| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Mogi, T Yonezawa, D-S Chen, J-Y Li, T Sawasaki, M Nishihar. Correlation between spontaneous feeding behavior and neuropeptide Y profile in the third ventricular cerebrospinal fluid of goats. Domestic animal endocrinology. vol 25. issue 2. 2003-10-29. PMID:12972374. |
feeding behavior is regulated by neural signals in the hypothalamus, but secretory activities of these signals in vivo and their relationship with spontaneous feeding remain to be solved. |
2003-10-29 |
2023-08-12 |
Not clear |
| M Kinoshita, R Moriyama, H Tsukamura, K-I Maed. A rat model for the energetic regulation of gonadotropin secretion: role of the glucose-sensing mechanism in the brain. Domestic animal endocrinology. vol 25. issue 1. 2003-10-27. PMID:12963104. |
from those experiments, the information on energy deficiency is considered to be detected by specific central sensors and conveyed to the hypothalamus to regulate lh release as well as food intake. |
2003-10-27 |
2023-08-12 |
rat |
| Siok L Dun, G Cristina Brailoiu, Jun Yang, Jaw Kang Chang, Nae J Du. Neuropeptide W-immunoreactivity in the hypothalamus and pituitary of the rat. Neuroscience letters. vol 349. issue 2. 2003-10-23. PMID:12946555. |
the pattern of distribution of irnpw in the hypothalamus corroborates a possible role of npw on prolactin release and feeding behavior reported by others. |
2003-10-23 |
2023-08-12 |
rat |
| Jun Zhou, David S Roane, Xiaochun Xi, Iwona Bogacka, Bing Li, Donna H Ryan, Roy J Marti. Short-term food restriction and refeeding alter expression of genes likely involved in brain glucosensing. Experimental biology and medicine (Maywood, N.J.). vol 228. issue 8. 2003-10-23. PMID:12968066. |
the results indicate that putative glucosensing (gk, glut-2, and glp-1r) gene expression in the hypothalamus and brainstem is reduced in response to food intake, depending on prior nutritional status. |
2003-10-23 |
2023-08-12 |
rat |
| Prabal K Guha, Daniel Villarreal, Garry P Reams, Ronald H Freema. Role of leptin in the regulation of body fluid volume and pressures. American journal of therapeutics. vol 10. issue 3. 2003-10-10. PMID:12756428. |
it regulates energy balance by binding to receptors in the hypothalamus, leading to alterations in food intake, temperature, and energy expenditure. |
2003-10-10 |
2023-08-12 |
Not clear |
| Helga Davidowa, Yuzhen Li, Andreas Plageman. Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats. The European journal of neuroscience. vol 18. issue 3. 2003-10-03. PMID:12911757. |
food intake and energy expenditure are regulated by neuropeptides in the hypothalamus. |
2003-10-03 |
2023-08-12 |
rat |
| Min-Seon Kim, Cho-Ya Yoon, Kyeong-Han Park, Chan-Soo Shin, Kyong-Soo Park, Seong-Yeon Kim, Bo-Youn Cho, Hong-Kyu Le. Changes in ghrelin and ghrelin receptor expression according to feeding status. Neuroreport. vol 14. issue 10. 2003-09-26. PMID:12876464. |
this study was undertaken to investigate changes in expression levels of stomach ghrelin as well as of ghrelin receptor in the hypothalamus and pituitary glands according to feeding state. |
2003-09-26 |
2023-08-12 |
rat |
| Rachel L Batterham, Mark A Cohen, Sandra M Ellis, Carel W Le Roux, Dominic J Withers, Gary S Frost, Mohammad A Ghatei, Stephen R Bloo. Inhibition of food intake in obese subjects by peptide YY3-36. The New England journal of medicine. vol 349. issue 10. 2003-09-17. PMID:12954742. |
in common with the adipocyte hormone leptin, pyy reduces food intake by modulating appetite circuits in the hypothalamus. |
2003-09-17 |
2023-08-12 |
human |
| Rekha Pal, Abhiram Sah. Leptin signaling in the hypothalamus during chronic central leptin infusion. Endocrinology. vol 144. issue 9. 2003-09-16. PMID:12933650. |
we propose that an alteration in leptin signaling in the hypothalamus through pathways other than stat3 and/or a defect in downstream of stat3 signaling may be involved in food intake recovery seen after an initial decrease during chronic central leptin infusion. |
2003-09-16 |
2023-08-12 |
rat |
| Caroline R Abbott, Adam R Kennedy, Alison M Wren, Michela Rossi, Kevin G Murphy, Leighton J Seal, Jeannie F Todd, Mohammad A Ghatei, Caroline J Small, Stephen R Bloo. Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology. vol 144. issue 9. 2003-09-16. PMID:12933668. |
no significant alteration in feeding was observed following injection into the supraoptic nucleus, lateral hypothalamic area, medial preoptic area, anterior hypothalamic area, or ventromedial nucleus of the hypothalamus. |
2003-09-16 |
2023-08-12 |
rat |
| Caroline R Abbott, Adam R Kennedy, Alison M Wren, Michela Rossi, Kevin G Murphy, Leighton J Seal, Jeannie F Todd, Mohammad A Ghatei, Caroline J Small, Stephen R Bloo. Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology. vol 144. issue 9. 2003-09-16. PMID:12933668. |
