| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsuyoshi Ando, Norio Takagi, Keiko Takagi, Tomoyuki Kago, Satoshi Take. Effects of nefiracetam on the levels of brain-derived neurotrophic factor and synapsin I mRNA and protein in the hippocampus of microsphere-embolized rats. European journal of pharmacology. vol 507. issue 1-3. 2005-07-25. PMID:15659294. |
these results suggest that enhancement of bdnf and synapsin i expression by nefiracetam treatment may be, at least in part, due to the improvement in the creb binding activity, contributing to the prevention of learning and memory dysfunction after sustained cerebral ischemia. |
2005-07-25 |
2023-08-12 |
rat |
| Kerrie Thomas, Alun Davie. Neurotrophins: a ticket to ride for BDNF. Current biology : CB. vol 15. issue 7. 2005-07-12. PMID:15823529. |
the secretion of bdnf from neurons is under activity-dependent control: this is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. |
2005-07-12 |
2023-08-12 |
Not clear |
| Elena Butovsky, Ana Juknat, Igor Goncharov, Judith Elbaz, Raya Eilam, Abraham Zangen, Zvi Voge. In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857384. |
moreover, bdnf is known to modulate synaptic plasticity and adaptive processes underlying learning and memory, leading to long-term functional and structural modification of synaptic connections. |
2005-07-05 |
2023-08-12 |
rat |
| F Gomez-Pinilla, S Vaynma. A "deficient environment" in prenatal life may compromise systems important for cognitive function by affecting BDNF in the hippocampus. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755541. |
the important role that the bdnf system plays in neural modeling and learning and memory processes suggests that fetal exposure to unfavorable intrauterine conditions may compromise proper cognitive function in adult life. |
2005-05-16 |
2023-08-12 |
Not clear |
| Isabel G Newton, M Elizabeth Forbes, Claudine Legault, James E Johnson, Judy K Brunso-Bechtold, David R Riddl. Caloric restriction does not reverse aging-related changes in hippocampal BDNF. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708443. |
we tested the hypotheses that aging is associated with a decline in hippocampal brain-derived neurotrophic factor (bdnf), a growth factor that enhances learning and memory, and that cr increases hippocampal bdnf. |
2005-05-09 |
2023-08-12 |
rat |
| Daniel T Radecki, Laurie M Brown, James Martinez, Timothy J Teyle. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476265. |
bdnf protects against stress-induced impairments in spatial learning and memory and ltp. |
2005-04-28 |
2023-08-12 |
human |
| Daniel T Radecki, Laurie M Brown, James Martinez, Timothy J Teyle. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476265. |
the present study investigated whether infusion of brain-derived neurotrophic factor (bdnf) could ameliorate stress-induced impairments in spatial learning and memory as well as hippocampal long-term potentiation (ltp) of rats. |
2005-04-28 |
2023-08-12 |
human |
| Daniel T Radecki, Laurie M Brown, James Martinez, Timothy J Teyle. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476265. |
these results demonstrate that spatial learning and memory, and ltp, a candidate neural substrate of learning and memory, are compromised during chronic stress, and may be protected by bdnf administration. |
2005-04-28 |
2023-08-12 |
human |
| J Matthew Kittelberger, Richard Moone. Acute injections of brain-derived neurotrophic factor in a vocal premotor nucleus reversibly disrupt adult birdsong stability and trigger syllable deletion. Journal of neurobiology. vol 62. issue 4. 2005-04-28. PMID:15547937. |
in other systems, neurotrophins, and brain-derived neurotrophic factor (bdnf) in particular, can mediate various forms of neural plasticity, including sensitive period neural circuit plasticity and activity-dependent synapse formation, and may also influence learning and memory. |
2005-04-28 |
2023-08-12 |
Not clear |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin. Ageing research reviews. vol 3. issue 4. 2005-04-12. PMID:15541711. |
at the molecular level, bdnf, serotonin and igfs can all stimulate the production of proteins involved in cellular stress adaptation, growth and repair, neurogenesis, learning and memory and cell survival. |
2005-04-12 |
2023-08-12 |
Not clear |
| Kuo Wu, Guo-Wei Len, Geoff McAuliffe, Chia Ma, Jessica P Tai, Fei Xu, Ira B Blac. Brain-derived neurotrophic factor acutely enhances tyrosine phosphorylation of the AMPA receptor subunit GluR1 via NMDA receptor-dependent mechanisms. Brain research. Molecular brain research. vol 130. issue 1-2. 2005-03-30. PMID:15519688. |
brain-derived growth factor (bdnf) acutely regulates synaptic transmission and modulates hippocampal long-term potentiation (ltp) and long-term depression (ltd), cellular models of plasticity associated with learning and memory. |
2005-03-30 |
2023-08-12 |
Not clear |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 6. 2005-03-15. PMID:15537738. |
brain-derived neurotrophic factor (bdnf) has been implicated as a molecular mediator of learning and memory. |
2005-03-15 |
2023-08-12 |
Not clear |
| Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinill. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548201. |
the finding that exercise increased brain-derived neurotrophic factor (bdnf), a molecule important for synaptic plasticity and learning and memory, impelled us to examine whether a bdnf-mediated mechanism subserves the capacity of exercise to improve hippocampal-dependent learning. |
2005-03-01 |
2023-08-12 |
Not clear |
| Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinill. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548201. |
these findings suggest a functional role for creb under the control of bdnf in mediating the exercise-induced enhancement in learning and memory. |
2005-03-01 |
2023-08-12 |
Not clear |
| John E Kolb, Joseph Trettel, Eric S Levin. BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol. Synapse (New York, N.Y.). vol 55. issue 1. 2005-02-17. PMID:15515007. |
these results provide a potential mechanism for the proposed role for bdnf in activity-dependent synaptic plasticity and, potentially, learning and memory processes. |
2005-02-17 |
2023-08-12 |
Not clear |
| Kiyofumi Yamada, Toshitaka Nabeshim. Interaction of BDNF/TrkB signaling with NMDA receptor in learning and memory. Drug news & perspectives. vol 17. issue 7. 2005-01-12. PMID:15514702. |
brain-derived neurotrophic factor (bdnf) and its receptor trkb play important roles in learning and memory. |
2005-01-12 |
2023-08-12 |
human |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
furthermore, bdnf protein levels are increased in app+/ps1+ and 2'-nh2-mptp-treated mice, possibly as a compensatory response to serotonergic and noradrenergic neurodegeneration in a brain region important for learning and memory. |
2004-09-24 |
2023-08-12 |
mouse |
| Lisa M Rattiner, Michael Davis, Christopher T French, Kerry J Ressle. Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 20. 2004-09-10. PMID:15152040. |
brain-derived neurotrophic factor (bdnf) and its receptor, tyrosine kinase receptor b (trkb), play a critical role in activity-dependent synaptic plasticity and have been implicated as mediators of hippocampal-dependent learning and memory. |
2004-09-10 |
2023-08-12 |
Not clear |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078544. |
it is known that bdnf facilitates the synapse by modulating synapsin i and creb, which have been implicated in synaptic plasticity associated to learning and memory. |
2004-05-24 |
2023-08-12 |
rat |
| R Molteni, A Wu, S Vaynman, Z Ying, R J Barnard, F Gómez-Pinill. Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience. vol 123. issue 2. 2004-05-12. PMID:14698750. |
exercise reversed the decrease in bdnf and its downstream effectors on plasticity such as synapsin i, a molecule with a key role in the modulation of neurotransmitter release by bdnf, and the transcription factor cyclic amp response element binding protein (creb), important for learning and memory. |
2004-05-12 |
2023-08-12 |
Not clear |