| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathilde Soulez, Isabelle Sirois, Nathalie Brassard, Marc-André Raymond, Frédéric Nicodème, Nicolas Noiseux, Yves Durocher, Alexei V Pshezhetsky, Marie-Josée Héber. Epidermal growth factor and perlecan fragments produced by apoptotic endothelial cells co-ordinately activate ERK1/2-dependent antiapoptotic pathways in mesenchymal stem cells. Stem cells (Dayton, Ohio). vol 28. issue 4. 2010-06-18. PMID:20201065. |
lg3 interacts with beta1-integrins, which triggers downstream erk1/2 activation in msc, albeit to a lesser degree than medium conditioned by apoptotic ec. |
2010-06-18 |
2023-08-12 |
human |
| Benjamin W Fischer-Valuck, Bonnie L Barrilleaux, Donald G Phinney, Katie C Russell, Darwin J Prockop, Kim C O'Conno. Migratory response of mesenchymal stem cells to macrophage migration inhibitory factor and its antagonist as a function of colony-forming efficiency. Biotechnology letters. vol 32. issue 1. 2010-03-04. PMID:19705068. |
at this concentration, iso-1 increased migration to conditioned medium from bronchial epithelial cell cultures by >or=3-fold for all donor msc preparations (p < 0.05). |
2010-03-04 |
2023-08-12 |
human |
| Sonia C Picinich, John W Glod, Debabrata Banerje. Protein kinase C zeta regulates interleukin-8-mediated stromal-derived factor-1 expression and migration of human mesenchymal stromal cells. Experimental cell research. vol 316. issue 4. 2010-03-02. PMID:19944094. |
in a functional assay, activation of pkc is required for in vitro msc migration in response to tumor conditioned medium. |
2010-03-02 |
2023-08-12 |
human |
| Tian Sheng Chen, Ruenn Chai Lai, May May Lee, Andre Boon Hwa Choo, Chuen Neng Lee, Sai Kiang Li. Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic acids research. vol 38. issue 1. 2010-02-12. PMID:19850715. |
we observed that human embryonic stem cell (hesc)-derived msc conditioned medium contained small rnas (less than 300 nt) encapsulated in cholesterol-rich phospholipid vesicles as evidenced by their rnase sensitivity only in the presence of a sodium dodecyl sulfate-based cell lysis buffer, phospholipase a2 and a chelator of cholesterol, cyclodextrin and the restoration of their lower than expected density by detergent or phospholipase a2 treatment. |
2010-02-12 |
2023-08-12 |
human |
| Bonnie L Barrilleaux, Donald G Phinney, Benjamin W Fischer-Valuck, Katie C Russell, Guoshun Wang, Darwin J Prockop, Kim C O'Conno. Small-molecule antagonist of macrophage migration inhibitory factor enhances migratory response of mesenchymal stem cells to bronchial epithelial cells. Tissue engineering. Part A. vol 15. issue 9. 2009-10-27. PMID:19260777. |
additionally, the anti-inflammatory agent iso-1, a small-molecule mif antagonist, further increased msc migration by nearly fourfold in conditioned epithelial media. |
2009-10-27 |
2023-08-12 |
human |
| Ivy A W Ho, Kelly Y W Chan, Wai-Hoe Ng, Chang M Guo, Kam M Hui, Philip Cheang, Paula Y P La. Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma. Stem cells (Dayton, Ohio). vol 27. issue 6. 2009-09-09. PMID:19489099. |
conversely, the nonmigratory phenotype of poorly migrating msc could be rescued in the presence of either recombinant mmp1 or conditioned medium from the highly migrating mscs. |
2009-09-09 |
2023-08-12 |
human |
| Gregory J Block, Shinya Ohkouchi, France Fung, Joshua Frenkel, Carl Gregory, Radhika Pochampally, Gabriel DiMattia, Deborah E Sullivan, Darwin J Procko. Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1. Stem cells (Dayton, Ohio). vol 27. issue 3. 2009-08-11. PMID:19267325. |
we observed that coculture of mscs with previously uv-irradiated fibroblasts reduced apoptosis of the irradiated cells, but fresh msc conditioned medium was unable reproduce the effect. |
