| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
the objective of the present study was to investigate the effects of lacosamide (lcm) on learning and memory processes in rats, on the serum level of brain-derived neurotrophic factor (bdnf) and bdnf/trkb ligand receptor system expression in the hippocampal formation. |
2019-03-15 |
2023-08-13 |
rat |
| Junfei Zhou, Fang Wang, Jun Zhang, Jianfeng Li, Li Ma, Tieli Dong, Zhigang Zhuan. The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction : Mechanism for the effects of propofol on cognitive function. BMC anesthesiology. vol 18. issue 1. 2019-03-08. PMID:29621970. |
the aim of the present study was to verify whether propofol impaired learning and memory through the interplay of n-methyl-d-aspartate (nmda) receptor with brain-derived neurotrophic factor (bdnf)-tyrosine kinase b (trkb) signaling pathway. |
2019-03-08 |
2023-08-13 |
Not clear |
| Julien Gibon, Philip A Barke. Neurotrophins and Proneurotrophins: Focus on Synaptic Activity and Plasticity in the Brain. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 23. issue 6. 2019-03-04. PMID:28303740. |
in the present review, we explore the role of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt3), and neurotrophin 4 (nt4) and their respective proform in cellular processes related to learning and memory. |
2019-03-04 |
2023-08-13 |
Not clear |
| Yousef Baghcheghi, Farimah Beheshti, Mohammad Naser Shafei, Hossein Salmani, Hamid Reza Sadeghnia, Mohammad Soukhtanloo, Akbar Anaeigoudari, Mahmoud Hossein. The effects of vitamin E on brain derived neurotrophic factor, tissues oxidative damage and learning and memory of juvenile hypothyroid rats. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29290043. |
the effects of vitamin e (vit e) on brain derived neurotrophic factor (bdnf) and brain tissues oxidative damage as well as on learning and memory impairments in juvenile hypothyroid rats were examined. |
2019-02-05 |
2023-08-13 |
rat |
| Yousef Baghcheghi, Farimah Beheshti, Mohammad Naser Shafei, Hossein Salmani, Hamid Reza Sadeghnia, Mohammad Soukhtanloo, Akbar Anaeigoudari, Mahmoud Hossein. The effects of vitamin E on brain derived neurotrophic factor, tissues oxidative damage and learning and memory of juvenile hypothyroid rats. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29290043. |
the results of the present study showed that vit e improved bdnf and prevented from brain tissues oxidative damage as well as learning and memory impairments in juvenile hypothyroid rats. |
2019-02-05 |
2023-08-13 |
rat |
| Asghar Talebian, Kim Robinson-Brookes, Susan O Meaki. TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1. Journal of molecular neuroscience : MN. vol 67. issue 1. 2019-01-31. PMID:30547417. |
while it is known that both bdnf and trkb modulate cellular processes involved in learning and memory, exactly how trkb cross-talks and modulates signaling downstream of excitatory ionotropic receptors, such as the nmda receptor (nmdar), are not well understood. |
2019-01-31 |
2023-08-13 |
Not clear |
| Mohammad Azimi, Reza Gharakhanlou, Nasser Naghdi, Davar Khodadadi, Soomaayeh Heysieattala. Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway. Peptides. vol 102. 2019-01-18. PMID:29309801. |
previous evidence suggested that exercise ameliorates learning and memory deficits by increasing brain derived neurotrophic factor (bdnf) and activating downstream pathways in ad animal models. |
2019-01-18 |
2023-08-13 |
Not clear |
| Mohammad Azimi, Reza Gharakhanlou, Nasser Naghdi, Davar Khodadadi, Soomaayeh Heysieattala. Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway. Peptides. vol 102. 2019-01-18. PMID:29309801. |
we investigated the effects of moderate treadmill exercise on aβ-induced learning and memory impairment as well as the upstream pathway responsible for increasing hippocampal bdnf in an animal model of ad. |
2019-01-18 |
2023-08-13 |
Not clear |
| Simin Afshar, Siamak Shahidi, Ali Haeri Rohani, Alireza Komaki, Sara Soleimani As. The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats. Psychopharmacology. vol 235. issue 10. 2018-12-31. PMID:30027497. |
the effect of nad-299 and tcb-2 on learning and memory, hippocampal bdnf levels and amyloid plaques in streptozotocin-induced memory deficits in male rats. |
2018-12-31 |
2023-08-13 |
rat |
| J-L Rault, A J Lawrence, C R Ralp. Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs. Domestic animal endocrinology. vol 65. 2018-12-27. PMID:30007130. |
higher bdnf concentration is ultimately linked to higher stress resilience, and bdnf in the hippocampus enhances learning and memory. |
2018-12-27 |
2023-08-13 |
