| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue-Ru Ji, Zhou-Xin Yang, Li-Na Li, Zhi-Bo Han, Ying Chi, Zhong-Chao Ha. [IL-1β promotes the hematopoietic support of human umbilical cord mesenchymal stem cells]. Zhongguo shi yan xue ye xue za zhi. vol 21. issue 4. 2014-05-01. PMID:23998602. |
the results showed that the conditioned culture medium of huc-msc with il-1β enhanced the ability to form colony of cd34(+) cells, especially cfu-g and cfu-gm in vitro; il-1β promoted the mrna expression of gm-csf, g-csf, il-6 on msc; il-1β also promoted the secretion of gm-csf, g-csf, and il-6 protein from huc-msc. |
2014-05-01 |
2023-08-12 |
human |
| Hui Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau-Habermann, Niko Hensel, Dongya Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petr. Therapeutic potential of mesenchymal stromal cells and MSC conditioned medium in Amyotrophic Lateral Sclerosis (ALS)--in vitro evidence from primary motor neuron cultures, NSC-34 cells, astrocytes and microglia. PloS one. vol 8. issue 9. 2014-04-28. PMID:24069165. |
therapeutic potential of mesenchymal stromal cells and msc conditioned medium in amyotrophic lateral sclerosis (als)--in vitro evidence from primary motor neuron cultures, nsc-34 cells, astrocytes and microglia. |
2014-04-28 |
2023-08-12 |
mouse |
| Hui Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau-Habermann, Niko Hensel, Dongya Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petr. Therapeutic potential of mesenchymal stromal cells and MSC conditioned medium in Amyotrophic Lateral Sclerosis (ALS)--in vitro evidence from primary motor neuron cultures, NSC-34 cells, astrocytes and microglia. PloS one. vol 8. issue 9. 2014-04-28. PMID:24069165. |
in primary motor neurons, nsc-34 cells and astrocytes, msc conditioned medium (msc cm) attenuated staurosporine (sts) - induced apoptosis in a concentration-dependent manner. |
2014-04-28 |
2023-08-12 |
mouse |
| Renaud Manuguerra-Gagné, Patrick R Boulos, Ahmed Ammar, François A Leblond, Gorazd Krosl, Vincent Pichette, Mark R Lesk, Denis-Claude Ro. Transplantation of mesenchymal stem cells promotes tissue regeneration in a glaucoma model through laser-induced paracrine factor secretion and progenitor cell recruitment. Stem cells (Dayton, Ohio). vol 31. issue 6. 2014-04-17. PMID:23495088. |
this robust effect was attributable to paracrine factors from stressed msc, as injection of conditioned medium from msc exposed to low but not to normal oxygen levels resulted in an immediate decrease in iop. |
2014-04-17 |
2023-08-12 |
Not clear |
| Mohamed Talaat Abdel Aziz, Hussien Mostafa Khaled, Ali El Hindawi, Nagwa Kamal Roshdy, Laila A Rashed, Dina Sabry, Amira A Hassouna, Fatma Taha, Walaa Ibrahim Al. Effect of mesenchymal stem cells and a novel curcumin derivative on Notch1 signaling in hepatoma cell line. BioMed research international. vol 2013. 2014-04-07. PMID:24024180. |
hepg2 cells were divided into hepg2 control group, hepg2 cells treated with msc conditioned medium (mscs cm), hepg2 cells treated with a ncd, hepg2 cells treated with mscs cm and ncd, and hepg2 cells treated with mscs cm (cm of mscs pretreated with a ncd). |
2014-04-07 |
2023-08-12 |
Not clear |
| Angeliki Xagorari, Eleni Siotou, Minas Yiangou, Eleftheria Tsolaki, Dimitris Bougiouklis, Leonidas Sakkas, Athanassios Fassas, Achilles Anagnostopoulo. Protective effect of mesenchymal stem cell-conditioned medium on hepatic cell apoptosis after acute liver injury. International journal of clinical and experimental pathology. vol 6. issue 5. 2013-11-27. PMID:23638214. |
the aim of this study was to investigate the role of mesenchymal stem cell (msc) conditioned medium (cm(msc)) on apoptosis of cultured mouse primary hepatocytes after in vivo carbon tetrachloride (ccl4)-induced acute liver injury. |
