| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Magatti, Alice Masserdotti, Patrizia Bonassi Signoroni, Elsa Vertua, Francesca Romana Stefani, Antonietta Rosa Silini, Ornella Parolin. B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells. Frontiers in immunology. vol 11. 2021-04-02. PMID:32582218. |
mesenchymal stromal cells (msc) from the amniotic membrane of human term placenta (hamsc), and the conditioned medium generated from their culture (cm-hamsc) offer significant tools for their use in regenerative medicine mainly due to their immunomodulatory properties. |
2021-04-02 |
2023-08-13 |
human |
| Gautier Tejedor, Patricia Luz-Crawford, Audrey Barthelaix, Karine Toupet, Sébastien Roudières, François Autelitano, Christian Jorgensen, Farida Djoua. MANF Produced by MRL Mouse-Derived Mesenchymal Stem Cells Is Pro-regenerative and Protects From Osteoarthritis. Frontiers in cell and developmental biology. vol 9. 2021-03-20. PMID:33738280. |
this higher migration potential is mediated, in part, by mrl msc-secreted products since mrl msc conditioned medium that contains a complex of released factors significantly increased the migration potential of bl6 msc. |
2021-03-20 |
2023-08-13 |
mouse |
| Santiago Roura, Marta Monguió-Tortajada, Micaela Munizaga-Larroudé, Marta Clos-Sansalvador, Marcella Franquesa, Anna Rosell, Francesc E Borrà. Potential of Extracellular Vesicle-Associated TSG-6 from Adipose Mesenchymal Stromal Cells in Traumatic Brain Injury. International journal of molecular sciences. vol 21. issue 18. 2021-02-24. PMID:32942629. |
in this context, in particular, we discuss the very robust set of findings by jha and colleagues, and the opportunity to potentially extend their research focus on ev isolated in concentrated conditioned media (ccm) from adipose tissue derived msc (asc). |
2021-02-24 |
2023-08-13 |
mouse |
| Maria Antònia Forteza-Genestra, Miquel Antich-Rosselló, Javier Calvo, Antoni Gayà, Marta Monjo, Joana Maria Rami. Purity Determines the Effect of Extracellular Vesicles Derived from Mesenchymal Stromal Cells. Cells. vol 9. issue 2. 2021-02-16. PMID:32059497. |
our aim was to compare the effects of evs isolated by ultracentrifugation from human umbilical cord msc conditioned media obtained using these two conditions: with ev-depleted fbs (uc) or without fbs (uc |
2021-02-16 |
2023-08-13 |
human |
| Mario Simental-Mendía, Sonia Amelia Lozano-Sepúlveda, Vanessa Pérez-Silos, Lizeth Fuentes-Mera, Herminia Guadalupe Martínez-Rodríguez, Carlos Alberto Acosta-Olivo, Víctor Manuel Peña-Martínez, Félix Vilchez-Cavazo. Anti‑inflammatory and anti‑catabolic effect of non‑animal stabilized hyaluronic acid and mesenchymal stem cell‑conditioned medium in an osteoarthritis coculture model. Molecular medicine reports. vol 21. issue 5. 2021-02-16. PMID:32323772. |
we aimed to evaluate and compare the anti‑inflammatory effect of nasha and msc conditioned medium (stem cell‑conditioned medium; sc‑cm), in an explant‑based coculture model of oa. |
2021-02-16 |
2023-08-13 |
Not clear |
| Hualing Sun, Richard E Pratt, Conrad P Hodgkinson, Victor J Dza. Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy. American journal of physiology. Cell physiology. vol 319. issue 6. 2021-01-07. PMID:33026832. |
to identify the active paracrine factors released by macrophages in response to stimulation by msc conditioned media we used an antibody array, identifying increased expression of the angiogenesis-related proteins stromal cell-derived factor 1 (sdf1) and plasminogen activator inhibitor-1 (pai-1). |
2021-01-07 |
2023-08-13 |
mouse |
| Hualing Sun, Richard E Pratt, Conrad P Hodgkinson, Victor J Dza. Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy. American journal of physiology. Cell physiology. vol 319. issue 6. 2021-01-07. PMID:33026832. |
