| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iva Dincheva, Charles E Glatt, Francis S Le. Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 18. issue 5. 2013-03-05. PMID:22367929. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophin growth factor family and is implicated as a modulator of neuronal survival and differentiation, synaptic plasticity, and higher order cognitive functions such as learning and memory. |
2013-03-05 |
2023-08-12 |
mouse |
| Iva Dincheva, Charles E Glatt, Francis S Le. Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 18. issue 5. 2013-03-05. PMID:22367929. |
in this review, the authors discuss the impact of the bdnf snp on learning and memory while providing arguments for the relevance of a vertically integrated approach to studying human genetic variants. |
2013-03-05 |
2023-08-12 |
mouse |
| S-Y Yau, B W-M Lau, E-D Zhang, J C-D Lee, A Li, T M C Lee, Y-P Ching, A-M Xu, K-F S. Effects of voluntary running on plasma levels of neurotrophins, hippocampal cell proliferation and learning and memory in stressed rats. Neuroscience. vol 222. 2013-01-24. PMID:22813995. |
we examined the effects of acute (5 days) and chronic (4 weeks) treatment with cort and/or wheel running on (1) hippocampal cell proliferation, (2) spatial learning and memory and (3) plasma levels of bdnf and igf-1. |
2013-01-24 |
2023-08-12 |
rat |
| Fei Zheng, Xianju Zhou, Changjong Moon, Hongbing Wan. Regulation of brain-derived neurotrophic factor expression in neurons. International journal of physiology, pathophysiology and pharmacology. vol 4. issue 4. 2013-01-16. PMID:23320132. |
brain-derived neurotrophic factor (bdnf) plays critical roles in many aspects of brain functions, including cell survival, differentiation, development, learning and memory. |
2013-01-16 |
2023-08-12 |
Not clear |
| Kwok-On Lai, Alan S L Wong, Man-Chun Cheung, Pei Xu, Zhuoyi Liang, Ka-Chun Lok, Hui Xie, Mary E Palko, Wing-Ho Yung, Lino Tessarollo, Zelda H Cheung, Nancy Y I. TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory. Nature neuroscience. vol 15. issue 11. 2013-01-03. PMID:23064382. |
the neurotrophin brain-derived neurotrophic factor (bdnf) and its receptor trkb participate in diverse neuronal functions, including activity-dependent synaptic plasticity that is crucial for learning and memory. |
2013-01-03 |
2023-08-12 |
mouse |
| Ruud Smolders, Mark Rijpkema, Barbara Franke, Guillén Fernánde. BDNF Val66Met polymorphism interacts with sex to influence bimanual motor control in healthy humans. Brain and behavior. vol 2. issue 6. 2012-11-22. PMID:23170235. |
a common single nucleotide polymorphism in the gene encoding bdnf (rs6265, val66met) affects bdnf release and has been associated with altered learning and memory performance, and with structural changes in brain morphology and corpus callosum integrity. |
2012-11-22 |
2023-08-12 |
human |
| R Andero, K J Ressle. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22530815. |
brain-derived neurotrophic factor (bdnf) is the most studied neurotrophin involved in synaptic plasticity processes that are required for long-term learning and memory. |
2012-11-20 |
2023-08-12 |
Not clear |
| Xiang Yang Zhang, Jun Liang, Da Chun Chen, Mei Hong Xiu, Fu De Yang, Therese A Kosten, Thomas R Koste. Low BDNF is associated with cognitive impairment in chronic patients with schizophrenia. Psychopharmacology. vol 222. issue 2. 2012-11-16. PMID:22274000. |
several lines of evidence suggest that brain-derived neurotrophic factor (bdnf) plays a critical role in activity-dependent neuroplasticity underlying learning and memory in the hippocampus. |
2012-11-16 |
2023-08-12 |
Not clear |
| Olga Carretón, Albert Giralt, Jesús F Torres-Peraza, Verónica Brito, José J Lucas, Sílvia Ginés, Josep M Canals, Jordi Alberc. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental neurology. vol 237. issue 2. 2012-11-13. PMID:22776425. |
brain-derived neurotrophic factor (bdnf) is a key player in learning and memory processes. |
2012-11-13 |
2023-08-12 |
mouse |
| Timothy C Durazzo, Kent E Hutchison, Susanna L Fryer, Anderson Mon, Dieter J Meyerhof. Associations of Cigarette Smoking and Polymorphisms in Brain-Derived Neurotrophic Factor and Catechol-O-Methyltransferase with Neurocognition in Alcohol Dependent Individuals during Early Abstinence. Frontiers in pharmacology. vol 3. 2012-10-23. PMID:23087644. |
after controlling for comt and bdnf genotypes, smoking alc performed significantly worse than non-smoking alc on the domains of auditory-verbal and visuospatial learning and memory, cognitive efficiency, general intelligence, processing speed, and global neurocognition. |
2012-10-23 |
2023-08-12 |
human |
