| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuanyu Song, Yinghua Chen, Wei Sun, Changqing Li, Junfeng Li, Haoyu Wang, Ruiqi Qin, Xiaoqing Su, Tong Wu, Hongxu Zhao, Yusheng Ha. [Exploration of electroacupuncture at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) for attenuating learning and memory impairment in vascular dementia rats based on NMDAR/CREB/BDNF signaling pathway]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 44. issue 12. 2024-12-10. PMID:39658379. |
to explore the mechanism of electroacupuncture (ea) at "fengchi" (gb 20) and "sishencong" (ex-hn 1) on learning and memory impairment in vascular dementia (vd) rats by observing the influences on the n-methyl-d-aspartate receptor (nmdar)/cyclic adenosine monophosphate response element-binding protein (creb)/brain-derived neurotrophic factor (bdnf) signaling pathway and the excitotoxicity induced by hippocampal calcium overload. |
2024-12-10 |
2024-12-13 |
rat |
| Mousa Shaabani Ghahremanlo, Vida Hojati, Gholamhassan Vaezi, Shahram Sharaf. Transgenerational of Oxidative Damage Induced by Prenatal Ethanol Exposure on Spatial Learning/Memory and BDNF in the of Male Rats. IBRO neuroscience reports. vol 17. 2024-11-25. PMID:39583589. |
this study investigates how prenatal ethanol exposure triggers oxidative stress (os) and affects neurotrophic factors (ntfs), particularly brain-derived growth factor (bdnf) gene expression in the hippocampus, influencing learning and memory decline across two generations of male offspring from ethanol-exposed female rats. |
2024-11-25 |
2024-11-27 |
rat |
| Lilian Leite Fausto, Adriano Alberti, Gabriela Kades, Risoní Pereira Dias de Carvalho, Viviane Freiberger, Leticia Ventura, Paula Dias, Eliton Marcio Zanoni, Ben Hur Soares, Matheus Luchini Dutra, Daniel Fernandes Martins, Clarissa Martinelli Comi. Effects of a Ketogenic Diet on the Assessment of Biochemical and Clinical Parameters in Duchenne Muscular Dystrophy: A Preclinical Investigation. Molecular neurobiology. vol 61. issue 12. 2024-11-22. PMID:38816675. |
overall, a 14-day dcet showed protective effects by improving spatial learning and memory through reductions in oxidative stress and immune response, as well as increases in bdnf levels, consistent with our study's findings. |
2024-11-22 |
2024-11-24 |
mouse |
| Taotao Zhao, Jia Lv, Mingyuan Peng, Jiahui Mi, Shaosan Zhang, Jie Liu, Tong Chen, Zilong Sun, Ruiyan Ni. Fecal microbiota transplantation and short-chain fatty acids improve learning and memory in fluorosis mice by BDNF-PI3K/AKT pathway. Chemico-biological interactions. 2024-11-04. PMID:39491142. |
of note, scfas administration also increased bdnf levels and regulated its downstream pathways, which contributed to cell survival and learning and memory function recovery. |
2024-11-04 |
2024-11-06 |
mouse |
| Bao-Wen Zhang, Ying Li, Xian-Juan Ko. [Resistance exercise regulates hippocampal microglia polarization through TREM2/NF-κB/STAT3 signal pathway to improve cognitive dysfunction in T2DM mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468808. |
the results showed that the spatial learning and memory of the db/db group were significantly declined, the neurons in the hippocampus were damaged, the protein levels of psd93, psd95, bdnf, cd206, arg1, trem2 and the ratio of p-creb/creb were significantly down-regulated, the mrna and protein expression levels of il-6, il-1β and tnf-α were significantly up-regulated, and the protein levels of inos, iba-1, nf-κb and the ratio of p-stat3/stat3 were significantly increased compared with the con group. |
2024-10-29 |
2024-10-31 |
mouse |