knockdown of either protein inhibited the ability of conditioned media derived from msc paracrine factor-stimulated macrophages to induce ec differentiation both in vitro and in vivo. |
2021-01-07 |
2023-08-13 |
mouse |
| Yu-Hee Kim, Kyung-Ah Cho, Hyun-Ji Lee, Minhwa Park, Sang-Jin Shin, Joo-Won Park, So-Youn Woo, Kyung-Ha Ry. Conditioned Medium from Human Tonsil-Derived Mesenchymal Stem Cells Enhances Bone Marrow Engraftment via Endothelial Cell Restoration by Pleiotrophin. Cells. vol 9. issue 1. 2021-01-06. PMID:31952360. |
the present study aimed to define whether msc conditioned medium could recapitulate the effects of msc cotransplantation. |
2021-01-06 |
2023-08-13 |
mouse |
| Yu-Hee Kim, Kyung-Ah Cho, Hyun-Ji Lee, Minhwa Park, Sang-Jin Shin, Joo-Won Park, So-Youn Woo, Kyung-Ha Ry. Conditioned Medium from Human Tonsil-Derived Mesenchymal Stem Cells Enhances Bone Marrow Engraftment via Endothelial Cell Restoration by Pleiotrophin. Cells. vol 9. issue 1. 2021-01-06. PMID:31952360. |
bm cells (bmcs) isolated from c57bl/6 mice were transplanted via tail vein with or without tonsil-derived msc conditioned medium (t-msc cm). |
2021-01-06 |
2023-08-13 |
mouse |
| b' Krist\\xc3\\xadna Hu\\xc5\\x88\\xc3\\xa1kov\\xc3\\xa1, Mari\\xc3\\xa1n Hluch\\xc3\\xbd, T\\xc3\\xadmea \\xc5\\xa0pakov\\xc3\\xa1, Jana Matejov\\xc3\\xa1, Dagmar Mudro\\xc5\\x88ov\\xc3\\xa1, M\\xc3\\xa1ria Kuricov\\xc3\\xa1, J\\xc3\\xa1n Rosocha, Valent Ledeck\\xc3\\xb. Study of bilateral elbow joint osteoarthritis treatment using conditioned medium from allogeneic adipose tissue-derived MSCs in Labrador retrievers. Research in veterinary science. vol 132. 2020-12-30. PMID:32805699.' |
in this study, conditioned medium from allogeneic canine adipose tissue - derived msc (cm-ad-msc) was prepared and administered into both elbow joints with oa in six labrador retriever dogs (n = 6) on day 0 and 14 without creating a control group with a placebo. |
2020-12-30 |
2023-08-13 |
Not clear |
| Xiu Yu, Li Yu, Bingxin Guo, Rongchang Chen, Chen Qi. A narrative review of research advances in mesenchymal stem cell therapy for asthma. Annals of translational medicine. vol 8. issue 21. 2020-12-16. PMID:33313206. |
it was found that mscs have therapeutic effects on allergic asthma, non-allergic asthma and occupational asthma; gene-modified or pretreated mscs improves the therapeutic effects of mscs in asthma; msc-derived conditioned medium or extracellular vesicles possess the considerable curative effect as msc on asthma; and mscs exert their therapeutic effects on asthma by restoring th1/th2 balance, reversing th17/tregs imbalance, inhibiting dc maturation, and promoting the switch of m1 to m2 and repairing epithelial injury. |
2020-12-16 |
2023-08-13 |
Not clear |
| Luciana Souza-Moreira, Vinicius Cardoso Soares, Suelen da Silva Gomes Dias, Patricia T Bozz. Adipose-derived Mesenchymal Stromal Cells Modulate Lipid Metabolism and Lipid Droplet Biogenesis via AKT/mTOR -PPARγ Signalling in Macrophages. Scientific reports. vol 9. issue 1. 2020-11-13. PMID:31889120. |
previous research demonstrated that murine adipose-derived msc conditioned medium (asccm) reprograms macrophages to an m2-like phenotype which protects from experimental colitis and sepsis. |
2020-11-13 |
2023-08-13 |
Not clear |
| Luciana Souza-Moreira, Vinicius Cardoso Soares, Suelen da Silva Gomes Dias, Patricia T Bozz. Adipose-derived Mesenchymal Stromal Cells Modulate Lipid Metabolism and Lipid Droplet Biogenesis via AKT/mTOR -PPARγ Signalling in Macrophages. Scientific reports. vol 9. issue 1. 2020-11-13. PMID:31889120. |
adipose-derived msc conditioned medium promotes phosphorylation of akt/mtor pathway proteins in macrophages. |
2020-11-13 |
2023-08-13 |
Not clear |
| b' Dobroslava Buj\\xc5\\x88\\xc3\\xa1kov\\xc3\\xa1, Anna \\xc4\\x8cuvalov\\xc3\\xa1, Milan \\xc4\\x8c\\xc3\\xad\\xc5\\xbeek, Filip Humenik, Michel Salzet, Da\\xc5\\xa1a \\xc4\\x8c\\xc3\\xad\\xc5\\xbekov\\xc3\\xa. Canine Bone Marrow Mesenchymal Stem Cell Conditioned Media Affect Bacterial Growth, Biofilm-Associated Microorganisms. vol 8. issue 10. 2020-11-03. PMID:32993120.' |
