| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Hee Kim, Kyung-Ah Cho, Minhwa Park, Julie A Webster, So-Youn Woo, Kyung-Ha Ry. Conditioned medium from tonsil‑derived mesenchymal stem cells promotes adiponectin production. Molecular medicine reports. vol 16. issue 5. 2018-06-07. PMID:28849047. |
previously, we reported that tonsil‑derived msc conditioned medium (t‑msc cm) produces visceral fat reducing effects. |
2018-06-07 |
2023-08-13 |
mouse |
| Abu Musa Md Talimur Reza, Yun-Jung Choi, Hideyo Yasuda, Jin-Hoi Ki. Human adipose mesenchymal stem cell-derived exosomal-miRNAs are critical factors for inducing anti-proliferation signalling to A2780 and SKOV-3 ovarian cancer cells. Scientific reports. vol 6. 2018-06-04. PMID:27929108. |
here, we showed that human adipose msc (hamsc)-derived conditioned medium (cm) exhibited inhibitory effects on a2780 human ovarian cancer cells by blocking the cell cycle, and activating mitochondria-mediated apoptosis signalling. |
2018-06-04 |
2023-08-13 |
human |
| Helen Kennelly, Bernard P Mahon, Karen Englis. Human mesenchymal stromal cells exert HGF dependent cytoprotective effects in a human relevant pre-clinical model of COPD. Scientific reports. vol 6. 2018-05-29. PMID:27922052. |
human msc therapy and msc conditioned media exerted significant cytoprotective effects when administered early at the onset of the disease. |
2018-05-29 |
2023-08-13 |
human |
| Helen Kennelly, Bernard P Mahon, Karen Englis. Human mesenchymal stromal cells exert HGF dependent cytoprotective effects in a human relevant pre-clinical model of COPD. Scientific reports. vol 6. 2018-05-29. PMID:27922052. |
msc cell therapy was more effective than msc conditioned medium in this emphysema model. |
2018-05-29 |
2023-08-13 |
human |
| Laura Mercatali, Federico La Manna, Giacomo Miserocchi, Chiara Liverani, Alessandro De Vita, Chiara Spadazzi, Alberto Bongiovanni, Federica Recine, Dino Amadori, Martina Ghetti, Toni Ibrahi. Tumor-Stroma Crosstalk in Bone Tissue: The Osteoclastogenic Potential of a Breast Cancer Cell Line in a Co-Culture System and the Role of EGFR Inhibition. International journal of molecular sciences. vol 18. issue 8. 2018-04-17. PMID:28758931. |
we evaluated the osteoclastogenesis modulation of human peripheral blood monocytes (pbmc) indirectly induced by the conditioned medium (cm) of the human bc cell line scp2, cultured singly or with msc. |
2018-04-17 |
2023-08-13 |
human |
| Chuan Lv, Haiying Dai, Mengyan Sun, Hui Zhao, Kai Wu, Ji Zhu, Yuchong Wang, Xian Cao, Zhaofan Xia, Chunyu Xu. Mesenchymal stem cells induce epithelial mesenchymal transition in melanoma by paracrine secretion of transforming growth factor-β. Melanoma research. vol 27. issue 2. 2018-02-23. PMID:28079609. |
b16 melanoma cells treated by msc conditioned medium (cm), showed significantly enhanced migration and invasion, which was also confirmed in a lung metastasis mice model in vivo. |
2018-02-23 |
2023-08-13 |
mouse |
| Karen L Lankford, Edgardo J Arroyo, Katarzyna Nazimek, Krzysztof Bryniarski, Philip W Askenase, Jeffery D Kocsi. Intravenously delivered mesenchymal stem cell-derived exosomes target M2-type macrophages in the injured spinal cord. PloS one. vol 13. issue 1. 2018-02-15. PMID:29293592. |
preliminary studies and a recent report [2] suggest that the effects of intravenous (iv) infusion of mscs could be mimicked by iv infusion of exosomes isolated from conditioned media of msc cultures (mscexos). |
2018-02-15 |
2023-08-13 |
rat |
| Joni H Ylostalo, Nikolay Bazhanov, Arezoo Mohammadipoor, Thomas J Bartos. Production and Administration of Therapeutic Mesenchymal Stem/Stromal Cell (MSC) Spheroids Primed in 3-D Cultures Under Xeno-free Conditions. Journal of visualized experiments : JoVE. issue 121. 2018-01-08. PMID:28362380. |
specifically, we first describe methods to generate spherical msc micro-tissues or 'spheroids' in hanging drops using xf medium and demonstrate how the spheres and conditioned medium (cm) can be harvested for various applications. |
2018-01-08 |
2023-08-13 |
mouse |
| Massimiliano Gnecchi, Patrizia Danieli, Giuseppe Malpasso, Maria Chiara Ciuffred. Paracrine Mechanisms of Mesenchymal Stem Cells in Tissue Repair. Methods in molecular biology (Clifton, N.J.). vol 1416. 2017-12-13. PMID:27236669. |
this hypothesis is supported by pre-clinical studies demonstrating equal or even improved organ function upon infusion of msc-derived conditioned medium (msc-cm) compared with msc transplantation. |
2017-12-13 |
2023-08-13 |
Not clear |
| Patrizia Danieli, Giuseppe Malpasso, Maria Chiara Ciuffreda, Massimiliano Gnecch. Testing the Paracrine Properties of Human Mesenchymal Stem Cells Using Conditioned Medium. Methods in molecular biology (Clifton, N.J.). vol 1416. 2017-12-13. PMID:27236688. |
