| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Pedrazzini, F Pralong, E Grouzman. Neuropeptide Y: the universal soldier. Cellular and molecular life sciences : CMLS. vol 60. issue 2. 2003-04-30. PMID:12678499. |
in particular, npy is involved in the regulatory loops that control food intake in the hypothalamus and appears also to be important for regulating the activity of neuroendocrine axes under poor metabolic conditions. |
2003-04-30 |
2023-08-12 |
human |
| G Li, R L Klein, M Matheny, M A King, E M Meyer, P J Scarpac. Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats. Neuroscience. vol 115. issue 3. 2003-04-07. PMID:12435426. |
direct delivery of raav-il-6 into rat hypothalamus suppressed weight gain and visceral adiposity without affecting food intake over a 5-week period. |
2003-04-07 |
2023-08-12 |
rat |
| Tetsuro Shirasaka, Mayumi Takasaki, Hiroshi Kanna. Cardiovascular effects of leptin and orexins. American journal of physiology. Regulatory, integrative and comparative physiology. vol 284. issue 3. 2003-03-31. PMID:12571072. |
on the other hand, orexins (orexin-a and -b) or hypocretins (hypocretin-1 and -2) were recently discovered in the hypothalamus, in which a number of neuropeptides are known to stimulate or suppress food intake. |
2003-03-31 |
2023-08-12 |
mouse |
| A Cecilia Karlsson, Anna Karin Lindroos, Lauren Lissner, Jarl S Torgerson, Björn Carlsson, Lena M S Carlsson, Lars Sjöströ. Evidence for gender-specific associations between leptin and olfaction. The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia. vol 5. issue 6. 2003-03-28. PMID:12503223. |
the adipocyte-derived hormone leptin regulates food intake by stimulation of the long leptin receptor isoform in the hypothalamus. |
2003-03-28 |
2023-08-12 |
Not clear |
| A Laviano, M M Meguid, J R Gleason, F Rossi-Fanell. VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia. Nutritional neuroscience. vol 5. issue 6. 2003-03-13. PMID:12509074. |
food intake is mainly controlled in the hypothalamus via a series of functionally related nuclei, including the ventromedial nucleus of hypothalamus (vmn) and the lateral hypothalamic area (lha). |
2003-03-13 |
2023-08-12 |
rat |
| G S Fraley, T T Dinh, S Ritte. Immunotoxic catecholamine lesions attenuate 2DG-induced increase of AGRP mRNA. Peptides. vol 23. issue 6. 2003-03-04. PMID:12126736. |
injections of the immunotoxin, saporin conjugated to anti-dopamine-beta-hydroxylase (dsap), into the hypothalamic paraventricular nucleus (pvh) selectively destroy norepinephrine (ne) and epinephrine (e) terminals in the medial hypothalamus and abolish glucoprivic feeding. |
2003-03-04 |
2023-08-12 |
Not clear |
| Moshe Marikovsky, Charles I Rosenblum, Zehava Faltin, Miriam Friedman-Eina. Appearance of leptin in wound fluid as a response to injury. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 10. issue 5. 2003-03-04. PMID:12406166. |
the adiposity hormone leptin regulates food intake, body weight, reproduction and other metabolic and endocrine functions mainly through signaling to the hypothalamus. |
2003-03-04 |
2023-08-12 |
human |
| Z Y Huang, Z J Sun, S G Fa. [Obesity and the central nervous system regulation]. Sheng li ke xue jin zhan [Progress in physiology]. vol 32. issue 1. 2003-03-04. PMID:12545777. |
in the present review, the following contents are included: (1) satiety and its production, (2) adiposity signals and the regulation of food intake, (3) nuclei in central nervous system involved in food intake, (4) the first- and the second-order neuronal signaling in hypothalamus on control of food intake and (5) clinic implications. |
2003-03-04 |
2023-08-12 |
human |
| N Fujita, H Sakamaki, S Uotani, R Takahashi, H Kuwahara, A Kita, K Oshima, H Yamasaki, Y Yamaguchi, K Eguch. Acute effects of ethanol on feeding behavior and leptin-induced STAT3 phosphorylation in rat hypothalamus. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 27. issue 1. 2003-02-28. PMID:12532154. |
acute effects of ethanol on feeding behavior and leptin-induced stat3 phosphorylation in rat hypothalamus. |
2003-02-28 |
2023-08-12 |
rat |
| Christopher Bishop, Graham C Parker, Donald V Coscin. Nicotine and its withdrawal alter feeding induced by paraventricular hypothalamic injections of neuropeptide Y in Sprague-Dawley rats. Psychopharmacology. vol 162. issue 3. 2003-02-26. PMID:12122484. |
infusions of npy into the paraventricular nucleus of the hypothalamus (pvn), which normally produce robust feeding, were used to investigate changes in the pvn-npy system that may contribute to nic's effects on energy balance. |
2003-02-26 |
2023-08-12 |
rat |
