| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yangpan Ou, Qinji Su, Feng Liu, Yudan Ding, Jindong Chen, Zhikun Zhang, Jingping Zhao, Wenbin Gu. Increased Nucleus Accumbens Connectivity in Resting-State Patients With Drug-Naive, First-Episode Somatization Disorder. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31474890. |
the nucleus accumbens (nac) plays an important role in the reward circuit, and abnormal regional activities of the reward circuit have been reported in various psychiatric disorders including somatization disorder (sd). |
2020-10-01 |
2023-08-13 |
Not clear |
| Yangpan Ou, Qinji Su, Feng Liu, Yudan Ding, Jindong Chen, Zhikun Zhang, Jingping Zhao, Wenbin Gu. Increased Nucleus Accumbens Connectivity in Resting-State Patients With Drug-Naive, First-Episode Somatization Disorder. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31474890. |
the findings reveal that patients with sd have increased nac connectivity with the frontal regions of the reward circuit. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kenneth Blum, Marcelo Febo, Claudia Fahlke, Trevor Archer, U Berggren, Zsolt Demetrovics, Kristina Dushaj, Rajendra D Badgaiya. Hypothesizing Balancing Endorphinergic and Glutaminergic Systems to Treat and Prevent Relapse to Reward Deficiency Behaviors: Coupling D-Phenylalanine and N-Acetyl-L-Cysteine (NAC) as a Novel Therapeutic Modality. Clinical medical reviews and case reports. vol 2. issue 8. 2020-09-30. PMID:26900600. |
hypothesizing balancing endorphinergic and glutaminergic systems to treat and prevent relapse to reward deficiency behaviors: coupling d-phenylalanine and n-acetyl-l-cysteine (nac) as a novel therapeutic modality. |
2020-09-30 |
2023-08-13 |
Not clear |
| Liang Gong, Cancan He, Yingying Yin, Hui Wang, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Zhijun Zhang, Chunming Xi. Mediating Role of the Reward Network in the Relationship between the Dopamine Multilocus Genetic Profile and Depression. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28959185. |
multivariate linear regression analysis was employed to measure the effects of disease and multilocus genetic profile scores (mgps) on the reward network, which was constructed using the nucleus accumbens (nac) functional connectivity (nafc) network. |
2020-09-30 |
2023-08-13 |
human |
| Anze Testen, Marian T Sepulveda-Orengo, Christiann H Gaines, Kathryn J Reissne. Region-Specific Reductions in Morphometric Properties and Synaptic Colocalization of Astrocytes Following Cocaine Self-Administration and Extinction. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30147645. |
however, it is unknown whether these cocaine-dependent changes in astrocytes are ubiquitous throughout the brain's reward circuitry, or represent specific adaptations within the nac. |
2020-09-30 |
2023-08-13 |
rat |
| Kellie S Gross, Kelsey M Moore, Robert L Meisel, Paul G Mermelstei. mGluR5 Mediates Dihydrotestosterone-Induced Nucleus Accumbens Structural Plasticity, but Not Conditioned Reward. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30515075. |
a commonality between gonadal hormones and drugs of abuse is that they both impact the neurocircuitry of reward, including the regulation of structural plasticity in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
rat |
| Robert Hitzemann, Ovidiu D Iancu, Cheryl Reed, Harue Baba, Denesa R Lockwood, Tamara J Phillip. Regional Analysis of the Brain Transcriptome in Mice Bred for High and Low Methamphetamine Consumption. Brain sciences. vol 9. issue 7. 2020-09-30. PMID:31262025. |
three brain reward circuitry regions were explored, the nucleus accumbens (nac), prefrontal cortex (pfc), and ventral midbrain (vmb). |
2020-09-30 |
2023-08-13 |
mouse |
| Ann Mary Iturra-Mena, Marcelo Aguilar-Rivera, Marcia Arriagada-Solimano, Catherine Pérez-Valenzuela, Pablo Fuentealba, Alexies Dagnino-Subiabr. Impact of Stress on Gamma Oscillations in the Rat Nucleus Accumbens During Spontaneous Social Interaction. Frontiers in behavioral neuroscience. vol 13. 2020-09-30. PMID:31354444. |
social behavior is modulated by the reward system, and gamma oscillations in the nucleus accumbens (nac) seem to be associated with reward processing. |
2020-09-30 |
2023-08-13 |
rat |
| ChengPeng Yu, XiaoYan Zhou, Qiang Fu, QingHua Peng, Ki-Wan Oh, ZhenZhen H. A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28860971. |
cocaine- and amphetamine-regulated transcript (cart) peptides are neuropeptides that are expressed in brain regions associated with reward, such as the nucleus accumbens (nac), and play a role in cocaine reward. |
2020-09-29 |
2023-08-13 |
Not clear |
