| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura H Corbit, Bernard W Ballein. The general and outcome-specific forms of Pavlovian-instrumental transfer are differentially mediated by the nucleus accumbens core and shell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 33. 2011-10-13. PMID:21849539. |
these results suggest that whereas the nac core mediates the general excitatory effects of reward-related cues, the nac shell mediates the effect of outcome-specific reward predictions on instrumental performance, and thereby serve to clarify reported discrepancies regarding the role of the nac core and shell in pit. |
2011-10-13 |
2023-08-12 |
rat |
| Alessandra Lintas, Ning Chi, Nicole M Lauzon, Stephanie F Bishop, Shervin Gholizadeh, Ninglei Sun, Huibing Tan, Steven R Laviolett. Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 31. 2011-10-11. PMID:21813678. |
using a combination of in vivo single-unit extracellular recording in the nac combined with behavioral pharmacology studies, we have identified a double dissociation in the functional roles of da d1 versus d2 receptor transmission in the bla, which depends on opiate exposure state; thus, in previously opiate-naive rats, blockade of intra-bla d1, but not d2, receptor transmission blocked the acquisition of associative opiate reward memory, measured in an unbiased conditioned place preference procedure. |
2011-10-11 |
2023-08-12 |
rat |
| Jessy John, Rohit Manchand. Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences. vol 36. issue 2. 2011-10-07. PMID:21654085. |
the nucleus accumbens (nac), a critical structure of the brain reward circuit, is implicated in normal goal-directed behaviour and learning as well as pathological conditions like schizophrenia and addiction. |
2011-10-07 |
2023-08-12 |
Not clear |
| Segev Barak, Sebastien Carnicella, Quinn V Yowell, Dorit Ro. Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734280. |
withdrawal from excessive alcohol intake is associated with a reduction in nac da levels, whereas drug-induced increases in nac da levels are associated with reward. |
2011-09-09 |
2023-08-12 |
rat |
| Matthew B Wilkinson, Caroline Dias, Jane Magida, Michelle Mazei-Robison, MaryKay Lobo, Pamela Kennedy, David Dietz, Herbert Covington, Scott Russo, Rachael Neve, Subroto Ghose, Carol Tamminga, Eric J Nestle. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 25. 2011-09-02. PMID:21697359. |
based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (dvl)-2, as being regulated in the nucleus accumbens (nac), a key brain reward region, in the mouse social defeat model of depression. |
2011-09-02 |
2023-08-12 |
mouse |
| Wei Wang, Dalong Sun, Bin Pan, Christopher J Roberts, Xinglai Sun, Cecilia J Hillard, Qing-song Li. Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 11. 2011-08-08. PMID:20664582. |
the nucleus accumbens (nac) is a critical component of the reward circuitry, and dysfunction of the nac may account for anhedonia and other symptoms of depression. |
2011-08-08 |
2023-08-12 |
mouse |
| Gabriele Hampp, Urs Albrech. The circadian clock and mood-related behavior. Communicative & integrative biology. vol 1. issue 1. 2011-07-14. PMID:19704445. |
in the mesolimbic dopaminergic reward circuit, including the ventral tegmental area (vta) and the ventral striatum/nucleus accumbens (nac) we found a positive influence of period 2 (per2) on transcriptional activation of maoa using mice mutant in the per2 gene. |
2011-07-14 |
2023-08-12 |
mouse |
| Viviana Trezza, Ruth Damsteegt, E J Marijke Achterberg, Louk J M J Vanderschure. Nucleus accumbens μ-opioid receptors mediate social reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525276. |
here, we studied the neural underpinnings of social reward by investigating the involvement of opioid neurotransmission in the nucleus accumbens (nac) in social play behavior, a highly rewarding social interaction in adolescent rats. |
2011-06-24 |
2023-08-12 |
rat |
| Colin M Stopper, Stan B Floresc. Contributions of the nucleus accumbens and its subregions to different aspects of risk-based decision making. Cognitive, affective & behavioral neuroscience. vol 11. issue 1. 2011-06-21. PMID:21264647. |
inactivation of the nac or the shell subregion also slightly reduced preference for larger rewards on a reward magnitude discrimination. |
2011-06-21 |
2023-08-12 |
rat |
