| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Schroeder, Jay P Nakamura, Matthew Hudson, Nigel C Jones, Xin Du, Suresh Sundram, Rachel A Hil. Raloxifene recovers effects of prenatal immune activation on cognitive task-induced gamma power. Psychoneuroendocrinology. vol 110. 2020-08-03. PMID:31546114. |
local field potentials from the ca1 hippocampus were simultaneously recorded during the y-maze test of short term spatial memory and the cheeseboard maze test of long-term spatial learning and memory and cognitive flexibility. |
2020-08-03 |
2023-08-13 |
mouse |
| Ruiqing Zhou, Jing Zhao, Danyang Li, Yao Chen, Yanyan Xiao, Anni Fan, Xiang-Tao Chen, Hui-Li Wan. Combined exposure of lead and cadmium leads to the aggravated neurotoxicity through regulating the expression of histone deacetylase 2. Chemosphere. vol 252. 2020-06-18. PMID:32234630. |
the results of morris water maze (mwm), y maze and golgi-cox staining showed that either pb or cd alone exposure damaged the ability of learning and memory and decreased the dendritic spine density in both the hippocampal ca1 and dg area of sprague---dawley (sd) rats, and that the co-exposure aggravated the damages. |
2020-06-18 |
2023-08-13 |
rat |
| Narges Karimi, Mahnaz Bayat, Masoud Haghani, Hamed Fahandezh Saadi, Gholam Reza Ghazipou. 2.45 GHz microwave radiation impairs learning, memory, and hippocampal synaptic plasticity in the rat. Toxicology and industrial health. vol 34. issue 12. 2020-06-17. PMID:30345889. |
our results showed that mw radiation exposure decreased the learning and memory performance that was associated with decrement of long-term potentiation induction and excitability of ca1 neurons. |
2020-06-17 |
2023-08-13 |
rat |
| Yuan-Yuan Han, Zhao-Hui Chen, Ying-Jie Shang, Wen-Wen Yan, Bao-Yan Wu, Chu-Hua L. Cordycepin improves behavioral-LTP and dendritic structure in hippocampal CA1 area of rats. Journal of neurochemistry. vol 151. issue 1. 2020-06-16. PMID:31314908. |
these results suggested that cordycepin improved behavioral-ltp and morphological structure of dendrite in hippocampal ca1 but did not contribute to the improvement of learning and memory. |
2020-06-16 |
2023-08-13 |
rat |
| Huan Xiao, Xiao-Jiao Ma, Ou-Mei Cheng, Hong-Mei Qiu, Qing-Song Jian. [Gastrodin improves hippocampal neurogenesis by NO-cGMP-PKG signaling pathway in cerebral ischemic mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 24. 2020-05-05. PMID:32237394. |
treatment with different doses of gastrodin( 50 and 100 mg·kg-1) significantly ameliorated the pathological damages in the ca1 region,improved the ability of learning and memory,and promoted hippocampal neurogenesis. |
2020-05-05 |
2023-08-13 |
mouse |
| Qian Su, Huiping Zhang, Shaokang Dang, Dan Yao, Shuya Shao, Zhongliang Zhu, Hui L. Hippocampal Protein Kinase C Gamma Signaling Mediates the Impairment of Spatial Learning and Memory in Prenatally Stressed Offspring Rats. Neuroscience. vol 414. 2020-03-13. PMID:31283971. |
overexpression of pkcγ in the hippocampal ca1 area recovered the ability of spatial learning and memory in ps female offspring. |
2020-03-13 |
2023-08-13 |
rat |
| Yue Hei, Rong Chen, Xingang Mao, Jiancai Wang, Qianfa Long, Weiping Li. Neuregulin1 attenuates cognitive deficits and hippocampal CA1 neuronal apoptosis partly via ErbB4 receptor in a rat model of chronic cerebral hypoperfusion. Behavioural brain research. vol 365. 2020-03-09. PMID:30826297. |
