| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yukako Kawasaki, Kenichi Oishi, Antonette Hernandez, Thomas Ernst, Dan Wu, Yoshihisa Otsuka, Can Ceritoglu, Linda Chan. Brain-derived neurotrophic factor Val66Met variant on brain volumes in infants. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33474578. |
bdnf is also involved in learning and memory. |
2021-11-02 |
2023-08-13 |
Not clear |
| Jili Zhao, Jinyu Ren, Shuang Liu, Yanan Gong, Ping Meng, Haitao Tan, Yonggang Che. Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway. Experimental and therapeutic medicine. vol 22. issue 6. 2021-11-02. PMID:34721684. |
furthermore, compared with the control group, neonatal exposure to sev reduced the number of neurons and the concentration of bdnf in the hippocampus, a brain region important for learning and memory. |
2021-11-02 |
2023-08-13 |
rat |
| Tomasz Antoni Guzel, Katarzyna Mech, Marek Wroński, Katarzyna Gerkowicz, Agata Bednarczyk, Weronika Adamczyk, Monika Radecka, Maciej Słodkowsk. Brain-derived neurotrophic factor in gastroenterology oncology - short review of current literature. Annals of agricultural and environmental medicine : AAEM. vol 28. issue 3. 2021-10-26. PMID:34558255. |
the hippocampal concentration of bdnf is believed to play an important role in learning and memory, it has a protective role in neurodegeneration and stress responses. |
2021-10-26 |
2023-08-13 |
Not clear |
| Yousef Baghcheghi, Farimah Beheshti, Hossein Salmani, Mahmoud Hossein. Brain‑derived neurotrophic factor and nitric oxide contribute to protective effects of rosiglitazone on learning and memory in hypothyroid rats. Acta neurobiologiae experimentalis. vol 81. issue 3. 2021-10-21. PMID:34672293. |
the effects of the well‑known peroxisome proliferator‑activated receptor gamma (ppar-γ) agonist rosiglitazone (rosi) on brain‑derived neurotrophic factor (bdnf), nitric oxide (no), and learning and memory were investigated in hypothyroid rats. |
2021-10-21 |
2023-08-13 |
rat |
| Yousef Baghcheghi, Farimah Beheshti, Hossein Salmani, Mahmoud Hossein. Brain‑derived neurotrophic factor and nitric oxide contribute to protective effects of rosiglitazone on learning and memory in hypothyroid rats. Acta neurobiologiae experimentalis. vol 81. issue 3. 2021-10-21. PMID:34672293. |
the results of the present study showed that bdnf and no play a role in the protective effects of rosi against learning and memory impairment in hypothyroid rats. |
2021-10-21 |
2023-08-13 |
rat |
| Yao-Ching Fang, Jia-Yu Hsieh, Amelia Nur Vidyanti, Chih-Hao Yang, Jing-Shiun Jan, Kang-Wei Chang, Chaur-Jong Hu, Yong-Kwang T. HDACi protects against vascular cognitive impairment from CCH injury via induction of BDNF-related AMPA receptor activation. Journal of cellular and molecular medicine. vol 25. issue 15. 2021-10-15. PMID:34216182. |
bdnf is involved in cell proliferation and differentiation in development, synaptic plasticity and in learning and memory related with receptors or synaptic proteins. |
2021-10-15 |
2023-08-13 |
mouse |
| Nona Sakhaie, Farshid Sadegzadeh, Raziyeh Dehghany, Omid Adak, Saadati Hakime. Sex-dependent effects of chronic fluoxetine exposure during adolescence on passive avoidance memory, nociception, and prefrontal brain-derived neurotrophic factor mRNA expression. Brain research bulletin. vol 162. 2021-09-29. PMID:32585291. |
therefore, in the present experimental study, we examined the effects of chronic fluoxetine exposure (5 mg/kg/day, gavage) throughout adolescence (postnatal day 21-60) on passive avoidance learning and memory, pain sensitivity, and brain-derived neurotrophic factor (bdnf) level in the prefrontal cortex of young adult male and female rats. |
2021-09-29 |
2023-08-13 |
rat |
| Kadri Seppa, Toomas Jagomäe, Kaia Grete Kukker, Riin Reimets, Marko Pastak, Eero Vasar, Anton Terasmaa, Mario Plaa. Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model. Scientific reports. vol 11. issue 1. 2021-09-15. PMID:33500541. |
glp1 receptor agonist liraglutide and bdnf mimetic 7,8-dihydroxyflavone (7,8-dhf) have had protective effect to visual pathway and to learning and memory in different rat models of neurodegenerative disorders. |
2021-09-15 |
2023-08-13 |
rat |
| Narges Marefati, Farimah Beheshti, Sara Memarpour, Reza Bayat, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Hamed Ghazavi, Mahmoud Hossein. The effects of acetyl-11-keto-β-boswellic acid on brain cytokines and memory impairment induced by lipopolysaccharide in rats. Cytokine. vol 131. 2021-09-08. PMID:32380425. |
akba effectively ameliorated lps-induced learning and memory impairments and improved bdnf in a neuroinflammation animal model. |
2021-09-08 |
2023-08-13 |
rat |