Not clear |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
the neurotrophins, especially bdnf, are involved in processes related to learning and memory. |
2018-12-11 |
2023-08-13 |
Not clear |
| Lijuan Man, Xiaoli Lv, Xiang-Dong Du, Guangzhong Yin, Xiaomin Zhu, Yingyang Zhang, Jair C Soares, Xu-Na Yang, Xingshi Chen, Xiang Yang Zhan. Cognitive impairments and low BDNF serum levels in first-episode drug-naive patients with schizophrenia. Psychiatry research. vol 263. 2018-12-11. PMID:29482040. |
evidence shows that bdnf may regulate activity-dependent forms of synaptic plasticity underlying learning and memory. |
2018-12-11 |
2023-08-13 |
Not clear |
| Tae-Woon Kim, Hye-Sang Par. Physical exercise improves cognitive function by enhancing hippocampal neurogenesis and inhibiting apoptosis in male offspring born to obese mother. Behavioural brain research. vol 347. 2018-11-13. PMID:29551732. |
the result showed that deficits in spatial learning and memory, and short-term memory in male offspring born to obese mothers was associated with decreases in brain-derived neurotrophic factor (bdnf) levels and neurogenesis, and an increase in apoptosis in the hippocampal dentate gyrus. |
2018-11-13 |
2023-08-13 |
rat |
| Tae-Woon Kim, Hye-Sang Par. Physical exercise improves cognitive function by enhancing hippocampal neurogenesis and inhibiting apoptosis in male offspring born to obese mother. Behavioural brain research. vol 347. 2018-11-13. PMID:29551732. |
physical exercise improved spatial learning and memory, and short-term memory by enhancing bdnf levels and neurogenesis, and by inhibiting apoptosis in the hippocampal dentate gyrus of male offspring born to obese mothers. |
2018-11-13 |
2023-08-13 |
rat |
| Xiuli Zhang, Xiuhua Wang, Jing Zhang, Xiaohong Pan, Jing Jiang, Yachen L. Effects of Taurine on Alterations of Neurobehavior and Neurodevelopment Key Proteins Expression in Infant Rats by Exposure to Hexabromocyclododecane. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849449. |
these result suggested that higher doses of hbcds early exposure in the developing rats could decrease neurotrophic factors including bdnf, ngf, fgf, which have an impact on neural development, damage on learning and memory. |
2018-10-02 |
2023-08-13 |
rat |
| Mei Cheng, Jiyan Cong, Yulong Wu, Jiacun Xie, Siyuan Wang, Yue Zhao, Xiaoying Zan. Chronic Swimming Exercise Ameliorates Low-Soybean-Oil Diet-Induced Spatial Memory Impairment by Enhancing BDNF-Mediated Synaptic Potentiation in Developing Spontaneously Hypertensive Rats. Neurochemical research. vol 43. issue 5. 2018-09-27. PMID:29574667. |
these findings suggest that chronic swimming exercise can ameliorate the low-soybean-oil diet-induced learning and memory impairment in developing shr through the up-regulation of bdnf and nmdar expression. |
2018-09-27 |
2023-08-13 |
rat |
| Saidan Ding, Zhu Xu, Jianjing Yang, Leping Liu, Xueli Huang, Xuebao Wang, Qichuan Zhug. The Involvement of the Decrease of Astrocytic Wnt5a in the Cognitive Decline in Minimal Hepatic Encephalopathy. Molecular neurobiology. vol 54. issue 10. 2018-07-27. PMID:27878554. |
the decrease of spatial learning and memory and downregulation of astrocytic bdnf and nt-3 were reversed by wnt5a in mhe rat model. |
2018-07-27 |
2023-08-13 |
rat |
| Y-C Guo, X-K Song, Y-F Xu, J-B Ma, J-J Zhang, P-J Ha. The expression and mechanism of BDNF and NGB in perihematomal tissue in rats with intracerebral hemorrhage. European review for medical and pharmacological sciences. vol 21. issue 15. 2018-07-09. PMID:28829495. |
to analyze how changes in the levels of brain-derived neurotrophic factor (bdnf) and neuroglobin (ngb) affect learning and memory in rats with intracerebral hemorrhage. |
2018-07-09 |
2023-08-13 |
rat |
| Yujing Huang, Zhaohui Li, Guangxian Na. Effect of hippocampal L‑NBP on BDNF and TrkB expression and neurological function of vascular dementia rats. Molecular medicine reports. vol 16. issue 5. 2018-06-06. PMID:28944854. |
l‑nbp may therefore enhance hippocampal expression of bdnf, trkb, akt and nmdar, decrease ischemic injury of vd rats, and improve learning and memory. |
2018-06-06 |
2023-08-13 |
rat |
| Yong Kyoung Yoo, Jaekwang Lee, Jinsik Kim, Gangeun Kim, Sunpil Kim, Jeongyeon Kim, Heejung Chun, Jeong Hoon Lee, C Justin Lee, Kyo Seon Hwan. Ultra-sensitive detection of brain-derived neurotrophic factor (BDNF) in the brain of freely moving mice using an interdigitated microelectrode (IME) biosensor. Scientific reports. vol 6. 2018-06-04. PMID:27640722. |
brain-derived neurotrophic factor (bdnf) plays a critical role in cognitive processes including learning and memory. |
2018-06-04 |
2023-08-13 |
mouse |