the results showed that nrg1 significantly improved the performances in mwm (spatial learning and memory) and rawm (spatial working and reference memory), attenuated hippocampal ca1 neuronal loss and apoptosis, upregulated the expression of perbb4/erbb4 and the anti-apoptotic protein bcl-2, and downregulated the expression of pro-apoptotic proteins of cleaved (cl)-caspase3 and bax. |
2020-03-09 |
2023-08-13 |
rat |
| Nadia Yanet Cortés-Álvarez, César Rubén Vuelvas-Olmos, María Fernanda Pinto-González, Jorge Guzmán-Muñiz, Oscar Gonzalez-Perez, Norma Angélica Moy-Lópe. A high-fat diet during pregnancy impairs memory acquisition and increases leptin receptor expression in the hippocampus of rat offspring. Nutritional neuroscience. 2020-02-20. PMID:32075550. |
this study examined the effect of maternal hfd during gestation on ob-r expression in the ca1 and ca3 hippocampal regions, and its relationship with spatial learning and memory in the offspring. |
2020-02-20 |
2023-08-13 |
rat |
| Yanjun Sun, Suoqin Jin, Xiaoxiao Lin, Lujia Chen, Xin Qiao, Li Jiang, Pengcheng Zhou, Kevin G Johnston, Peyman Golshani, Qing Nie, Todd C Holmes, Douglas A Nitz, Xiangmin X. CA1-projecting subiculum neurons facilitate object-place learning. Nature neuroscience. vol 22. issue 11. 2020-01-31. PMID:31548723. |
we identify a critical role for ca1-projecting subicular neurons in object-location learning and memory, and show that this projection modulates place-specific activity of ca1 neurons and their responses to displaced objects. |
2020-01-31 |
2023-08-13 |
Not clear |
| Praveen K Kodumuri, Christofer Thomas, Raghu Jetti, Anil Kumar Pande. Fenugreek seed extract ameliorates cognitive deficits in streptozotocin-induced diabetic rats. Journal of basic and clinical physiology and pharmacology. vol 30. issue 4. 2020-01-06. PMID:31326961. |
learning and memory impairment in diabetic animals is associated with increased blood glucose levels, increased oxidative stress in the hippocampus and decreased number of neurons in the ca1 and ca3 regions of the hippocampus. |
2020-01-06 |
2023-08-13 |
rat |
| Jue Liu, Yangyang Huang, Fei Cai, Yao Dang, Chunsheng Liu, Jianghua Wan. MicroRNA-181a regulates endoplasmic reticulum stress in offspring of mice following prenatal microcystin-LR exposure. Chemosphere. vol 240. 2020-01-03. PMID:31563103. |
our results showed that mclr prenatal exposure led to the impairment of learning and memory function in offspring on postnatal days (pnd) 35, accompanied by endoplasmic reticulum (er) stress and neuronal apoptosis in hippocampal ca1 regions of mice. |
2020-01-03 |
2023-08-13 |
mouse |
| Mengying Liu, Fangzhou Xing, Chen Bian, Yangang Zhao, Jikai Zhao, Yan Liu, Jiqiang Zhan. Letrozole induces worse hippocampal synaptic and dendritic changes and spatial memory impairment than ovariectomy in adult female mice. Neuroscience letters. vol 706. 2019-12-27. PMID:31077740. |
changes in the ca1 spine density, synapse density and spatial learning and memory after ovx and let were also investigated. |
2019-12-27 |
2023-08-13 |
mouse |
| Yuan Ge, Meng Tian, Lidong Liu, Tak Pan Wong, Bo Gong, Dongchuan Wu, Taesup Cho, Shujun Lin, Jürgen Kast, Jie Lu, Yu Tian Wan. p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression. Nature communications. vol 10. issue 1. 2019-12-18. PMID:31501443. |
in particular, the rapid insertion of the glua1 homomeric (glua1-homo) ampars into the postsynaptic membrane is considered to be critical in the expression of hippocampal ca1 long-term potentiation (ltp), which is important for certain forms of learning and memory. |
2019-12-18 |
2023-08-13 |
Not clear |
| A L Uhernik, Z T Montoya, C D Balkissoon, J P Smit. Learning and memory is modulated by cannabidiol when administered during trace fear-conditioning. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29432803. |
