| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
these disconnects in the effects of exercise, sex hormones and the combined treatment on behavioral and neurochemical outcomes suggest that a neurochemical mechanism other than hippocampal bdnf might contribute in the ameliorating effects of exercise on learning and memory deficits induced by developmental thyroid hormone insufficiency. |
2021-07-08 |
2023-08-13 |
rat |
| b' Samuel Fleury, Imane Boukhatem, Jessica Le Blanc, M\\xc3\\xa9lanie Welman, Marie Lordkipanidz\\xc3\\xa. Tissue-Specificity of Antibodies Raised Against TrkB and p75 Frontiers in immunology. vol 12. 2021-06-30. PMID:33643311.' |
the brain-derived neurotrophic factor (bdnf) acts as a neuronal growth factor involved in learning and memory through the binding of two receptors, the tropomyosin receptor kinase b (trkb) and the 75 kda pan-neurotrophic receptor (p75 |
2021-06-30 |
2023-08-13 |
Not clear |
| Aaron Johnstone, William Moble. Local TrkB signaling: themes in development and neural plasticity. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32936344. |
as an example, the receptor tyrosine kinase trkb, activated by its ligand brain-derived neurotrophic factor (bdnf), has emerged as a potent modulator of plasticity in both development and adulthood, from neurite pruning and branching events during pns and cns development, to learning and memory. |
2021-06-23 |
2023-08-13 |
Not clear |
| Sara Memarpour, Farimah Beheshti, Yousef Baghcheghi, Abbas Ali Vafaei, Mahmoud Hosseini, Ali Rashidy-Pou. Neuronal Nitric Oxide Inhibitor 7-Nitroindazole Improved Brain-Derived Neurotrophic Factor and Attenuated Brain Tissues Oxidative Damage and Learning and Memory Impairments of Hypothyroid Juvenile Rats. Neurochemical research. vol 45. issue 11. 2021-06-02. PMID:32930947. |
hypothyroidism-associated learning and memory impairment is reported to be connected to oxidative stress and reduced levels of brain-derived neurotrophic factor (bdnf). |
2021-06-02 |
2023-08-13 |
rat |
| Sara Memarpour, Farimah Beheshti, Yousef Baghcheghi, Abbas Ali Vafaei, Mahmoud Hosseini, Ali Rashidy-Pou. Neuronal Nitric Oxide Inhibitor 7-Nitroindazole Improved Brain-Derived Neurotrophic Factor and Attenuated Brain Tissues Oxidative Damage and Learning and Memory Impairments of Hypothyroid Juvenile Rats. Neurochemical research. vol 45. issue 11. 2021-06-02. PMID:32930947. |
the results of the current study showed that 7ni improvement in the learning and memory of the hypothyroid juvenile rats, which was accompanied with improving of bdnf and attenuation of no and brain tissues oxidative damage. |
2021-06-02 |
2023-08-13 |
rat |
| Sanne J E Bruijniks, Gerard van Grootheest, Pim Cuijpers, Hilde de Kluiver, Christiaan H Vinkers, Frenk Peeters, Brenda Penninx, Charlotte E Teunissen, Marcus J H Huiber. Working memory moderates the relation between the brain-derived neurotropic factor (BDNF) and psychotherapy outcome for depression. Journal of psychiatric research. vol 130. 2021-05-14. PMID:32891918. |
bdnf is implicated in learning and memory and may play a role in the effects of psychotherapy that involves changing cognitions and behaviors. |
2021-05-14 |
2023-08-13 |
Not clear |
| Esmaeil Amraie, Iran Pouraboli, Ziba Rajae. Neuroprotective effects of Levisticum officinale on LPS-induced spatial learning and memory impairments through neurotrophic, anti-inflammatory, and antioxidant properties. Food & function. vol 11. issue 7. 2021-05-07. PMID:32648872. |
in conclusion, the beneficial effect of loe on the improvement of learning and memory could be attributed to its anti-inflammatory and antioxidant activities, along with its ability to increase bdnf expression and neurogenesis in the hippocampus. |
