| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
the results indicate that hsya may enhance the endogenous expression of bdnf and glun2b, which are associated with the synaptic plasticity of the hippocampus, and may improve spatial learning and memory abilities in a rat model of vad. |
2017-06-28 |
2023-08-13 |
rat |
| Sorabh Sharma, Rajeev Taliya. Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. Neuropharmacology. vol 105. 2017-06-22. PMID:26805421. |
these mice also showed a severe deficit in learning and memory along with reduced histone h3 acetylation and bdnf levels. |
2017-06-22 |
2023-08-13 |
mouse |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
it was concluded that the "nourishing liver and kidney" acupuncture therapy has positive effects on behavioral recovery, as well as learning and memory abilities, probably by promoting the expression of bdnf and syn, and synaptic structure reconstruction in the ipsilateral hippocampus after i/r in rats. |
2017-06-13 |
2023-08-13 |
rat |
| Mahmoud A Alomari, Omar F Khabour, Karem H Alzoubi, Mohammad A Alzub. Combining restricted diet with forced or voluntary exercises improves hippocampal BDNF and cognitive function in rats. The International journal of neuroscience. vol 126. issue 4. 2017-05-03. PMID:26000806. |
hippocampal bdnf was measured using elisa while learning and memory formation were assessed with the radial arm water maze (rawm) paradigm. |
2017-05-03 |
2023-08-13 |
rat |
| Mahmoud A Alomari, Omar F Khabour, Karem H Alzoubi, Mohammad A Alzub. Combining restricted diet with forced or voluntary exercises improves hippocampal BDNF and cognitive function in rats. The International journal of neuroscience. vol 126. issue 4. 2017-05-03. PMID:26000806. |
additionally, rdt alone neither modulated bdnf level nor enhanced learning and memory formation (p > 0.05). |
2017-05-03 |
2023-08-13 |
rat |
| Xiaoqian Luan, Jingyan Tao, Jie Zhang, Ying Xie, Xiangyang Zhang, Hang Su, Jincai H. Increased BDNF may not be associated with cognitive impairment in heroin-dependent patients. Medicine. vol 96. issue 15. 2017-04-28. PMID:28403087. |
a growing number of evidence suggests that brain-derived neurotrophic factor (bdnf) plays an important part in modulating the activities on the basis of hippocampus neural plasticity, such as learning and memory. |
2017-04-28 |
2023-08-13 |
human |
| Nesli Avgan, Heidi G Sutherland, Lauren K Spriggens, Chieh Yu, Omar Ibrahim, Claire Bellis, Larisa M Haupt, David H K Shum, Lyn R Griffith. BDNF Variants May Modulate Long-Term Visual Memory Performance in a Healthy Cohort. International journal of molecular sciences. vol 18. issue 3. 2017-04-21. PMID:28304362. |
brain-derived neurotrophic factor (bdnf) is involved in numerous cognitive functions including learning and memory. |
2017-04-21 |
2023-08-13 |
rat |
| Su-Zhen Guan, Li Ning, Ning Tao, Yu-Long Lian, Ji-Wen Liu, Tzi Bun N. Effects of maternal stress during pregnancy on learning and memory via hippocampal BDNF, Arc (Arg3.1) expression in offspring. Environmental toxicology and pharmacology. vol 46. 2017-02-08. PMID:27474832. |
effects of maternal stress during pregnancy on learning and memory via hippocampal bdnf, arc (arg3.1) expression in offspring. |
2017-02-08 |
2023-08-13 |
rat |
| Su-Zhen Guan, Li Ning, Ning Tao, Yu-Long Lian, Ji-Wen Liu, Tzi Bun N. Effects of maternal stress during pregnancy on learning and memory via hippocampal BDNF, Arc (Arg3.1) expression in offspring. Environmental toxicology and pharmacology. vol 46. 2017-02-08. PMID:27474832. |
the intrauterine environment has a significant long-term impact on individual's life, this study was designed to investigate the effect of stress during pregnancy on offspring's learning and memory abilities and analyze its mechanisms from the expression of bdnf and arc in the hippocampus of the offspring. |
2017-02-08 |
2023-08-13 |
rat |
| Su-Zhen Guan, Li Ning, Ning Tao, Yu-Long Lian, Ji-Wen Liu, Tzi Bun N. Effects of maternal stress during pregnancy on learning and memory via hippocampal BDNF, Arc (Arg3.1) expression in offspring. Environmental toxicology and pharmacology. vol 46. 2017-02-08. PMID:27474832. |
collectively, these findings disclose that long-time maternal stress during pregnancy could destroy spatial learning and memory abilities of the offspring, the mechanism of which is related to been improving maternal plasma corticosterone and reduced hippocampal bdnf, arc of offspring rats. |
2017-02-08 |
2023-08-13 |
rat |
| Judit Zsuga, Gabor Tajti, Csaba Papp, Bela Juhasz, Rudolf Gesztely. FNDC5/irisin, a molecular target for boosting reward-related learning and motivation. Medical hypotheses. vol 90. 2017-01-06. PMID:27063080. |
