 |
rat |
| Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. |
our findings also showed that intra-ca1 or intra-medial prefrontal cortex, but not intra-basolateral amygdala, microinjection of mecamylamine (4 µg/rat) prevented the effect of sub-chronic stress on nicotine reward. |
2018-04-10 |
2023-08-13 |
rat |
| Maria E Secci, Alessia Auber, Leigh V Panlilio, Godfrey H Redhi, Eric B Thorndike, Charles W Schindler, Robert Schwarcz, Steven R Goldberg, Zuzana Justinov. Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28139681. |
as the effects of kyna on cannabinoid reward involve nicotinic receptors, in the present study we used rat and squirrel monkey models of reward and relapse to examine the possibility that enhancing kyna can counteract the effects of nicotine. |
2018-03-23 |
2023-08-13 |
rat |
| Maria E Secci, Alessia Auber, Leigh V Panlilio, Godfrey H Redhi, Eric B Thorndike, Charles W Schindler, Robert Schwarcz, Steven R Goldberg, Zuzana Justinov. Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28139681. |
in rats, ro 61-8048 reduced the ability of nicotine to induce dopamine release in the nucleus accumbens shell, a brain area believed to underlie nicotine reward. |
2018-03-23 |
2023-08-13 |
rat |
| Muzeyyen Ugur, Egemen Kaya, Oguz Gozen, Ersin O Koylu, Lutfiye Kanit, Aysegul Keser, Burcu Balka. Chronic nicotine-induced changes in gene expression of delta and kappa-opioid receptors and their endogenous ligands in the mesocorticolimbic system of the rat. Synapse (New York, N.Y.). vol 71. issue 9. 2018-03-01. PMID:28509375. |
delta and kappa opioid receptors (dor and kor, respectively) and their endogenous ligands, proenkephalin (penk) and prodynorphin (pdyn)-derived opioid peptides are proposed as important mediators of nicotine reward. |
2018-03-01 |
2023-08-13 |
rat |
| Carmen Huynh, Justine Fam, Serge H Ahmed, Kelly J Clemen. Rats quit nicotine for a sweet reward following an extensive history of nicotine use. Addiction biology. vol 22. issue 1. 2018-02-13. PMID:26374708. |
rats quit nicotine for a sweet reward following an extensive history of nicotine use. |
2018-02-13 |
2023-08-13 |
rat |
| Carmen Huynh, Justine Fam, Serge H Ahmed, Kelly J Clemen. Rats quit nicotine for a sweet reward following an extensive history of nicotine use. Addiction biology. vol 22. issue 1. 2018-02-13. PMID:26374708. |
this was followed by choice testing after a decrease in saccharin concentration (0.2-0%), omission of the fluid reward, an increase in nicotine concentration and following an extended nicotine self-administration history. |
2018-02-13 |
2023-08-13 |
rat |
| Carmen Huynh, Justine Fam, Serge H Ahmed, Kelly J Clemen. Rats quit nicotine for a sweet reward following an extensive history of nicotine use. Addiction biology. vol 22. issue 1. 2018-02-13. PMID:26374708. |
this was despite variations in reward concentrations, or after an extensive nicotine history. |
2018-02-13 |
2023-08-13 |
rat |
| Christopher A Arger, Sarah H Heil, Stacey C Sigmon, Jennifer W Tidey, Maxine L Stitzer, Diann E Gaalema, Hanna J Durand, Janice Y Bunn, Elizabeth K Ruggieri, Stephen T Higgin. Preliminary validity of the modified Cigarette Evaluation Questionnaire in predicting the reinforcing effects of cigarettes that vary in nicotine content. Experimental and clinical psychopharmacology. vol 25. issue 6. 2018-01-31. PMID:29251976. |
in phase 1 (five sessions), the mceq (satisfaction, psychological reward, enjoyment of respiratory tract sensations, craving reduction, aversion subscales) was administered following ad lib smoking of spectrum cigarettes and subscale differences scores were calculated by subtracting ratings of the 15.8 mg/g cigarette from ratings of the reduced nicotine content cigarettes. |
2018-01-31 |
2023-08-13 |
human |
| Ryan M Bastle, Natalie A Peartree, Julianna Goenaga, Kayla N Hatch, Angela Henricks, Samantha Scott, Lauren E Hood, Janet L Neisewande. Immediate early gene expression reveals interactions between social and nicotine rewards on brain activity in adolescent male rats. Behavioural brain research. vol 313. 2018-01-25. PMID:27435419. |