| Jeremy J Day, Joshua L Jones, Regina M Carell. Nucleus accumbens neurons encode predicted and ongoing reward costs in rats. The European journal of neuroscience. vol 33. issue 2. 2011-06-01. PMID:21198983. |
here, neuronal activity in the rat nac was monitored using multi-neuron electrophysiology during two cost-based decision tasks in which either reward effort or reward delay was manipulated. |
2011-06-01 |
2023-08-12 |
rat |
| Barbara K A Onishi, Gilberto F Xavie. Negative anticipatory contrast: does it involve anticipation of an impending reward? Behavioural processes. vol 86. issue 2. 2011-05-27. PMID:21187128. |
the nac has been interpreted as resulting from anticipation of the impending preferred reward and its comparison with the currently available first reward [flaherty, c.f., rowan, g.a., 1985. |
2011-05-27 |
2023-08-12 |
Not clear |
| Kyohei Mori, Juhyon Kim, Kazuo Sasak. Electrophysiological effects of orexin-B and dopamine on rat nucleus accumbens shell neurons in vitro. Peptides. vol 32. issue 2. 2011-05-05. PMID:21055430. |
the mesolimbic dopamine (da) pathway that projects into the nucleus accumbens (nac) from the ventral tegmental area is deeply involved in the neural mechanisms underlying reward, drug abuse and motivation. |
2011-05-05 |
2023-08-12 |
rat |
| S L Sánchez-Serrano, S L Cruz, M Lama. Repeated toluene exposure modifies the acetylation pattern of histones H3 and H4 in the rat brain. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21146589. |
in order to decipher whether repeated toluene exposure could mediate epigenetic changes in the rat brain, we here analyzed the acetylation pattern of histones h3 and h4 in three brain areas that have been previously associated to substance abuse reward pathways: the nucleus accumbens (nac), the ventral tegmental area (vta) and the central amygdala (cea). |
2011-04-29 |
2023-08-12 |
rat |
| Atsumi Nitta, Yoko Hibi, Yoshiaki Miyamoto, Toshitaka Nabeshim. [Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 45. issue 6. 2011-04-26. PMID:21387608. |
piccolo downexpression by antisense technique augmented meth-induced behavioral sensitization, conditioned reward and synaptic dopamine accumulation in nac. |
2011-04-26 |
2023-08-12 |
mouse |
| E C Muly, M Maddox, Z U Kha. Distribution of D1 and D5 dopamine receptors in the primate nucleus accumbens. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600664. |
the d1 family of dopamine receptors (d1r) play a critical role in modulating reward in the nucleus accumbens (nac). |
2011-04-18 |
2023-08-12 |
Not clear |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
here, we report that cocaine dramatically and dynamically alters heterochromatic histone h3 lysine 9 trimethylation (h3k9me3) in the nucleus accumbens (nac), a key brain reward region. |
2011-04-14 |
2023-08-12 |
Not clear |
| Stuart L Gibb, Jerome Jeanblanc, Segev Barak, Quinn V Yowell, Rami Yaka, Dorit Ro. Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 6. 2011-03-25. PMID:21307254. |
increase in da levels in the nac is closely associated with reward-related behaviors, and overexpression of ca-lyn in the vta of mice led to an attenuation of alcohol reward, measured in a conditioned place preference paradigm. |
2011-03-25 |
2023-08-12 |
mouse |
| Xiao-Qing Peng, Zheng-Xiong Xi, Xia Li, Krista Spiller, Jie Li, Lauren Chun, Kuo-Ming Wu, Mark Froimowitz, Eliot L Gardne. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 13. 2011-03-03. PMID:20827272. |
systemic administration of 31,345 produced long-lasting enhancement of electrical brain-stimulation reward (bsr) and extracellular nucleus accumbens (nac) dopamine (da). |
2011-03-03 |
2023-08-12 |
Not clear |
| Mark C Moffett, Jane Song, Michael J Kuha. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506412. |
previously, our laboratory demonstrated that injections of cart peptide (cart 55-102) into the nucleus accumbens (nac) attenuated both cocaine- and dopamine-induced increases in locomotor activity (lma), and attenuated cocaine reward as well. |
2011-02-04 |
2023-08-12 |
rat |
| George A Rogge, Li-Ling Shen, Michael J Kuha. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter. Brain research. vol 1344. 2011-01-10. PMID:20451507. |
both over expression of cyclic amp response element binding protein (creb) in the nucleus accumbens (nac), and intra-accumbal injection of cocaine- and amphetamine-regulated transcript (cart) peptides, have been shown to decrease cocaine reward. |
2011-01-10 |
2023-08-12 |
rat |