2013-11-27 |
2023-08-12 |
mouse |
| Antonio Uccell. Mesenchymal stem cells exert a remarkable regenerative effect requiring minimal CNS integration: commentary on: "Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function" by Voulgari-Kokota et al. Experimental neurology. vol 247. 2013-11-26. PMID:23384664. |
in a recent paper from voulgari-kokota and colleagues in the july issue of experimental neurology it was shown that bone marrow-derived mesenchymal stem cells (msc) can protect against glutamate excitotoxicity in a mouse model of temporal lobe epilepsy and that conditioned medium from msc could rescue primary cortical neurons from glutamate-receptor induced cell death. |
2013-11-26 |
2023-08-12 |
mouse |
| Rongpei Wu, Guihua Liu, Shantaram Bharadwaj, Yuanyuan Zhan. Isolation and myogenic differentiation of mesenchymal stem cells for urologic tissue engineering. Methods in molecular biology (Clifton, N.J.). vol 1001. 2013-09-03. PMID:23494421. |
for example, msc can differentiate into a smooth muscle cell (smc) phenotype in vitro when exposed to stimuli such as conditioned medium derived from smc cultures or specific myogenic growth factors (pdgf-bb, hgf, tgf-β). |
2013-09-03 |
2023-08-12 |
human |
| Amandine F G Godier-Furnémont, Yared Tekabe, Maria Kollaros, George Eng, Alfredo Morales, Gordana Vunjak-Novakovic, Lynne L Johnso. Noninvasive imaging of myocyte apoptosis following application of a stem cell-engineered delivery platform to acutely infarcted myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 54. issue 6. 2013-08-01. PMID:23616583. |
this study aimed to test the hypothesis that apoptosis imaging can detect the cardioprotective effects of a conditioned msc patch grafted in a rat model of acute myocardial infarction. |
2013-08-01 |
2023-08-12 |
rat |
| Ivy A W Ho, Han C Toh, Wai H Ng, Yuan L Teo, Chang M Guo, Kam M Hui, Paula Y P La. Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis. Stem cells (Dayton, Ohio). vol 31. issue 1. 2013-06-24. PMID:23034897. |
using endothelial progenitor cells (epc) from healthy donors and huvec endothelial cells, the extent of epc recruitment and capacity to form endothelial tubes was significantly impaired in conditioned media derived from msc/glioma coculture, suggesting that msc suppressed tumor angiogenesis through the release of antiangiogenic factors. |
2013-06-24 |
2023-08-12 |
human |
| Zhi-Bo Han, Zhou-Xin Yang, Ying Chi, You-Wei Wang, Tao Wang, Yue-Ru Ji, Ping Yang, Lei Meng, Zhong-Chao Ha. [Comparative study of biological characteristics of human umbilical cord and placental chorionic villous mesenchymal stem cells]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 3. 2013-05-16. PMID:22739184. |
cells expressed the msc surface markers cd90, cd73 and cd105 and cd44, not expressed cd45 and of cd11b and cd34.these cells could differentiate into osteoblasts and adipoblasts under culture with different conditioned medium, but in the adipogenic differentiation of cv-msc, the larger lipid droplets appeared. |
2013-05-16 |
2023-08-12 |
human |
| Shwetha Mureli, Christopher P Gans, Dan J Bare, David L Geenen, Nalin M Kumar, Kathrin Banac. Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling. American journal of physiology. Heart and circulatory physiology. vol 304. issue 4. 2013-04-15. PMID:23241322. |
in hl-1 monolayers supplemented with msc conditioned media (conm) or tyrode (cont) θ significantly increased in a time-dependent manner (cont: t(0h): 2.4 cm/s ± 0.2; t(4h): 3.1 ± 0.4 cm/s), whereas the beating frequency remained constant. |
2013-04-15 |
2023-08-12 |
Not clear |