the conditioned medium (cm) derived from msc can be used both in vitro and in vivo to test specific paracrine effects or to screen putative paracrine/autocrine mediators by proteomics.in this chapter, we describe a straightforward method to prepare msc-derived cm. |
2017-12-13 |
2023-08-13 |
human |
| Seiichiro Ishihara, David R Inman, Wan-Ju Li, Suzanne M Ponik, Patricia J Keel. Mechano-Signal Transduction in Mesenchymal Stem Cells Induces Prosaposin Secretion to Drive the Proliferation of Breast Cancer Cells. Cancer research. vol 77. issue 22. 2017-12-12. PMID:28972074. |
on a stiff matrix, msc cultured with conditioned media from mammary cancer cells expressed increased levels of α-smooth muscle actin, a marker of caf, compared with msc cultured on a soft matrix. |
2017-12-12 |
2023-08-13 |
Not clear |
| Yakov Sh Schwartz, Sergey N Belogorodtsev, Pavel N Filimonov, Andrey G Cherednichenko, Sergey V Pustylnikov, Vladimir A Krasno. BCG infection in mice is promoted by naïve mesenchymal stromal cells (MSC) and suppressed by poly(A:U)-conditioned MSC. Tuberculosis (Edinburgh, Scotland). vol 101. 2017-10-31. PMID:27865382. |
the effects of administration of naïve msc (nmsc) or conditioned msc (cmsc) on the course of mycobacterial infection were studied. |
2017-10-31 |
2023-08-13 |
mouse |
| Joji Kusuyama, Chang Hwan Seong, Tomokazu Ohnishi, Kenjiro Bandow, Tetsuya Matsuguch. 10. Low-Intensity Pulsed Ultrasound (LIPUS) Stimulation Helps to Maintain the Differentiation Potency of Mesenchymal Stem Cells by Induction in Nanog Protein Transcript Levels and Phosphorylation. Journal of orthopaedic trauma. vol 30. issue 8. 2017-09-25. PMID:27441771. |
the treatments of the conditioned medium from lipus-stimulated msc and exogenous atp promoted nanog expression. |
2017-09-25 |
2023-08-13 |
Not clear |
| Kim De Veirman, Jinheng Wang, Song Xu, Xavier Leleu, Eddy Himpe, Ken Maes, Elke De Bruyne, Els Van Valckenborgh, Karin Vanderkerken, Eline Menu, Ivan Van Rie. Induction of miR-146a by multiple myeloma cells in mesenchymal stromal cells stimulates their pro-tumoral activity. Cancer letters. vol 377. issue 1. 2017-07-03. PMID:27102001. |
here, we examined the mirna changes in human msc after culture with conditioned medium of mm cells and found 19 dysregulated mirnas, including upregulated mir-146a. |
2017-07-03 |
2023-08-13 |
human |
| Sofia Avnet, Gemma Di Pompo, Tokuhiro Chano, Costantino Errani, Arig Ibrahim-Hashim, Robert J Gillies, Davide Maria Donati, Nicola Baldin. Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation. International journal of cancer. vol 140. issue 6. 2017-06-21. PMID:27888521. |
conditioned media or co-culture with normal msc previously incubated with short-term acidosis (ph 6.8 for 10 hr, h |
2017-06-21 |
2023-08-13 |
Not clear |
| Emer F Cahill, Helen Kennelly, Fiona Carty, Bernard P Mahon, Karen Englis. Hepatocyte Growth Factor Is Required for Mesenchymal Stromal Cell Protection Against Bleomycin-Induced Pulmonary Fibrosis. Stem cells translational medicine. vol 5. issue 10. 2017-06-19. PMID:27388243. |
msc conditioned media (cm) enhanced wound closure and inhibited apoptosis of pulmonary cells in vitro. |
2017-06-19 |
2023-08-13 |
Not clear |
| Chizuka Obara, Ken-Ichi Tomiyama, Kazuya Takizawa, Rafiqul Islam, Takeshi Yasuda, Takaya Gotoh, Katsushi Tajim. Characteristics of three-dimensional prospectively isolated mouse bone marrow mesenchymal stem/stromal cell aggregates on nanoculture plates. Cell and tissue research. vol 366. issue 1. 2017-05-16. PMID:27100525. |
conditioned medium from 3-d msc cultures promoted more capillary formation than that of 2-d mscs in an in vitro tube formation assay. |
2017-05-16 |
2023-08-13 |
mouse |
| Yuan Yao, Chen Huang, Ping Gu, Tieqiao We. Combined MSC-Secreted Factors and Neural Stem Cell Transplantation Promote Functional Recovery of PD Rats. Cell transplantation. vol 25. issue 6. 2017-03-06. PMID:26607204. |
in this study, we prepared a conditioned medium (cm) using lyophilized msc culture medium that contained the secretome of mscs and applied this cm to the culture of neural stem cells (cm-nscs) for the transplantation of pd model rats. |
2017-03-06 |
2023-08-13 |
rat |
| Xiao-Bing Wu, Yang Liu, Gui-Hua Wang, Xiao Xu, Yang Cai, Hong-Yi Wang, Yan-Qi Li, Hong-Fang Meng, Fu Dai, Ji-De Ji. Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-κB activation. Scientific reports. vol 6. 2016-12-19. PMID:26892992. |
in vitro analysis of colorectal cancer cell lines cultured in msc conditioned media (msc-cm) showed that msc-cm significantly promoted the progression of the cancer cells by enhancing cell proliferation, migration and colony formation. |
2016-12-19 |
2023-08-13 |
mouse |
| Kathleen M McAndrews, Daniel J McGrail, Nithin Ravikumar, Michelle R Dawso. Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β. Scientific reports. vol 5. 2016-10-11. PMID:26585689. |
treatment with msc conditioned media or recombinant tgf-β1 elicits a similar migration response to coculture. |
2016-10-11 |
2023-08-13 |
Not clear |