because synaptic plasticity is the fundamental mechanism of learning and memory, we also evaluated the impact of cbd on trace conditioning-dependent dendritic spine plasticity which occurred in the dorsal lateral amygdala and ca1 region of the ventral hippocampus. |
2019-09-16 |
2023-08-13 |
mouse |
| Samer Siwani, Arthur S C França, Sanja Mikulovic, Amilcar Reis, Markus M Hilscher, Steven J Edwards, Richardson N Leão, Adriano B L Tort, Klas Kullande. OLMα2 Cells Bidirectionally Modulate Learning. Neuron. vol 99. issue 2. 2019-08-01. PMID:29983324. |
here we set out to determine whether selective modulation of olmα2 cells in the intermediate ca1 affects learning and memory in vivo. |
2019-08-01 |
2023-08-13 |
mouse |
| Samer Siwani, Arthur S C França, Sanja Mikulovic, Amilcar Reis, Markus M Hilscher, Steven J Edwards, Richardson N Leão, Adriano B L Tort, Klas Kullande. OLMα2 Cells Bidirectionally Modulate Learning. Neuron. vol 99. issue 2. 2019-08-01. PMID:29983324. |
these results suggest that intermediate olmα2 cells are an important component in the ca1 microcircuit regulating learning and memory processes. |
2019-08-01 |
2023-08-13 |
mouse |
| Xiankun Zhu, Pei Wang, Haijun Liu, Jing Zhan, Jin Wang, Mi Li, Ling Zeng, Ping X. Changes and Significance of SYP and GAP-43 Expression in the Hippocampus of CIH Rats. International journal of medical sciences. vol 16. issue 3. 2019-07-24. PMID:30911273. |
in this study, 25 adult male sprague dawley (sd) rats were randomly divided into a normal control group (con) and a chronic intermittent hypoxia group (cih) with four time points as follows: 1 w, 2 w, 3 w, and 4 w. the behavioural changes (primarily learning and memory abilities) were observed by the morris water maze in each group, consisting of 5 rats per group.the localization of syp and gap-43 in hippocampal ca1 neurons was observed, and the expression of syp and gap-43 in the hippocampus was detected by western blotting. |
2019-07-24 |
2023-08-13 |
rat |
| P C Bello-Medina, R A Prado-Alcalá, S Rivas-Arancibi. Effect of Ozone Exposure on Dendritic Spines of CA1 Pyramidal Neurons of the Dorsal Hippocampus and on Object-place Recognition Memory in Rats. Neuroscience. vol 402. 2019-06-21. PMID:30685541. |
the purpose of this research was to evaluate whether chronic exposure to ozone produces a deleterious effect on density and morphology of dendritic spines in ca1 of dorsal hippocampus and on learning and memory of object-place recognition. |
2019-06-21 |
2023-08-13 |
rat |
| Ying Liu, An Qi Li, Wan Ma, Yu Bo Gao, Li Qin Deng, Chun Zhang, Jin Hai Men. Limb Remote Ischemic Preconditioning Reduces Repeated Ketamine Exposure-Induced Adverse Effects in the Developing Brain of Rats. Journal of molecular neuroscience : MN. vol 68. issue 1. 2019-05-29. PMID:30847723. |
the results showed increased cleaved caspase-3 protein levels in the cerebral cortex and the hippocampal ca1 region, severe cell damage and dna breakage, and decreased spatial learning and memory abilities in the ketamine group in comparison with controls. |
2019-05-29 |
2023-08-13 |
rat |
| Lei Li, Rongli Yang, Pingjing Li, Hailong Lu, Jingbo Hao, Liyan Li, Donovan Tucker, Quanguang Zhan. Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28271403. |
we report that both the neuronal survival in the hippocampal ca1 region and the hippocampus-dependent spatial learning and memory in the combined treatment animals were enhanced compared to those in the single treatment animals. |
2019-05-23 |
2023-08-13 |
Not clear |