| Haocheng Zhou, Erik Martinez, Harvey H Lin, Runtao Yang, Jahrane Antonio Dale, Kevin Liu, Dong Huang, Jing Wan. Inhibition of the Prefrontal Projection to the Nucleus Accumbens Enhances Pain Sensitivity and Affect. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30150924. |
recent studies show that activation of the projections from the pfc to the nucleus accumbens (nac), an important pathway in the brain's reward circuitry, can produce inhibition of both sensory and affective components of pain. |
2020-09-29 |
2023-08-13 |
rat |
| Haley N Harris, Yuan B Pen. Evidence and explanation for the involvement of the nucleus accumbens in pain processing. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638081. |
the nucleus accumbens (nac) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
recently, we discovered an association between genetic vulnerability to ma-taking and increased expression of the glutamate receptor scaffolding protein homer2 within both the shell and core subregions of the nucleus accumbens (nac) and demonstrated a necessary role for homer2 within the shell subregion in ma reward and reinforcement in mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
to determine whether homer2b within nac subregions played an active role in regulating ma reward and reinforcement, we characterized the ma phenotype of constitutive |
2020-09-28 |
2023-08-13 |
mouse |
| Md Taufiq Nasseef, Jai Puneet Singh, Aliza T Ehrlich, Michael McNicholas, Da Woon Park, Weiya Ma, Praveen Kulkarni, Brigitte L Kieffer, Emmanuel Darc. Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice. ACS pharmacology & translational science. vol 2. issue 4. 2020-09-28. PMID:32259060. |
seed-to-voxel fc analysis (hypothesis-driven) was then focused on pag and nac considered key pain and reward centers. |
2020-09-28 |
2023-08-13 |
mouse |
| Md Taufiq Nasseef, Jai Puneet Singh, Aliza T Ehrlich, Michael McNicholas, Da Woon Park, Weiya Ma, Praveen Kulkarni, Brigitte L Kieffer, Emmanuel Darc. Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice. ACS pharmacology & translational science. vol 2. issue 4. 2020-09-28. PMID:32259060. |
further seed-to-seed quantification showed highest fc modifications of both pag and nac seeds with hypothalamic and amygdalar areas, as well as between them, revealing the strongest impact across reward and aversion/pain centers of the brain. |
2020-09-28 |
2023-08-13 |
mouse |
| Madoka Anan, Ryoko Higa, Kenshiro Shikano, Masahito Shide, Akinobu Soda, Magdeline E Carrasco Apolinario, Kenji Mori, Toshitaka Shin, Mikiya Miyazato, Hiromitsu Mimata, Takatoshi Hikida, Toshikatsu Hanada, Kazuwa Nakao, Kenji Kangawa, Reiko Hanad. Cocaine has some effect on neuromedin U expressing neurons related to the brain reward system. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32462086. |
in this study, we found that some of cocaine-induced c-fos immunoreactive cells were co-localized with nmu in the nucleus accumbens (nac), caudate putamen (cpu), and basolateral amygdala (bla), which are key brain regions associated with the brain reward system, in wild type mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Alessandra Porcu, Megan Vaughan, Anna Nilsson, Natsuko Arimoto, Katja Lamia, David K Wels. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 24. 2020-09-14. PMID:32487727. |
the nucleus accumbens (nac), a central component of the midbrain dopamine reward circuit, exhibits disturbed circadian rhythms in the postmortem brains of depressed patients. |
2020-09-14 |
2023-08-13 |
mouse |
| Alessandra Porcu, Megan Vaughan, Anna Nilsson, Natsuko Arimoto, Katja Lamia, David K Wels. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 24. 2020-09-14. PMID:32487727. |
our data reveal a causal role for cry in regulating the midbrain dopamine reward system, and provide a mechanistic link between the nac circadian clock and vulnerability to depression. |
2020-09-14 |
2023-08-13 |
mouse |
| Alexey Bingor, Tomer Haham, Claire Thornton, Yael Stern-Bach, Rami Yak. Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors. Nature communications. vol 11. issue 1. 2020-09-09. PMID:32703948. |
introducing the cleavable arginine-alanine peptide into the nac attenuated expression of cocaine-conditioned reward. |
2020-09-09 |
2023-08-13 |
Not clear |
| Weichen Song, Yifeng Shen, Yanhua Zhang, Sufang Peng, Ran Zhang, Ailing Ning, Huafang Li, Xia Li, Guan Ning Lin, Shunying Y. Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats. BMC medical informatics and decision making. vol 19. issue Suppl 6. 2020-08-04. PMID:31856805. |
nucleus accumbens (nac) is a vital brain region for the process of reward and stress, whereas microrna plays a crucial role in depression pathology. |
2020-08-04 |
2023-08-13 |
rat |