| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frank Svec, Patrick Robinson, Leslie Michel, Jessica Bradley, Connie Corll, Johnny R Porte. Caloric intake and hypothalamic neurotransmitters in Zucker rats made acutely diabetic with streptozocin. Nutritional neuroscience. vol 7. issue 5-6. 2005-03-03. PMID:15682928. |
it is hypothesized that in the obese zucker rat decrements in food intake are mediated by increase in serotonin turnover in the hypothalamus and these changes are related to changes of insulin levels. |
2005-03-03 |
2023-08-12 |
rat |
| Izhar A Khan, Peter Thoma. Aroclor 1254 inhibits tryptophan hydroxylase activity in rat brain. Archives of toxicology. vol 78. issue 6. 2005-03-01. PMID:14997283. |
in two separate experiments, aroclor 1254 exposure consistently reduced tph activity in the brainstem (7.2 and 8.7%), frontal cortex (17.4 and 14.8%), and hypothalamus (10.7 and 9.4%) without altering the rats' food intake or growth. |
2005-03-01 |
2023-08-12 |
rat |
| Luigi Brunetti, Giustino Orlando, Lucia Recinella, Barbara Michelotto, Claudio Ferrante, Michele Vacc. Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus. European journal of pharmacology. vol 493. issue 1-3. 2005-02-28. PMID:15189762. |
adipose tissue hormones such as leptin have been shown to modulate neurotransmitters which control feeding in the hypothalamus. |
2005-02-28 |
2023-08-12 |
Not clear |
| Luigi Brunetti, Giustino Orlando, Lucia Recinella, Barbara Michelotto, Claudio Ferrante, Michele Vacc. Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus. European journal of pharmacology. vol 493. issue 1-3. 2005-02-28. PMID:15189762. |
we can conclude that, similarly to leptin, but differently from adiponectin, the adipose tissue hormone resistin could affect the central mechanisms of feeding by inhibiting catecholamine release in the hypothalamus. |
2005-02-28 |
2023-08-12 |
Not clear |
| Kichoon Lee, Bing Li, Xiaochun Xi, Yeunsu Suh, Roy J Marti. Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior. Endocrinology. vol 146. issue 1. 2005-01-18. PMID:15375032. |
nutrient sensing in the hypothalamus is tightly related to food intake regulation. |
2005-01-18 |
2023-08-12 |
Not clear |
| Yajun Tu, Jagan N Thupari, Eun-Kyoung Kim, Michael L Pinn, Timothy H Moran, Gabriele V Ronnett, Francis P Kuhajd. C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure. Endocrinology. vol 146. issue 1. 2005-01-18. PMID:15498887. |
analysis of the gene expression changes in hypothalamus demonstrated that the reduced food intake in c75-treated dio mice might be mediated by inhibition of orexigenic neuropeptide expression and induction of anorexigenic neuropeptide expression. |
2005-01-18 |
2023-08-12 |
mouse |
| N W Gilpin, R B Stewart, J M Murphy, N E Badia-Elde. Neuropeptide Y in the paraventricular nucleus of the hypothalamus increases ethanol intake in high- and low-alcohol-drinking rats. Alcoholism, clinical and experimental research. vol 28. issue 10. 2005-01-18. PMID:15597081. |
the behavioral effects of neuropeptide y (npy) attributed to its actions in the hypothalamus are complex and include effects on feeding, sedation, and the hypothalamic-pituitary-adrenal axis. |
2005-01-18 |
2023-08-12 |
rat |
| Q Nie, H Zeng, M Lei, N A Ishag, M Fang, B Sun, G Yang, X Zhan. Genomic organisation of the chicken ghrelin gene and its single nucleotide polymorphisms detected by denaturing high-performance liquid chromatography. British poultry science. vol 45. issue 5. 2005-01-18. PMID:15623213. |
(1) ghrelin is a novel endogenous ligand for the growth hormone secretagogue receptor (ghs-r) and is expressed primarily in the stomach and hypothalamus with the probable function of stimulating gh secretion and food intake both in mammals and poultry. |
2005-01-18 |
2023-08-12 |
mouse |
| Eiko Ueyama, Yoshihiro Morikawa, Tsuneo Yasuda, Emiko Senb. Attenuation of fasting-induced phosphorylation of mitogen-activated protein kinases (ERK/p38) in the mouse hypothalamus in response to refeeding. Neuroscience letters. vol 371. issue 1. 2005-01-03. PMID:15500963. |
thus, refeeding rapidly reduced the fasting-induced phosphorylation of erk, p38, and creb, suggesting that the activation of these signal molecules in the hypothalamus is precisely regulated with feeding status. |
2005-01-03 |
2023-08-12 |
mouse |
| Saeko Takano, Setsuko Kanai, Hiroko Hosoya, Minoru Ohta, Hiroshi Uematsu, Kyoko Miyasak. Orexin-A does not stimulate food intake in old rats. American journal of physiology. Gastrointestinal and liver physiology. vol 287. issue 6. 2004-12-20. PMID:15271651. |
the decrease in the ox1r protein level in the hypothalamus could be responsible for orexin-a's lack of stimulation of food intake in old rats. |
2004-12-20 |
2023-08-12 |
rat |
