| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michelle Corkrum, Ana Covelo, Justin Lines, Luigi Bellocchio, Marc Pisansky, Kelvin Loke, Ruth Quintana, Patrick E Rothwell, Rafael Lujan, Giovanni Marsicano, Eduardo D Martin, Mark J Thomas, Paulo Kofuji, Alfonso Araqu. Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity. Neuron. vol 105. issue 6. 2020-07-14. PMID:31954621. |
we show that in freely behaving mice, astrocytes in the nucleus accumbens (nac), a key reward center in the brain, respond with ca |
2020-07-14 |
2023-08-13 |
mouse |
| S Gallegos, B Muñoz, A Araya, L G Aguay. High ethanol sensitive glycine receptors regulate firing in D1 medium spiny neurons in the nucleus accumbens. Neuropharmacology. vol 160. 2020-07-08. PMID:31521620. |
these results indicate that glyrs present in d1(+) msns are sensitive to low concentrations of ethanol, and that potentiation of this inhibitory current regulates the activation of nac, acting as a homeostatic signal that would prevent over-activation of the reward system when drugs like ethanol are consumed. |
2020-07-08 |
2023-08-13 |
Not clear |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (nac) shell and increasing nac shell bdnf is sufficient to enhance ethanol reward in naïve wistar rats. |
2020-06-30 |
2023-08-13 |
rat |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
the concluding experiment evaluated the effect of nac shell pretreatment with bdnf on etoh reward utilizing icsa within that region. |
2020-06-30 |
2023-08-13 |
rat |
| Lei Yuan, Yan-Nong Dou, Yan-Gang Su. Topography of Reward and Aversion Encoding in the Mesolimbic Dopaminergic System. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 33. 2020-06-22. PMID:31217328. |
here, we report that the encoding of reward and aversion by the da system in the nac is tightly associated with its anatomical location. |
2020-06-22 |
2023-08-13 |
Not clear |
| Michael A Benneyworth, Matthew C Hearing, Anders J Asp, Aric Madayag, Anna E Ingebretson, Clare E Schmidt, Keelia A Silvis, Erin B Larson, Stephanie R Ebner, Mark J Thoma. Synaptic Depotentiation and mGluR5 Activity in the Nucleus Accumbens Drive Cocaine-Primed Reinstatement of Place Preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 24. 2020-06-12. PMID:30948476. |
the nac serves as a critical substrate for reward and motivated behavior, in part due to alterations in excitatory synaptic strength within cortical-accumbens pathways. |
2020-06-12 |
2023-08-13 |
mouse |
| Yuan-Hao Chen, Bon-Jour Lin, Tsung-Hsun Hsieh, Tung-Tai Kuo, Jonathan Miller, Yu-Ching Chou, Eagle Yi-Kung Huang, Barry J Hoffe. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell transplantation. vol 28. issue 3. 2020-04-30. PMID:29807460. |
differences between phasic and tonic release associated with nicotine desensitization may underlie processing of reward signals in the nac shell, and this may have major implications for addictive behavior. |
2020-04-30 |
2023-08-13 |
rat |
| Alexander Gómez-A, Tatiana A Shnitko, Haley M Barefoot, Eleanor L Brightbill, Leslie A Sombers, Saleem M Nicola, Donita L Robinso. Local μ-Opioid Receptor Antagonism Blunts Evoked Phasic Dopamine Release in the Nucleus Accumbens of Rats. ACS chemical neuroscience. vol 10. issue 4. 2020-04-24. PMID:30388365. |
these findings demonstrate profound local control of dopamine release by mors within the nac core, which has implications for regulation of reward processing. |
2020-04-24 |
2023-08-13 |
rat |
| Daniel Vallöf, Aimilia Lydia Kalafateli, Elisabet Jerlha. Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents. Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771711. |
we therefore evaluated the effects of bilateral infusion of the glp-1r agonist exendin-4 (ex4) into nac shell, anterior (avta), posterior (pvta) or ldtg on the acute alcohol-induced locomotor stimulation and memory of alcohol reward in the conditioned place preference (cpp) model in mice, as well as on alcohol intake in rats consuming high amounts of alcohol for 12 weeks. |
2020-04-23 |
2023-08-13 |
mouse |
| Daniel Vallöf, Aimilia Lydia Kalafateli, Elisabet Jerlha. Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents. Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771711. |
ex4 into the nac shell blocks alcohol-induced locomotor stimulation and memory of alcohol reward as well as decreases alcohol intake. |
2020-04-23 |
2023-08-13 |
mouse |
| Pan Zhang, Laura S Moye, Bruce R Southey, Isaac Dripps, Jonathan V Sweedler, Amynah Pradhan, Sandra L Rodriguez-Za. Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31129808. |