2021-05-07 |
2023-08-13 |
rat |
| Farshid Sadegzadeh, Nona Sakhaie, Khatereh Isazadehfar, Hakimeh Saadat. Effects of exposure to enriched environment during adolescence on passive avoidance memory, nociception, and prefrontal BDNF level in adult male and female rats. Neuroscience letters. vol 732. 2021-04-27. PMID:32522604. |
therefore, the present experiment was aimed to assess the effects of ee during adolescence on passive avoidance learning and memory, nociception, and prefrontal cortex (pfc) bdnf mrna levels in the adult male and female rats. |
2021-04-27 |
2023-08-13 |
rat |
| Jinge Xin, Hesong Wang, Ning Sun, Shamsuddin Bughio, Dong Zeng, Lianxin Li, Yanyan Wang, Abdul Khalique, Yan Zeng, Kangcheng Pan, Bo Jing, Hailin Ma, Yang Bai, Xueqin N. Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice. Ecotoxicology and environmental safety. vol 215. 2021-04-20. PMID:33799132. |
moreover, the hippocampus which is essential to learning and memory, down-regulated mrna level of both the myelin-associated glycoprotein (mag), and protein levels of brain-derived neurotrophic factor (bdnf), including the improvement of camp response element-binding protein (creb) by bs15 in fluoride-exposed mice after was. |
2021-04-20 |
2023-08-13 |
mouse |
| Bonan Liu, Jiayuan Kou, Fuyan Li, Da Huo, Jiaran Xu, Xiaoxi Zhou, Dehao Meng, Murtaza Ghulam, Bobkov Artyom, Xu Gao, Ning Ma, Dong Ha. Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase. Aging. vol 12. issue 9. 2021-02-26. PMID:32392535. |
the effects of leo on learning and memory were examined using the morris water maze (mwm) test, novel object recognition test, and correlative indicators, including a neurotransmitter (acetylcholinesterase, ache), a nerve growth factor (brain-derived neurotrophic factor, bdnf), a postsynaptic marker (psd95), and presynaptic markers (synapsin-1, and synaptophysin), in app/ps1 mice. |
2021-02-26 |
2023-08-13 |
mouse |
| Wenzhu Wang, Xu Liu, Zhengyi Yang, Hui Shen, Lixu Liu, Yan Yu, Tong Zhan. Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats. Frontiers in neuroscience. vol 14. 2020-12-18. PMID:33328857. |
the results showed that levodopa improved the neurological function and learning and memory of rats after global cerebral ischemia/reperfusion injury, improved the integrity of white matter, and density of gray matter in the hippocampus, increased the number of synapses, reduced the delayed neuronal death, and increased the expression of synaptic plasticity-related proteins (bdnf, trkb, psd95, and drebrin) in the hippocampus. |
2020-12-18 |
2023-08-13 |
rat |
| Ren-Shi Li, Ryo Fukumori, Tomoki Takeda, Yingxia Song, Satoshi Morimoto, Ruri Kikura-Hanajiri, Taku Yamaguchi, Kazuhito Watanabe, Kousuke Aritake, Yoshitaka Tanaka, Hideyuki Yamada, Tsuneyuki Yamamoto, Yuji Ishi. Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31270353. |
additionally, we showed that jwh-018 causes a reduction in the levels of brain-derived neurotrophic factor (bdnf), which is known to modulate synaptic plasticity and adaptive processes underlying learning and memory. |
2020-10-26 |
2023-08-13 |
Not clear |
| Ren-Shi Li, Ryo Fukumori, Tomoki Takeda, Yingxia Song, Satoshi Morimoto, Ruri Kikura-Hanajiri, Taku Yamaguchi, Kazuhito Watanabe, Kousuke Aritake, Yoshitaka Tanaka, Hideyuki Yamada, Tsuneyuki Yamamoto, Yuji Ishi. Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31270353. |
as both endocannabinoids and bdnf have been shown to modulate learning and memory in the hippocampus, the alteration of their levels in response to jwh-018 may explain the contribution of synthetic cannabinoids to impairment of memory. |
