Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Davide Carlino, Emiliano Leone, Francesco Di Cola, Gabriele Baj, Raffaella Marin, Giacomo Dinelli, Enrico Tongiorgi, Maurizio De Vann. Low serum truncated-BDNF isoform correlates with higher cognitive impairment in schizophrenia. Journal of psychiatric research. vol 45. issue 2. 2011-04-25. PMID:20630543. |
brain-derived neurotrophic factor (bdnf) is a key factor in learning and memory. |
2011-04-25 |
2023-08-12 |
Not clear |
Antonella Caccamo, Monica A Maldonado, Alex F Bokov, Smita Majumder, Salvatore Odd. CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 52. 2011-03-01. PMID:21149712. |
cbp gene transfer increases bdnf levels and ameliorates learning and memory deficits in a mouse model of alzheimer's disease. |
2011-03-01 |
2023-08-12 |
mouse |
Min Kyoo Shin, Hong Gi Kim, Kil Lyong Ki. A novel trimeric peptide, Neuropep-1-stimulating brain-derived neurotrophic factor expression in rat brain improves spatial learning and memory as measured by the Y-maze and Morris water maze. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21044076. |
to evaluate improvement of spatial learning and memory (slm) by neuropep-1-induced bdnf up-regulation, the y-maze and morris water maze tests were performed. |
2011-01-20 |
2023-08-12 |
rat |
Min Kyoo Shin, Hong Gi Kim, Kil Lyong Ki. A novel trimeric peptide, Neuropep-1-stimulating brain-derived neurotrophic factor expression in rat brain improves spatial learning and memory as measured by the Y-maze and Morris water maze. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21044076. |
therefore, our findings represent that neuropep-1 might be a potential candidate for treatment of learning and memory disorders as well as neurological diseases involving the abnormal expression of bdnf. |
2011-01-20 |
2023-08-12 |
rat |
Yusuke Tozuka, Mami Kumon, Etsuko Wada, Masafumi Onodera, Hideki Mochizuki, Keiji Wad. Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20538025. |
bdnf has been shown to play crucial roles in neuronal differentiation, plasticity and hippocampus-dependent cognitive functions such as spatial learning and memory. |
2010-11-04 |
2023-08-12 |
mouse |
Kristina F Zdanys, Timothy G Kleiman, Huiping Zhang, Fatih Ozbay, Martha G MacAvoy, Joel Gelernter, Christopher H van Dyc. BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study. Journal of Alzheimer's disease : JAD. vol 17. issue 4. 2010-09-22. PMID:19542613. |
the role of bdnf in learning and memory suggests that it may also modulate the clinical course of alzheimer's disease (ad). |
2010-09-22 |
2023-08-12 |
human |
Shu-Chen Li, Christian Chicherio, Lars Nyberg, Timo von Oertzen, Irene E Nagel, Goran Papenberg, Thomas Sander, Hauke R Heekeren, Ulman Lindenberger, Lars Bäckma. Ebbinghaus revisited: influences of the BDNF Val66Met polymorphism on backward serial recall are modulated by human aging. Journal of cognitive neuroscience. vol 22. issue 10. 2010-09-22. PMID:19925205. |
the brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity, which underlies learning and memory. |
2010-09-22 |
2023-08-12 |
human |
Marie-Christine Pardo. Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders. Vitamins and hormones. vol 82. 2010-08-20. PMID:20472139. |
extensive work implicates bdnf in hippocampus-dependent forms of learning and memory, although it also regulates other cognitive processes. |
2010-08-20 |
2023-08-12 |
Not clear |
Omar F Khabour, Karem H Alzoubi, Mahmoud A Alomari, Mohammad A Alzub. Changes in spatial memory and BDNF expression to concurrent dietary restriction and voluntary exercise. Hippocampus. vol 20. issue 5. 2010-08-10. PMID:19530223. |
spatial learning and memory formation was assessed using the radial arm water maze (rawm) paradigm, while bdnf protein was measured using elisa test. |
2010-08-10 |
2023-08-12 |
rat |
Yu-juan Li, Shu-ling Peng, Chao-quan Wan, Lin Cao, Yan-ping L. [Chronic pain impairs spatial learning and memory ability and down-regulates Bcl-2 and BDNF mRNA expression in hippocampus of neonatal rats]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 43. issue 6. 2010-07-15. PMID:16053732. |
[chronic pain impairs spatial learning and memory ability and down-regulates bcl-2 and bdnf mrna expression in hippocampus of neonatal rats]. |
2010-07-15 |
2023-08-12 |
rat |
