| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John K Youn. Anatomical relationship between specialized astrocytes and leptin-sensitive neurones. Journal of anatomy. vol 201. issue 1. 2002-09-16. PMID:12171479. |
since bfabp has been shown to regulate the activity of an enzyme, fatty acid synthase, that has a potent influence upon the regulation of feeding by the hypothalamus, it was of interest to determine if bfabp + astrocytes are positioned to potentially influence the activity of feeding-regulating neurones. |
2002-09-16 |
2023-08-12 |
Not clear |
| Niels Vrang, Philip J Larsen, Peter Kristense. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151772. |
in the hypothalamus, cart mrna expression has been shown to be regulated by leptin, and cart peptides have been implicated in feeding behavior and in the regulation of the hpa-axis. |
2002-09-10 |
2023-08-12 |
rat |
| Rachel L Batterham, Michael A Cowley, Caroline J Small, Herbert Herzog, Mark A Cohen, Catherine L Dakin, Alison M Wren, Audrey E Brynes, Malcolm J Low, Mohammad A Ghatei, Roger D Cone, Stephen R Bloo. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature. vol 418. issue 6898. 2002-09-09. PMID:12167864. |
food intake is regulated by the hypothalamus, including the melanocortin and neuropeptide y (npy) systems in the arcuate nucleus. |
2002-09-09 |
2023-08-12 |
mouse |
| Philippa A Norto. Affect of serum leptin on nutritional status in renal disease. Journal of the American Dietetic Association. vol 102. issue 8. 2002-09-05. PMID:12171457. |
leptin, a hormone secreted by adipose tissue, decreases food intake via neuroendocrine systems in the hypothalamus in persons with normal renal function. |
2002-09-05 |
2023-08-12 |
Not clear |
| Eric Parker, Margaret Van Heek, Andrew Stamfor. Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. European journal of pharmacology. vol 440. issue 2-3. 2002-08-26. PMID:12007534. |
neuropeptide y stimulates food intake, inhibits energy expenditure, increases body weight and increases anabolic hormone levels by activating the neuropeptide y y(1) and y(5) receptors in the hypothalamus. |
2002-08-26 |
2023-08-12 |
mouse |
| Andrew L Gundlac. Galanin/GALP and galanin receptors: role in central control of feeding, body weight/obesity and reproduction? European journal of pharmacology. vol 440. issue 2-3. 2002-08-26. PMID:12007540. |
thus, while numerous studies have revealed the ability of galanin to stimulate food intake via actions at sites within the hypothalamus, and shown reliable changes in hypothalamic galanin synthesis in response to food ingestion; findings including the lack of a 'body weight/obesity' phenotype in galanin transgenic mouse strains and a lack of agonists/antagonists for galanin receptor subtypes have probably served to reduce enthusiasm. |
2002-08-26 |
2023-08-12 |
mouse |
| J Fadel, A Y Deutc. Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983323. |
among the neuropeptides found in the hypothalamus are the orexins, which are selectively expressed in the lateral hypothalamus and adjacent perifornical area and are critically involved in homeostatic regulatory processes, including arousal and feeding. |
2002-08-13 |
2023-08-12 |
rat |
| Angelo Del Parigi, Jean-Francois Gautier, Kewei Chen, Arline D Salbe, Eric Ravussin, Eric Reiman, P Antonio Tatarann. Neuroimaging and obesity: mapping the brain responses to hunger and satiation in humans using positron emission tomography. Annals of the New York Academy of Sciences. vol 967. 2002-08-02. PMID:12079866. |
the hypothalamus has a major role in the control of food intake. |
2002-08-02 |
2023-08-12 |
human |
| B Thoren. GLUT2 in pancreatic and extra-pancreatic gluco-detection (review). Molecular membrane biology. vol 18. issue 4. 2002-07-12. PMID:11780755. |
these include cells forming the hepatoportal vein glucose sensor, which controls glucose storage in the liver, counterregulation, food intake and glucose utilization by peripheral tissues and neurons in the hypothalamus and brainstem whose firing rates are modulated by local variations in glucose concentrations or, when not protected by a blood-brain barrier, directly by changes in blood glucose levels. |
2002-07-12 |
2023-08-12 |
mouse |
| Ryusuke Suzuki, Hisa Shimojima, Hisayuki Funahashi, Shigeo Nakajo, Shuori Yamada, Jian-Lian Guan, Shinobu Tsurugano, Kichiro Uehara, Yoichi Takeyama, Sakae Kikuyama, Seiji Shiod. Orexin-1 receptor immunoreactivity in chemically identified target neurons in the rat hypothalamus. Neuroscience letters. vol 324. issue 1. 2002-07-12. PMID:11983281. |
strong orexin receptor 1 (ox1r) immunoreactivity was detected in the hypothalamus including the arcuate, ventromedial, and tuberomammillary nuclei that are involved in feeding regulation. |
