| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Peyon, H Saied, X Lin, R E Pete. Preprotachykinin gene expression in goldfish brain: sexual, seasonal, and postprandial variations. Peptides. vol 21. issue 2. 2000-06-08. PMID:10764949. |
in addition, the postprandial changes in gamma-ppt gene expression in the olfactory bulbs and hypothalamus suggest that tachykinin peptides are involved in regulation of feeding behavior in goldfish. |
2000-06-08 |
2023-08-12 |
Not clear |
| M J Glass, C J Billington, A S Levin. Opioids and food intake: distributed functional neural pathways? Neuropeptides. vol 33. issue 5. 2000-06-02. PMID:10657513. |
for example, opioids in the hindbrain might be involved in both sensory and metabolic aspects of food intake, those in the amygdala in processing of 'emotional' properties of foods, and those in the hypothalamus in energy needs. |
2000-06-02 |
2023-08-12 |
Not clear |
| Y Yamamoto, Y Ueta, R Serino, M Nomura, I Shibuya, H Yamashit. Effects of food restriction on the hypothalamic prepro-orexin gene expression in genetically obese mice. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758342. |
although the levels of the expression of the prepro-orexin gene in obese mice were significantly lower than those in c57bl/6j mice during feeding ad libitum, food restriction caused an increase in the expression of the prepro-orexin gene in the hypothalamus of obese mice. |
2000-05-31 |
2023-08-12 |
mouse |
| S Hao, Y Avraham, R Mechoulam, E M Berr. Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. European journal of pharmacology. vol 392. issue 3. 2000-05-17. PMID:10762668. |
we studied the effect of very low dose anandamide (0.001 mg/kg) administration on food intake, cognitive function and catecholaminergic and serotonergic pathways in two murine brain areas concerned with appetite (hypothalamus) and learning (hippocampus), and the peripheral corticosterone response to the stress of 40% diet restriction. |
2000-05-17 |
2023-08-12 |
mouse |
| J Duhault, M Boulanger, S Chamorro, J A Boutin, O Della Zuana, E Douillet, J L Fauchère, M Félétou, M Germain, B Husson, A M Vega, P Renard, F Tisseran. Food intake regulation in rodents: Y5 or Y1 NPY receptors or both? Canadian journal of physiology and pharmacology. vol 78. issue 2. 2000-05-16. PMID:10737680. |
neuropeptide y (npy), one of the most abundant peptides in rat and human brains, appears to act in the hypothalamus to stimulate feeding. |
2000-05-16 |
2023-08-12 |
human |
| M R Jain, T L Horvath, P S Kalra, S P Kalr. Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats. Regulatory peptides. vol 87. issue 1-3. 2000-05-02. PMID:10710284. |
neuropeptide y (npy) produced in the arcuate nucleus (arc) of the hypothalamus stimulates feeding both directly by activating npy receptors and indirectly through release of the orexigenic peptides, galanin and beta-endorphin (beta-end), in the paraventricular nucleus (pvn) and surrounding neural sites. |
2000-05-02 |
2023-08-12 |
rat |
| M W Schwartz, S C Woods, D Porte, R J Seeley, D G Baski. Central nervous system control of food intake. Nature. vol 404. issue 6778. 2000-04-27. PMID:10766253. |
although each new signalling pathway discovered in the hypothalamus is a potential target for drug development in the treatment of obesity, the growing number of such signalling molecules indicates that food intake is controlled by a highly complex process. |
2000-04-27 |
2023-08-12 |
human |
| A Ballinger, T El-Haj, D Perrett, J Turvill, O Obeid, S Dryden, G Williams, M J Farthin. The role of medial hypothalamic serotonin in the suppression of feeding in a rat model of colitis. Gastroenterology. vol 118. issue 3. 2000-04-07. PMID:10702205. |
serotonin (5-hydroxytryptamine [5-ht]) is a potent inhibitor of feeding, and its release from the hypothalamus is stimulated by il-1. |
2000-04-07 |
2023-08-12 |
rat |
| M López, L Seoane, M C García, F Lago, F F Casanueva, R Señarís, C Diégue. Leptin regulation of prepro-orexin and orexin receptor mRNA levels in the hypothalamus. Biochemical and biophysical research communications. vol 269. issue 1. 2000-03-31. PMID:10694474. |
these data provide direct evidence for an additional mechanism of adaptation of the hypothalamus to food deprivation and for a new effect of leptin in the regulation of food intake. |
2000-03-31 |
2023-08-12 |
rat |
| H Kanemaru, H Nakamura, H Isayama, M Kawabuchi, N Tashir. Efferent connections of the anterior hypothalamic nucleus: a biocytin study in the cat. Brain research bulletin. vol 51. issue 3. 2000-03-30. PMID:10718514. |
in the hypothalamus, the ah projections terminated mainly in the medial regions which are related to the defensive, reproductive and feeding behaviors, and autonomic functions. |
2000-03-30 |
2023-08-12 |
cat |
