| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Garcia, W G Hankins, K W Rusinia. Behavioral regulation of the milieu interne in man and rat. Science (New York, N.Y.). vol 185. issue 4154. 2002-01-11. PMID:11785521. |
ascending fibers bifurcate at the level of the pons and project toward the feeding areas of the hypothalamus and the cortex. |
2002-01-11 |
2023-08-12 |
human |
| T Sato, M M Meguid, S O Fetissov, C Chen, L Zhan. Hypothalamic dopaminergic receptor expressions in anorexia of tumor-bearing rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 6. 2002-01-02. PMID:11705777. |
our data provide evidence that postsynaptic dopaminergic receptor subtypes in the hypothalamus are involved in the regulation of meal size, meal number, and thus food intake in anorectic tb rats. |
2002-01-02 |
2023-08-12 |
rat |
| H Goïot, S Attoub, S Kermorgant, J P Laigneau, B Lardeux, T Lehy, M J Lewin, A Bad. Antral mucosa expresses functional leptin receptors coupled to STAT-3 signaling, which is involved in the control of gastric secretions in the rat. Gastroenterology. vol 121. issue 6. 2001-12-31. PMID:11729121. |
leptin is a circulating hormone that communicates the peripheral nutritional status to the hypothalamus, which controls food intake, energy expenditure, and body weight. |
2001-12-31 |
2023-08-12 |
rat |
| I Aprath-Husmann, K Röhrig, H Gottschling-Zeller, T Skurk, D Scriba, M Birgel, H Haune. Effects of leptin on the differentiation and metabolism of human adipocytes. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25. issue 10. 2001-12-13. PMID:11673767. |
leptin is an adipose protein regulating food intake in the hypothalamus. |
2001-12-13 |
2023-08-12 |
human |
| S Ludvigsen, L Thim, A M Blom, B S Wulf. Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry. vol 40. issue 31. 2001-11-01. PMID:11478874. |
cocaine and amphetamine regulated transcript (cart) peptide has been shown to be an anorectic peptide that inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide y and regulated by leptin in the hypothalamus. |
2001-11-01 |
2023-08-12 |
Not clear |
| K Lindell, P A Bennett, Y Itoh, I C Robinson, L M Carlsson, B Carlsso. Leptin receptor 5'untranslated regions in the rat: relative abundance, genomic organization and relation to putative response elements. Molecular and cellular endocrinology. vol 172. issue 1-2. 2001-09-20. PMID:11165038. |
the presence of a putative ere, close to the most frequently used transcriptional start sites of the leptin-r gene in the hypothalamus, provides a possible mechanism by which estrogen may exert its effects on food intake. |
2001-09-20 |
2023-08-12 |
mouse |
| L A Eckel, N Gear. Estradiol treatment increases feeding-induced c-Fos expression in the brains of ovariectomized rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 3. 2001-09-20. PMID:11506987. |
feeding increased the number of c-fos-positive cells in the nts, the paraventricular nucleus of the hypothalamus (pvn), and the central nucleus of the amygdala (cea) in oil-treated rats. |
2001-09-20 |
2023-08-12 |
rat |
| A Nogalska, J Swierczynsk. The age-related differences in obese and fatty acid synthase gene expression in white adipose tissue of rat. Biochimica et biophysica acta. vol 1533. issue 1. 2001-09-20. PMID:11514238. |
this suggests that the changes of fas gene expression occur in response to serum leptin concentration and that in mature rats the high level of ob gene expression and consequently the high leptin concentration protect the white adipose tissue cells against fat overload by two independent mechanisms: (a) preventing an increase of food intake through the leptin action on the hypothalamus; (b) inhibiting fas gene expression and consequently decreasing the rate of lipogenesis. |
2001-09-20 |
2023-08-12 |
rat |
| Y Uet. [Involvement of orexins/hypocretins in multiple physiological functions]. Journal of UOEH. vol 23. issue 2. 2001-09-06. PMID:11431960. |
the lha is known to be a feeding center in the hypothalamus. |
2001-09-06 |
2023-08-12 |
mouse |
| S Okamoto, K Kimura, M Sait. Anorectic effect of leptin is mediated by hypothalamic corticotropin-releasing hormone, but not by urocortin, in rats. Neuroscience letters. vol 307. issue 3. 2001-08-30. PMID:11438393. |
leptin is a key afferent signal that decreases food intake and increases energy expenditure by acting on the specific receptors in the hypothalamus. |
2001-08-30 |
2023-08-12 |
rat |