2009-08-11 |
2023-08-12 |
Not clear |
| Fan Zhang, Shirling Tsai, Kaori Kato, Dai Yamanouchi, Chunjie Wang, Shahin Rafii, Bo Liu, K Craig Ken. Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. The Journal of biological chemistry. vol 284. issue 26. 2009-08-06. PMID:19406748. |
in this study we found that although tgf-beta had no direct effect on progenitor cell recruitment, conditioned media derived from vascular smooth muscle cells (vsmc) stimulated with tgf-beta induced migration of both total bone marrow (bm) cells and bm-mesenchymal stem cells (msc) and also induced msc differentiation into smooth muscle like cells. |
2009-08-06 |
2023-08-12 |
rat |
| Fan Zhang, Shirling Tsai, Kaori Kato, Dai Yamanouchi, Chunjie Wang, Shahin Rafii, Bo Liu, K Craig Ken. Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. The Journal of biological chemistry. vol 284. issue 26. 2009-08-06. PMID:19406748. |
recombinant mcp-1 mimicked the stimulatory effect of conditioned media on bm and msc migration. |
2009-08-06 |
2023-08-12 |
rat |
| Na Li, Xiangru Lu, Xiaohui Zhao, Fu-Li Xiang, Anargyros Xenocostas, Morris Karmazyn, Qingping Fen. Endothelial nitric oxide synthase promotes bone marrow stromal cell migration to the ischemic myocardium via upregulation of stromal cell-derived factor-1alpha. Stem cells (Dayton, Ohio). vol 27. issue 4. 2009-06-23. PMID:19353524. |
msc migration was decreased in the presence of conditioned medium derived from enos(-/-) cardiomyocytes but increased in the presence of enos-tg conditioned medium. |
2009-06-23 |
2023-08-12 |
mouse |
| Moutih Rafei, Philippe M Campeau, Adriana Aguilar-Mahecha, Marguerite Buchanan, Patrick Williams, Elena Birman, Shala Yuan, Yoon Kow Young, Marie-Noëlle Boivin, Kathy Forner, Mark Basik, Jacques Galipea. Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner. Journal of immunology (Baltimore, Md. : 1950). vol 182. issue 10. 2009-05-26. PMID:19414750. |
in an effort to decipher msc mode of action, we found that msc conditioned medium inhibits eae-derived cd4 t cell activation by suppressing stat3 phosphorylation via msc-derived ccl2. |
2009-05-26 |
2023-08-12 |
mouse |
| Liwen Lin, King L Chow, Yang Len. Study of hydroxyapatite osteoinductivity with an osteogenic differentiation of mesenchymal stem cells. Journal of biomedical materials research. Part A. vol 89. issue 2. 2009-05-18. PMID:18431794. |
using this mesenchymal stem cells (msc) culture assay, osteoinductivity was also demonstrated to be present in the conditioned medium derived from msc cultured on ha substrates. |
2009-05-18 |
2023-08-12 |
mouse |
| Ana Paula Horn, Rudimar Luiz Frozza, Patrícia Benke Grudzinski, Daniéli Gerhardt, Juliana Bender Hoppe, Alessandra Nejar Bruno, Pedro Chagastelles, Nance Beyer Nardi, Guido Lenz, Christianne Salbeg. Conditioned medium from mesenchymal stem cells induces cell death in organotypic cultures of rat hippocampus and aggravates lesion in a model of oxygen and glucose deprivation. Neuroscience research. vol 63. issue 1. 2009-04-20. PMID:18977399. |
in order to investigate the response of hippocampal tissue to factors secreted by msc and if these factors are neuroprotective in a model of oxygen and glucose deprivation (ogd), we used organotypic hippocampal cultures exposed to conditioned medium from bone marrow-derived msc. |
2009-04-20 |
2023-08-12 |
rat |
| Milki Yokokawa, Shunsuke Ohnishi, Hatsue Ishibashi-Ueda, Hiroaki Obata, Kentaro Otani, Yoshinori Miyahara, Koichi Tanaka, Wataru Shimizu, Kazuo Nakazawa, Kenji Kangawa, Shiro Kamakura, Soichiro Kitamura, Noritoshi Nagay. Transplantation of mesenchymal stem cells improves atrioventricular conduction in a rat model of complete atrioventricular block. Cell transplantation. vol 17. issue 10-11. 2009-02-23. PMID:19181209. |
