| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bombi Lee, Bongjun Sur, Seong-Guk Cho, Mijung Yeom, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration. Biomolecules & therapeutics. vol 23. issue 6. 2015-11-04. PMID:26535083. |
thus, bas may be an effective therapeutic for learning and memory disturbances, and its neuroprotective effect was mediated, in part, by normalizing the cort response, resulting in regulation of bdnf and creb functions and anti-apoptosis in rats. |
2015-11-04 |
2023-08-13 |
rat |
| Min-Kyoo Shin, Hong-Gi Kim, Kil-Lyong Ki. A novel brain-derived neurotrophic factor-modulating peptide attenuates Aβ1-42-induced neurotoxicity in vitro. Neuroscience letters. vol 595. 2015-10-20. PMID:25849526. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophin family, which plays important roles in learning and memory formation and in protecting neurons from diverse neurotoxic insults, such as amyloid-beta (aβ). |
2015-10-20 |
2023-08-13 |
rat |
| Y W C Wu, X Du, M van den Buuse, R A Hil. Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol. Translational psychiatry. vol 5. 2015-09-09. PMID:25603414. |
brain-derived neurotrophic factor (bdnf) regulates learning and memory and its expression is highly responsive to estradiol. |
2015-09-09 |
2023-08-13 |
mouse |
| Y W C Wu, X Du, M van den Buuse, R A Hil. Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol. Translational psychiatry. vol 5. 2015-09-09. PMID:25603414. |
what is unknown is whether disruptions to the aforementioned estradiol-parvalbumin pathway alter learning and memory, and whether bdnf may mediate these events. |
2015-09-09 |
2023-08-13 |
mouse |
| Maryam Radahmadi, Hojjatallah Alaei, Mohammad Reza Sharifi, Nasrin Hossein. Effects of different timing of stress on corticosterone, BDNF and memory in male rats. Physiology & behavior. vol 139. 2015-08-31. PMID:25481360. |
the present study investigated the effects of chronic stress before, after, and during learning on the changes of learning and memory, on serum and hippocampal levels of corticosterone (cort), brain-derived neurotrophic factor (bdnf) and body weight in rats. |
2015-08-31 |
2023-08-13 |
rat |
| Dexiang Liu, Zhen Wang, Ze Gao, Kai Xie, Qingrui Zhang, Hong Jiang, Qi Pan. Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress. Behavioural brain research. vol 271. 2015-08-06. PMID:24914461. |
effects of curcumin on learning and memory deficits, bdnf, and erk protein expression in rats exposed to chronic unpredictable stress. |
2015-08-06 |
2023-08-13 |
rat |
| Huiying Liu, Jinghua Yang, Qiufang Liu, Cuihong Jin, Shengwen Wu, Xiaobo Lu, Linlin Zheng, Qi Xi, Yuan Ca. Lanthanum chloride impairs spatial memory through ERK/MSK1 signaling pathway of hippocampus in rats. Neurochemical research. vol 39. issue 12. 2015-08-04. PMID:25316495. |
lacl3 considerably impaired the spatial learning and memory of rats in the morris water maze test, damaged the synaptic ultrastructure and downregulated the expression of p-mek1/2, p-erk1/2, p-msk1, p-creb, c-fos and bdnf in the hippocampus. |
2015-08-04 |
2023-08-13 |
rat |
| Chunhong Liang, Shimei Tan, Quanfang Huang, Jun Lin, Zhongpeng Lu, Xing Li. Pratensein ameliorates β-amyloid-induced cognitive impairment in rats via reducing oxidative damage and restoring synapse and BDNF levels. Neuroscience letters. vol 592. 2015-07-15. PMID:25748315. |
these results indicate that pratensein could significantly ameliorate aβ1-42-induced spatial learning and memory impairment through reducing neuroinflammation via inhibition of glial activation and nf-κb activation, and restoring synapse and bdnf levels, suggesting that administration of pratensein could likely provide a therapeutic approach for ad. |
2015-07-15 |
2023-08-13 |
rat |
| Tina B Lonsdorf, Armita Golkar, Kara M Lindström, Jan Haaker, Arne Öhman, Martin Schalling, Martin Ingva. BDNFval66met affects neural activation pattern during fear conditioning and 24 h delayed fear recall. Social cognitive and affective neuroscience. vol 10. issue 5. 2015-07-09. PMID:25103087. |
in both rodents and humans, bdnf has been implicated in hippocampus- and amygdala-dependent learning and memory and has more recently been linked to fear extinction processes. |
2015-07-09 |
2023-08-13 |
human |
| Jin Sun, Yunxia Qu, Huiming He, Xiaolei Fan, Yuanhua Qin, Weifeng Mao, Lixin X. Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25241777. |
these findings showed that polydatin had a protective effect against learning and memory impairment in neonatal rats with hibi and that the protective effect may be mediated through the upregulation of bdnf. |
2015-06-19 |
2023-08-13 |
rat |
