| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X Lin, H Volkoff, Y Narnaware, N J Bernier, P Peyon, R E Pete. Brain regulation of feeding behavior and food intake in fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 126. issue 4. 2000-11-28. PMID:10989336. |
in mammals, the orexigenic and anorexigenic neuronal systems are morphologically and functionally connected, forming an interconnected network in the hypothalamus to govern food intake and body weight. |
2000-11-28 |
2023-08-12 |
Not clear |
| X Lin, H Volkoff, Y Narnaware, N J Bernier, P Peyon, R E Pete. Brain regulation of feeding behavior and food intake in fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 126. issue 4. 2000-11-28. PMID:10989336. |
the brain hypothalamic area is associated with regulation of food intake, while sites outside the hypothalamus are also involved in this function. |
2000-11-28 |
2023-08-12 |
Not clear |
| M G Dube, S Pu, S P Kalra, P S Kalr. Melanocortin signaling is decreased during neurotoxin-induced transient hyperphagia and increased body-weight gain. Peptides. vol 21. issue 6. 2000-10-19. PMID:10958999. |
levels of alpha-melanocortin-stimulating hormone were also decreased in the micropunched paraventricular nucleus, dorsomedial nucleus, and perifornical hypothalamus, sites implicated in the control of food intake. |
2000-10-19 |
2023-08-12 |
rat |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
goldfish maintained on a daily scheduled feeding regimen display an increase in npy mrna levels in the telencephalon-preoptic area and hypothalamus shortly before feeding; however, a decrease occured in optic tectum-thalamus. |
2000-10-05 |
2023-08-12 |
Not clear |
| S Layé, G Gheusi, S Cremona, C Combe, K Kelley, R Dantzer, P Parne. Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 1. 2000-09-27. PMID:10896869. |
intraperitoneal administration of lps (5-10 microgram/mouse) induced a dramatic, but transient, decrease in food intake, associated with an enhanced expression of proinflammatory cytokine mrna (il-1beta, il-6, and tumor necrosis factor-alpha) in the hypothalamus. |
2000-09-27 |
2023-08-12 |
Not clear |
| S Layé, G Gheusi, S Cremona, C Combe, K Kelley, R Dantzer, P Parne. Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 1. 2000-09-27. PMID:10896869. |
intracerebroventricular pretreatment with il-1 receptor antagonist (4 microgram/mouse) attenuated lps-induced depression of food intake and totally blocked the lps-induced enhanced expression of proinflammatory cytokine mrna measured in the hypothalamus 1 h after treatment. |
2000-09-27 |
2023-08-12 |
Not clear |
| D E Mullins, M Guzzi, L Xia, E M Parke. Pharmacological characterization of the cloned neuropeptide Y y(6) receptor. European journal of pharmacology. vol 395. issue 2. 2000-09-06. PMID:10794812. |
in mice, the neuropeptide y y(6) receptor is also expressed in the hypothalamus, suggesting that it too may function as a feeding receptor in this species. |
2000-09-06 |
2023-08-12 |
mouse |
| J E Hall, M W Brands, D A Hildebrandt, J Kuo, S Fitzgeral. Role of sympathetic nervous system and neuropeptides in obesity hypertension. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 33. issue 6. 2000-08-28. PMID:10829088. |
leptin is produced mainly in adipocytes and is believed to regulate energy balance by acting on the hypothalamus to reduce food intake and to increase energy expenditure via sympathetic activation. |
2000-08-28 |
2023-08-12 |
mouse |
| M W Sleeman, K D Anderson, P D Lambert, G D Yancopoulos, S J Wiegan. The ciliary neurotrophic factor and its receptor, CNTFR alpha. Pharmaceutica acta Helvetiae. vol 74. issue 2-3. 2000-08-09. PMID:10812968. |
when administered systemically, cntf activates downstream signaling molecules such as stat-3 in areas of the hypothalamus which regulate food intake. |
2000-08-09 |
2023-08-12 |
mouse |
| M D Li, J K Kane, S L Parker, K McAllen, S G Matta, B M Shar. Nicotine administration enhances NPY expression in the rat hypothalamus. Brain research. vol 867. issue 1-2. 2000-08-04. PMID:10837809. |
to determine whether the effects of nicotine on food intake and body weight were related to neuropeptide y (npy) expression, semi-quantitative reverse transcription-polymerase chain reaction (rt-pcr) and radioimmunoassay were utilized to measure npy mrna and peptide levels in various regions of the hypothalamus. |