| Mamoru Fukuchi, Yumi Shibasaki, Yuto Akazawa, Hitoshi Suzuki-Masuyama, Ken-Ichi Takeuchi, Yumika Iwazaki, Akiko Tabuchi, Masaaki Tsud. Neuron-selective and activity-dependent splicing of BDNF exon I-IX pre-mRNA. Neurochemistry international. 2024-10-25. PMID:39455010. |
brain-derived neurotrophic factor (bdnf) is essential for numerous neuronal functions, including learning and memory. |
2024-10-25 |
2024-10-29 |
mouse |
| Shunsuke Shimizu, Aoi Nakano, Daisuke Ihara, Hironori Nakayama, Michiko Jo, Kazufumi Toume, Katsuko Komatsu, Naotoshi Shibahara, Masaaki Tsuda, Mamoru Fukuchi, Akiko Tabuch. Panax notoginseng root extract induces nuclear translocation of CRTC1 and Bdnf mRNA expression in cortical neurons. Drug discoveries & therapeutics. 2024-10-23. PMID:39443121. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family, is deeply involved in the development and higher function of the nervous system, including learning and memory. |
2024-10-23 |
2024-10-26 |
mouse |
| Mark H Tuszynsk. Growth Factor Gene Therapy for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 101. issue s1. 2024-10-18. PMID:39422960. |
in animal models of alzheimer's disease (ad), the growth factor brain derived neurotrophic factor (bdnf) prevents neuronal death, activates neuronal function, builds new synapses and improves learning and memory. |
2024-10-18 |
2024-10-20 |
Not clear |
| Fidanka Vasileva, Raquel Font-Lladó, Gemma Carreras-Badosa, Víctor López-Ros, Anna Ferrusola-Pastrana, Abel López-Bermejo, Anna Prats-Pui. Increased Salivary BDNF and Improved Fundamental Motor Skills in Children Following a 3-Month Integrated Neuromuscular Training in Primary School. Journal of functional morphology and kinesiology. vol 9. issue 3. 2024-09-23. PMID:39311262. |
brain-derived neurotrophic factor (bdnf) is a protein involved in synaptic transmission and neuronal plasticity, which underlie the processes of learning and memory formation. |
2024-09-23 |
2024-09-26 |
Not clear |
| Tuğba Sezer, Nilsel Okudan, Muaz Belviranl. Comparing the effect of high-intensity interval exercise and voluntary exercise training on cognitive functions in rats. Neuroscience letters. 2024-09-21. PMID:39306028. |
it is known that exercise increases brain-derived neurotrophic factor (bdnf) levels in the hippocampus, the brain region responsible for learning and memory, resulting in improved cognitive functions and learning processes. |
2024-09-21 |
2024-09-24 |
human |
| Robert S Gardner, Matthew T Ambalavanar, Paul E Gold, Donna L Koro. Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211174. |
enhancement of learning and memory by cognitive and physical exercise may be mediated by brain-derived neurotrophic factor (bdnf) acting at tropomyosin receptor kinase b (trkb). |
2024-08-30 |
2024-09-04 |
rat |
| Robert S Gardner, Matthew T Ambalavanar, Paul E Gold, Donna L Koro. Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211174. |
most prior studies of bdnf and 7,8-dhf effects on learning and memory have administered the drugs for days to months before assessing effects on cognition. |
2024-08-30 |
2024-09-04 |
rat |
| Robert S Gardner, Matthew T Ambalavanar, Paul E Gold, Donna L Koro. Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211174. |
the findings that a single, intra-striatal infusion of 7,8-dhf 20 min before training enhanced response learning in rats suggest that, in addition to its trophic effects, bdnf modulates learning and memory through receptor mediated cell signaling events. |
2024-08-30 |
2024-09-04 |
rat |