using rna-seq profiles, gene networks were inferred in the trigeminal ganglia (tg), a central nervous system region associated with pain signaling, and in the nucleus accumbens (nac), a region associated with reward dependency. |
2020-04-06 |
2023-08-13 |
mouse |
| Julianna Kardos, Árpád Dobolyi, Zsolt Szabó, Ágnes Simon, Guillaume Lourmet, Miklós Palkovits, László Héj. Molecular Plasticity of the Nucleus Accumbens Revisited-Astrocytic Waves Shall Rise. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31134458. |
part of the ventral striatal division, the nucleus accumbens (nac) drives the circuit activity of an entire macrosystem about reward like a "flagship," signaling and leading diverse conducts. |
2020-04-06 |
2023-08-13 |
Not clear |
| Marielena Sosa, Hannah R Joo, Loren M Fran. Dorsal and Ventral Hippocampal Sharp-Wave Ripples Activate Distinct Nucleus Accumbens Networks. Neuron. vol 105. issue 4. 2020-03-30. PMID:31864947. |
both dorsal and ventral hippocampus (dh and vh) project to the nac, but it remains unknown whether dh and vh act in concert or separately to engage nac representations related to space and reward. |
2020-03-30 |
2023-08-13 |
rat |
| Marielena Sosa, Hannah R Joo, Loren M Fran. Dorsal and Ventral Hippocampal Sharp-Wave Ripples Activate Distinct Nucleus Accumbens Networks. Neuron. vol 105. issue 4. 2020-03-30. PMID:31864947. |
these temporally and anatomically separable hippocampal-nac interactions point to distinct channels of mnemonic processing in the nac, with the dh-nac channel specialized for spatial task and reward information. |
2020-03-30 |
2023-08-13 |
rat |
| Stéphanie Trouche, Vadim Koren, Natalie M Doig, Tommas J Ellender, Mohamady El-Gaby, Vítor Lopes-Dos-Santos, Hayley M Reeve, Pavel V Perestenko, Farid N Garas, Peter J Magill, Andrew Sharott, David Dupre. A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space. Cell. vol 176. issue 6. 2020-01-06. PMID:30773318. |
this tripartite cross-circuit motif supports spatial appetitive memory and associated nac assemblies, being independent of dorsal subiculum and dispensable for both spatial novelty detection and reward seeking. |
2020-01-06 |
2023-08-13 |
mouse |
| Elizabeth B Smedley, Alyssa DiLeo, Kyle S Smit. Circuit directionality for motivation: Lateral accumbens-pallidum, but not pallidum-accumbens, connections regulate motivational attraction to reward cues. Neurobiology of learning and memory. vol 162. 2019-12-27. PMID:31096040. |
the nac lateral shell (naclsh) is a distinct and understudied subdivision of the nac, and its contribution to the process by which reward cues acquire value remains unclear. |
2019-12-27 |
2023-08-13 |
Not clear |
| Jennifer A Martin, Craig T Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang, Pedro H Gobira, Andrew F Stewart, Jay Zhang, Kyra Erias, Justin N Siemian, Devin Hagarty, Lauren E Mueller, Rachael L Neve, Jun-Xu Li, Ramesh Chandra, Karen C Dietz, Mary Kay Lobo, Amy M Gancarz, Zhen Yan, David M Diet. A novel role for the actin-binding protein drebrin in regulating opiate addiction. Nature communications. vol 10. issue 1. 2019-12-23. PMID:31515501. |
persistent transcriptional and morphological events in the nucleus accumbens (nac) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. |
2019-12-23 |
2023-08-13 |
Not clear |
| Bárbara Coimbra, Carina Soares-Cunha, Nivaldo A P Vasconcelos, Ana Verónica Domingues, Sónia Borges, Nuno Sousa, Ana João Rodrigue. Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors. Nature communications. vol 10. issue 1. 2019-12-23. PMID:31515512. |
the laterodorsal tegmentum (ldt) is associated with reward considering that it modulates vta neuronal activity, but recent anatomical evidence shows that the ldt also directly projects to nucleus accumbens (nac). |
2019-12-23 |
2023-08-13 |
mouse |
| Katherine G Warthen, Benjamin Sanford, Kendal Walker, Keith G Jones, Mike Angstadt, Chandra Sripada, David Goldman, Jon-Kar Zubieta, Robert C Welsh, Margit Burmeister, Brian J Micke. Neuropeptide Y and representation of salience in human nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 3. 2019-12-18. PMID:30337638. |
studies in rodent models have also demonstrated that npy elicits reward behaviors through its action in the nucleus accumbens (nac), but the impact of npy on the human nac is largely unexplored. |
2019-12-18 |
2023-08-13 |
human |
| Brandon D Turner, Daniel T Kashima, Kevin M Manz, Carrie A Grueter, Brad A Gruete. Synaptic Plasticity in the Nucleus Accumbens: Lessons Learned from Experience. ACS chemical neuroscience. vol 9. issue 9. 2019-12-11. PMID:29280617. |
as a key node in the reward pathway, the nucleus accumbens (nac) is important for determining motivation-to-action outcomes. |
2019-12-11 |
2023-08-13 |
Not clear |