| Nicola Kuczewski, Christophe Porcher, Volkmar Lessmann, Igor Medina, Jean-Luc Gaiars. Back-propagating action potential: A key contributor in activity-dependent dendritic release of BDNF. Communicative & integrative biology. vol 1. issue 2. 2012-10-02. PMID:19704877. |
brain derived neurotrophic factor (bdnf) is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. |
2012-10-02 |
2023-08-12 |
Not clear |
| Margaret Fahnestock, Monica Marchese, Elizabeth Head, Viorela Pop, Bernadeta Michalski, William N Milgram, Carl W Cotma. BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog. Neurobiology of aging. vol 33. issue 3. 2012-09-28. PMID:20447733. |
we examined the hypothesis that an increase in levels of brain-derived neurotrophic factor (bdnf) is one of the factors underlying improvements in learning and memory. |
2012-09-28 |
2023-08-12 |
dog |
| Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
we found that learning and memory level in the ghrelin treatment group improved significantly, expression of bcl-xl, bdnf, creb, p-creb, and p-erk1/2 in the hippocampus was increased in the ghrelin treatment group, and the number of apoptotic neurons in the hippocampus decreased remarkably. |
2012-08-13 |
2023-08-12 |
rat |
| Shinji Yamaguchi, Naoya Aoki, Daisuke Kobayashi, Takaaki Kitajima, Eiji Iikubo, Sachiko Katagiri, Toshiya Matsushima, Koichi J Homm. Activation of brain-derived neurotrophic factor/tropomyosin-related kinase B signaling accompanying filial imprinting in domestic chicks (Gallus gallus domesticus). Neuroreport. vol 22. issue 17. 2012-08-08. PMID:22015740. |
brain-derived neurotrophic factor (bdnf) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. |
2012-08-08 |
2023-08-12 |
chicken |
| M E Hopkins, R Nitecki, D J Bucc. Physical exercise during adolescence versus adulthood: differential effects on object recognition memory and brain-derived neurotrophic factor levels. Neuroscience. vol 194. 2012-06-25. PMID:21839807. |
it is well established that physical exercise can enhance hippocampal-dependent forms of learning and memory in laboratory animals, commensurate with increases in hippocampal neural plasticity (brain-derived neurotrophic factor [bdnf] mrna/protein, neurogenesis, long-term potentiation [ltp]). |
2012-06-25 |
2023-08-12 |
rat |
| Camin Dean, Huisheng Liu, Thorsten Staudt, Markus A Stahlberg, Siv Vingill, Johanna Bückers, Dirk Kamin, Johann Engelhardt, Meyer B Jackson, Stefan W Hell, Edwin R Chapma. Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 16. 2012-06-12. PMID:22514304. |
bdnf plays a critical role in the regulation of synaptic strength and is essential for long-term potentiation, a phenomenon that underlies learning and memory. |
2012-06-12 |
2023-08-12 |
mouse |
| Maria J Diógenes, Ana R Costenla, Luísa V Lopes, André Jerónimo-Santos, Vasco C Sousa, Bruno M Fontinha, Joaquim A Ribeiro, Ana M Sebastiã. Enhancement of LTP in aged rats is dependent on endogenous BDNF. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 9. 2012-05-08. PMID:21525862. |
long-term potentiation (ltp), considered the neurophysiological basis for learning and memory, is facilitated by brain-derived neurotrophic factor (bdnf), an action more evident when ltp is evoked by weak θ-burst stimuli and dependent on co-activation of adenosine a(2a) receptors (a(2a)r), which are more expressed in aged rats. |
2012-05-08 |
2023-08-12 |
rat |
| Aderbal S Aguiar, Adalberto A Castro, Eduardo L Moreira, Viviane Glaser, Adair R S Santos, Carla I Tasca, Alexandra Latini, Rui D S Predige. Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and BDNF signaling. Mechanisms of ageing and development. vol 132. issue 11-12. 2012-04-30. PMID:21983475. |
short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via akt, creb and bdnf signaling. |
2012-04-30 |
2023-08-12 |
human |
| Hossein Miladi-Gorji, Ali Rashidy-Pour, Yaghoub Fathollahi, Maziar M Akhavan, Saeed Semnanian, Manouchehr Safar. Voluntary exercise ameliorates cognitive deficits in morphine dependent rats: the role of hippocampal brain-derived neurotrophic factor. Neurobiology of learning and memory. vol 96. issue 3. 2012-02-22. PMID:21872672. |
if an effect of exercise was observed, we aimed to investigate the possible role of hippocampal brain-derived neurotrophic factor (bdnf) in the exercise-induced enhancement of learning and memory in morphine-dependent rats. |
2012-02-22 |
2023-08-12 |
rat |
| Pedro Bekinschtein, Charlotte A Oomen, Lisa M Saksida, Timothy J Busse. Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable? Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21767656. |
effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: bdnf as a critical variable? |
2012-01-26 |
2023-08-12 |
Not clear |