| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Kyoo Shin, Hong-Gi Kim, Seung-Hyun Baek, Woo-Ram Jung, Dong-Ik Park, Jong-Sung Park, Dong-Gyu Jo, Kil-Lyong Ki. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. Neurobiology of aging. vol 35. issue 5. 2014-10-06. PMID:24268884. |
abnormalities in the expression of brain-derived neurotrophic factor (bdnf), which plays an important role in learning and memory formation, have been reported in the brains of ad patients. |
2014-10-06 |
2023-08-12 |
mouse |
| B Lu, G Nagappan, Y L. BDNF and synaptic plasticity, cognitive function, and dysfunction. Handbook of experimental pharmacology. vol 220. 2014-08-26. PMID:24668475. |
indeed, numerous studies firmly established that bdnf plays a critical role in hippocampal long-term potentiation (ltp), a long-term enhancement of synaptic efficacy thought to underlie learning and memory. |
2014-08-26 |
2023-08-12 |
Not clear |
| Graciano Leal, Diogo Comprido, Carlos B Duart. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23602987. |
in this review we discuss the recent progress in understanding the mechanisms contributing to the short- and long-term regulation of the synaptic proteome by bdnf, and the role in synaptic plasticity, which is likely to influence learning and memory formation. |
2014-08-06 |
2023-08-12 |
Not clear |
| Donna L Korol, Paul E Gold, Claire J Scavuzz. Use it and boost it with physical and mental activity. Hippocampus. vol 23. issue 11. 2014-06-23. PMID:23996382. |
in this article, we review evidence for cognitive priming with physical and mental exercise through a memory systems lens and present brain-derived neurotrophic factor (bdnf) signaling as one candidate neural mechanism for experience-dependent modulation of learning and memory. |
2014-06-23 |
2023-08-12 |
Not clear |
| Y P Tang, J Wad. Developmental changes in BDNF protein in the song control nuclei of zebra finches. Neuroscience. vol 250. 2014-04-04. PMID:23920158. |
brain derived neurotrophic factor (bdnf) plays a crucial role in numerous aspects of vertebrate brain development and function, including neurogenesis, cell survival, growth of axonal projections, synaptogenesis and processes linked to learning and memory. |
2014-04-04 |
2023-08-12 |
Not clear |
| Smita Jain, Basu Dev Banerjee, Rafat Sultana Ahmed, Vinod Kumar Arora, Pramod Kumari Mediratt. Possible role of oxidative stress and brain derived neurotrophic factor in triazophos induced cognitive impairment in rats. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23949197. |
the study concludes that chronic exposure to tz significantly impairs the learning and memory which may be attributed to the significantly reduced mrna and protein expression of bdnf in hippocampus. |
2014-03-28 |
2023-08-12 |
rat |
| M M Yin, W Wang, J Sun, S Liu, X L Liu, Y M Niu, H R Yuan, F Y Yang, L F. Paternal treadmill exercise enhances spatial learning and memory related to hippocampus among male offspring. Behavioural brain research. vol 253. 2014-03-18. PMID:23916757. |
in this study we attempt to determine the effects of 6 weeks paternal treadmill exercise on spatial learning and memory and the expression of brain-derived neurotrophic factor (bdnf) and reelin in their male offspring. |
2014-03-18 |
2023-08-12 |
mouse |
| M M Yin, W Wang, J Sun, S Liu, X L Liu, Y M Niu, H R Yuan, F Y Yang, L F. Paternal treadmill exercise enhances spatial learning and memory related to hippocampus among male offspring. Behavioural brain research. vol 253. 2014-03-18. PMID:23916757. |
our results showed that paternal treadmill exercise improved the spatial learning and memory capability of male pups, which was accompanied by significantly increased expression of bdnf and reelin, as compared to those of c group. |
2014-03-18 |
2023-08-12 |
mouse |
| Hiroji Yanamoto, Yukako Nakajo, Hiroharu Kataoka, Koji Iihar. High voltage electric potentials to enhance brain-derived neurotrophic factor levels in the brain. Frontiers of neurology and neuroscience. vol 32. 2014-03-12. PMID:23859972. |
development of a safe method to increase brain-derived neurotrophic factor (bdnf) levels in the brain is expected to enhance learning and memory, induce tolerance to cerebral infarction or tolerance to depressive state, improve glucose metabolism, and suppress appetite and body weight. |
2014-03-12 |
2023-08-12 |
mouse |
| Hiroji Yanamoto, Yukako Nakajo, Hiroharu Kataoka, Koji Iihar. High voltage electric potentials to enhance brain-derived neurotrophic factor levels in the brain. Frontiers of neurology and neuroscience. vol 32. 2014-03-12. PMID:23859972. |
we have shown that repetitive applications of high-voltage electric potential (help) to the body increase bdnf levels in the brain, improving learning and memory in mice. |
