| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Noordmans, D K Song, C J Noordmans, M Garrity-Moses, M J During, H L Fitzsimons, M J Imperiale, N M Bouli. Adeno-associated viral glutamate decarboxylase expression in the lateral nucleus of the rat hypothalamus reduces feeding behavior. Gene therapy. vol 11. issue 9. 2004-06-28. PMID:14961066. |
these findings suggest that increased gaba production in lateral nucleus of the hypothalamus induced by gad65 gene transfer may reduce weight gain through reduced feeding. |
2004-06-28 |
2023-08-12 |
rat |
| Abhiram Sah. Minireview: A hypothalamic role in energy balance with special emphasis on leptin. Endocrinology. vol 145. issue 6. 2004-06-24. PMID:15044360. |
proper signaling in the hypothalamus by leptin, a long-sought peripheral factor that relays the status of fat stores, is critical to normal regulation of food intake and body weight. |
2004-06-24 |
2023-08-12 |
Not clear |
| Ai-Jun Li, Sue Ritte. Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus. The European journal of neuroscience. vol 19. issue 8. 2004-06-18. PMID:15090041. |
while the specific roles of these distinct sources of innervation are not known, npy neurotransmission within the hypothalamus appears to contribute to glucoregulatory feeding. |
2004-06-18 |
2023-08-12 |
rat |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
semi-quantitative reverse transcription-polymerase chain reaction analyses showed that crf and npy mrna fluctuated with food intake in the brain region containing the mid-posterior hypothalamus, pretectum, and optic tectum: crf mrna decreased 6 h after a meal and remained low through 31 days of food deprivation; npy mrna content also decreased 6 h after a meal, but increased to prefeeding levels by 24 h. plasma corticosterone concentration increased 6 h after a meal, returned to prefeeding levels by 24 h, and did not change with prolonged food deprivation. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| Si Ho Choi, Bum Sup Kwon, Seoul Lee, Thomas A Houpt, Hoon Taek Lee, Dong Goo Kim, Jeong Won Jahn. Systemic 5-hydroxy-L-tryptophan down-regulates the arcuate CART mRNA level in rats. Regulatory peptides. vol 115. issue 2. 2004-05-28. PMID:12972322. |
the 5-ht contents of the hypothalamus as well as the brainstem was increased persistently by 5-htp injections, and food intake and body weight gain reduced. |
2004-05-28 |
2023-08-12 |
rat |
| Sebastien G Bouret, Shin J Draper, Richard B Simerl. Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 11. 2004-05-28. PMID:15028773. |
formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. |
2004-05-28 |
2023-08-12 |
mouse |
| Sebastien G Bouret, Shin J Draper, Richard B Simerl. Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 11. 2004-05-28. PMID:15028773. |
we tested this possibility by using dii axonal labeling to examine the development of projections from the arh to other parts of the hypothalamus in neonatal mice, paying particular attention to the innervation of the paraventricular nucleus (pvh), the dorsomedial nucleus (dmh), and the lateral hypothalamic area (lha), each of which have been implicated in the regulation of feeding. |
2004-05-28 |
2023-08-12 |
mouse |
| Gertjan van Dijk, Jan H Strubb. Time-dependent effects of neuropeptide Y infusion in the paraventricular hypothalamus on ingestive and associated behaviors in rats. Physiology & behavior. vol 79. issue 4-5. 2004-05-19. PMID:12954397. |
in this study the role of neuropeptide y (npy) in the paraventricular nucleus of the hypothalamus (pvn) in the daily regulation of feeding, drinking, locomotor activity, and nestbox occupation was investigated. |
2004-05-19 |
2023-08-12 |
rat |
| Eun Sung Park, Seona Jo, Seong Joon Yi, Jin Sang Kim, Heungshik S Ee, In Se Lee, Kang Moon Seo, Je Kyung Sung, Inhyung Lee, Yeo Sung Yoo. Effect of capsaicin on cholecystokinin and neuropeptide Y expressions in the brain of high-fat diet fed rats. The Journal of veterinary medical science. vol 66. issue 2. 2004-05-19. PMID:15031536. |