| An Viggiano, M Monda, Al Viggiano, F Fuccio, B De Luc. Extracellular GABA in the medial hypothalamus is increased following hypocretin-1 administration. Acta physiologica Scandinavica. vol 182. issue 1. 2004-12-20. PMID:15329061. |
as it is well known that the medial hypothalamus (mh) is involved in the feeding behaviour also through gabaergic circuits, the aim of this experiment was to investigate the effect of an hypocretin 1 intracerebroventricular (icv) injection on the extracellular levels of gaba in the mh. |
2004-12-20 |
2023-08-12 |
Not clear |
| Brent E Wisse, Kayoko Ogimoto, Gregory J Morton, Charles W Wilkinson, R Scott Frayo, David E Cummings, Michael W Schwart. Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis. American journal of physiology. Endocrinology and metabolism. vol 287. issue 6. 2004-12-16. PMID:15304373. |
interleukin-1beta (il-1beta) is synthesized in a variety of tissues, including the hypothalamus, where it is implicated in the control of food intake. |
2004-12-16 |
2023-08-12 |
human |
| Sumit Bhattacharyya, Jian'an Luan, I Sadaf Farooqi, Julia Keogh, Carl Montague, John Brennand, Lynn Jorde, Nicholas J Wareham, Stephen O'Rahill. Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor. The Journal of endocrinology. vol 183. issue 1. 2004-12-14. PMID:15525579. |
central administration of neuromedin u (nmu) suppresses food intake acting through the nmu-2 receptor (nmu2r), which is expressed in the hypothalamus. |
2004-12-14 |
2023-08-12 |
human |
| Milagros Rocha, Chen Bing, Gareth Williams, Marisa Puert. Physiologic estradiol levels enhance hypothalamic expression of the long form of the leptin receptor in intact rats. The Journal of nutritional biochemistry. vol 15. issue 6. 2004-12-06. PMID:15157938. |
we investigated whether the hypophagic effect of estradiol is mediated by stimulating pomc and/or inhibiting npy neuronal pathways in the hypothalamus, which respectively inhibit and stimulate feeding. |
2004-12-06 |
2023-08-12 |
rat |
| Wing May Kong, Niamh M Martin, Kirsty L Smith, James V Gardiner, Ian P Connoley, David A Stephens, Waljit S Dhillo, Mohammad A Ghatei, Caroline J Small, Stephen R Bloo. Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure. Endocrinology. vol 145. issue 11. 2004-11-30. PMID:15297436. |
however, here we show that the thyroid hormone t(3) directly stimulates feeding at the level of the hypothalamus. |
2004-11-30 |
2023-08-12 |
rat |
| Krisztina Hegyi, Kristóf A Fülöp, Krisztina J Kovács, András Falus, Sára Tót. High leptin level is accompanied with decreased long leptin receptor transcript in histamine deficient transgenic mice. Immunology letters. vol 92. issue 1-2. 2004-11-24. PMID:15081545. |
leptin is a multifunctional cytokine and hormone that primarily acts in the hypothalamus and plays a key role in regulation of food intake and energy expenditure. |
2004-11-24 |
2023-08-12 |
mouse |
| J L Soengas, M Aldegund. Brain glucose and insulin: effects on food intake and brain biogenic amines of rainbow trout. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 190. issue 8. 2004-11-15. PMID:15138792. |
the effects of central (intracerebroventricular, 9 microg fish(-1)) and peripheral (intraperitoneal, 4 mg kg(-1)) administration of bovine insulin, as well as the effect of hyperglycemia (oral administration of 1 g glucose fish(-1)) and brain glucodeprivation (intracerebroventricular administration of 2-deoxy-d-glucose) on food intake and levels of brain (telencephalon, preoptic area, and hypothalamus) biogenic amines (serotonin, dopamine, noradrenaline and their metabolites 5-hydroxyindoleacetic acid, and dihydroxyphenylacetic acid) were assessed on rainbow trout ( oncorhynchus mykiss). |
2004-11-15 |
2023-08-12 |
cattle |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
in the hypothalamus, insulin and leptin share a common signaling pathway involved in food intake, namely the insulin receptor substrate, phosphatidylinositol 3-kinase pathway. |
2004-11-03 |
2023-08-12 |
Not clear |
| Takayuki Masaki, Seiichi Chiba, Tohru Yasuda, Hitoshi Noguchi, Tetsuya Kakuma, Takeshi Watanabe, Toshiie Sakata, Hironobu Yoshimats. Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Diabetes. vol 53. issue 9. 2004-10-26. PMID:15331534. |
furthermore, central administration of a histamine h(1)-r agonist affected feeding behavior, body weight, and c-fos-like immunoreactivity in the hypothalamus. |
2004-10-26 |
2023-08-12 |
mouse |
| Hans-Rudolf Berthou. Mind versus metabolism in the control of food intake and energy balance. Physiology & behavior. vol 81. issue 5. 2004-10-18. PMID:15234184. |
while many projections from the hypothalamus contain the various "feeding peptides," the neurochemistry of projections to the hypothalamus has not been well characterized. |
2004-10-18 |
2023-08-12 |
Not clear |