2014-03-12 |
2023-08-12 |
mouse |
| Christopher N Parkhurst, Guang Yang, Ipe Ninan, Jeffrey N Savas, John R Yates, Juan J Lafaille, Barbara L Hempstead, Dan R Littman, Wen-Biao Ga. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell. vol 155. issue 7. 2014-02-26. PMID:24360280. |
together, our findings reveal that microglia serve important physiological functions in learning and memory by promoting learning-related synapse formation through bdnf signaling. |
2014-02-26 |
2023-08-12 |
mouse |
| Tomi Rantamäki, Susanna Kemppainen, Henri Autio, Saara Stavén, Hennariikka Koivisto, Masami Kojima, Hanna Antila, Pasi O Miettinen, Elisa Kärkkäinen, Nina Karpova, Liisa Vesa, Lothar Lindemann, Marius C Hoener, Heikki Tanila, Eero Castré. The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PloS one. vol 8. issue 7. 2014-02-07. PMID:23844236. |
brain-derived neurotrophic factor (bdnf) importantly regulates learning and memory and supports the survival of injured neurons. |
2014-02-07 |
2023-08-12 |
mouse |
| Tomi Rantamäki, Susanna Kemppainen, Henri Autio, Saara Stavén, Hennariikka Koivisto, Masami Kojima, Hanna Antila, Pasi O Miettinen, Elisa Kärkkäinen, Nina Karpova, Liisa Vesa, Lothar Lindemann, Marius C Hoener, Heikki Tanila, Eero Castré. The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PloS one. vol 8. issue 7. 2014-02-07. PMID:23844236. |
if similar bdnf accumulation happens in human ad brains, it would suggest that functional bdnf levels in the ad brains are even lower than reported, which could partially contribute to learning and memory problems of ad patients. |
2014-02-07 |
2023-08-12 |
mouse |
| Cameron S Mang, Kristin L Campbell, Colin J D Ross, Lara A Boy. Promoting neuroplasticity for motor rehabilitation after stroke: considering the effects of aerobic exercise and genetic variation on brain-derived neurotrophic factor. Physical therapy. vol 93. issue 12. 2014-01-30. PMID:23907078. |
converging evidence demonstrates that aerobic exercise increases bdnf production and consequently enhances learning and memory processes. |
2014-01-30 |
2023-08-12 |
Not clear |
| Laura Psotta, Volkmar Lessmann, Thomas Endre. Impaired fear extinction learning in adult heterozygous BDNF knock-out mice. Neurobiology of learning and memory. vol 103. 2014-01-24. PMID:23578839. |
brain-derived neurotrophic factor (bdnf) is a crucial regulator of neuroplasticity, which underlies learning and memory processes in different brain areas. |
2014-01-24 |
2023-08-12 |
mouse |
| Min Meng, Xinhan Zhao, Yonghui Dang, Jingyuan Ma, Lixu Li, Shanzhi G. Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice. Brain research. vol 1519. 2014-01-23. PMID:23623815. |
furthermore, bdnf splice variants ii, iv and vi may play a role in learning and memory for morphine addiction in the hippocampus, cpu and nacc. |
2014-01-23 |
2023-08-12 |
mouse |
| Davide Carlino, Maurizio De Vanna, Enrico Tongiorg. Is altered BDNF biosynthesis a general feature in patients with cognitive dysfunctions? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 19. issue 4. 2013-12-31. PMID:23242909. |
bdnf undergoes proteolytic processing and studies in animal models have highlighted that different forms of learning and memory require either the probdnf precursor or the mature bdnf form. |
2013-12-31 |
2023-08-12 |
Not clear |
| William C Wetsel, Ramona M Rodriguiz, Johann Guillemot, Estelle Rousselet, Rachid Essalmani, Il Hwan Kim, Jesse C Bryant, Jadwiga Marcinkiewicz, Roxane Desjardins, Robert Day, Daniel B Constam, Annik Prat, Nabil G Seida. Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 43. 2013-12-30. PMID:24101515. |
disruption of the expression of the proprotein convertase pc7 reduces bdnf production and affects learning and memory in mice. |
2013-12-30 |
2023-08-12 |
mouse |
| Andrea Gómez-Palacio-Schjetnan, Martha L Escoba. Neurotrophins and synaptic plasticity. Current topics in behavioral neurosciences. vol 15. 2013-11-19. PMID:23519767. |
among these, brain-derived neurotrophic factor (bdnf) as well as neurotrophin-3 (nt-3) have emerged as having key roles in the neurobiological mechanisms related to learning and memory. |
2013-11-19 |
2023-08-12 |
Not clear |
| Dong Wan, Lijun Xue, Huifeng Zhu, Yong Lu. Catalpol Induces Neuroprotection and Prevents Memory Dysfunction through the Cholinergic System and BDNF. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-11-06. PMID:24194776. |
morris water maze was employed to investigate its effects on learning and memory and then clarify its possible mechanisms relating the central cholinergic system and bdnf. |
2013-11-06 |
2023-08-12 |
mouse |