| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Negar Baharlouei, Abdolrahman Sarihi, Marzieh Moradi, Shahram Zarrabian, Abbas Haghparas. Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced conditioned place preference in rats. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29462112. |
the nucleus accumbens (nac), which is one of the important areas involved in the reward circuitry, also expresses these receptors. |
2019-07-31 |
2023-08-13 |
rat |
| Jennifer Albertz, Gretha J Boersma, Kellie L Tamashiro, Timothy H Mora. The effects of scheduled running wheel access on binge-like eating behavior and its consequences. Appetite. vol 126. 2019-07-31. PMID:29654852. |
additionally, within both groups, the gene expression of the d2r and oprm1 in the nac and the vta were altered suggesting that the reward system was stimulated by both the bingeing behavior and the running wheel activity. |
2019-07-31 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Fariba Khodagholi, Fatemeh Shaerzadeh, Abbas Haghparas. Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats. Brain research bulletin. vol 142. 2019-07-30. PMID:30170186. |
brain reward and motivation circuit begin from the ventral tegmental area (vta) that its dopaminergic terminals project to various regions of the brain including the nucleus accumbens (nac). |
2019-07-30 |
2023-08-13 |
rat |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
in particular, areas such as the ventral tegmental area (vta), nucleus accumbens (nac), and ventral pallidum (vp) are thought to generally promote reward, with the medial prefrontal cortex (mpfc) providing top-down control of reward seeking. |
2019-06-24 |
2023-08-13 |
Not clear |
| David A Seminowicz, Bethany Remeniuk, Samuel R Krimmel, Michael T Smith, Frederick S Barrett, Andreas B Wulff, Andrew J Furman, Stephan Geuter, Martin A Lindquist, Michael R Irwin, Patrick H Fina. Pain-related nucleus accumbens function: modulation by reward and sleep disruption. Pain. vol 160. issue 5. 2019-06-12. PMID:30753171. |
the nucleus accumbens (nac) has been implicated in sleep, reward, and pain modulation, but the relationship between these functional roles is unclear. |
2019-06-12 |
2023-08-13 |
human |
| Mahsaneh Vatankhah, Abdolrahman Sarihi, Alireza Komaki, Siamak Shahidi, Abbas Haghparas. AMN082-a metabotropic glutamate receptor type 7 allosteric agonist in the NAc facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. vol 140. 2019-06-04. PMID:29605484. |
nucleus accumbens (nac) plays a primary role in opioid reward. |
2019-06-04 |
2023-08-13 |
rat |
| Mahsaneh Vatankhah, Abdolrahman Sarihi, Alireza Komaki, Siamak Shahidi, Abbas Haghparas. AMN082-a metabotropic glutamate receptor type 7 allosteric agonist in the NAc facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. vol 140. 2019-06-04. PMID:29605484. |
previous studies have shown the extensive distributions of the different types of mglurs, including mglur7, in regions that are involved in opioid reward, such as nac. |
2019-06-04 |
2023-08-13 |
rat |
| María S García-Gutiérrez, Francisco Navarrete, Jorge Laborda, Jorge Manzanare. Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice. Biochemical pharmacology. vol 158. 2019-06-03. PMID:30268817. |
quantitative real time polymerase chain reaction (qpcr) studies were carried out to evaluate alterations in targets closely related to da neurotransmission in the reward system, tyrosine hydroxylase (th) in the ventral tegmental area (vta), and μ-opioid receptor (oprm1) in the nucleus accumbens (nac). |
2019-06-03 |
2023-08-13 |
mouse |
| Stan B Floresco, David R Montes, Maric M T Tse, Mieke van Holstei. Differential Contributions of Nucleus Accumbens Subregions to Cue-Guided Risk/Reward Decision Making and Implementation of Conditional Rules. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29348192. |
the nucleus accumbens (nac) is a key node within corticolimbic circuitry for guiding action selection and cost/benefit decision making in situations involving reward uncertainty. |
2019-05-20 |
2023-08-13 |
rat |
| Stan B Floresco, David R Montes, Maric M T Tse, Mieke van Holstei. Differential Contributions of Nucleus Accumbens Subregions to Cue-Guided Risk/Reward Decision Making and Implementation of Conditional Rules. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29348192. |
these data highlight distinct contributions for nac subregions in decision making and reward seeking guided by discriminative stimuli. |
2019-05-20 |
2023-08-13 |
rat |
| b' Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Gra\\xc5\\xbcyna Lietzau, Aleksandra Steliga, Ewelina Czuba, Beata Ludkiewicz, Monika Wa\\xc5\\x9bkow, Jan H Spodnik, Janusz Mory\\xc5\\x9. Nicotine-induced CREB and DeltaFosB activity is modified by caffeine in the brain reward system of the rat. Journal of chemical neuroanatomy. vol 88. 2019-05-14. PMID:29100904.' |