bdnf is a neurotropic factor that increases neuronal dopamine content, modulates dopamine release relevant for neuronal plasticity and increased neuronal survival as well as learning and memory. |
2017-01-06 |
2023-08-13 |
Not clear |
| Kay L H Wu, Chih-Wei Wu, You-Lin Tain, Li-Tung Huang, Yung-Mei Chao, Chun-Ying Hung, Jin-Cheng Wu, Siang-Ru Chen, Pei-Chia Tsai, Julie Y H Cha. Environmental stimulation rescues maternal high fructose intake-impaired learning and memory in female offspring: Its correlation with redistribution of histone deacetylase 4. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26872592. |
together these results suggest that later life environmental stimulation effectively rescues the impairment of hippocampal learning and memory in female offspring to maternal hfd intake through redistributing nuclear hdac4 to increase bdnf expression. |
2016-12-30 |
2023-08-13 |
rat |
| Bo Jiang, Lu Song, Chao Huang, Wei Zhan. P7C3 Attenuates the Scopolamine-Induced Memory Impairments in C57BL/6J Mice. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26646000. |
therefore, these findings suggest that p7c3 could improve the scopolamine-induced learning and memory impairment possibly through activation of bdnf signaling pathway, thereby exhibiting a cognition-enhancing potential. |
2016-12-13 |
2023-08-13 |
mouse |
| Zheng Cao, Xu Yang, Haiyang Zhang, Haoran Wang, Wanyue Huang, Feibo Xu, Cuicui Zhuang, Xiaoguang Wang, Yanfei L. Aluminum chloride induces neuroinflammation, loss of neuronal dendritic spine and cognition impairment in developing rat. Chemosphere. vol 151. 2016-11-03. PMID:26946116. |
these results showed exposure to alcl3 lead to increased mrna levels of il-1β, il-6, tnf-α and mch ii, decreased mrna levels of cx3cl1 and bdnf, decreased density of dendritic spine and impaired learning and memory in developing rat. |
2016-11-03 |
2023-08-13 |
rat |
| N Zhang, M Xing, Y Wang, H Tao, Y Chen. Repetitive transcranial magnetic stimulation enhances spatial learning and synaptic plasticity via the VEGF and BDNF-NMDAR pathways in a rat model of vascular dementia. Neuroscience. vol 311. 2016-09-14. PMID:26518460. |
these results suggest that rtms improved learning and memory in the vad model rats via the up-regulation of vegf, bdnf and nmdars. |
2016-09-14 |
2023-08-13 |
rat |
| Yun-yue Ju, Jian-dong Long, Yao Liu, Jing-gen Li. Formation of aversive memories associated with conditioned drug withdrawal requires BDNF expression in the amygdala in acute morphine-dependent rats. Acta pharmacologica Sinica. vol 36. issue 12. 2016-08-18. PMID:26567727. |
brain-derived neurotrophic factor (bdnf) plays an important role in learning and memory in multiple brain areas. |
2016-08-18 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Ning Li, Yue Zhang, Guo-Liang Qiu, Cheng-Hao Chu, Cai-Yun Wang, Gan Qin, Fei-Hu Che. Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. Endocrine journal. vol 62. issue 10. 2016-08-17. PMID:26228795. |
these findings indicated an amelioration effect of res on the spatial learning and memory in the sch rats, the mechanism of which might be involved with its ability of modifying the hyperactive hpt axis and up-regulating the hippocampal hypo-expression of syt-1 and bdnf. |
2016-08-17 |
2023-08-13 |
rat |
| Reihane Seifi Moroudi, Ali Akbar Masoudi, Rasoul Vaez Torshizi, Mohammad Zand. Identification of learning and memory genes in canine; promoter investigation and determining the selective pressure. Molecular biology reports. vol 41. issue 12. 2016-06-07. PMID:25192892. |
the results showed that bdnf, tac1 and cck genes are expressed in the dog hippocampus, therefore, these genes could be strong candidates associated with learning and memory in dogs. |
2016-06-07 |
2023-08-13 |
mouse |
| J Li, X Ding, R Zhang, W Jiang, X Sun, Z Xia, X Wang, E Wu, Y Zhang, Y H. Harpagoside ameliorates the amyloid-β-induced cognitive impairment in rats via up-regulating BDNF expression and MAPK/PI3K pathways. Neuroscience. vol 303. 2016-05-06. PMID:26135675. |
taken together, har exerting neuroprotection effect and ameliorating learning and memory deficit appears to be associated, at least in part, with up-regulation of bdnf content as well as activating its downstream signaling pathways, e.g., mapk/pi3k pathways. |
2016-05-06 |
2023-08-13 |
rat |
| Heather Bowling, Aditi Bhattacharya, Eric Klann, Moses V Cha. Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural regeneration research. vol 11. issue 3. 2016-04-29. PMID:27127458. |
brain-derived neurotrophic factor (bdnf) plays an important role in neurodevelopment, synaptic plasticity, learning and memory, and in preventing neurodegeneration. |
2016-04-29 |
2023-08-13 |
Not clear |