| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miao-Kun Sun, Daniel L Alko. Effects of 4-methylcatechol on spatial memory and depression. Neuroreport. vol 19. issue 3. 2008-04-09. PMID:18303581. |
4-methylcatechol (4-mc), a stimulator of brain-derived neurotrophic factor (bdnf) expression and an indirect pkc activator significantly enhanced spatial learning and memory in rats and produced an antidepressant effect. |
2008-04-09 |
2023-08-12 |
rat |
| K Schindowski, K Belarbi, L Bué. Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes, brain, and behavior. vol 7 Suppl 1. 2008-03-12. PMID:18184369. |
in particular, brain-derived neurotrophic factor (bdnf) plays a crucial role in cognition, learning and memory formation by modulating synaptic plasticity and is, therefore, a critical molecule in dementia and neurodegenerative diseases. |
2008-03-12 |
2023-08-12 |
Not clear |
| Etsuko Maruyama, Kenji Ogawa, Shogo Endo, Masafumi Tsujimoto, Tsutomu Hashikawa, Takuji Nabetani, Akira Tsugit. Brain-derived neurotrophic factor induces cell surface expression of short-form tenascin R complex in hippocampal postsynapses. The international journal of biochemistry & cell biology. vol 39. issue 10. 2008-01-08. PMID:17618159. |
brain-derived neurotrophic factor (bdnf) is involved in hippocampal functions such as learning and memory and it plays a crucial role in regulating synaptic plasticity. |
2008-01-08 |
2023-08-12 |
mouse |
| Undine E Lang, Rainer Hellweg, Frank Seifert, Florian Schubert, Juergen Gallina. Correlation between serum brain-derived neurotrophic factor level and an in vivo marker of cortical integrity. Biological psychiatry. vol 62. issue 5. 2007-10-26. PMID:17560556. |
brain-derived neurotrophic factor (bdnf) signaling at synapses improves synaptic strengthening associated with learning and memory. |
2007-10-26 |
2023-08-12 |
Not clear |
| A M Marini, X Jiang, X Wu, H Pan, Z Guo, M P Mattson, N Blondeau, A Novelli, R H Lipsk. Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli. Amino acids. vol 32. issue 3. 2007-09-14. PMID:16998712. |
in this article, we describe stress-induced neuroprotective mechanisms highlighting the role of brain-derived neurotrophic factor (bdnf), a protein that plays a crucial role in neuronal survival and maintenance, neurogenesis and learning and memory. |
2007-09-14 |
2023-08-12 |
Not clear |
| Xiao-Heng Li, Neng-Bao Liu, Min-Hai Zhang, Yan-Ling Zhou, Jia-Wan Liao, Xiang-Qian Liu, Hong-Wei Che. Effects of chronic multiple stress on learning and memory and the expression of Fyn, BDNF, TrkB in the hippocampus of rats. Chinese medical journal. vol 120. issue 8. 2007-07-12. PMID:17517182. |
effects of chronic multiple stress on learning and memory and the expression of fyn, bdnf, trkb in the hippocampus of rats. |
2007-07-12 |
2023-08-12 |
rat |
| Xiao-Heng Li, Neng-Bao Liu, Min-Hai Zhang, Yan-Ling Zhou, Jia-Wan Liao, Xiang-Qian Liu, Hong-Wei Che. Effects of chronic multiple stress on learning and memory and the expression of Fyn, BDNF, TrkB in the hippocampus of rats. Chinese medical journal. vol 120. issue 8. 2007-07-12. PMID:17517182. |
the aim of this study was to investigate the effects of chronic multiple stress on spatial learning and memory as well as the expression of fyn, bdnf and trkb in the hippocampus of rats. |
2007-07-12 |
2023-08-12 |
rat |
| Ling Wang, Ruo-Jun X. The effects of perinatal protein malnutrition on spatial learning and memory behaviour and brain-derived neurotrophic factor concentration in the brain tissue in young rats. Asia Pacific journal of clinical nutrition. vol 16 Suppl 1. 2007-06-14. PMID:17392152. |
this study aimed to investigate the effects of perinatal protein malnutrition on brain derived-neurotrophic factor (bdnf) concentration in brain tissue and spatial learning and memory performance in young rats. |
2007-06-14 |
2023-08-12 |
rat |
| S Vaynman, Z Ying, F Gomez-Pinill. The select action of hippocampal calcium calmodulin protein kinase II in mediating exercise-enhanced cognitive function. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17161914. |
inhibiting camkii also blocked the exercise-induced upregulation of molecules critical for learning and memory, brain-derived neurotrophic factor (bdnf) and the transcription activator camp response-element-binding protein, which is regulated by and downstream to bdnf action. |
2007-04-11 |
2023-08-12 |
rat |
