| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaiming Liu, Luxiang Chi, Liang Guo, Xianghui Liu, Chunxia Luo, Shanchun Zhang, Guoxiang H. The interactions between brain microvascular endothelial cells and mesenchymal stem cells under hypoxic conditions. Microvascular research. vol 75. issue 1. 2008-03-20. PMID:17662311. |
under hypoxic conditions, msc conditioned media significantly enhanced the proliferation and migration of bmec. |
2008-03-20 |
2023-08-12 |
human |
| Yin-Ping Li, Sophie Paczesny, Evelyne Lauret, Sonia Poirault, Pierre Bordigoni, Fatiha Mekhloufi, Olivier Hequet, Yves Bertrand, Jing-Ping Ou-Yang, Jean-François Stoltz, Pierre Miossec, Assia Eljaafar. Human mesenchymal stem cells license adult CD34+ hemopoietic progenitor cells to differentiate into regulatory dendritic cells through activation of the Notch pathway. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 3. 2008-03-17. PMID:18209056. |
conditioned medium from msc cultures showed some inhibitory effect independent of il-6, m-csf, and tgf-beta. |
2008-03-17 |
2023-08-12 |
human |
| Leah Forquer Raheja, Damian C Genetos, Clare E Yellowle. Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway. Biochemical and biophysical research communications. vol 366. issue 4. 2008-02-05. PMID:18155656. |
we examined the effect of conditioned media from hypoxic osteocytes on msc migration. |
2008-02-05 |
2023-08-12 |
human |
| Ann H Klopp, Erika L Spaeth, Jennifer L Dembinski, Wendy A Woodward, Anupama Munshi, Raymond E Meyn, James D Cox, Michael Andreeff, Frank C Marin. Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. Cancer research. vol 67. issue 24. 2008-01-15. PMID:18089798. |
to discern the potential mediators involved in msc attraction, in vitro migration assays showed a 50% to 80% increase in msc migration towards conditioned media from 1 to 5 gy-irradiated 4t1 cells compared with unirradiated 4t1 cells. |
2008-01-15 |
2023-08-12 |
mouse |
| A Kate Sasser, Nicholas J Sullivan, Adam W Studebaker, Lindsay F Hendey, Amy E Axel, Brett M Hal. Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 13. 2007-12-03. PMID:17586727. |
paracrine il-6 was found to be the principal mediator of stat3 phosphorylation in coculture studies, and msc induction of stat3 phosphorylation was lost when il-6 was depleted from msc conditioned media or the il-6 receptor was blocked on tumor cells. |
2007-12-03 |
2023-08-12 |
human |
| Chao Peng Ye, Boon Chin Heng, Hua Liu, Wei Seong Toh, Tong Ca. Culture media conditioned by heat-shocked osteoblasts enhances the osteogenesis of bone marrow-derived mesenchymal stromal cells. Cell biochemistry and function. vol 25. issue 3. 2007-11-20. PMID:16927416. |
hence, this study investigated whether a combination of chemical stimuli (ascorbic acid, beta-glycerophosphate and dexamethasone) and culture media conditioned by a human foetal osteoblast cell line (hfob) had any synergistic effect on the osteogenesis of msc. |
2007-11-20 |
2023-08-12 |
human |
| Chao Peng Ye, Boon Chin Heng, Hua Liu, Wei Seong Toh, Tong Ca. Culture media conditioned by heat-shocked osteoblasts enhances the osteogenesis of bone marrow-derived mesenchymal stromal cells. Cell biochemistry and function. vol 25. issue 3. 2007-11-20. PMID:16927416. |
conditioned media with or without prior heat shock treatment (42 degrees c for 1 h) of the hfob cell line, were collected and tested on rabbit msc cultures, in the presence and absence of chemical stimuli. |
2007-11-20 |
2023-08-12 |
human |
| Chao Peng Ye, Boon Chin Heng, Hua Liu, Wei Seong Toh, Tong Ca. Culture media conditioned by heat-shocked osteoblasts enhances the osteogenesis of bone marrow-derived mesenchymal stromal cells. Cell biochemistry and function. vol 25. issue 3. 2007-11-20. PMID:16927416. |