2020-10-26 |
2023-08-13 |
Not clear |
| Miao Li, Aiming Xie, Ya Liu, Qian Zeng, Shucai Huang, Qiuping Huang, Tianli Shao, Xinxin Chen, Zhenjiang Liao, Yi Cai, Zhijie Xiao, Xiaojie Zhang, Hongxian She. Ketamine Administration Leads to Learning-Memory Dysfunction and Decreases Serum Brain-Derived Neurotrophic Factor in Rats. Frontiers in psychiatry. vol 11. 2020-10-23. PMID:33088278. |
this study investigated the effects of acute or chronic ketamine administration on learning and memory function as well as levels of brain-derived neurotrophic factor (bdnf) in the hippocampus and blood in order to explore the potential correlation between learning-memory dysfunction and ketamine. |
2020-10-23 |
2023-08-13 |
rat |
| Mamoru Fukuchi, Yui Okuno, Hironori Nakayama, Aoi Nakano, Hisashi Mori, Satoru Mitazaki, Yuka Nakano, Kazufumi Toume, Michiko Jo, Ichiro Takasaki, Kazuki Watanabe, Naotoshi Shibahara, Katsuko Komatsu, Akiko Tabuchi, Masaaki Tsud. Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31413298. |
brain-derived neurotrophic factor (bdnf) is a key player in synaptic plasticity, and consequently, learning and memory. |
2020-10-22 |
2023-08-13 |
mouse |
| Tao Jiang, Xiu-Qin Wang, Chuan Ding, Xue-Lian D. Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 6. 2020-10-01. PMID:29200900. |
recent studies have indicated that brain-derived neurotrophic factor (bdnf) and cyclic amp response element-binding protein (creb) are involved in learning and memory processes. |
2020-10-01 |
2023-08-13 |
rat |
| Kowsar Bavarsad, Mousa-Al-Reza Hadjzadeh, Mahmoud Hosseini, Roghayeh Pakdel, Farimah Beheshti, Soleyman Bafadam, Zeinab Ashaar. Effects of levothyroxine on learning and memory deficits in a rat model of Alzheimer's disease: the role of BDNF and oxidative stress. Drug and chemical toxicology. vol 43. issue 1. 2020-10-01. PMID:29927658. |
effects of levothyroxine on learning and memory deficits in a rat model of alzheimer's disease: the role of bdnf and oxidative stress. |
2020-10-01 |
2023-08-13 |
rat |
| Liang-Jen Wang, Chih-Ching Wu, Min-Jing Lee, Miao-Chun Chou, Sheng-Yu Lee, Wen-Jiun Cho. Peripheral Brain-Derived Neurotrophic Factor and Contactin-1 Levels in Patients with Attention-Deficit/Hyperactivity Disorder. Journal of clinical medicine. vol 8. issue 9. 2020-10-01. PMID:31480710. |
brain-derived neurotrophic factor (bdnf) facilitates neuronal growth and plasticity, and is crucial for learning and memory. |
2020-10-01 |
2023-08-13 |
Not clear |
| Cai-Xia Zheng, Min Lu, Ya-Bi Guo, Feng-Xia Zhang, Hua Liu, Feng Guo, Xiao-Lin Huang, Xiao-Hua Ha. Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2020-09-30. PMID:27829866. |
ea significantly (1) ameliorated the spatial learning and memory deficits, (2) alleviated long-term potentiation (ltp) impairment and the reduction of dendritic spine density, (3) suppressed the decline of phospho-creb (pcreb) protein, brain-derived neurotrophic factor (bdnf) protein, and microrna132 (mir132), and (4) reduced the increase of p250gap protein of 2vo rats. |
2020-09-30 |
2023-08-13 |
rat |
| Zahiruddin Othman, Rahimah Zakaria, Nik Hazlina Nik Hussain, Asma' Hassan, Nazlahshaniza Shafin, Badriya Al-Rahbi, Asma Hayati Ahma. Potential Role of Honey in Learning and Memory. Medical sciences (Basel, Switzerland). vol 3. issue 2. 2020-09-30. PMID:29083387. |
it is hypothesized that the improvement in learning and memory following tualang honey supplementation is due to the significant improvement in brain morphology and enhancement of brain cholinergic system secondary to reduction in brain oxidative damage and/or upregulation of bdnf concentration. |
2020-09-30 |
2023-08-13 |
human |