| Y Kameda, M Miura, T Nishimak. Localization of neuropeptide Y mRNA and peptide in the chicken hypothalamus and their alterations after food deprivation, dehydration, and castration. The Journal of comparative neurology. vol 436. issue 3. 2001-08-30. PMID:11438937. |
thus, it seems that npy neurons located in the mediobasal hypothalamus are involved in feeding behavior but not reproductive activity. |
2001-08-30 |
2023-08-12 |
chicken |
| D V Rayner, P Trayhur. Regulation of leptin production: sympathetic nervous system interactions. Journal of molecular medicine (Berlin, Germany). vol 79. issue 1. 2001-08-23. PMID:11327106. |
leptin is secreted primarily from white adipose tissue and stimulates long-form ob-rb receptors in the hypothalamus to decrease food intake and increase energy expenditure. |
2001-08-23 |
2023-08-12 |
Not clear |
| J H Park, H H Lee, S Y Na, S K Ju, Y J Lee, M K Lee, K L Ki. Recombinant expression of biologically active rat leptin in Escherichia coli. Protein expression and purification. vol 22. issue 1. 2001-08-23. PMID:11388800. |
leptin is a 16-kda nonglycosylated hormone that is produced in mature adipocytes and which acts primarily in the hypothalamus to reduce food intake and body weight. |
2001-08-23 |
2023-08-12 |
rat |
| C R Abbott, M Rossi, A M Wren, K G Murphy, A R Kennedy, S A Stanley, A N Zollner, D G Morgan, I Morgan, M A Ghatei, C J Small, S R Bloo. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459791. |
we studied the effect of the active fragment of cocaine- and amphetamine-regulated transcript, cocaine- and amphetamine-regulated transcript-(55-102), on feeding when injected into discrete nuclei of the hypothalamus. |
2001-08-16 |
2023-08-12 |
rat |
| C R Abbott, M Rossi, A M Wren, K G Murphy, A R Kennedy, S A Stanley, A N Zollner, D G Morgan, I Morgan, M A Ghatei, C J Small, S R Bloo. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459791. |
cocaine- and amphetamine-regulated transcript-(55-102) (0.04 nmol) elicited a delayed, but significant, increase in feeding in 24-h fasted rats after injection into the ventromedial nucleus (1-2 h, 261 +/- 60% of control; p < 0.05) and arcuate nucleus (1-2 h, 225 +/- 38% of control; p < 0.05) of the hypothalamus. |
2001-08-16 |
2023-08-12 |
rat |
| C R Abbott, M Rossi, A M Wren, K G Murphy, A R Kennedy, S A Stanley, A N Zollner, D G Morgan, I Morgan, M A Ghatei, C J Small, S R Bloo. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459791. |
administration of a higher dose of cocaine- and amphetamine-regulated transcript-(55-102) (0.2 nmol) elicited a significant increase in feeding after injection into the ventromedial nucleus (1-2 h, 1253 +/- 179% of control; p < 0.001), arcuate nucleus (1-2 h, 265 +/- 43% of control; p < 0.05), paraventricular nucleus (2-4 h food intake, 186 +/- 29% of control; p < 0.05), lateral hypothalamic area (2-4 h, 280 +/- 34% of control; p < 0.001), anterior hypothalamic area (2-4 h, 252 +/- 42% of control; p < 0.01), dorsomedial nucleus (2-4 h, 368 +/- 29% of control;p < 0.001) and supraoptic nucleus (2-4 h, 212 +/- 34% of control; p < 0.05) of the hypothalamus. |
2001-08-16 |
2023-08-12 |
rat |
| C R Abbott, M Rossi, A M Wren, K G Murphy, A R Kennedy, S A Stanley, A N Zollner, D G Morgan, I Morgan, M A Ghatei, C J Small, S R Bloo. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459791. |
administration of cocaine- and amphetamine-regulated transcript-(55-102) into the third ventricle of the hypothalamus resulted in an inhibition in feeding [0-4 h (0.4 nmol), 33 +/- 13% control; p < 0.001], but was associated with marked abnormalities in behavior, which may have interfered with feeding. |
2001-08-16 |
2023-08-12 |
rat |
| Y Saito, M Cheng, F M Leslie, O Civell. Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. The Journal of comparative neurology. vol 435. issue 1. 2001-07-26. PMID:11370009. |
within the hypothalamus, mchr mrna was moderately expressed in the ventromedial nucleus, arcuate nucleus, and zona incerta, all of which serve key roles in the neuronal circuitry of feeding. |
2001-07-26 |
2023-08-12 |
rat |
| S P Kelley, M A Nannini, A M Bratt, C W Hodg. Neuropeptide-Y in the paraventricular nucleus increases ethanol self-administration. Peptides. vol 22. issue 3. 2001-07-19. PMID:11287109. |
the paraventricular nucleus (pvn) of the hypothalamus is known to modulate feeding, obesity, and ethanol intake. |
2001-07-19 |
2023-08-12 |
rat |
| M J Morris, T Nguye. Does neuropeptide Y contribute to the anorectic action of amylin? Peptides. vol 22. issue 3. 2001-07-19. PMID:11287112. |
neuropeptide y (npy) is a potent feeding stimulant acting at the level of the hypothalamus. |
2001-07-19 |
2023-08-12 |
rat |