| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Augustine M Saiz, Marissa A Gionet-Gonzales, Mark A Lee, J Kent Leac. Conditioning of myoblast secretome using mesenchymal stem/stromal cell spheroids improves bone repair. Bone. vol 125. 2020-08-03. PMID:31102712. |
conditioned media from msc spheroids increased osteogenic response of mc3t3 pre-osteoblasts compared to myokines from l6 myoblasts alone. |
2020-08-03 |
2023-08-13 |
rat |
| Augustine M Saiz, Marissa A Gionet-Gonzales, Mark A Lee, J Kent Leac. Conditioning of myoblast secretome using mesenchymal stem/stromal cell spheroids improves bone repair. Bone. vol 125. 2020-08-03. PMID:31102712. |
this effect was synergistically enhanced when conditioned media of msc spheroids was serially delivered to myoblasts and then osteoprogenitor cells in vitro. |
2020-08-03 |
2023-08-13 |
rat |
| Owen Hovey, Roya Pasha, Zoe Lehmann, Nicolas Pineaul. Insights into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics. Proteomics. 2020-07-15. PMID:32666692. |
similarly, mesenchymal stromal cells (msc)-derived osteoblast (m-ost) conditioned media (ocm) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. |
2020-07-15 |
2023-08-13 |
Not clear |
| Owen Hovey, Roya Pasha, Zoe Lehmann, Nicolas Pineaul. Insights into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics. Proteomics. 2020-07-15. PMID:32666692. |
over 300 proteins were quantified by mass spectroscopy in media conditioned with msc or m-ost, with 47 being differentially expressed. |
2020-07-15 |
2023-08-13 |
Not clear |
| Wenbo Chen, Yaying Sun, Xueping Gu, Yuefeng Hao, Xingwang Liu, Jinrong Lin, Jiwu Chen, Shiyi Che. Conditioned medium of mesenchymal stem cells delays osteoarthritis progression in a rat model by protecting subchondral bone, maintaining matrix homeostasis, and enhancing autophagy. Journal of tissue engineering and regenerative medicine. vol 13. issue 9. 2020-07-08. PMID:31210406. |
evidence accumulated that mesenchymal stem cell (msc) therapy ameliorated osteoarthritis (oa) via paracrine effect, whereas conditioned medium (cm) of mscs contains all the secretomes. |
2020-07-08 |
2023-08-13 |
rat |
| Jihyun Jung, Junha Jeong, Hyun Sook Hon. Substance P improves MSC-mediated RPE regeneration by modulating PDGF-BB. Biochemical and biophysical research communications. vol 515. issue 4. 2020-07-06. PMID:31176487. |
the mscs were primed with sp followed by the addition of conditioned medium (msc |
2020-07-06 |
2023-08-13 |
Not clear |
| Ching-Hsuan Hu, Yi-Wen Tseng, Chih-Yung Chiou, Kuan-Chun Lan, Chih-Hung Chou, Chun-San Tai, Hsien-Da Huang, Chiung-Wen Hu, Ko-Hsun Liao, Shiow-Shuh Chuang, Jui-Yung Yang, Oscar K Le. Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model. Stem cell research & therapy. vol 10. issue 1. 2020-07-01. PMID:31462299. |
mesenchymal stem cell (msc) conditioned medium (cm) has therapeutic effects on wound healing and preventing hs formation. |
2020-07-01 |
2023-08-13 |
rabbit |
| Carmela Giampà, Alessandra Alvino, Marta Magatti, Antonietta R Silini, Antonella Cardinale, Emanuela Paldino, Francesca R Fusco, Ornella Parolin. Conditioned medium from amniotic cells protects striatal degeneration and ameliorates motor deficits in the R6/2 mouse model of Huntington's disease. Journal of cellular and molecular medicine. vol 23. issue 2. 2020-06-17. PMID:30585395. |
mesenchymal stem/stromal cells (msc) from the amniotic membrane (hamsc), and their conditioned medium (cm-hamsc), have been shown to possess protective effects in vitro and in vivo in animal models of immune-based disorders and of traumatic brain injury, which have been shown to be mediated by their immunomodulatory properties. |
2020-06-17 |
2023-08-13 |
mouse |
| Biji Mathew, Sriram Ravindran, Xiaorong Liu, Leianne Torres, Mohansrinivas Chennakesavalu, Chun-Chieh Huang, Liang Feng, Ruth Zelka, Jasmine Lopez, Monica Sharma, Steven Rot. Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion. Biomaterials. vol 197. 2020-05-21. PMID:30654160. |
based upon the hypothesis that the neuroprotective effects of mscs and conditioned medium are largely mediated by extracellular vesicles (evs), msc derived evs were tested in an in-vitro oxygen-glucose deprivation (ogd) model of retinal ischemia. |
2020-05-21 |
2023-08-13 |
human |
| Fatemeh Soleimanifar, Fatemeh Sadat Hosseini, Hadi Atabati, Asma Behdari, Ladan Kabiri, Seyed Ehsan Enderami, Mohammad-Mehdi Khani, Abdolreza Ardeshirylajimi, Ehsan Sabur. Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers. Journal of cellular physiology. vol 234. issue 7. 2020-05-04. PMID:30378123. |
recently, it has been determined that mesenchymal stem cell (msc)-derived conditioned medium (cm) contains effective factors in the bone formation process. |
2020-05-04 |
2023-08-13 |
human |
| Chimobi Emukah, Evan Dittmar, Rija Naqvi, John Martinez, Alexis Corral, Axel Moreira, Alvaro Moreir. Mesenchymal stromal cell conditioned media for lung disease: a systematic review and meta-analysis of preclinical studies. Respiratory research. vol 20. issue 1. 2020-04-23. PMID:31666086. |