in vitro experiments demonstrated that mscs secreted a large amount of antifibrotic factors such as hepatocyte growth factor and interleukin-10, and msc conditioned medium inhibited the growth of adult cardiac fibroblasts. |
2009-02-23 |
2023-08-12 |
rat |
| Milki Yokokawa, Shunsuke Ohnishi, Hatsue Ishibashi-Ueda, Hiroaki Obata, Kentaro Otani, Yoshinori Miyahara, Koichi Tanaka, Wataru Shimizu, Kazuo Nakazawa, Kenji Kangawa, Shiro Kamakura, Soichiro Kitamura, Noritoshi Nagay. Transplantation of mesenchymal stem cells improves atrioventricular conduction in a rat model of complete atrioventricular block. Cell transplantation. vol 17. issue 10-11. 2009-02-23. PMID:19181209. |
in addition, local injection of msc conditioned medium recovered av conduction in 2 of 15 rats (13%). |
2009-02-23 |
2023-08-12 |
rat |
| Siang-Yo Lin, Jun Yang, Allen D Everett, Charles V Clevenger, Mythili Koneru, Pravin J Mishra, Barton Kamen, Debabrata Banerjee, John Glo. The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells. Experimental cell research. vol 314. issue 17. 2008-11-03. PMID:18722367. |
using a combination of chromatography and electrospray tandem mass spectrometry we have identified novel soluble signaling molecules that induce msc chemotaxis present in conditioned medium of the breast carcinoma cell line mda-mb231. |
2008-11-03 |
2023-08-12 |
Not clear |
| Joo Youn Oh, Mee Kum Kim, Mi Sun Shin, Hyun Ju Lee, Jung Hwa Ko, Won Ryang Wee, Jin Hak Le. The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury. Stem cells (Dayton, Ohio). vol 26. issue 4. 2008-08-15. PMID:18192235. |
the rats were then randomized into four groups: fresh media, conditioned media derived from the msc culture (msc-cm), msc applied topically to the damaged corneas for 2 hours immediately after the injury or msc-cm applied either once or 3 times per day for 3 consecutive days. |
2008-08-15 |
2023-08-12 |
rat |
| Eoin D O'Cearbhaill, Marie A Punchard, Mary Murphy, Frank P Barry, Peter E McHugh, Valerie Barro. Response of mesenchymal stem cells to the biomechanical environment of the endothelium on a flexible tubular silicone substrate. Biomaterials. vol 29. issue 11. 2008-04-24. PMID:18194813. |
these include the development of msc seeded tissue engineered vascular grafts, targeted or systemic delivery of mscs in the dynamic environment of the coronary artery and understanding the potential pathological calcifying role of mechanically conditioned multipotent cells already present in the vessel wall. |
2008-04-24 |
2023-08-12 |
Not clear |
| Kaiming Liu, Luxiang Chi, Liang Guo, Xianghui Liu, Chunxia Luo, Shanchun Zhang, Guoxiang H. The interactions between brain microvascular endothelial cells and mesenchymal stem cells under hypoxic conditions. Microvascular research. vol 75. issue 1. 2008-03-20. PMID:17662311. |
vascular endothelial growth factor (vegf) and matrix metalloproteinase-9 (mmp-9) were detected in the conditioned media of bmec and msc under normal and hypoxic conditions using elisa. |
2008-03-20 |
2023-08-12 |
human |
| Kaiming Liu, Luxiang Chi, Liang Guo, Xianghui Liu, Chunxia Luo, Shanchun Zhang, Guoxiang H. The interactions between brain microvascular endothelial cells and mesenchymal stem cells under hypoxic conditions. Microvascular research. vol 75. issue 1. 2008-03-20. PMID:17662311. |
under hypoxic conditions, the concentration of vegf and mmp-9 in the conditioned media increased significantly, with greater levels in the msc than the bmec media. |
2008-03-20 |
2023-08-12 |
human |