the results showed conclusively that conditioned media promoted osteogenesis of msc, which was further enhanced by prior heat shock-treatment of the hfob cells, as well as by the presence of chemical stimuli. |
2007-11-20 |
2023-08-12 |
human |
| Siu Kwan Sze, Dominique P V de Kleijn, Ruenn Chai Lai, Eileen Khia Way Tan, Hui Zhao, Keng Suan Yeo, Teck Yew Low, Qizhou Lian, Chuen Neng Lee, Wayne Mitchell, Reida Menshawe El Oakley, Sai-Kiang Li. Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells. Molecular & cellular proteomics : MCP. vol 6. issue 10. 2007-11-09. PMID:17565974. |
to evaluate the therapeutic potential of the msc paracrine proteome, a chemically defined serum-free culture medium was conditioned by mscs derived from human embryonic stem cells using a clinically compliant protocol. |
2007-11-09 |
2023-08-12 |
human |
| Farida Djouad, Louis-Marie Charbonnier, Carine Bouffi, Pascale Louis-Plence, Claire Bony, Florence Apparailly, Céline Cantos, Christian Jorgensen, Danièle Noë. Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism. Stem cells (Dayton, Ohio). vol 25. issue 8. 2007-09-26. PMID:17510220. |
moreover, we show that the differentiation of bone marrow progenitors into dc cultured with conditioned supernatants from msc was partly inhibited through the secretion of il-6. |
2007-09-26 |
2023-08-12 |
Not clear |
| Meijing Wang, Wenjun Zhang, Paul Crisostomo, Troy Markel, Kirstan K Meldrum, Xin Y Fu, Daniel R Meldru. STAT3 mediates bone marrow mesenchymal stem cell VEGF production. Journal of molecular and cellular cardiology. vol 42. issue 6. 2007-08-15. PMID:17509611. |
the release of vegf was analyzed by using msc conditioned media under hypoxia or tnf stimulation with or without p38 mapk inhibition. |
2007-08-15 |
2023-08-12 |
mouse |
| Guangwu Xu, Liying Zhang, Guangwen Ren, Zengrong Yuan, Yingyu Zhang, Robert C Zhao, Yufang Sh. Immunosuppressive properties of cloned bone marrow mesenchymal stem cells. Cell research. vol 17. issue 3. 2007-05-14. PMID:17325691. |
conditioned medium from msc cultures showed some inhibitory effect on anti-cd3 induced lymphocyte proliferation independent of pge2 and tgfbeta. |
2007-05-14 |
2023-08-12 |
mouse |
| Karina T Wright, Wagih El Masri, Aheed Osman, Sally Roberts, Giselle Chamberlain, Brian A Ashton, William E B Johnso. Bone marrow stromal cells stimulate neurite outgrowth over neural proteoglycans (CSPG), myelin associated glycoprotein and Nogo-A. Biochemical and biophysical research communications. vol 354. issue 2. 2007-04-10. PMID:17234155. |
whereas conditioned medium from msc cultures stimulated drg neurite outgrowth over type i collagen, it did not promote outgrowth over cspg, mag or nogo-a. |
2007-04-10 |
2023-08-12 |
Not clear |
| Mutsumi Takagi, Yousuke Umetsu, Masashi Fujiwara, Shigeyuki Wakitan. High inoculation cell density could accelerate the differentiation of human bone marrow mesenchymal stem cells to chondrocyte cells. Journal of bioscience and bioengineering. vol 103. issue 1. 2007-03-15. PMID:17298908. |
the increase in the initial density of mscs from 0.05 x 10(4) to 0.9 x 10(4) cells/cm(2) accelerated the increase in the expression level of aggrecan mrna during the differentiation culture for 7 d. the conditioned medium harvested at 7 d from the differentiation culture with an initial msc density of 0.3 x 10(4) cells/cm(2) accelerated the initial increase in the expression level for 3 d in the differentiation culture with an initial msc density of 0.3 x 10(4) cells/cm(2), whereas the conditioned medium harvested at 7 d in the differentiation culture with an initial msc density of 0.05 x 10(4) cells/cm(2) did not. |