preclinical studies suggest that mesenchymal stromal cell (msc) conditioned media (cdm) can attenuate inflammation. |
2020-04-23 |
2023-08-13 |
Not clear |
| Fumihiko Namb. Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia. Pediatrics international : official journal of the Japan Pediatric Society. vol 61. issue 10. 2020-03-24. PMID:31487104. |
cell-free preparations derived from msc, including conditioned media and exosomes, remain a pre-clinical technology despite their great clinical potential. |
2020-03-24 |
2023-08-13 |
human |
| Philipp M Wörner, Deborah J Schächtele, Zahra Barabadi, Sudesh Srivastav, Bysani Chandrasekar, Reza Izadpanah, Eckhard U Al. Breast Tumor Microenvironment Can Transform Naive Mesenchymal Stem Cells into Tumor-Forming Cells in Nude Mice. Stem cells and development. vol 28. issue 5. 2020-03-05. PMID:30572805. |
furthermore, when naive mscs preexposed to mda-mb231-derived conditioned medium (cm; msc |
2020-03-05 |
2023-08-13 |
mouse |
| Praveen Kumar L, Sangeetha Kandoi, Ranjita Misra, Vijayalakshmi S, Rajagopal K, Rama Shanker Verm. The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine. Cytokine & growth factor reviews. vol 46. 2020-02-28. PMID:30954374. |
understanding the secretome of in vitro cultured msc populations, by the analysis of the corresponding conditioned medium, will enable us to evaluate its utility as a new therapeutic option. |
2020-02-28 |
2023-08-13 |
Not clear |
| Ahmad Abu-Khader, Kyle W Law, Suria Jahan, Javed K Manesia, Roya Pasha, Owen Hovey, Nicolas Pineaul. Paracrine Factors Released by Osteoblasts Provide Strong Platelet Engraftment Properties. Stem cells (Dayton, Ohio). vol 37. issue 3. 2020-02-27. PMID:30520180. |
serum-free medium conditioned with osteoblasts (i.e., osteoblast-conditioned medium [ocm]) derived from mesenchymal stromal cells (msc) was previously shown to increase cell growth and raise the levels of human platelets in mice transplanted with ocm-expanded progenitors. |
2020-02-27 |
2023-08-13 |
mouse |
| Ahmad Abu-Khader, Kyle W Law, Suria Jahan, Javed K Manesia, Roya Pasha, Owen Hovey, Nicolas Pineaul. Paracrine Factors Released by Osteoblasts Provide Strong Platelet Engraftment Properties. Stem cells (Dayton, Ohio). vol 37. issue 3. 2020-02-27. PMID:30520180. |
insulin-like growth factor (igf)-2 was found to be present at higher levels in ocm than in control medium conditioned with msc. |
2020-02-27 |
2023-08-13 |
mouse |
| Richard H Adams, Todd A Casto. Probabilistic Species Tree Distances: Implementing the Multispecies Coalescent to Compare Species Trees Within the Same Model-Based Framework Used to Estimate Them. Systematic biology. vol 69. issue 1. 2020-01-15. PMID:31086978. |
multispecies coalescent (msc) models parameterize the discrete probability distribution of gene trees conditioned upon a species tree with a particular topology and set of divergence times (in coalescent units), and thus provide a framework for measuring distances between species tree models in terms of their corresponding gene tree topology probabilities. |
2020-01-15 |
2023-08-13 |
Not clear |
| Pardis Saeedi, Raheleh Halabian, Abbas Ali Imani Foolad. Mesenchymal stem cells preconditioned by staphylococcal enterotoxin B enhance survival and bacterial clearance in murine sepsis model. Cytotherapy. vol 21. issue 1. 2019-12-10. PMID:30477894. |
the expression levels of apoptosis genes and antibacterial activity of msc and seb-msc and their conditioned medium (cm), as well as cell survival, were studied in vitro in an oxidative stress and serum deprivation condition. |
2019-12-10 |
2023-08-13 |
mouse |
| N V Bogatcheva, M E Colema. Conditioned Medium of Mesenchymal Stromal Cells: A New Class of Therapeutics. Biochemistry. Biokhimiia. vol 84. issue 11. 2019-11-28. PMID:31760924. |
this review (i) describes currently conducted clinical trials of cell-free products containing msc secretome; (ii) summarizes main approaches to the generation and characterization of conditioned media concentrates and extracellular vesicle isolates; (iii) analyzes a variety of preclinical studies where effectiveness of secretome products has been shown; and (iv) summarizes current knowledge about secretome bioactive components obtained by analysis of in vivo models testing the therapeutic potential of the msc secretome. |
2019-11-28 |
2023-08-13 |
Not clear |
| Ningning He, Yangyang Kong, Xudan Lei, Yang Liu, Jinhan Wang, Chang Xu, Yan Wang, Liqing Du, Kaihua Ji, Qin Wang, Zongjin Li, Qiang Li. MSCs inhibit tumor progression and enhance radiosensitivity of breast cancer cells by down-regulating Stat3 signaling pathway. Cell death & disease. vol 9. issue 10. 2019-11-13. PMID:30297887. |
here, we investigated the potential of msc conditioned medium (msc-cm) in sensitizing breast cancer to radiotherapy. |
2019-11-13 |
2023-08-13 |
Not clear |