it is concluded that (1) npy-ir may react more sensitively on capsaicin than cck-ir, (2) no rapid increase of body weight in capsaicin treated rats may result from the diminished food intake through the low expression of npy in hypothalamus in hf-cap group. |
2004-05-19 |
2023-08-12 |
rat |
| Suraj Unniappan, Luis Fabián Canosa, Richard E Pete. Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responses to central and peripheral injections. Neuroendocrinology. vol 79. issue 2. 2004-05-17. PMID:15004432. |
slot blot analysis revealed a significant postprandial decrease in preproghrelin mrna expression in the hypothalamus (1 and 3 h after feeding) and gut (3 h after feeding). |
2004-05-17 |
2023-08-12 |
human |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
the hypothalamus is a key regulator of food intake and energy balance, coordinating body adiposity and nutritional state in response to peripheral hormones, such as leptin, peptide yy-(3-36), and ghrelin. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
to date the hormonal regulation of ampk in the hypothalamus, or its potential role in the control of food intake, have not been reported. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
here we demonstrate that counter-regulatory hormones involved in appetite control regulate ampk activity and that pharmacological activation of ampk in the hypothalamus increases food intake. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
by contrast, injection of ghrelin in vivo, which increases food intake, stimulates ampk activity in the hypothalamus. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
consistent with the effect of ghrelin, injection of 5-amino-4-imidazole carboxamide riboside, a pharmacological activator of ampk, into either the third cerebral ventricle or directly into the paraventricular nucleus of the hypothalamus significantly increased food intake. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
these results suggest that ampk is regulated in the hypothalamus by hormones which regulate food intake. |
2004-05-07 |
2023-08-12 |
Not clear |
| Ulrika Andersson, Karin Filipsson, Caroline R Abbott, Angela Woods, Kirsty Smith, Stephen R Bloom, David Carling, Caroline J Smal. AMP-activated protein kinase plays a role in the control of food intake. The Journal of biological chemistry. vol 279. issue 13. 2004-05-07. PMID:14742438. |
furthermore, direct pharmacological activation of ampk in the hypothalamus is sufficient to increase food intake. |
2004-05-07 |
2023-08-12 |
Not clear |
| J M Mancilla-Díaz, R E Escartín-Pérez, V E López-Alons. The effects of 5-HT on feeding behaviour in mianserin- or cyproheptadine-pretreated rats. Eating and weight disorders : EWD. vol 8. issue 4. 2004-04-21. PMID:15018375. |
we examined the effects of 5-ht on the feeding behaviour patterns of rats pretreated with mianserin (5-ht(1b/2a/1d receptor antagonist) or cyproheptadine (a 5-ht(2c) receptor antagonist), injected into the pariventricular hypothalamus nucleus (pvn). |
2004-04-21 |
2023-08-12 |
rat |
| Hisayuki Funahashi, Shuori Yamada, Haruaki Kageyama, Fumiko Takenoya, Jian Lian Guan, Seiji Shiod. Co-existence of leptin- and orexin-receptors in feeding-regulating neurons in the hypothalamic arcuate nucleus-a triple labeling study. Peptides. vol 24. issue 5. 2004-04-20. PMID:12895654. |
the arcuate nucleus (arc) of the hypothalamus has been identified as a prime feeding regulating center in the brain. |
2004-04-20 |
2023-08-12 |
Not clear |
| S Asakuma, O Hiraku, Y Kurose, S Kobayashi, Y Terashim. Diurnal rhythm of cerebrospinal fluid and plasma leptin levels related to feeding in non-lactating and lactating rats. The Journal of endocrinology. vol 180. issue 2. 2004-04-16. PMID:14765980. |
leptin suppresses food intake and increases energy expenditure in the hypothalamus. |
2004-04-16 |
2023-08-12 |
rat |