2002-07-12 |
2023-08-12 |
rat |
| Anoja S Attele, Zhi Q Shi, Chun Su Yua. Leptin, gut, and food intake. Biochemical pharmacology. vol 63. issue 9. 2002-07-10. PMID:12007560. |
leptin binds to specific receptors in the hypothalamus to mediate events that regulate feeding behavior. |
2002-07-10 |
2023-08-12 |
Not clear |
| J Barrenetxe, A C Villaro, L Guembe, I Pascual, M Muñoz-Navas, A Barber, M P Losta. Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes. Gut. vol 50. issue 6. 2002-07-10. PMID:12010881. |
leptin, a hormone mainly produced by fat cells, acts primarily on the hypothalamus regulating energy expenditure and food intake. |
2002-07-10 |
2023-08-12 |
mouse |
| K J Touchette, J A Carroll, G L Allee, R L Matteri, C J Dyer, L A Beausang, M E Zannell. Effect of spray-dried plasma and lipopolysaccharide exposure on weaned pigs: I. Effects on the immune axis of weaned pigs. Journal of animal science. vol 80. issue 2. 2002-07-03. PMID:11881933. |
feeding sdp resulted in reduced (p < 0.05) mrna expression of tumor necrosis factor-alpha (tnf-alpha) and interleukin-1beta (il-1beta) mrna in the adrenal gland, spleen, hypothalamus, pituitary gland, and liver. |
2002-07-03 |
2023-08-12 |
Not clear |
| Silvana Obici, Zhaohui Feng, George Karkanias, Denis G Baskin, Luciano Rossett. Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats. Nature neuroscience. vol 5. issue 6. 2002-06-19. PMID:12021765. |
thus, insulin receptors in discrete areas of the hypothalamus have a physiological role in the control of food intake, fat mass and hepatic action of insulin. |
2002-06-19 |
2023-08-12 |
rat |
| Huiyuan Zheng, Michele M Corkern, Scott M Crousillac, Laurel M Patterson, Curtis B Phifer, Hans-Rudolf Berthou. Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP. American journal of physiology. Regulatory, integrative and comparative physiology. vol 282. issue 6. 2002-06-11. PMID:12010760. |
agouti-related protein (agrp) is coexpressed with neuropeptide y (npy) in a population of neurons in the arcuate nucleus (arc) of the hypothalamus and stimulates food intake for up to 7 days if injected intracerebroventricularly. |
2002-06-11 |
2023-08-12 |
rat |
| Olivier Camand, Sophie Turban, Marc Abitbol, Michèle Guerre-Mill. Embryonic expression of the leptin receptor gene in mesoderm-derived tissues. Comptes rendus biologies. vol 325. issue 2. 2002-06-10. PMID:11980179. |
leptin acts on the hypothalamus to reduce food intake and on a number of non-neuronal tissues via specific receptors (lepr). |
2002-06-10 |
2023-08-12 |
mouse |
| Alessandro Laviano, Mariarita Russo, Francesca Freda, Filippo Rossi-Fanell. Neurochemical mechanisms for cancer anorexia. Nutrition (Burbank, Los Angeles County, Calif.). vol 18. issue 1. 2002-06-07. PMID:11827780. |
under normal conditions, the homeostasis of energy intake is maintained in the hypothalamus by 1) transducing metabolic and sensorial inputs arising from the periphery into neuronal response, 2) integrating the information originating from different tissues, and 3) triggering the appropriate feeding responses. |
2002-06-07 |
2023-08-12 |
human |
| Alessandro Laviano, Mariarita Russo, Francesca Freda, Filippo Rossi-Fanell. Neurochemical mechanisms for cancer anorexia. Nutrition (Burbank, Los Angeles County, Calif.). vol 18. issue 1. 2002-06-07. PMID:11827780. |
if cancer anorexia is considered a disruption of the physiologic mechanisms controlling energy intake, it is conceivable that its pathogenesis may lie in an abnormal input of information to the hypothalamus, its defective transduction and integration, or the induction of exaggerated and inappropriate feeding responses. |
2002-06-07 |
2023-08-12 |
human |
| A Thorsell, L Caberlotto, R Rimondini, M Heili. Leptin suppression of hypothalamic NPY expression and feeding, but not amygdala NPY expression and experimental anxiety. Pharmacology, biochemistry, and behavior. vol 71. issue 3. 2002-05-28. PMID:11830177. |
leptin decreases food intake through actions in the hypothalamus, partly through interactions with neuropeptide y (npy). |
2002-05-28 |
2023-08-12 |
human |
| S Nicolaidis, K Gerozissis, M Orosc. [Variations of hypothalamic and cortical prostaglandins and monoamines reveal transitions in arousal states: microdialysis study in the rat]. Revue neurologique. vol 157. issue 11 Pt 2. 2002-05-22. PMID:11924034. |
we focused on the paraventricular and ventromedial nuclei of the hypothalamus for their involvement in the relationships between feeding, metabolic rate and sleep, and the prefrontal cortex for its role in vigilance. |
2002-05-22 |
2023-08-12 |
rat |