| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ai-Qin Qi, Yan-Hui Zhang, Qin-De Qi, Ye-Hui Liu, Jun-Ling Zh. Overexpressed HspB6 Underlines a Novel Inhibitory Role in Kainic Acid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKA Pathway. Cellular and molecular neurobiology. vol 39. issue 1. 2019-04-08. PMID:30511325. |
additionally, hspb6 phosphorylation further augments the inhibitory effects of hspb6 on the inflammatory response and hippocampal neuronal apoptosis. |
2019-04-08 |
2023-08-13 |
rat |
| Ai-Qin Qi, Yan-Hui Zhang, Qin-De Qi, Ye-Hui Liu, Jun-Ling Zh. Overexpressed HspB6 Underlines a Novel Inhibitory Role in Kainic Acid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKA Pathway. Cellular and molecular neurobiology. vol 39. issue 1. 2019-04-08. PMID:30511325. |
hspb6 decreased apoptosis signal-regulating kinase 1 (ask1) expression to inhibit inflammatory response and hippocampal neuronal apoptosis. |
2019-04-08 |
2023-08-13 |
rat |
| Junming Fan, Hui Guang, Haizeng Zhang, Danyang Chen, Lu Ding, Xiaofang Fan, Feng Xue, Zhuohui Gan, Yongyu Wang, Sunzhong Mao, Lianggang Hu, Yongsheng Gon. SIRT1 Mediates Apelin-13 in Ameliorating Chronic Normobaric Hypoxia-induced Anxiety-like Behavior by Suppressing NF-κB Pathway in Mice Hippocampus. Neuroscience. vol 381. 2019-04-05. PMID:29680708. |
we also showed that resveratrol treatment decreased il-1β, il-6, tnf-ɑ, pcna, bcl-2, and acetyl-p65 levels, but increased bax and caspase 3 levels in hippocampus, suggesting a suppressive effect of resveratrol on cellular neuroinflammation and proliferation while a promotive effect on apoptosis of microglia in hippocampus. |
2019-04-05 |
2023-08-13 |
mouse |
| Wen Li, Zhenshu Li, Dezheng Zhou, Xumei Zhang, Jing Yan, Guowei Huan. Maternal folic acid deficiency stimulates neural cell apoptosis via miR-34a associated with Bcl-2 in the rat foetal brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 72. 2019-04-03. PMID:30447272. |
maternal folic acid deficiency increased neuronal apoptosis in the hippocampus and the cortex in the offspring. |
2019-04-03 |
2023-08-13 |
rat |
| Shang-Tse Ho, Yueh-Tung Hsieh, Sheng-Yao Wang, Ming-Ju Che. Improving effect of a probiotic mixture on memory and learning abilities in d-galactose-treated aging mice. Journal of dairy science. vol 102. issue 3. 2019-04-03. PMID:30639021. |
results of the morris water maze test indicated that long-term administration of the probiotic mixture improved memory and learning abilities and ameliorated the apoptosis pattern in the hippocampus of aging mice treated with d-galactose. |
2019-04-03 |
2023-08-13 |
mouse |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani-Asl, Alireza Komak. 5-Hydroxytryptamine receptor 6 antagonist, SB258585 exerts neuroprotection in a rat model of Streptozotocin-induced Alzheimer's disease. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29667108. |
the aim of this study was to evaluate the effect of a 5-ht6r antagonist on cognition, learning, memory, and hippocampal apoptosis in an experimental rat model of ad. |
2019-04-01 |
2023-08-13 |
rat |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani-Asl, Alireza Komak. 5-Hydroxytryptamine receptor 6 antagonist, SB258585 exerts neuroprotection in a rat model of Streptozotocin-induced Alzheimer's disease. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29667108. |
tunel staining was used to evaluate apoptosis in the hippocampus. |
2019-04-01 |
2023-08-13 |
rat |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani-Asl, Alireza Komak. 5-Hydroxytryptamine receptor 6 antagonist, SB258585 exerts neuroprotection in a rat model of Streptozotocin-induced Alzheimer's disease. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29667108. |
this study demonstrates that icv stz injections induce apoptosis in hippocampal cells, decrease the nor discrimination index, increase the number of trials needed to reach acquisition and the time spent in the dark compartment during pal, as compared with sham and control groups. |
2019-04-01 |
2023-08-13 |
rat |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani-Asl, Alireza Komak. 5-Hydroxytryptamine receptor 6 antagonist, SB258585 exerts neuroprotection in a rat model of Streptozotocin-induced Alzheimer's disease. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29667108. |
thus, we conclude that long-term administration of the 5-ht6r antagonist sb258585, ameliorates ad-associated cognitive and behavioral impairments through the suppression of apoptosis in the hippocampus. |
2019-04-01 |
2023-08-13 |
rat |