these studies suggest that the orexigenic effect of mch may be mediated via activation or inhibition of these feeding circuits within the arcuate nucleus and paraventricular nucleus of the hypothalamus. |
2003-09-16 |
2023-08-12 |
rat |
| F Lanfranco, L Gianotti, S Destefanis, E Arvat, E Ghigo, F Camann. [Endocrine abnormalities in anorexia nervosa]. Minerva endocrinologica. vol 28. issue 2. 2003-09-15. PMID:12717347. |
in fact, several evidences suggest the existence in an of hypothalamus functional alterations, which may be involved in the development and maintenance of the food intake disorder; on the other hand, the increased crh secretion seems to be secondary to malnutrition as well as gh hypersecretion coupled to low igf-i levels; the latter is a common finding in an, as well as in other undernutrition and malabsorption conditions, type 1 diabetes mellitus, liver cirrhosis and catabolic states. |
2003-09-15 |
2023-08-12 |
Not clear |
| Gang Li, Charles V Mobbs, Philip J Scarpac. Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes. vol 52. issue 8. 2003-09-15. PMID:12882910. |
this study demonstrates that targeted pomc gene delivery in the hypothalamus suppresses food intake and weight gain and reduces visceral adiposity and hyperinsulinemia in leptin-resistant obese zucker rats. |
2003-09-15 |
2023-08-12 |
rat |
| Prashant Trivedi, Michael Jiang, Constantin C Tamvakopoulos, Xiaolan Shen, Hong Yu, Steven Mock, Judy Fenyk-Melody, Lex H T Van der Ploeg, Xiao-Ming Gua. Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats. Brain research. vol 977. issue 2. 2003-09-02. PMID:12834882. |
we next surveyed by in vitro autoradiographic studies the distribution of selective (125)i-mt-ii binding sites in multiple brain regions including areas important for feeding regulation such as the hypothalamus and caudal brainstem. |
2003-09-02 |
2023-08-12 |
rat |
| Richard G Hunter, Michael J Kuha. CART peptides as targets for CNS drug development. Current drug targets. CNS and neurological disorders. vol 2. issue 3. 2003-08-27. PMID:12769800. |
the presence of cart immunoreactivity in specific nuclei of the hypothalamus has led to an examination of icv-injected cart peptides effects on feeding, which have proven to be significantly anorectic. |
2003-08-27 |
2023-08-12 |
human |
| J Iqbal, B A Henry, S Pompolo, A Rao, I J Clark. Long-term alteration in bodyweight and food restriction does not affect the gene expression of either preproorexin or prodynorphin in the sheep. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676151. |
we have employed in situ hybridization to examine the effects of long-term alterations in the bodyweight on expression of mrna for preproorexin and prodynorphin in the putative feeding centers of the ovine hypothalamus. |
2003-08-13 |
2023-08-12 |
rat |
| Norimasa Sagawa, Shigeo Yura, Hiroaki Itoh, Kazuyo Kakui, Maki Takemura, Mercy A Nuamah, Yoshihiro Ogawa, Hiroaki Masuzaki, Kazuwa Nakao, Shingo Fuji. Possible role of placental leptin in pregnancy: a review. Endocrine. vol 19. issue 1. 2003-07-29. PMID:12583603. |
leptin was initially identified as an adipocyte-derived hormone that decreases food intake and body weight via its receptor in the hypothalamus. |
2003-07-29 |
2023-08-12 |
Not clear |
| Carolyn A Steward, Tracey L Horan, Sandrine Schuhler, Geoffrey W Bennett, Francis J P Eblin. Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster. Neuroreport. vol 14. issue 5. 2003-07-23. PMID:12692464. |
trh-gly (5 microg) produced a small decrease in food intake (p < 0.05), lasting for 6 h. we conclude that trh and trh analogues possess anorexigenic capacities in this species, with a likely site of action in the hypothalamus. |
2003-07-23 |
2023-08-12 |
rat |
| Eitan Gur, Michael E Newman, Yosefa Avraham, Eliyahu Dremencov, Elliot M Berr. The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats. Nutritional neuroscience. vol 6. issue 3. 2003-07-18. PMID:12793521. |
the fact that such differential effects on 5-ht release appeared only in the hypothalamus, the center of regulation of energy balance, suggests a compensatory role in fr by increasing 5-ht secretion, thereby reducing feeding behavior. |
2003-07-18 |
2023-08-12 |
rat |
| LuGuang Luo, David B MacLea. Effects of thyroid hormone on food intake, hypothalamic Na/K ATPase activity and ATP content. Brain research. vol 973. issue 2. 2003-07-16. PMID:12738067. |
in order to address this question, we tested the effects of t3 on food intake and body weight in rats and measured neuronal na/k atpase activity and atp content in the hypothalamus. |
2003-07-16 |
2023-08-12 |
rat |