| B Meiste. Control of food intake via leptin receptors in the hypothalamus. Vitamins and hormones. vol 59. 2000-03-28. PMID:10714243. |
control of food intake via leptin receptors in the hypothalamus. |
2000-03-28 |
2023-08-12 |
mouse |
| B Meiste. Control of food intake via leptin receptors in the hypothalamus. Vitamins and hormones. vol 59. 2000-03-28. PMID:10714243. |
food intake is regulated via neural circuits located in the hypothalamus. |
2000-03-28 |
2023-08-12 |
mouse |
| B Meiste. Control of food intake via leptin receptors in the hypothalamus. Vitamins and hormones. vol 59. 2000-03-28. PMID:10714243. |
leptin inhibits food intake and increases energy expenditure via an interaction with specific leptin receptors located in the hypothalamus. |
2000-03-28 |
2023-08-12 |
mouse |
| S Okamoto, Y Irie, I Ishikawa, K Kimura, Masayuki Sait. Central leptin suppresses splenic lymphocyte functions through activation of the corticotropin-releasing hormone-sympathetic nervous system. Brain research. vol 855. issue 1. 2000-03-17. PMID:10650150. |
leptin is one of the key afferent signals that regulate food intake and energy expenditure by acting on specific receptors in the hypothalamus. |
2000-03-17 |
2023-08-12 |
rat |
| R Hanada, M Nakazato, S Matsukura, N Murakami, H Yoshimatsu, T Sakat. Differential regulation of melanin-concentrating hormone and orexin genes in the agouti-related protein/melanocortin-4 receptor system. Biochemical and biophysical research communications. vol 268. issue 1. 2000-03-01. PMID:10652218. |
agouti protein and agouti-related protein (agrp) antagonize alpha-melanocyte-stimulating hormone that binds to and activates the melanocortin-4 receptor (mc4-r) in the hypothalamus, thereby stimulating food intake. |
2000-03-01 |
2023-08-12 |
mouse |
| S Ikeda, N Shiva, A Ikeda, R S Smith, S Nusinowitz, G Yan, T R Lin, S Chu, J R Heckenlively, M A North, J K Naggert, P M Nishina, M P Duya. Retinal degeneration but not obesity is observed in null mutants of the tubby-like protein 1 gene. Human molecular genetics. vol 9. issue 2. 2000-02-28. PMID:10607826. |
however, in contrast to tubby mice, tulp1 (-/-)mice exhibited normal hearing ability and, surprisingly, normal body weight despite the fact that both tub and tulp1 are expressed in the same neurons within the hypothalamus in areas known to be involved in feeding behavior and energy homeo stasis. |
2000-02-28 |
2023-08-12 |
mouse |
| M A Cowley, N Pronchuk, W Fan, D M Dinulescu, W F Colmers, R D Con. Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron. vol 24. issue 1. 2000-02-25. PMID:10677034. |
we demonstrate that individual neurons within the paraventricular nucleus of the hypothalamus (pvh) are capable of detection and integration of orexigenic (neuropeptide y [npy]) and anorexigenic (melanocortin) signals, that npy and melanocortins are functional antagonists of each other within the pvh in the regulation of feeding behavior, and that melanocortin administration within the pvh regulates both feeding behavior and energy expenditure. |
2000-02-25 |
2023-08-12 |
Not clear |
| M Varma, J K Chai, M M Meguid, A Laviano, J R Gleason, Z J Yang, V Blah. Effect of estradiol and progesterone on daily rhythm in food intake and feeding patterns in Fischer rats. Physiology & behavior. vol 68. issue 1-2. 2000-01-31. PMID:10627068. |
because estrogens modulate feeding activity via their action on the hypothalamus, and because there is a diurnal rhythm in the expression of cytoplasmic estrogen receptors and in estrogen binding activity, the present study examined the effects of ovariectomy and later hormone therapy on acute changes in body weight, and on the meal number-to-meal size relationship as reflected by food intake in the dark/light feeding patterns, in adult female rats in the intact state and after ovariectomy. |
2000-01-31 |
2023-08-12 |
rat |
| T Morimoto, Y Yamamoto, J I Mobarakeh, K Yanai, T Watanabe, T Watanabe, A Yamatodan. Involvement of the histaminergic system in leptin-induced suppression of food intake. Physiology & behavior. vol 67. issue 5. 2000-01-12. PMID:10604837. |
the ob gene product leptin is secreted from white adipose tissue, and may regulate food intake by acting on the hypothalamus in the central nervous system. |
2000-01-12 |
2023-08-12 |
mouse |
| A Kanatani, T Kanno, A Ishihara, M Hata, A Sakuraba, T Tanaka, Y Tsuchiya, T Mase, T Fukuroda, T Fukami, M Ihar. The novel neuropeptide Y Y(1) receptor antagonist J-104870: a potent feeding suppressant with oral bioavailability. Biochemical and biophysical research communications. vol 266. issue 1. 2000-01-06. PMID:10581170. |
neuropeptide y (npy) is known to induce robust feeding through the action of npy receptors in the hypothalamus. |
2000-01-06 |
2023-08-12 |
human |