canine bone marrow mesenchymal stem cell conditioned media affect bacterial growth, biofilm-associated the present study investigated the in vitro antibacterial, antibiofilm and anti-quorum sensing (anti-qs) activities of canine bone marrow mesenchymal stem cell-conditioned media (cbm msc cm) containing all secreted factors <30 k, using a disc diffusion test (ddt), spectrophotometric crystal violet assay (scva) and bioluminescence assay (ba) with qs-reporter |
2020-11-03 |
2023-08-13 |
Not clear |
| Sara Werner, Jana Lützkendorf, Thomas Müller, Lutz P Müller, Guido Poser. MRTF-A controls myofibroblastic differentiation of human multipotent stromal cells and their tumour-supporting function in xenograft models. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31409840. |
recombinant tgf-β1 or tumour cell conditioned medium (tcm) elevated α-sma, calponin 1 and collagen 1 a1 (col1a1) amount on mrna and protein level in msc. |
2020-10-26 |
2023-08-13 |
human |
| Nupur Kohli, Ibtesam R T Al-Delfi, Martyn Snow, Takumi Sakamoto, Tsuyoshi Miyazaki, Hideaki Nakajima, Kenzo Uchida, William E B Johnso. CD271-selected mesenchymal stem cells from adipose tissue enhance cartilage repair and are less angiogenic than plastic adherent mesenchymal stem cells. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:30816233. |
conditioned medium from cd271+ msc cultures was less angiogenic than pa msc conditioned medium, and had little effect on endothelial cell migration or endothelial tubule formation in vitro. |
2020-10-20 |
2023-08-13 |
rat |
| Lei Zhang, Yan Wang, Junjie Ma, Xingqiang Lai, Jiali Fang, Guanghui Li, Lu Xu, Guanghui Pan, Zheng Che. Exogenous MSCs ameliorate hypoxia/reoxygenation injury in renal tubular epithelial cells through JAK/STAT signaling pathway-mediated regulation of HMGB1. American journal of translational research. vol 9. issue 5. 2020-09-29. PMID:28559991. |
after treatment with msc conditioned medium (mscs cm), wp1066, or socs, the expression of these proteins was significantly down-regulated. |
2020-09-29 |
2023-08-13 |
Not clear |
| Maria L Alonso-Alonso, Girish K Srivastava, Ricardo Usategui-Martín, Maria T García-Gutierrez, José Carlos Pastor, Ivan Fernandez-Buen. Mesenchymal Stem Cell Secretome Enhancement by Nicotinamide and Vasoactive Intestinal Peptide: A New Therapeutic Approach for Retinal Degenerative Diseases. Stem cells international. vol 2020. 2020-09-28. PMID:32676122. |
our purpose was to develop different pharmaceutical compositions based on conditioned medium (cm) of adipose msc (amsc) stimulated by and/or combined with nicotinamide (nic), vasoactive intestinal peptide (vip), or both factors; and to evaluate |
2020-09-28 |
2023-08-13 |
Not clear |
| Yang-Zhao Zhou, Zhao Cheng, Yin Wu, Qi-Ying Wu, Xiao-Bo Liao, Yuan Zhao, Jian-Ming Li, Xin-Min Zhou, Xian-Ming F. Mesenchymal stem cell-derived conditioned medium attenuate angiotensin II-induced aortic aneurysm growth by modulating macrophage polarization. Journal of cellular and molecular medicine. vol 23. issue 12. 2020-09-22. PMID:31583844. |
the current study aimed to investigate the therapeutic effects and potential mechanisms of murine bone marrow msc (bm-mscs)-derived conditioned medium (mscs-cm) on angiotensin ii (angii)-induced aa in apolipoprotein e-deficient (apoe |
2020-09-22 |
2023-08-13 |
Not clear |
| Dylan Shearer, Madison O Mervis, Eugene Manley, Anita B Reddy, Andrea I Alfor. TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro. Connective tissue research. vol 60. issue 5. 2020-08-20. PMID:30939949. |
relative lopp levels were elevated compared to wt in msc conditioned medium from female tsp-deficient mice. |
2020-08-20 |
2023-08-13 |
mouse |