| Tae-Woon Kim, Hyun-Sik Kang, Joon-Ki Park, Sam-Jun Lee, Sang-Bin Baek, Chang-Ju Ki. Voluntary wheel running ameliorates symptoms of MK-801-induced schizophrenia in mice. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25323073. |
brain‑derived neurotrophic factor (bdnf) is a member of the neurotrophin family and is implicated in learning and memory processes. |
2015-06-19 |
2023-08-13 |
mouse |
| Bao-long Pan, Qiao Niu, Ling Zhan. [Effects of chronic aluminum exposure on learning and memory and brain-derived nerve growth factor in rats]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 31. issue 10. 2015-04-22. PMID:24148950. |
to investigate the effects of chronic aluminum exposure on the learning and memory abilities and brain-derived nerve growth factor (bdnf) in sprague-dawley (sd) rats. |
2015-04-22 |
2023-08-12 |
rat |
| Iva Dincheva, Siobhan S Pattwell, Lino Tessarollo, Kevin G Bath, Francis S Le. BDNF modulates contextual fear learning during adolescence. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24992985. |
brain-derived neurotrophic factor (bdnf) is a growth factor that plays key roles in regulating higher-order emotional and cognitive processes including fear learning and memory. |
2015-04-17 |
2023-08-13 |
mouse |
| Paolo Ghisletta, Lars Bäckman, Lars Bertram, Andreas Markus Brandmaier, Denis Gerstorf, Tian Liu, Ulman Lindenberge. The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults. Psychology and aging. vol 29. issue 2. 2015-03-18. PMID:24660789. |
the brain-derived neurotrophic factor (bdnf) promotes activity-dependent synaptic plasticity, and contributes to learning and memory. |
2015-03-18 |
2023-08-12 |
human |
| Yu Zhao, Ming Xiao, Wenbo He, Zhiyou Ca. Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits. Neuropsychiatric disease and treatment. vol 11. 2015-03-09. PMID:25750531. |
the aim of this study was to investigate the effect of cerebral ischemia on learning and memory as well as on the levels of creb, phosphorylated creb (pcreb), and bdnf, and to determine the effect of minocycline on creb, pcreb, bdnf, and behavioral functional recovery after cerebral ischemia. |
2015-03-09 |
2023-08-13 |
rat |
| André Jerónimo-Santos, Vânia L Batalha, Christa E Müller, Younis Baqi, Ana Maria Sebastião, Luisa V Lopes, Maria José Diógene. Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP. Neuropharmacology. vol 83. 2015-01-29. PMID:24747180. |
brain-derived neurotrophic factor (bdnf) through the activation of its receptor (trkb-fl) exert well-described neuroprotective effects playing a major role in hippocampal synaptic transmission and plasticity such as long-term potentiation (ltp), a molecular surrogate for learning and memory. |
2015-01-29 |
2023-08-13 |
rat |
| Yu Song, Taizhen Cui, Na Xie, Xiaoyi Zhang, Zhibin Qian, Juyuan Li. Protocatechuic acid improves cognitive deficits and attenuates amyloid deposits, inflammatory response in aged AβPP/PS1 double transgenic mice. International immunopharmacology. vol 20. issue 1. 2014-12-28. PMID:24667368. |
the present study provided confirmatory evidence that pca significantly decreased aβ deposits, app and inflammatory response, whereas increased learning and memory ability, as well as enhanced bdnf level. |
2014-12-28 |
2023-08-12 |
mouse |
| Andreas Mühlberger, Marta Andreatta, Heike Ewald, Evelyn Glotzbach-Schoon, Christian Tröger, Christian Baumann, Andreas Reif, Jürgen Deckert, Paul Paul. The BDNF Val66Met polymorphism modulates the generalization of cued fear responses to a novel context. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24247044. |
brain-derived neurotrophic factor (bdnf) has a crucial role in activity-dependent synaptic plasticity and learning and memory. |
2014-12-01 |
2023-08-12 |
human |
| Chang-Yul Kim, Gil-Yong Lee, Gyu Hwan Park, Jongwon Lee, Jung-Hee Jan. Protective Effect of Arabinoxylan against Scopolamine-Induced Learning and Memory Impairment. Biomolecules & therapeutics. vol 22. issue 5. 2014-11-21. PMID:25414779. |
therefore, our findings suggest that ax can improve sco-induced learning and memory impairment possibly through activation of creb and up-regulation of bdnf levels, thereby exhibiting a cognition-enhancing potential. |
2014-11-21 |
2023-08-13 |
rat |
| Jenq-Lin Yang, Yu-Ting Lin, Pei-Chin Chuang, Vilhelm A Bohr, Mark P Mattso. BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1. Neuromolecular medicine. vol 16. issue 1. 2014-10-28. PMID:24114393. |
brain-derived neurotrophic factor (bdnf) promotes the survival and growth of neurons during brain development and mediates activity-dependent synaptic plasticity and associated learning and memory in the adult. |
2014-10-28 |
2023-08-12 |
mouse |