| Feiyan Fan, Jing Qi, Nan Liu, Zhen Wang, Wenshi Wang, Hui Liu, Xiaoshan Xu, Guangfeng Chen, Xin Wang, Hongwei Yang, Mark Johnson, Yanyang Tu, Tao Liu, Jianfang F. TGF-beta/TGF-beta RII/CLC-3 axis promotes cognitive disorders in diabetes. Frontiers in bioscience (Landmark edition). vol 24. 2019-04-01. PMID:30468668. |
transforming growth factor beta (tgf-beta) and chloride channel-3 (clc-3) are critical for inflammatory response, cellular proliferation and apoptosis in hippocampus neurons. |
2019-04-01 |
2023-08-13 |
rat |
| Yanan Li, Xinran Li, Jinghua Zhao, Lina Li, Yuxin Wang, Yiming Zhang, Yu Chen, Wenhan Liu, Li Ga. Midazolam Attenuates Autophagy and Apoptosis Caused by Ketamine by Decreasing Reactive Oxygen Species in the Hippocampus of Fetal Rats. Neuroscience. vol 388. 2019-03-29. PMID:29634998. |
midazolam attenuates autophagy and apoptosis caused by ketamine by decreasing reactive oxygen species in the hippocampus of fetal rats. |
2019-03-29 |
2023-08-13 |
human |
| Kang Ma, Rongwei Li, Hengli Zhao, Jie Qu, Ning Mu, Xin Liu, Shi Wang, Chuanyan Yang, Hua Feng, Liang Tan, Fei L. Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats. Neuroscience. vol 388. 2019-03-29. PMID:30036663. |
this study explores a potential treatment for cognitive dysfunction following sah with the demonstration that multi-target drug cattle encephalon glycoside and ignotin (cegi) can relieve cognitive dysfunction by decreasing hippocampal neuron apoptosis following sah in rats. |
2019-03-29 |
2023-08-13 |
rat |
| Kang Ma, Rongwei Li, Hengli Zhao, Jie Qu, Ning Mu, Xin Liu, Shi Wang, Chuanyan Yang, Hua Feng, Liang Tan, Fei L. Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats. Neuroscience. vol 388. 2019-03-29. PMID:30036663. |
these results indicate that high doses of cegi can decrease hippocampal neuron apoptosis and relieve cognitive dysfunction in rats, suggesting that multitarget-drug cegi exhibits a neuroprotective effect in sah via the mitochondrial apoptosis pathway. |
2019-03-29 |
2023-08-13 |
rat |
| Hao Song, Li-Ping Huang, Yuping Li, Chao Liu, Songhua Wang, Wei Meng, Shanshan Wei, Xin-Ping Liu, Yanchun Gong, Li-Hua Ya. Neuroprotective effects of cordycepin inhibit Aβ-induced apoptosis in hippocampal neurons. Neurotoxicology. vol 68. 2019-03-21. PMID:30031108. |
neuroprotective effects of cordycepin inhibit aβ-induced apoptosis in hippocampal neurons. |
2019-03-21 |
2023-08-13 |
Not clear |
| Xiaoling Zhao, Yue Sun, Yongbo Ding, Jun Zhang, Kezhong L. miR-34a Inhibitor May Effectively Protect against Sevoflurane-Induced Hippocampal Apoptosis through the Wnt/β-Catenin Pathway by Targeting Wnt1. Yonsei medical journal. vol 59. issue 10. 2019-03-21. PMID:30450855. |
mir-34a inhibitor may effectively protect against sevoflurane-induced hippocampal apoptosis through the wnt/β-catenin pathway by targeting wnt1. |
2019-03-21 |
2023-08-13 |
Not clear |
| Xiaoling Zhao, Yue Sun, Yongbo Ding, Jun Zhang, Kezhong L. miR-34a Inhibitor May Effectively Protect against Sevoflurane-Induced Hippocampal Apoptosis through the Wnt/β-Catenin Pathway by Targeting Wnt1. Yonsei medical journal. vol 59. issue 10. 2019-03-21. PMID:30450855. |
mir-34a has been found to negatively regulate ketamine-induced hippocampal apoptosis and memory impairment. |
2019-03-21 |
2023-08-13 |
Not clear |
| Hein Min Latt, Hiroaki Matsushita, Miku Morino, Yuuri Koga, Hiroyuki Michiue, Teiichi Nishiki, Kazuhito Tomizawa, Hideki Matsu. Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons. Neuroscience. vol 379. 2019-03-18. PMID:29596965. |
oxytocin inhibits corticosterone-induced apoptosis in primary hippocampal neurons. |
2019-03-18 |
2023-08-13 |
mouse |
| Hein Min Latt, Hiroaki Matsushita, Miku Morino, Yuuri Koga, Hiroyuki Michiue, Teiichi Nishiki, Kazuhito Tomizawa, Hideki Matsu. Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons. Neuroscience. vol 379. 2019-03-18. PMID:29596965. |
in this study, we showed that ot protects primary mouse hippocampal neurons from cort-induced apoptosis. |
2019-03-18 |
2023-08-13 |
mouse |
| Hein Min Latt, Hiroaki Matsushita, Miku Morino, Yuuri Koga, Hiroyuki Michiue, Teiichi Nishiki, Kazuhito Tomizawa, Hideki Matsu. Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons. Neuroscience. vol 379. 2019-03-18. PMID:29596965. |
cort induced apoptosis in hippocampal neurons, but had no effect on apoptosis in glial cells. |
2019-03-18 |
2023-08-13 |
mouse |
| Hein Min Latt, Hiroaki Matsushita, Miku Morino, Yuuri Koga, Hiroyuki Michiue, Teiichi Nishiki, Kazuhito Tomizawa, Hideki Matsu. Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons. Neuroscience. vol 379. 2019-03-18. PMID:29596965. |
ot inhibited cort-induced apoptosis in primary hippocampal neurons. |
2019-03-18 |
2023-08-13 |
mouse |