| Lorenzo Morè, Lucia Privitera, Marcia Lopes, J Simon C Arthur, Julie C Lauterborn, Sonia A L Corrêa, Bruno G Frenguell. MSK1 is required for the experience- and ampakine-dependent enhancement of spatial reference memory and reversal learning. Neuropharmacology. 2024-08-11. PMID:39128584. |
we have previously shown that msk1, by virtue of its ability to regulate gene transcription, converts the elevation of bdnf associated with environmental enrichment into molecular, synaptic, cognitive and genomic adaptations that underlie enrichment-induced enhanced synaptic plasticity and learning and memory, a property that msk1 retains across the lifespan. |
2024-08-11 |
2024-08-14 |
mouse |
| Farhad Sanaeifar, Sina Pourranjbar, Mohammad Pourranjbar, Sana Ramezani, Samira Rostami Mehr, Al-Hassan Soliman Wadan, Farnaz Khazeifar. Beneficial effects of physical exercise on cognitive-behavioral impairments and brain-derived neurotrophic factor alteration in the limbic system induced by neurodegeneration. Experimental gerontology. 2024-08-08. PMID:39116955. |
neurotrophins such as brain-derived neurotrophic factor (bdnf) are critical for neuron survival and synaptic plasticity, which is required for learning and memory. |
2024-08-08 |
2024-08-12 |
Not clear |
| Amir Basiri, Saeid Izadi, Samaneh Kakhki, Vida Alikahni, Saeedeh Askarian, Farimah Behesht. N‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response and BDNF in hippocampal tissues. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087834. |
n‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response and bdnf in hippocampal tissues. |
2024-08-01 |
2024-08-03 |
rat |
| Ali Niapour, Maryam Abdollahzadeh, Safa Ghaheri Fard, Hakimeh Saadat. The therapeutic potential of 1, 25-dihydroxy vitamin D3 on cisplatin-affected neurological functions is associated with the regulation of oxidative stress and inflammatory markers as well as levels of MMP2/9. Metabolic brain disease. 2024-07-17. PMID:39017968. |
the neuroprotective influence of calcitriol supplementation (100ng/kg/day for 5 weeks) was assessed through behavioral, electrophysiological, and molecular experiments. cisplatin administration impaired spatial learning and memory and decreased prefrontal brain-derived neurotrophic factor (bdnf). |
2024-07-17 |
2024-07-19 |
rat |
| Ali Niapour, Maryam Abdollahzadeh, Safa Ghaheri Fard, Hakimeh Saadat. The therapeutic potential of 1, 25-dihydroxy vitamin D3 on cisplatin-affected neurological functions is associated with the regulation of oxidative stress and inflammatory markers as well as levels of MMP2/9. Metabolic brain disease. 2024-07-17. PMID:39017968. |
learning and memory impairments along with bdnf changes caused by cisplatin were amended with calcitriol supplementation. |
2024-07-17 |
2024-07-19 |
rat |
| Forough Radfar, Mehdi Shahbazi, Shahzad Tahmasebi Boroujeni, Elahe Arab Ameri, Maryam Farahmandfa. Moderate aerobic training enhances the effectiveness of insulin therapy through hypothalamic IGF1 signaling in rat model of Alzheimer's disease. Scientific reports. vol 14. issue 1. 2024-07-10. PMID:38987609. |
we investigated the effects of treadmill exercise and intranasal insulin on learning and memory impairment and the expression of igf1, bdnf, and glut4 in hypothalamus. |
2024-07-10 |
2024-07-13 |
rat |
| Kuang-Min Cheng, Wei-Lun Hsu, Yun-Li Ma, Yen-Chen Liu, Eminy H Y Le. Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-06-20. PMID:38900294. |
whereas knockdown of bdnf, integrin α3 or sgk1 expression impairs spatial learning and memory, it does not affect y-maze performance, suggesting that bdnf, integrin α3 and sgk1 are involved in long-term memory formation, but not short-term memory formation. |
2024-06-20 |
2024-06-22 |
mouse |