Bente K Pedersen, Maria Pedersen, Karen S Krabbe, Helle Bruunsgaard, Vance B Matthews, Mark A Febbrai. Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals. Experimental physiology. vol 94. issue 12. 2010-01-18. PMID:19748969. |
brain-derived neurotrophic factor (bdnf) has been shown to regulate neuronal development and plasticity and plays a role in learning and memory. |
2010-01-18 |
2023-08-12 |
Not clear |
Phu V Tran, Stephanie J B Fretham, Erik S Carlson, Michael K Georgief. Long-term reduction of hippocampal brain-derived neurotrophic factor activity after fetal-neonatal iron deficiency in adult rats. Pediatric research. vol 65. issue 5. 2009-09-24. PMID:19190544. |
because bdnf modulates learning and memory, we assessed its expression in 65-d-old formerly iron deficient (fid) male rats that had been iron deficient during the fetal-neonatal period and treated with iron since postnatal day 7. |
2009-09-24 |
2023-08-12 |
rat |
A Giralt, T Rodrigo, E D Martín, J R Gonzalez, M Milà, V Ceña, M Dierssen, J M Canals, J Alberc. Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19121372. |
therefore, these results show that bdnf modulates the learning and memory alterations induced by mutant huntingtin. |
2009-05-20 |
2023-08-12 |
mouse |
Michelle Ploughman, Victoria Windle, Crystal L MacLellan, Nicole White, Jules J Doré, Dale Corbet. Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats. Stroke. vol 40. issue 4. 2009-04-24. PMID:19164786. |
brain-derived neurotrophic factor (bdnf) is involved in neuronal survival, synaptic plasticity, learning and memory, and neuroplasticity. |
2009-04-24 |
2023-08-12 |
rat |
Joseph C Madara, Eric S Levin. Presynaptic and postsynaptic NMDA receptors mediate distinct effects of brain-derived neurotrophic factor on synaptic transmission. Journal of neurophysiology. vol 100. issue 6. 2009-04-23. PMID:18922945. |
these effects may underlie a role for bdnf in learning and memory as well as developmental plasticity. |
2009-04-23 |
2023-08-12 |
Not clear |
Andrea Gómez-Palacio-Schjetnan, Martha L Escoba. In vivo BDNF modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers. Neuroscience letters. vol 445. issue 1. 2009-04-14. PMID:18782600. |
brain-derived neurotrophic factor (bdnf) has been proposed as a key regulator and mediator of long-term synaptic modifications related to learning and memory maintenance. |
2009-04-14 |
2023-08-12 |
rat |
Alan H Nagahara, David A Merrill, Giovanni Coppola, Shingo Tsukada, Brock E Schroeder, Gideon M Shaked, Ling Wang, Armin Blesch, Albert Kim, James M Conner, Edward Rockenstein, Moses V Chao, Edward H Koo, Daniel Geschwind, Eliezer Masliah, Andrea A Chiba, Mark H Tuszynsk. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nature medicine. vol 15. issue 3. 2009-03-30. PMID:19198615. |
in amyloid-transgenic mice, bdnf gene delivery, when administered after disease onset, reverses synapse loss, partially normalizes aberrant gene expression, improves cell signaling and restores learning and memory. |
2009-03-30 |
2023-08-12 |
mouse |
Carla Cunha, Andrea Angelucci, Angela D'Antoni, Mate D Dobrossy, Stephen B Dunnett, Nicoletta Berardi, Riccardo Brambill. Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments. Neurobiology of disease. vol 33. issue 3. 2009-03-10. PMID:19095063. |
brain-derived neurotrophic factor (bdnf) overexpression in the forebrain results in learning and memory impairments. |
2009-03-10 |
2023-08-12 |
mouse |
Carla Cunha, Andrea Angelucci, Angela D'Antoni, Mate D Dobrossy, Stephen B Dunnett, Nicoletta Berardi, Riccardo Brambill. Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments. Neurobiology of disease. vol 33. issue 3. 2009-03-10. PMID:19095063. |
this observation suggests that a widespread increase in bdnf in forebrain networks may result in adverse effects on learning and memory formation. |
2009-03-10 |
2023-08-12 |
mouse |
Shun-Wei Zhu, Alina Codita, Nenad Bogdanovic, Jens Hjerling-Leffler, Patrik Ernfors, Bengt Winblad, David W Dickins, Abdul H Mohamme. Influence of environmental manipulation on exploratory behaviour in male BDNF knockout mice. Behavioural brain research. vol 197. issue 2. 2009-02-23. PMID:18951926. |
it is widely accepted that brain derived neurotrophic factor (bdnf) plays a crucial role in mediating changes in learning and memory performance induced by environmental conditions. |
2009-02-23 |
2023-08-12 |
mouse |