| Aram Mokarizadeh, Nowruz Delirezh, Ahmad Morshedi, Ghasem Mosayebi, Amir-Abbas Farshid, Karim Mardan. Microvesicles derived from mesenchymal stem cells: potent organelles for induction of tolerogenic signaling. Immunology letters. vol 147. issue 1-2. 2013-01-14. PMID:22705267. |
here, mvs were isolated from mesenchymal stem cell (msc) cultures' conditioned medium. |
2013-01-14 |
2023-08-12 |
mouse |
| M R Moniri, X-Y Sun, J Rayat, D Dai, Z Ao, Z He, C B Verchere, L-J Dai, G L Warnoc. TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells. Cancer gene therapy. vol 19. issue 9. 2013-01-02. PMID:22767216. |
pancreatic cancer cell death was proportionally related to conditioned media from msc(nstrail) and msc(sttrail). |
2013-01-02 |
2023-08-12 |
Not clear |
| J Li, S Liu, W Li, S Hu, J Xiong, X Shu, Q Hu, Q Zheng, Z Son. Vascular smooth muscle cell apoptosis promotes transplant arteriosclerosis through inducing the production of SDF-1α. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. vol 12. issue 8. 2012-12-26. PMID:22845908. |
conditioned media from ltv-p53-transferred smcs activated pi3k/akt/mtor and mapk/erk signaling in a sdf-1α-dependent manner and thereby promoted mesenchymal stem cell (msc) migration and proliferation. |
2012-12-26 |
2023-08-12 |
rat |
| Fei Zheng, Xia Li, Lei Zhang, Xia Kong, Ling-Yun Guo, Jian-Ye Yang, Yong-Zhang Huang, Jun-Ming Tang, Jia-Ning Wan. [Effect of conditioned medium of mesenchymal stem cells on proliferation, migration and adhesion of human umbilical vein endothelial cells]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 1. 2012-12-20. PMID:22391187. |
the aim of this study was to explore the effect of mesenchymal stem cell (msc) conditioned medium (msc-cm) on proliferation, migration and adhesion of human umbilical vein endothelial cell (crl1730) and its mechanism. |
2012-12-20 |
2023-08-12 |
human |
| Fei Zheng, Xia Li, Lei Zhang, Xia Kong, Ling-Yun Guo, Jian-Ye Yang, Yong-Zhang Huang, Jun-Ming Tang, Jia-Ning Wan. [Effect of conditioned medium of mesenchymal stem cells on proliferation, migration and adhesion of human umbilical vein endothelial cells]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 1. 2012-12-20. PMID:22391187. |
msc were treated and cultured for 3 d, the msc-cm or msc overexpressing stem cell-derived factor-1 (sdf-1) conditioned medium (ad-sdf-1-msc-cm) were collected. |
2012-12-20 |
2023-08-12 |
human |
| Sarah Tzu-Feng Hsiao, Azar Asgari, Zerina Lokmic, Rodney Sinclair, Gregory James Dusting, Shiang Yong Lim, Rodney James Dille. Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissue. Stem cells and development. vol 21. issue 12. 2012-12-11. PMID:22188562. |
analysis of conditioned media (cm) protein confirmed the comparable level of angiogenin and vegf-a secretion in all msc populations and showed that dscs and dpcs produced significantly higher concentrations of leptin. |
2012-12-11 |
2023-08-12 |
human |
| P Fidelis-de-Oliveira, J P S Werneck-de-Castro, V Pinho-Ribeiro, B C M Shalom, J H Nascimento-Silva, R H Costa e Souza, I S Cruz, R R Rangel, R C S Goldenberg, A C Campos-de-Carvalh. Soluble factors from multipotent mesenchymal stromal cells have antinecrotic effect on cardiomyocytes in vitro and improve cardiac function in infarcted rat hearts. Cell transplantation. vol 21. issue 5. 2012-11-01. PMID:22305373. |
for this purpose, conditioned medium (cm) was obtained after three passages from msc cultures submitted to 72 h of conditioning in serum-free dmem under normoxia (ncm) or hypoxia (hcm) conditions. |
2012-11-01 |
2023-08-12 |
rat |
| Robert A Boomsma, David L Geene. Mesenchymal stem cells secrete multiple cytokines that promote angiogenesis and have contrasting effects on chemotaxis and apoptosis. PloS one. vol 7. issue 4. 2012-09-13. PMID:22558198. |
conditioned media (cm) was prepared by culturing msc for 48 hours. |
2012-09-13 |
2023-08-12 |
Not clear |