2007-03-15 |
2023-08-12 |
human |
| Shunsuke Ohnishi, Bobby Yanagawa, Koichi Tanaka, Yoshinori Miyahara, Hiroaki Obata, Masaharu Kataoka, Makoto Kodama, Hatsue Ishibashi-Ueda, Kenji Kangawa, Soichiro Kitamura, Noritoshi Nagay. Transplantation of mesenchymal stem cells attenuates myocardial injury and dysfunction in a rat model of acute myocarditis. Journal of molecular and cellular cardiology. vol 42. issue 1. 2007-02-27. PMID:17101147. |
in vitro, cultured adult rat cardiomyocytes were injured in response to mcp-1, whereas this effect was attenuated by msc-derived conditioned medium, suggesting cardioprotective effects of msc acting in a paracrine manner. |
2007-02-27 |
2023-08-12 |
rat |
| M Q Islam, J Ringe, E Reichmann, R Migotti, M Sittinger, L da S Meirelles, N B Nardi, P Magnusson, K Isla. Functional characterization of cell hybrids generated by induced fusion of primary porcine mesenchymal stem cells with an immortal murine cell line. Cell and tissue research. vol 326. issue 1. 2006-11-14. PMID:16741712. |
conditioned media from hybrid cells enhance the proliferation of both early-passage and late-passage porcine msc, indicating that the hybrid cells secrete diffusible growth stimulatory factors. |
2006-11-14 |
2023-08-12 |
Not clear |
| Vincent Kindler, Domizio Suva, Caroline Soulas, Bernard Chapui. Haematopoietic stem cells and mesenchymal stem cells as tools for present and future cellular therapies. Swiss medical weekly. vol 136. issue 21-22. 2006-10-27. PMID:16826633. |
for instance, the grafting of native haematopoietic stem cells (hsc) restores haematopoiesis in genetically deficient individuals or in lethally conditioned leukaemic patients, and systemic injection of in vitro amplified mesenchymal stem cells (msc) induces recovery of bone growth in patients with osteogenesis imperfecta. |
2006-10-27 |
2023-08-12 |
Not clear |
| Lorena Santa María, Cecilia V Rojas, José J Minguel. Signals from damaged but not undamaged skeletal muscle induce myogenic differentiation of rat bone-marrow-derived mesenchymal stem cells. Experimental cell research. vol 300. issue 2. 2004-11-24. PMID:15475006. |
we observed that the incubation of msc with a conditioned medium prepared from chemically damaged but not undamaged muscle resulted in a time-dependent change from fibroblast-like into elongated multinucleated cells, a transient increase in the number of myod positive cells, and the subsequent onset of myogenin, alpha-actinin, and myosin heavy chain expression. |
2004-11-24 |
2023-08-12 |
rat |
| Carolina Allers, Walter D Sierralta, Sonia Neubauer, Francisco Rivera, José J Minguell, Paulette A Conge. Dynamic of distribution of human bone marrow-derived mesenchymal stem cells after transplantation into adult unconditioned mice. Transplantation. vol 78. issue 4. 2004-10-07. PMID:15446307. |
animal models have demonstrated that the syngeneic or xenogeneic transplantation of msc results in donor engraftment into the bone marrow and other tissues of conditioned recipients. |
2004-10-07 |
2023-08-12 |
mouse |
| Carolina Allers, Walter D Sierralta, Sonia Neubauer, Francisco Rivera, José J Minguell, Paulette A Conge. Dynamic of distribution of human bone marrow-derived mesenchymal stem cells after transplantation into adult unconditioned mice. Transplantation. vol 78. issue 4. 2004-10-07. PMID:15446307. |
however, there are no reliable data showing the fate of human msc infused into conditioned or unconditioned adult recipients. |
2004-10-07 |
2023-08-12 |
mouse |