| In Koo Hwang, Ki-Yeon Yoo, Boo-Kyoung Jung, Jun Hwi Cho, Do-Hoon Kim, Tae-Cheon Kang, Young-Guen Kwon, Yong-Sun Kim, Moo Ho Wo. Correlations between neuronal loss, decrease of memory, and decrease expression of brain-derived neurotrophic factor in the gerbil hippocampus during normal aging. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16678162. |
it is known that the hippocampus has vital functions in learning and memory, behavioral regulation, and activity-dependent synaptic plasticity, and that the hippocampus contains high levels of brain-derived neurotrophic factor (bdnf). |
2006-11-14 |
2023-08-12 |
Not clear |
| Argel Aguilar-Valles, Edith Sánchez, Patricia de Gortari, Israela Balderas, Víctor Ramírez-Amaya, Federico Bermúdez-Rattoni, Patricia Joseph-Brav. Analysis of the stress response in rats trained in the water-maze: differential expression of corticotropin-releasing hormone, CRH-R1, glucocorticoid receptors and brain-derived neurotrophic factor in limbic regions. Neuroendocrinology. vol 82. issue 5-6. 2006-07-18. PMID:16721035. |
mrna levels of brain-derived neurotrophic factor (bdnf) were also quantified due to its prominent role in learning and memory processes. |
2006-07-18 |
2023-08-12 |
rat |
| Beth A Luellen, Matthew E Szapacs, Christopher K Materese, Anne M Andrew. The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF. Neuropharmacology. vol 50. issue 3. 2006-05-24. PMID:16288930. |
moreover, damage to the hippocampus, a brain region important for learning and memory, and the modulation of anxiety and stress responsiveness, results in a transitory increase in bdnf. |
2006-05-24 |
2023-08-12 |
mouse |
| Dean-Chuan Wang, Shun-Sheng Chen, Yi-Ching Lee, Tsan-Ju Che. Amyloid-beta at sublethal level impairs BDNF-induced arc expression in cortical neurons. Neuroscience letters. vol 398. issue 1-2. 2006-05-10. PMID:16412575. |
one member of neurotrophins, brain-derived neurotrophic factor (bdnf), is known to be involved in the hippocampal long-term potentiation (ltp), a cellular model for learning and memory. |
2006-05-10 |
2023-08-12 |
rat |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
brain derived neurotrophic factor (bdnf) exhibits a sequence of actions on neurons ranging from acute enhancement of transmission to long-term promotion of neurite outgrowth and synaptogenesis associated with learning and memory. |
2006-04-28 |
2023-08-12 |
Not clear |
| Boldizsár Czéh, Mária Simo. [Neuroplasticity and depression]. Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata. vol 20. issue 1. 2006-02-23. PMID:16389729. |
camp-creb cascade, bdnf) have also been identified as important mediators of learning and memory. |
2006-02-23 |
2023-08-12 |
Not clear |
| Bharathi Hattiangady, Muddanna S Rao, Geetha A Shetty, Ashok K Shett. Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus. Experimental neurology. vol 195. issue 2. 2005-11-21. PMID:16002067. |
dramatically diminished creb phosphorylation (and persistently reduced levels of bdnf and npy) at old age may underlie the learning and memory impairments observed during senescence. |
2005-11-21 |
2023-08-12 |
rat |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Brain-derived neurotrophic factor in amygdala-dependent learning. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061519. |
the neurotrophin brain-derived neurotrophic factor (bdnf) has recently emerged as a possible molecular mediator of activity-dependent synaptic plasticity underlying learning and memory. |
2005-10-19 |
2023-08-12 |
Not clear |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Brain-derived neurotrophic factor in amygdala-dependent learning. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061519. |
long-term potentiation (ltp) within the hippocampus and hippocampally dependent behaviors has been the primary model for examining the role of bdnf in learning and memory. |
2005-10-19 |
2023-08-12 |
Not clear |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Brain-derived neurotrophic factor in amygdala-dependent learning. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061519. |
this article reviews the different levels of research on bdnf in learning and memory. |
2005-10-19 |
2023-08-12 |
Not clear |
| Sophie Pezet, Marzia Malcangi. Brain-derived neurotrophic factor as a drug target for CNS disorders. Expert opinion on therapeutic targets. vol 8. issue 5. 2005-08-22. PMID:15469390. |
in adulthood, bdnf can modulate neuronal synaptic strength and has been implicated in hippocampal mechanisms of learning and memory and spinal mechanisms for pain. |
2005-08-22 |
2023-08-12 |
Not clear |