we aimed at determining the effect of caffeine and nicotine, applied separately or simultaneously, on activation of six structures of the brain reward system: nucleus accumbens (nac), ventral tegmental area (vta), amygdala (amg), hippocampus (hip), medial prefrontal cortex (mpfr) and dorsal striatum (cdp) in the adult male wistar rats. |
2019-05-14 |
2023-08-13 |
rat |
| Benjamin P Gold, Ernest Mas-Herrero, Yashar Zeighami, Mitchel Benovoy, Alain Dagher, Robert J Zatorr. Musical reward prediction errors engage the nucleus accumbens and motivate learning. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 8. 2019-05-01. PMID:30728301. |
these results demonstrate that music can act as a reward, driving learning and eliciting rpes in the nac, a hub of reward- and music enjoyment-related activity. |
2019-05-01 |
2023-08-13 |
human |
| Zahra Farzinpour, Zahra Taslimi, Ronak Azizbeigi, Saeideh Karimi-Haghighi, Abbas Haghparas. Involvement of orexinergic receptors in the nucleus accumbens, in the effect of forced swim stress on the reinstatement of morphine seeking behaviors. Behavioural brain research. vol 356. 2019-04-16. PMID:30195020. |
also, it has been indicated that orexinergic system activates the mesolimbic dopamine projecting neurons to the nac and promotes the development of reward in rodents. |
2019-04-16 |
2023-08-13 |
rat |
| Zahra Farzinpour, Zahra Taslimi, Ronak Azizbeigi, Saeideh Karimi-Haghighi, Abbas Haghparas. Involvement of orexinergic receptors in the nucleus accumbens, in the effect of forced swim stress on the reinstatement of morphine seeking behaviors. Behavioural brain research. vol 356. 2019-04-16. PMID:30195020. |
it seems that oxr in the nac may be involved in reward and could play an important role in the effect of stress on reinstatement of morphine-seeking behaviors in this area. |
2019-04-16 |
2023-08-13 |
rat |
| Chia-Yen Wu, Yi-Lin Tsai, Chung-Pin Hsieh, Tsui Chin Wang, Ming-Huan Chan, Hwei-Hsien Che. Attenuation of toluene-induced brain stimulation reward enhancement and behavioral disturbances by N-acetylcysteine in mice. Toxicology. vol 408. 2019-04-11. PMID:29935984. |
the present study examined whether nac is capable of attenuating the toluene-induced brain stimulation reward enhancement and behavioral manifestations. |
2019-04-11 |
2023-08-13 |
mouse |
| Chia-Yen Wu, Yi-Lin Tsai, Chung-Pin Hsieh, Tsui Chin Wang, Ming-Huan Chan, Hwei-Hsien Che. Attenuation of toluene-induced brain stimulation reward enhancement and behavioral disturbances by N-acetylcysteine in mice. Toxicology. vol 408. 2019-04-11. PMID:29935984. |
these results indicate that nac could prevent toluene-induced reward facilitation and behavioral disturbances and its beneficial effects, at least for cognitive function and social interaction, are associated with activation of the xct and mglur2/3. |
2019-04-11 |
2023-08-13 |
mouse |
| Jinxu Liu, Pauravi J Gandhi, Ratnamala Pavuluri, Gajanan P Shelkar, Shashank M Dravi. Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens. Translational psychiatry. vol 8. issue 1. 2019-04-01. PMID:30315226. |
recent neuroanatomical studies have demonstrated enriched expression of glud1 in the nac but its role in reward behavior, msn function, and drug-induced plasticity remains unknown. |
2019-04-01 |
2023-08-13 |
mouse |
| Katayoun Sedaghat, Zahra Yousefian, Abbas Ali Vafaei, Ali Rashidy-Pour, Houman Parsaei, Ali Khaleghian, Sara Choobda. Mesolimbic dopamine system and its modulation by vitamin D in a chronic mild stress model of depression in the rat. Behavioural brain research. vol 356. 2019-03-22. PMID:30144460. |
depression, a common mood disorder, involves anhedonia and defects in reward circuits and mesolimbic dopamine transmission in the striatum and nucleus accumbens (nac). |
2019-03-22 |
2023-08-13 |
rat |
| M E Cahill, D M Walker, A M Gancarz, Z J Wang, C K Lardner, R C Bagot, R L Neve, D M Dietz, E J Nestle. The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling. Molecular psychiatry. vol 23. issue 6. 2019-03-18. PMID:28555077. |
the nucleus accumbens (nac) is a primary brain reward region composed predominantly of medium spiny neurons (msns). |
2019-03-18 |
2023-08-13 |
Not clear |
| Amanda C Burton, Gregory B Bissonette, Daniela Vazquez, Elyse M Blume, Maria Donnelly, Kendall C Heatley, Abhishek Hinduja, Matthew R Roesc. Previous cocaine self-administration disrupts reward expectancy encoding in ventral striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 12. 2019-03-11. PMID:29728645. |
the nucleus accumbens core (nac) is important for integrating and providing information to downstream areas about the timing and value of anticipated reward. |
2019-03-11 |
2023-08-13 |
rat |