reward interactions were also found in the dorsolateral striatum, basolateral amygdala, and ventral tegmental area where nicotine alone attenuated ieg expression and social reward reversed this effect. |
2018-01-25 |
2023-08-13 |
rat |
| Xiaoli Qi, Lidia Guzhva, Zhihui Yang, Marcelo Febo, Zhiying Shan, Kevin K W Wang, Adriaan W Bruijnzee. Overexpression of CRF in the BNST diminishes dysphoria but not anxiety-like behavior in nicotine withdrawing rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27461514. |
the effect of nicotine withdrawal on brain reward function was investigated with an intracranial self-stimulation (icss) procedure. |
2018-01-18 |
2023-08-13 |
rat |
| Melissa J Guildford, Anthony V Sacino, Andrew R Tappe. Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the α6 subunit. Alcohol (Fayetteville, N.Y.). vol 57. 2018-01-03. PMID:27793544. |
nicotine, the addictive component of tobacco, activates nicotinic acetylcholine receptors (nachrs) containing the α6 subunit (α6* nachrs) in dopaminergic (daergic) neurons of the ventral tegmental area (vta), a region known to be crucial for drug reward. |
2018-01-03 |
2023-08-13 |
mouse |
| Rell L Parker, Heidi C O'Neill, Beverley M Henley, Charles R Wageman, Ryan M Drenan, Michael J Marks, Julie M Miwa, Sharon R Grady, Henry A Leste. Deletion of lynx1 reduces the function of α6* nicotinic receptors. PloS one. vol 12. issue 12. 2017-12-29. PMID:29206881. |
the α6 nicotinic acetylcholine receptor (nachr) subunit is an attractive drug target for treating nicotine addiction because it is present at limited sites in the brain including the reward pathway. |
2017-12-29 |
2023-08-13 |
mouse |
| Jason A Oliver, David E Evans, Merideth A Addicott, Geoffrey F Potts, Thomas H Brandon, David J Drobe. Nicotine Withdrawal Induces Neural Deficits in Reward Processing. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 19. issue 6. 2017-12-27. PMID:28371807. |
nicotine withdrawal induces neural deficits in reward processing. |
2017-12-27 |
2023-08-13 |
Not clear |
| Alyssa L Peechatka, Amy C Jane. Association Between Reward Reactivity and Drug Use Severity is Substance Dependent: Preliminary Evidence From the Human Connectome Project. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 19. issue 6. 2017-12-27. PMID:28486710. |
it also is possible that such a relationship is substance specific, as nicotine transiently increases reward system sensitivity while alcohol, another commonly used substance, does not. |
2017-12-27 |
2023-08-13 |
human |
| Alyssa L Peechatka, Amy C Jane. Association Between Reward Reactivity and Drug Use Severity is Substance Dependent: Preliminary Evidence From the Human Connectome Project. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 19. issue 6. 2017-12-27. PMID:28486710. |
as smokers may use nicotine to bolster nac reward function, we hypothesize that nac reactivity to reward will be related to volume of cigarette use, but not volume of alcohol use. |
2017-12-27 |
2023-08-13 |
human |
| Egemen Kaya, Oguz Gozen, Muzeyyen Ugur, Ersin O Koylu, Lutfiye Kanit, Burcu Balka. Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990424. |
we conclude that nicotine regulates cart expression in the mesocorticolimbic system and this regulation may play an important role in nicotine reward. |
2017-12-22 |
2023-08-13 |
rat |
| Hillel R Alpert, Israel T Agaku, Gregory N Connoll. A study of pyrazines in cigarettes and how additives might be used to enhance tobacco addiction. Tobacco control. vol 25. issue 4. 2017-12-20. PMID:26063608. |
tobacco product design features enhance abuse liability by (a) optimising the dynamic delivery of nicotine to central nervous system receptors, and affecting smokers' withdrawal symptoms, mood and behaviour; and (b) effecting conditioned learning, through sensory cues, including aroma, touch and visual stimulation, to create perceptions of pending nicotine reward. |
2017-12-20 |
2023-08-13 |
Not clear |