| C Ruibal, J L Soengas, M Aldegund. Brain serotonin and the control of food intake in rainbow trout (Oncorhynchus mykiss): effects of changes in plasma glucose levels. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 188. issue 6. 2003-02-05. PMID:12122466. |
intraperitoneal treatment with bovine insulin (4 mg kg(-1)) decreased the 5-hydroxyindoleacetic acid/5-hydroxytryptamine ratio in hypothalamus after 1 h. intraperitoneal administration of fenfluramine (3 mg kg(-1)) caused a depression in food intake coincident with a significant decrease of the hypothalamic 5-hydroxyindoleacetic acid/5-hydroxytryptamine ratio. |
2003-02-05 |
2023-08-12 |
cattle |
| Valeria P Carlini, María E Monzón, Mariana M Varas, Andrea B Cragnolini, Helgi B Schiöth, Teresa N Scimonelli, Susana R de Bariogli. Ghrelin increases anxiety-like behavior and memory retention in rats. Biochemical and biophysical research communications. vol 299. issue 5. 2003-01-24. PMID:12470640. |
ghrelin is a peptide found in the hypothalamus and stomach that stimulates food intake and whose circulating concentrations are affected by nutritional state. |
2003-01-24 |
2023-08-12 |
rat |
| J P H Wildin. Neuropeptides and appetite control. Diabetic medicine : a journal of the British Diabetic Association. vol 19. issue 8. 2003-01-23. PMID:12147141. |
all these signals act at several central nervous system (cns) sites but the pathways converge on the hypothalamus, which contains a large number of peptide and other neurotransmitters that influence food intake. |
2003-01-23 |
2023-08-12 |
Not clear |
| G D Gamaro, L P Manoli, I L S Torres, R Silveira, C Dalma. Effects of chronic variate stress on feeding behavior and on monoamine levels in different rat brain structures. Neurochemistry international. vol 42. issue 2. 2003-01-21. PMID:12421590. |
the results suggest that emotional changes, such as exposure to stress situations can influence feeding behavior, chronic variate stress causes decreased ingestion of sweet food and decreased dopaminergic neurotransmission in hypothalamus. |
2003-01-21 |
2023-08-12 |
rat |
| Miguel López, Luisa Seoane, Sulay Tovar, Rosa M Señarís, Carlos Diégue. Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus. Neuroreport. vol 13. issue 14. 2003-01-15. PMID:12395121. |
these data indicate that the increments in food intake in hyperthyroidism could be mediated, at least in some extent, by a decreased expression, at the paraventricular nucleus of the hypothalamus, of the anorexigenic cocaine- and amphetamine-regulated transcript peptides. |
2003-01-15 |
2023-08-12 |
rat |
| Christian Bjørbaek, Anthony N Hollenber. Leptin and melanocortin signaling in the hypothalamus. Vitamins and hormones. vol 65. 2003-01-10. PMID:12481551. |
leptin's actions are mediated principally by target neurons in the hypothalamus where it acts to alter food intake, energy expenditure, and neuroendocrine-function. |
2003-01-10 |
2023-08-12 |
Not clear |
| Z A Archer, S M Rhind, P A Findlay, C E Kyle, L Thomas, M Marie, C L Ada. Contrasting effects of different levels of food intake and adiposity on LH secretion and hypothalamic gene expression in sheep. The Journal of endocrinology. vol 175. issue 2. 2003-01-06. PMID:12429036. |
body reserves (long-term) and food intake (short-term) both contribute nutritional feedback to the hypothalamus. |
2003-01-06 |
2023-08-12 |
Not clear |
| Z A Archer, S M Rhind, P A Findlay, C E Kyle, L Thomas, M Marie, C L Ada. Contrasting effects of different levels of food intake and adiposity on LH secretion and hypothalamic gene expression in sheep. The Journal of endocrinology. vol 175. issue 2. 2003-01-06. PMID:12429036. |
thus, the hypothalamus shows differential responses to steady-state adiposity as opposed to an increase in food intake, in terms of both reproductive neuroendocrine activity and hypothalamic appetite-regulating pathways. |
2003-01-06 |
2023-08-12 |
Not clear |
| Edmond Y W Chan, Jamal Nasir, Claire-Anne Gutekunst, Sarah Coleman, Alan Maclean, Alex Maas, Martina Metzler, Marina Gertsenstein, Christopher A Ross, Andràs Nagy, Michael R Hayde. Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Human molecular genetics. vol 11. issue 8. 2003-01-03. PMID:11971876. |
hap-1 is particularly enriched in the hypothalamus, which is well documented to regulate feeding behavior. |
2003-01-03 |
2023-08-12 |
mouse |
| A Sahu, L Nguyen, R M O'Dohert. Nutritional regulation of hypothalamic leptin receptor gene expression is defective in diet-induced obesity. Journal of neuroendocrinology. vol 14. issue 11. 2003-01-03. PMID:12421342. |
leptin action in the hypothalamus plays a critical role in maintaining normal food intake and body weight. |
2003-01-03 |
2023-08-12 |
rat |