2000-08-04 |
2023-08-12 |
human |
| N S Brown, A Smart, V Sharma, M L Brinkmeier, L Greenlee, S A Camper, D R Jensen, R H Eckel, W Krezel, P Chambon, B R Hauge. Thyroid hormone resistance and increased metabolic rate in the RXR-gamma-deficient mouse. The Journal of clinical investigation. vol 106. issue 1. 2000-07-27. PMID:10880050. |
rxr-gamma, which is also expressed in skeletal muscle and the hypothalamus, may have a direct effect on muscle metabolism, regulation of food intake, or thyrotropin-releasing hormone levels in the hypothalamus. |
2000-07-27 |
2023-08-12 |
mouse |
| C Bishop, P J Currie, D V Coscin. Effects of three neurochemical stimuli on delayed feeding and energy metabolism. Brain research. vol 865. issue 1. 2000-07-21. PMID:10814743. |
infusions of norepinephrine (ne), the gamma-aminobutyric acid agonist, muscimol (mus), or neuropeptide y (npy) into the paraventricular nucleus (pvn) of the hypothalamus all increase food intake. |
2000-07-21 |
2023-08-12 |
rat |
| A Juréus, M J Cunningham, M E McClain, D K Clifton, R A Steine. Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat. Endocrinology. vol 141. issue 7. 2000-07-20. PMID:10875277. |
the presence of galp mrna in the hypothalamus and pituitary and its regulation by leptin suggests that galp may have important neuroendocrine functions, including the physiological regulation of feeding, metabolism, and reproduction. |
2000-07-20 |
2023-08-12 |
rat |
| I Mizuno, Y Okimura, Y Takahashi, H Kaji, H Abe, K Chihar. Leptin stimulates basal and GHRH-induced GH release from cultured rat anterior pituitary cells in vitro. The Kobe journal of medical sciences. vol 45. issue 5. 2000-07-19. PMID:10853188. |
leptin, the product of ob gene, is secreted from adipocytes and appears to regulate food intake and energy expenditure through its receptor in the hypothalamus. |
2000-07-19 |
2023-08-12 |
rat |
| M S Kim, M Rossi, S Abusnana, D Sunter, D G Morgan, C J Small, C M Edwards, M M Heath, S A Stanley, L J Seal, J R Bhatti, D M Smith, M A Ghatei, S R Bloo. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes. vol 49. issue 2. 2000-07-06. PMID:10868932. |
the melanocortin-4 receptor (mc4r) in the hypothalamus is thought to be important in physiological regulation of food intake. |
2000-07-06 |
2023-08-12 |
rat |
| I ANDIK, J BANK, S DONHOFFE. [Effect of hypothalamus lesions on the food intake & food selection of rats]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie. vol 231. issue 1. 2000-07-01. PMID:13526775. |
[effect of hypothalamus lesions on the food intake & food selection of rats]. |
2000-07-01 |
2023-08-12 |
rat |
| Z Díaz-Cabiale, J A Narváez, M Petersson, K Uvnäs-Moberg, K Fux. Oxytocin/alpha(2)-Adrenoceptor interactions in feeding responses. Neuroendocrinology. vol 71. issue 3. 2000-06-28. PMID:10729792. |
the modulation of alpha(2)-adrenoceptor-induced food intake by oxytocin has been evaluated in studies on food intake and by quantitative receptor autoradiography in the hypothalamus and the amygdala of the rat. |
2000-06-28 |
2023-08-12 |
rat |
| Z Díaz-Cabiale, J A Narváez, M Petersson, K Uvnäs-Moberg, K Fux. Oxytocin/alpha(2)-Adrenoceptor interactions in feeding responses. Neuroendocrinology. vol 71. issue 3. 2000-06-28. PMID:10729792. |
these findings suggest the existence of an antagonistic oxytocin/alpha(2)-receptor interaction in the hypothalamus and amygdala that may be of relevance for the demonstrated modulation of alpha(2)-adrenoceptor-induced feeding responses by oxytocin. |
2000-06-28 |
2023-08-12 |
rat |
| F Rohner-Jeanrenau. Neuroendocrine regulation of nutrient partitioning. Annals of the New York Academy of Sciences. vol 892. 2000-06-28. PMID:10842667. |
leptin is a satiety factor which acts within the hypothalamus to decrease the levels of several neuropeptides stimulating food intake (among them, neuropeptide y [npy]), while increasing those that inhibit food intake. |
2000-06-28 |
2023-08-12 |
rat |
| K Shimamot. [Insulin resistance syndrome and hypertension]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 75. issue 1. 2000-06-14. PMID:10736756. |
as a result, the hypothalamus adjusts food intake, thermogenesis, and energy expenditure appropriately. |
2000-06-14 |
2023-08-12 |
Not clear |