| Yulong Wu, Fangfang Deng, Jian Wang, Yaping Liu, Wei Zhou, Lei Qu, Mei Chen. Intensity-dependent effects of consecutive treadmill exercise on spatial learning and memory through the p-CREB/BDNF/NMDAR signaling in hippocampus. Behavioural brain research. vol 386. 2021-08-24. PMID:32184158. |
in this study, we aimed to explore the effects of exercise intensity on spatial learning and memory, as well as the regulation of brain-derived neurotrophic factor (bdnf)/p-creb/nmdar signal. |
2021-08-24 |
2023-08-13 |
rat |
| Fatemeh Mansouri, Hamideh Ghanbari, Narges Marefati, Zohre Arab, Hossein Salmani, Farimah Beheshti, Mahmoud Hossein. Protective effects of vitamin D on learning and memory deficit induced by scopolamine in male rats: the roles of brain-derived neurotrophic factor and oxidative stress. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 7. 2021-08-19. PMID:33649977. |
in the current research, the protective effects of vit d on learning and memory deficit induced by scopolamine, oxidative stress criteria, brain-derived neurotrophic factor (bdnf), and nitric oxide (no) in the brain were investigated. |
2021-08-19 |
2023-08-13 |
rat |
| Fatemeh Mansouri, Hamideh Ghanbari, Narges Marefati, Zohre Arab, Hossein Salmani, Farimah Beheshti, Mahmoud Hossein. Protective effects of vitamin D on learning and memory deficit induced by scopolamine in male rats: the roles of brain-derived neurotrophic factor and oxidative stress. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 7. 2021-08-19. PMID:33649977. |
the results demonstrated that vit d has protective effects on scopolamine-associated learning and memory impairment by improving bdnf levels and attenuating no and brain tissue oxidative damage. |
2021-08-19 |
2023-08-13 |
rat |
| Yunxia Dong, Wei Hong, Zhiyin Tang, Yan Gao, Xiuying Wu, Hongtao Li. Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1. Neurochemistry international. vol 139. 2021-08-11. PMID:32650025. |
this study investigated the effects of multiple inhalations of sevoflurane on long-term learning and memory in developing rats, and explored the mechanistic role of the tissue plasminogen activator (tpa)/plasminogen activator inhibitor-1 (pai-1) fibrinolysis system and its regulatory relationship with the brain derived neurotrophic factor (bdnf) by activation of tropomysin related kinase b (trkb). |
2021-08-11 |
2023-08-13 |
rat |
| Yunxia Dong, Wei Hong, Zhiyin Tang, Yan Gao, Xiuying Wu, Hongtao Li. Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1. Neurochemistry international. vol 139. 2021-08-11. PMID:32650025. |
the results showed multiple inhalation of sevoflurane led to learning and memory dysfunction, downregulated the expression of the synaptic-related proteins, decreased dendritic spine density in the hippocampus, increased the expression level of probdnf and pai-1, and reduced expression of bdnf, tpa, and p-trkb. |
2021-08-11 |
2023-08-13 |
rat |
| Yunxia Dong, Wei Hong, Zhiyin Tang, Yan Gao, Xiuying Wu, Hongtao Li. Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1. Neurochemistry international. vol 139. 2021-08-11. PMID:32650025. |
therefore, sevoflurane exposure could lead to learning and memory dysfunction by inhibiting bdnf cleavage via breaking the balance of tpa/pai-1. |
2021-08-11 |
2023-08-13 |
rat |
| Mohadeseh Ghalandari-Shamami, Shahla Nourizade, Mehdi Barati, Behpour Yousefi, Mehrnush Pashayi, Abbas Ali Vafaei, Parviz Kokhaei, Ali Rashidy-Pou. Exercise and crocin prevent adolescent-stress induced impairment of spatial navigation and dendritic retraction in the hippocampal CA3 area in adult male rats. Brain research. vol 1754. 2021-07-22. PMID:33422526. |
following the interventions, plasma levels of corticosterone, spatial learning and memory, apical dendritic length of ca3 pyramidal neurons and bdnf levels in the ca3 area were assessed. |
2021-07-22 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
given the well-known effects of physical activity and sex hormones on cognitive functions and brain-derived neurotrophic factor (bdnf), the present study examined the effects of treadmill exercise, sex hormones, and the combined treatment on learning and memory and hippocampal bdnf levels in transient congenital hypothyroid rats. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
on pnds 48-55, spatial learning and memory of all rats tested in the water maze, which followed by measurement of bdnf in the hippocampus. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
results showed that developmental hypothyroidism induced significant deficits in spatial learning and memory and hippocampal bdnf in both male and female rats. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
in both male and female hypothyroid rats, exercise and exercise plus sex hormones, but not sex hormones alone alleviated learning and memory deficits and all treatments (exercise, sex hormones, and the combined treatment) increased hippocampal bdnf. |
2021-07-08 |
2023-08-13 |
rat |